International Journal of Impotence Research最新文献_第2页

Editorial for the special issue on "Endocrine system and sexology". “内分泌系统与性学”特刊社论。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-15 DOI: 10.1038/s41443-025-01117-3

Emmanuele A Jannini

引用次数: 0

Comment on: Male sexual dysfunction associated with GLP-1 receptor agonists: a cross-sectional analysis of FAERS data. 点评：男性性功能障碍与GLP-1受体激动剂相关：FAERS数据的横断面分析。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-15 DOI: 10.1038/s41443-025-01121-7

Taylor P Kohn, Larry I Lipshultz

引用次数: 0

Postoperative complication severity prediction in penile prosthesis implantation: a machine learning-based predictive modeling study. 阴茎假体植入术后并发症严重程度预测：基于机器学习的预测模型研究。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-15 DOI: 10.1038/s41443-025-01135-1

Ali Ünal, Ali Şahin, Mesut Altan, İhsan Batuhan Demir, İyimser Üre, Hazım Alparslan Mazlum, Lorenzo Cirigliano, Mirko Preto, Marco Falcone, Murat Gül

{"title":"Postoperative complication severity prediction in penile prosthesis implantation: a machine learning-based predictive modeling study.","authors":"Ali Ünal, Ali Şahin, Mesut Altan, İhsan Batuhan Demir, İyimser Üre, Hazım Alparslan Mazlum, Lorenzo Cirigliano, Mirko Preto, Marco Falcone, Murat Gül","doi":"10.1038/s41443-025-01135-1","DOIUrl":"https://doi.org/10.1038/s41443-025-01135-1","url":null,"abstract":"Prediction of postoperative complications is crucial in surgical care, particularly for penile prosthesis implantation. We retrospectively evaluated demographic, clinical, laboratory, and surgical data from patients who underwent penile prosthesis implantation between 2015 and 2023. Six machine learning algorithms-Gradient Boosting (GB), AdaBoost, Support Vector Machine (SVM), Random Forest (RF), XGBoost (XGB), and Naive Bayes (NB)-were trained to predict the occurrence and severity of postoperative complications. Model performance was assessed using accuracy, F1 score, sensitivity, specificity, Youden Index, and AUC value, and statistical comparisons identified the most effective approach. The GB model achieved the highest F1 score (0.86 ± 0.09; 95% CI, 0.84-0.87), significantly outperforming other models. Sensitivity was greatest for GB and XGB (0.78 ± 0.13; 95% CI, 0.75-0.80), with GB superior to AdaBoost and SVM (p < 0.001). RF demonstrated the highest specificity (1.00 ± 0.00; 95% CI, 1.00-1.00), exceeding AdaBoost, SVM, and NB (p < 0.001). GB best predicted mild complications (0.74 ± 0.14; 95% CI, 0.72-0.77), while NB excelled for severe complications (0.94 ± 0.17; 95% CI, 0.90-0.98). Overall accuracy was 0.90 ± 0.04 (95% CI, 0.89-0.90) for both GB and RF. Feature analysis highlighted HbA1c, total testosterone, and urea as key predictors. Implementing GB-based machine learning may enhance surgical decision-making in this setting.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of solid organ transplantation on sexual dysfunction and infertility in older men and women: A Claims Based Study. 实体器官移植对老年男性和女性性功能障碍和不育的影响：一项基于声明的研究。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-08 DOI: 10.1038/s41443-025-01127-1

Obinna Obuekwe, Haley Clark, Gal Saffati, Tatyana Yatsenko, Laura Oscar-Thompson, Carlos Riveros, Akhil Muthigi

{"title":"The impact of solid organ transplantation on sexual dysfunction and infertility in older men and women: A Claims Based Study.","authors":"Obinna Obuekwe, Haley Clark, Gal Saffati, Tatyana Yatsenko, Laura Oscar-Thompson, Carlos Riveros, Akhil Muthigi","doi":"10.1038/s41443-025-01127-1","DOIUrl":"https://doi.org/10.1038/s41443-025-01127-1","url":null,"abstract":"Solid organ transplantation (SOT) restores organ function and prolongs survival, but its impact on sexual dysfunction and infertility is underexplored. This study evaluated changes in their prevalence before and after transplantation across organ types. We conducted a retrospective cohort study using TriNetX, including 64 932 U.S. adults (≥18 years) who underwent heart, kidney, liver, lung, or pancreas transplants within the past 20 years. Sexual dysfunction (e.g., erectile dysfunction, dyspareunia) and infertility were identified using ICD-10 codes. Pre-post analysis assessed relative and absolute risk reduction (ARR). Analyses were stratified by sex and organ type. SOT was associated with reduced sexual dysfunction (ARR 1.40%, p < 0.001) and infertility (ARR 0.10%, p = 0.013). Males experienced a greater reduction in sexual dysfunction (ARR 2.11%, p < 0.001) than females (ARR 0.20%, p = 0.035). Sexual dysfunction declined following heart (ARR 2.21%, p = 0.001), kidney (ARR 1.42%, p < 0.001), lung (ARR 1.24%, p = 0.042), and liver (ARR 0.74%, p = 0.003) transplants. No difference was seen following pancreas transplantation, and infertility prevalence did not differ across SOT types. These findings suggest SOT may improve sexual health, particularly in men, though effects on infertility remain limited.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hard-flaccid syndrome: a systematic review of aetiopathophysiology, clinical presentation and management. 硬弛缓综合征：病理生理学，临床表现和管理的系统回顾。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-07 DOI: 10.1038/s41443-025-01118-2

Karl H Pang, Jiarong Feng, Yan Zhang

{"title":"Hard-flaccid syndrome: a systematic review of aetiopathophysiology, clinical presentation and management.","authors":"Karl H Pang, Jiarong Feng, Yan Zhang","doi":"10.1038/s41443-025-01118-2","DOIUrl":"https://doi.org/10.1038/s41443-025-01118-2","url":null,"abstract":"Hard-flaccid syndrome (HFS) is a rare condition characterised by a semi-rigid penis in the flaccid state, often accompanied by perineal and urinary symptoms. It may also induce psychological distress, which can exacerbate physical symptoms, creating a vicious cycle. There is currently no standardised treatment for HFS, and management typically focuses on addressing both the underlying causes and presenting symptoms. A systematic review of the literature identified 8 eligible studies. Although the exact aetiopathogenesis remains unclear, it is hypothesised that an initial penile trauma may trigger a cascade of neurovascular and inflammatory events. The associated psychological impact may further perpetuate symptoms, reinforcing the cycle of dysfunction. Common symptoms include perineal pain, urinary disturbances, and erectile and ejaculatory dysfunction. Evaluation involves a comprehensive clinical history, relevant blood and radiological investigations to exclude other pathologies, and the use of symptom questionnaires. Reported treatments include phosphodiesterase-5 inhibitors, anxiolytics, low-intensity shockwave therapy, pelvic floor physical therapy, spinal surgery, and biopsychosocial therapy. Management should be individualised, with a focus on relieving symptoms and breaking the self-perpetuating cycle of HFS. Further evidence-based studies are needed to better understand the pathophysiology of HFS, as well as to develop clear diagnostic criteria and management guidelines.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silicone penile prosthesis without suprapubic lipectomy for buried penis: a pilot study on the efficacy of Himplant^TM. 不切除耻骨上脂的硅胶阴茎假体治疗埋藏性阴茎：HimplantTM疗效的初步研究。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-04 DOI: 10.1038/s41443-025-01125-3

James Elist, Keon Amirazodi, Kambiz Tajkarimi, Adam De Fazio, Britney L Atwater, Steven K Wilson

{"title":"Silicone penile prosthesis without suprapubic lipectomy for buried penis: a pilot study on the efficacy of HimplantTM.","authors":"James Elist, Keon Amirazodi, Kambiz Tajkarimi, Adam De Fazio, Britney L Atwater, Steven K Wilson","doi":"10.1038/s41443-025-01125-3","DOIUrl":"https://doi.org/10.1038/s41443-025-01125-3","url":null,"abstract":"Adult acquired buried penis (AABP) is a condition where the penile shaft becomes concealed by surrounding tissues, often due to obesity, leading to significant physical and psychological distress. This pilot study evaluates the efficacy of HimplantTM (International Medical Devices Inc., Beverly Hills, CA, USA), a subcutaneous silicone penile prosthesis, for correcting AABP without concurrent manipulation of suprapubic fat. Twelve adult patients (mean age 39.1 ± 10.8 years) underwent HimplantTM insertion between January 2023 and May 2024. Standardized pre- and postoperative measurements showed a mean increase of 3.52 ± 0.41 cm in flaccid dorsal length and 2.78 ± 0.54 cm in midshaft girth (p < 0.0001). A non-validated follow-up questionnaire revealed that 85.7% of respondents (6/7) reported improved self-confidence in both daily life and sexual activity. The overall complication rate was low and limited to minor, conservatively managed issues; there were no penile infections, penile skin erosions, or other cases requiring implant removal. Notably, no recurrences of AABP were observed during a median follow-up period of 16.5 months. These findings suggest that HimplantTM may offer a safe, effective, and minimally invasive surgical solution for AABP, improving both functional outcomes and psychosocial well-being.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dimensions of sexual self-concept and sexual dysfunctions in middle-aged men: results of the Bavarian Men's Health-Study. 中年男性性自我概念维度与性功能障碍：巴伐利亚男性健康研究结果

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-04 DOI: 10.1038/s41443-025-01119-1

Valentin H Meissner, Victoria A Söhne, Andreas Dinkel, Matthias Jahnen, Stefan Schiele, Martina Kron, Jürgen E Gschwend, Kathleen Herkommer

{"title":"Dimensions of sexual self-concept and sexual dysfunctions in middle-aged men: results of the Bavarian Men's Health-Study.","authors":"Valentin H Meissner, Victoria A Söhne, Andreas Dinkel, Matthias Jahnen, Stefan Schiele, Martina Kron, Jürgen E Gschwend, Kathleen Herkommer","doi":"10.1038/s41443-025-01119-1","DOIUrl":"https://doi.org/10.1038/s41443-025-01119-1","url":null,"abstract":"Sexual self-concept is multidimensional and a key construct in understanding people's sexuality. The etiology as well as the relationship and causal direction between its different dimensions and sexual dysfunctions are not fully understood. A population-based cohort (N = 5665) of 50-year-old men completed questionnaires on dimensions of sexual self-concept (toughness, body image, sexual self-esteem, and perceived pressure with regard to sexuality) and sexual dysfunctions. Associations were assessed using multivariable linear regression analyses. Erectile dysfunction (ED), lifelong/acquired and subjective/variable premature ejaculation (PE), and low libido (LL) were associated with a more negative body image (p < 0.001), lower sexual self-esteem (p < 0.001), and higher perceived pressure with regard to sexuality (p < 0.001). ED, lifelong/acquired and subjective/variable PE were associated with toughness (p < 0.001), an association with LL could not be shown. A negative sexual self-concept was independently associated with sexual dysfunctions in middle-aged men highlighting that sexual self-concept represents a relevant factor in the biopsychosocial conception of sexual dysfunctions. The causal direction of this relationship needs to be determined in longitudinal studies.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

YouTube as a source of information on retrograde ejaculation: insights into content reliability. YouTube作为逆行射精的信息来源：对内容可靠性的洞察。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-02 DOI: 10.1038/s41443-025-01124-4

Abdullah Akdağ, Erhan Ateş, Çağatay Özsoy

{"title":"YouTube as a source of information on retrograde ejaculation: insights into content reliability.","authors":"Abdullah Akdağ, Erhan Ateş, Çağatay Özsoy","doi":"10.1038/s41443-025-01124-4","DOIUrl":"https://doi.org/10.1038/s41443-025-01124-4","url":null,"abstract":"This study evaluates the accuracy and reliability of YouTube videos on retrograde ejaculation, a condition affecting male fertility and quality of life. A systematic search conducted on December 11, 2024, identified 97 relevant videos from an initial pool of 545. Videos were analyzed using the DISCERN tool and Global Quality Score to assess reliability and educational quality. Reliable videos, comprising 54.6% of the sample, were significantly more often uploaded by universities, professional organizations, or nonprofit physician groups when compared to non-reliable videos (P = 0.006). When comparing different uploader subgroups, videos from universities, professional organizations, or nonprofit physician groups demonstrated significantly higher DISCERN and Global Quality Scores (P = 0.006, P < 0.001, respectively). In contrast, based on the overall distribution of uploader types among the entire video sample, videos uploaded by individuals or for-profit entities were more frequently classified as non-reliable (P = 0.005). Notably, viewership metrics did not differ significantly between reliable and nonreliable videos (P = 0.552), highlighting the challenge of discerning accurate content based on popularity alone. The findings underscore the importance of promoting high-quality, evidence-based information from credible sources on platforms like YouTube. Addressing misinformation and enhancing the visibility of reliable content are critical to improving patient education and decision-making in managing retrograde ejaculation.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Penile length preservation in penile prosthesis placement: tips & tricks. 阴茎假体放置中的阴茎长度保存：提示和技巧。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-02 DOI: 10.1038/s41443-025-01123-5

Pramod Krishnappa, Prasanna Matippa, Agustín Fraile-Poblador, Enrique Lledo-Garcia, Ignacio Moncada

{"title":"Penile length preservation in penile prosthesis placement: tips & tricks.","authors":"Pramod Krishnappa, Prasanna Matippa, Agustín Fraile-Poblador, Enrique Lledo-Garcia, Ignacio Moncada","doi":"10.1038/s41443-025-01123-5","DOIUrl":"https://doi.org/10.1038/s41443-025-01123-5","url":null,"abstract":"Penile Prosthesis (PP) is offered to patients with erectile dysfunction (ED) who prefer a definitive management, but subjective or objective penile length shortening after PP surgery is a concern. This review article aims to describe various preoperative, intraoperative and postoperative procedures and factors that may preserve or increase penile length during PP surgery. Preoperative strategies by the surgeon include vacuum erection devices (1 month), penile traction devices (2-4 months), and optimal surgical timing in priapism (early vs. delayed), and patient decisions include choosing a high-volume centre (>25 PP/year) and implant type (malleable vs. inflatable). The intraoperative manoeuvres included the subcoronal no-touch technique, cavernosal tissue-sparing dilatation, ventral phalloplasty, suspensory ligament release, suprapubic lipectomy, the sliding technique, the multiple-slit technique, and tunical expansion procedures. Simultaneous radical prostatectomy and PP surgery is gaining momentum to preserve the penile length in patients who have preexisting ED. Postoperative protocols included immediate postoperative inflation (60-80% inflated for 6 weeks), pump inflation protocol and the use of a vacuum device (without the ring, for 12 weeks). Using the above factors, the gain in penile length may range between 0.2 and 6.0 cm. The outcomes of these procedures are not universally reproducible at all centres.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ectopic Placement of Inflatable Penile Prosthesis Pump into the Mons Fat Pad for Patients with Difficulty Reaching Their Scrotum: A Case Series. 充气阴茎假体泵异位植入蒙斯脂肪垫治疗难以到达阴囊的患者：一个病例系列。

IF 2.8 3区医学

International Journal of Impotence Research Pub Date : 2025-07-02 DOI: 10.1038/s41443-025-01110-w

Lillian Lai, Kyle O'Hollaren, Michael Sessine, Aron Liaw

{"title":"Ectopic Placement of Inflatable Penile Prosthesis Pump into the Mons Fat Pad for Patients with Difficulty Reaching Their Scrotum: A Case Series.","authors":"Lillian Lai, Kyle O'Hollaren, Michael Sessine, Aron Liaw","doi":"10.1038/s41443-025-01110-w","DOIUrl":"https://doi.org/10.1038/s41443-025-01110-w","url":null,"abstract":"Inflatable penile prosthesis (IPP) implantation is a well-established treatment for patients with erectile dysfunction. However, patients with a large body habitus often struggle to manipulate a pump placed in the scrotum. Here, we describe a novel technique for placing the IPP pump in the mons fat pad to improve accessibility. This technique follows the traditional approach for cylinder and reservoir placement, but instead creates a subcutaneous pocket in the mons fat pad overlying the inguinal region, where the IPP pump is secured to the dermis to prevent migration. The tubing was tunneled through the initial incision and connected using the traditional approach. Three patients with a mean BMI of 37.0±5.2 underwent this technique at our institution, including one primary implantation and two revisions due to difficulty accessing a scrotal pump. At follow-up ranging from 4 to 16 months, all devices remained functional, and all patients reported easy pump accessibility. No infections, erosions, or other complications were observed. This novel ectopic placement of the IPP pump in the mons fat pad is safe, technically feasible, and offers an alternative for patients with.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144553445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0