Proceedings of the Shevchenko Scientific Society. Medical Sciences最新文献

{"title":"APPLICATION OF NUCLEIC ACID AMPLIFICATION TESTS IN MANAGING COVID-19 PANDEMIC","authors":"S. Souchelnytskyi, N. Souchelnytskyi","doi":"10.25040/ntsh2020.02.04","DOIUrl":"https://doi.org/10.25040/ntsh2020.02.04","url":null,"abstract":"Background. COVID-19 pandemic highlighted an importance of sensitive and specific tests that would be cost-efficient, fast and scalable. There are more than 200 COVID-19 detection tests available worldwide, with every country developing own assays. Sample collection, preparation for a test, tests itself and interpretation of results have a strong impact on the clinical value of the testing. Diversity of tests and workflows requires an analysis of their performance in clinics. Methods. Literature review, analysis of clinical reports, online resources, public and commercial reports were used to collect information about the tests. Collected information was processed for extraction of relevant to this review information. Results. Here we review COVID-19 detection tests that are based on amplification of nucleic acids. The tests employ polymerase chain reaction (PCR) or loop-mediated isothermal amplification (LAMP). Clinical value of the tests depends on used technologies that differ for LAMP, real-time and standard PCR methods. Diversity of sample preparation protocols, different designs of the tests, used chemistries and protocols have significant impact on performance of the tests. Tailoring of a testing workflow to available infrastructure and selection of the most efficient combination of tests and protocols for each step in a testing workflow is crucial for the success. Conclusion. Reviewed here strong and weak sides of different tests and protocols can be of help in selection of a testing workflow for achieving maximal clinical utility.","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114595661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ADVANCES IN SCIENCE EDITING AND COMMUNICATION","authors":"U. Telishevska","doi":"10.25040/ntsh2020.02.02","DOIUrl":"https://doi.org/10.25040/ntsh2020.02.02","url":null,"abstract":"During the first half of 2021 6 more webinars took place online, as a continuation of a series of lectures and workshops for scientists on writing quality of scientific articles, These events were held with the support of Danylo Halytsky Lviv National Medical University, the Shevchenko Scientific Society, the Western Scientific Centre of the National Academy of Sciences of Ukraine, the Ministry of Education and Science of Ukraine and the Council of Scientific Editors of Ukraine. The participants had opportunity to view online broadcasts and recordings of the events at “Рroceedings of the Shevchenko Scientific Society. Medical Sciences” journal Facebook page and Youtube channel (https://www.youtube.com/channel/UC40L7KlZ5UU4hrMj_--yqHw). Each registered participant received a certificate with certain number of points of continuous professional development. Traditionally, webinars were held in English, among the invited speakers were Ukrainian and foreign fellow scientists from Great Britain, Croatia, USA, Iran and India","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130099366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PRIMUM NON NOCERE","authors":"Olga Holubovska","doi":"10.25040/ntsh2020.01.17","DOIUrl":"https://doi.org/10.25040/ntsh2020.01.17","url":null,"abstract":"","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127672812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"LYMPHOCYTAR INFILTRATES IN THE THYROID GLAND OF PATIENTS OPERATED ON THE BASIS OF THYROID PATHOLOGY","authors":"V. Vovk, U. Omelyash","doi":"10.25040/ntsh2019.02.04","DOIUrl":"https://doi.org/10.25040/ntsh2019.02.04","url":null,"abstract":"Методи. З метою визначення складу і особливостей локалізації лімфоцитарних інфільтратів проведено типове патогістологічне та імуногістохімічне дослідження операційного матеріалу 15 хворих, оперованих з приводу автоімунного тиреоїдиту Хашімото, фокального тиреоїдиту та папілярного раку у поєднанні з автоімунним чи фокальним тиреоїдитом з використанням антитіл до розташованих у лімфоцитах антигенів CD3, CD8, CD20 та CD138.","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131040957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ALTA ALATIS PATENT [THE SKY FOR THOSE WHO HAVE WINGS] (ON THE OCCASION OF DR. VASSYL LONCHYNA'S ANNIVERSARY)","authors":"U. Pidvalna","doi":"10.25040/ntsh2019.02.07","DOIUrl":"https://doi.org/10.25040/ntsh2019.02.07","url":null,"abstract":"the medical 2017-2018 he at The MacLean Center Medical Ethics at of Chicago edited the book «Di ffi cult Decisions in Cardiothoracic Critical Care Surgery» (Springer, 2019). He is a member of Plast, The Shevchenko Scienti fi c Society (SSS), The Society of Thorac-ic Surgeons (STS), The European Association for Cardio-Thoracic Surgery (EACTS), The American College of Surgeons (ACS) and The American College of Cardiology (ACC). He has a multifaceted personality with 45 years of physician experience at US clinics. Today, he is an Associate Editor of the journal «Proceedings of the Shevchenko Scienti fi c Society. Medical Sciences.», a lecturer of «Ethics for the physician» course at the School of Bioethics of the Ukrainian Catholic University (Lviv), and an associate of the Cardiac Surgery Department of the Lviv Regional Clinical Hospital. The article brie fl y presents biographical information on the occasion of Mr. Vassyl Lonchyna’s 70th anniversary.","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123782337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE IDEA OF MAINTAINING AND IMPROVING THE HEALTH OF OUR NATION IS PROFESSOR IRYNA DATSENKO’S LIFE MOTTO","authors":"V. Fedorenko","doi":"10.25040/ntsh2019.01.10","DOIUrl":"https://doi.org/10.25040/ntsh2019.01.10","url":null,"abstract":"","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116683965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Historical Milestones of the Department of Neurology at the Danylo Halytski Lviv National Medical University","authors":"H. Ivasiuk, T. Nehrych, Yuriy Matviyenko, N. Bozhenko, V. Krysa","doi":"10.25040/ntsh2019.01.12","DOIUrl":"https://doi.org/10.25040/ntsh2019.01.12","url":null,"abstract":"","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114747983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"DENSITY AND MINERAL CONTENT DYNAMICS OF BONE TISSUE AGAINST THE BACKGROUND OF OPIOID INFLUENCE","authors":"S. Rostyslav, Masna Zoriana","doi":"10.25040/ntsh2019.01.04","DOIUrl":"https://doi.org/10.25040/ntsh2019.01.04","url":null,"abstract":"Introduction. The modern scientific medical literature contains numerous data on the peculiarities of structural transformation of bone tissue and the dynamics of its mineral composition in the age aspect, as well as under the influence of various exo- and endogenous factors. However, data on changes in the mineral component of bone tissue under conditions of long-term opioid exposure have not been identified in the available literature, although the widespread use of opioids in the clinic as drugs with analgesic effect makes this issue especially relevant. \u0000The aim of our research was to study the dynamics of mineral composition of rat bone tissue with prolonged exposure to opioids. \u0000Materials and methods. The study was carried out on 40 sexually mature outbred male rats with a body weight of 180-200 g and aged 3.5 months. Opioid addiction was modeled by the daily (once a day with identical intervals) injection of an opioid pain reliever nalbuphine. Nalbuphine was injected intramuscularly using to the following pattern: 1st week - 8 mg/kg, 2nd week - 15 mg/kg, 3rd week - 20 mg/kg, 4th week - 25 mg/kg, 5th week - 30 mg/kg, 6th week - 35 mg/kg. To determine the mineral composition of the bone tissue of rat's mandible, the method of atomic absorption spectral analysis (AASA) was used, which made it possible to detect eight mineral elements (calcium, phosphorus, magnesium, sodium, potassium, iron, strontium, zinc) in the studied samples. The concentration of  researched elements in bone tissue samples was specified in mg/g. The research of mineral composition of the mandible was performed weekly in the span of 7 weeks of the experiment - 6 weeks of nalbuphine consumption, and then one week after its cessation (5 animals per each experiment period); 5 other animals were attributed to the control group. \u0000Results. The results of this study allowed to determine the quantitative content of all investigated elements in the bone tissue at each stage of the experiment and indicate the presence of their expressed dynamics. Results of the atomic absorption spectral analysis of bone tissue of the rat's mandible body allowed to determine the quantitative content of four macro-elements (Ca, P, Mg, Na) and four microelements (K, Fe, Sr, Zn) and their specific shares in the mineral content of bone tissue in intact animals against the background of nalbuphine consumption and after its cessation. Against the background of nalbuphine consumption and after its cessation, specific shares of the studied macro-and microelements in the mineral component of bone tissue of the rat’s mandible have expressed dynamics - shares of calcium, iron, strontium, and zinc grow and remain higher than normal, and after nalbuphine is no longer administered, while specific shares of phosphorus, sodium, magnesium, and potassium are lower than in intact animals during seven weeks of the experiment. The dynamics of absolute indices of the researched mineral elements against the background of","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"161 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114731181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MYASTHENIA – DIFFICULTIES IN DIAGNOSTICS AND TREATMENT (CLINICAL CASE ANALYSIS)","authors":"T. Nehrych, N. Bozhenko, S. Kirilyuk","doi":"10.25040/ntsh2019.01.08","DOIUrl":"https://doi.org/10.25040/ntsh2019.01.08","url":null,"abstract":"","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129905127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VARIOUS LOCATIONS OF THE THIRD MOLARS IN THE LOWER JAW","authors":"Iryna Palianytsia, B. Chekh, Z. Masna","doi":"10.25040/ntsh2019.01.09","DOIUrl":"https://doi.org/10.25040/ntsh2019.01.09","url":null,"abstract":"Introduction. Wisdom teeth are the most mysterious part of human anatomy because there are still no clear terms when these molars erupt. There are several basic classifications that are based on the following: the angle of inclination and the position of the tooth germ in the bone; the eruption state; location of roots. With the help of screening, which includes a clinical examination and the review of panoramic X-rays, tooth location in the jaw is identified. Today, the removal of third molars without significant reason is very common. There is a debate among foreign doctors about the necessity of these teeth for a person. \u0000Objective. To find out the frequency of eruption, the absence of a dental germ and possible locations for rudiments of the third large angular teeth in the lower jaw of a modern person with a physiologically formed dental bite. \u0000Research methods. Four hundred individuals from the Western region of Ukraine were screened using Panorax to establish various locations of the mandibular third molars. These panoramic X-rays were classified by age, gender, the presence of third molars and the corresponding side of their location. \u0000Results. The sum of teeth is calculated based on the total number of erupted, impacted or missing teeth (separately) on one side in all categories. The percentage ratio of the sum of teeth in a certain group on one side to the total number of teeth on the given side was determined. The percentage ratio of teeth of a certain group on one side for a given age group to the total number of teeth for the same group was determined. \u0000Conclusion. It has been calculated that patients with erupted teeth constitute 35.29% of all individuals. Moreover, 58.5% of them have both wisdom teeth on the lower jaw. This accounts for only 20.65% of all patients. It was revealed that pathological medial location of the third molar was the most frequent. The lingual positioning of the mandibular third molar was the least frequent.","PeriodicalId":140699,"journal":{"name":"Proceedings of the Shevchenko Scientific Society. Medical Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128412149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}