International Journal of Impotence Research最新文献_第2页

Response to Comment on: Penile vibratory stimulation as rehabilitation of erectile function following nerve-sparing radical prostatectomy: a quantitative pilot study. 阴茎振动刺激作为保留神经的根治性前列腺切除术后勃起功能的康复：一项定量的初步研究。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-20 DOI: 10.1038/s41443-026-01251-6

Helene Reif Andersen, Alexander Bjørneboe Nolsøe, Emil Durukan, Peter Busch Østergren, Christian Fuglesang S Jensen, Jens Sønksen, Mikkel Fode

引用次数: 0

Comment on: The outcomes of inflatable penile prosthesis implantation in the context of genital gender affirming surgery in assigned female at birth patients: a comparative study between cis-male dacron modified and zephyr surgical implants 475 female to male penile prosthesis 评论：充气阴茎假体植入在生殖性别确认手术背景下的女性出生患者的结果：顺式男性涤纶改良和和风外科假体的比较研究475名女性和男性阴茎假体。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-20 DOI: 10.1038/s41443-026-01268-x

Maya Levy, Garry Lester Sergio Pigot

引用次数: 0

Sexual and urinary outcomes of minimally invasive surgical therapies for LUTS/BPH: a narrative review. 微创手术治疗LUTS/BPH的性和泌尿结局：叙述性回顾。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-20 DOI: 10.1038/s41443-026-01271-2

Ahmet Tevfik Albayrak, Muhammet Volkan Bulbul, Andre Rubez, Adriano Fregonesi, Ege Can Serefoglu

{"title":"Sexual and urinary outcomes of minimally invasive surgical therapies for LUTS/BPH: a narrative review.","authors":"Ahmet Tevfik Albayrak, Muhammet Volkan Bulbul, Andre Rubez, Adriano Fregonesi, Ege Can Serefoglu","doi":"10.1038/s41443-026-01271-2","DOIUrl":"https://doi.org/10.1038/s41443-026-01271-2","url":null,"abstract":"Benign prostatic hyperplasia (BPH) is a major cause of lower urinary tract symptoms (LUTS) and is frequently associated with erectile and ejaculatory dysfunction. Although transurethral resection of the prostate (TURP) remains an effective treatment for symptom relief, its negative impact on sexual function has driven increasing interest in minimally invasive surgical therapies (MISTs) that aim to preserve sexual outcomes. This narrative review summarizes contemporary evidence on urinary and sexual outcomes following major MISTs, including iTIND™, UroLift™, Rezum™, Aquablation, transperineal laser ablation (TPLA), prostatic artery embolization (PAE), and the drug-coated balloon system Optilume BPH™. Across studies, most modalities demonstrated reductions in the International Prostate Symptom Score of 7.8-17 points and improvements in maximum urinary flow rate of 3-12 mL/s, though the magnitude of effect and durability varied. UroLift™ and TPLA consistently demonstrated strong ejaculation-sparing effects, owing to their non-ablative or highly selective mechanisms. Rezum™ and Aquablation provided durable symptom relief with low rates of de novo erectile dysfunction and mostly transient ejaculatory changes. PAE offered excellent sexual preservation but comparatively less pronounced urinary improvements. Early data on Optilume BPH™ suggest sustained LUTS/BPH improvement with reliable maintenance of sexual function. MISTs represent established alternatives to TURP; however, given heterogeneity in study populations, follow-up durations, and outcome definitions, conclusions should be interpreted cautiously.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electronic cigarettes, endothelial dysfunction, and erectile health: an emerging sexual medicine concern. 电子烟、内皮功能障碍和勃起健康：一个新兴的性医学问题。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-20 DOI: 10.1038/s41443-026-01275-y

Jarrett Noakes, Tate Valerio, Lucas Biondi, Marshall Daffner, Syed Sarwar, Alexander K Bishop, James T Burns, Rosstin Afsahi

引用次数: 0

Penile vibratory stimulation as rehabilitation of erectile function following nerve-sparing radical prostatectomy: A quantitative pilot study. 阴茎振动刺激作为保留神经的根治性前列腺切除术后勃起功能的康复：一项定量的初步研究。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-14 DOI: 10.1038/s41443-025-01185-5

Helene Reif Andersen, Alexander Bjørneboe Nolsøe, Emil Durukan, Peter Busch Østergren, Christian Fuglesang S Jensen, Jens Sønksen, Mikkel Fode

{"title":"Penile vibratory stimulation as rehabilitation of erectile function following nerve-sparing radical prostatectomy: A quantitative pilot study.","authors":"Helene Reif Andersen, Alexander Bjørneboe Nolsøe, Emil Durukan, Peter Busch Østergren, Christian Fuglesang S Jensen, Jens Sønksen, Mikkel Fode","doi":"10.1038/s41443-025-01185-5","DOIUrl":"10.1038/s41443-025-01185-5","url":null,"abstract":"Penile vibratory stimulation (PVS) has shown promise in aiding recovery of erectile function after radical prostatectomy. This prospective cohort pilot study aimed to determine optimized settings in preparation of a randomized controlled trial to further asses its effects. Men without prior erectile dysfunction were instructed to use a mechanical medical vibrator daily for six months following surgery and to adjust settings according to preferences. The primary objective was the optimized parameters defined by the time spent using the vibrator, along with the most frequently used amplitude and frequency settings. Secondary outcomes included patient acceptance and settings most often inducing erections and orgasms. Twenty men were included, 19 of whom used the device on a median of 40.1% of days (IQR: 28,8-51,4%). PVS was most often performed for 5 min (IQR: 5-10 min) and the most frequently used amplitude and frequency were 1 mm and 90 Hz. These parameters were also the ones to induce erections and orgasms most often. At 6 months, 12/19 men were able to engage in penetrative sex. Fourteen patients reported satisfaction with the device, and no adverse effects were observed. Altogether, patient-optimized parameters consisting of 5 min daily stimulation at an amplitude of 1 mm and a frequency of 90 Hz were the most used and showed the strongest association with both erections and orgasms. These parameters will be used in a larger randomized trial.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Non-obstetric female genital tract trauma requiring surgical intervention: A 15-year retrospective cohort analysis. 需要手术干预的非产科女性生殖道创伤：一项15年回顾性队列分析。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-14 DOI: 10.1038/s41443-026-01267-y

Inshirah Sgayer, Mona Kuzli, Olga Braude, Salit Edwards, Lior Lowenstein, Maya Frank Wolf

{"title":"Non-obstetric female genital tract trauma requiring surgical intervention: A 15-year retrospective cohort analysis.","authors":"Inshirah Sgayer, Mona Kuzli, Olga Braude, Salit Edwards, Lior Lowenstein, Maya Frank Wolf","doi":"10.1038/s41443-026-01267-y","DOIUrl":"https://doi.org/10.1038/s41443-026-01267-y","url":null,"abstract":"Non-obstetric genital tract injuries, though uncommon, can result in significant morbidity. This 15-year retrospective single-centre cohort study included 42 women who underwent surgical intervention for non-obstetric genital injuries at a tertiary center. Consensual sexual activity accounted for 85.7% of cases, and most of these occurred during first intercourse (80.9%). All the intercourse-related injuries were reported as consensual. Vaginal injuries comprised 78.6%; the median tear length was 2 cm. A hemoglobin drop of ≥2 g/dL was observed in 40.0%. For women with sex-related compared to trauma-related injuries, the median age was younger (26.5 vs. 49.0 years, p = 0.045) and the median parity lower (0 vs. 3.5, p = 0.003). The vagina was more often involved in sex-related than trauma-related injuries (83.3 vs. 50.0%, p = 0.065), and the vulvar less often (16.7 vs. 50.0%, p = 0.065). Arab women were generally younger, less frequently postmenopausal, and more often presented with a partner compared with Jewish women. Among sex-related injuries, Arab women more commonly sustained combined vaginal and vulvar injuries, whereas Jewish women presented predominantly with vaginal injuries. The findings highlight the potential importance of trauma-informed, culturally sensitive, and individualized clinical care. However, they should be interpreted with caution given the retrospective design and relatively small sample size.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Soft glans after penile prosthesis surgery: a patient-reported study of prevalence and clinical impact. 阴茎假体手术后软龟头：一项患者报告的患病率和临床影响研究。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-13 DOI: 10.1038/s41443-026-01263-2

Sarah Michael, Jack Hay, Evan Maher, Fereshteh Zarnani, Ayman Haider, Vaibhav Modgil, Ian Pearce, Peter Grice

{"title":"Soft glans after penile prosthesis surgery: a patient-reported study of prevalence and clinical impact.","authors":"Sarah Michael, Jack Hay, Evan Maher, Fereshteh Zarnani, Ayman Haider, Vaibhav Modgil, Ian Pearce, Peter Grice","doi":"10.1038/s41443-026-01263-2","DOIUrl":"https://doi.org/10.1038/s41443-026-01263-2","url":null,"abstract":"Soft glans syndrome, defined as inadequate glans engorgement despite full prosthesis inflation or adequate placement of a malleable implant, is a poorly studied source of dissatisfaction after penile prosthesis surgery, with prevalence often considered low or unknown. We conducted a cross-sectional patient survey of men who underwent penile prosthesis implantation at a tertiary centre between December 2023 and May 2025. The survey addressed glans engorgement, sexual satisfaction, ejaculatory function, cosmetic perception, and treatment interest. Associations were analysed using chi-square tests and univariable logistic regression. Eighty men participated (mean age 59.7 years (SD 9.3), median erectile dysfunction duration of 36 months (IQR 48). Soft glans was reported by 63.3% (n = 50/79), with another 17.7% (n = 14/79) experiencing it half the time or less. Most respondents (79%,n = 62/79) expressed interest in treatment. Soft glans was significantly associated with impaired ejaculatory function (p = 0.019), reduced sexual enjoyment (p < 0.001), and treatment interest (p < 0.001). Older age increased risk (OR 1.07, 95% CI 1.01-1.13, p = 0.014), while BMI, comorbidities, implant type, surgeon seniority, indication, and cosmetic satisfaction showed no association. Based on our single-center cohort analysis, soft glans appears to be a relatively common finding following penile prosthesis surgery. It has important functional and psychosocial consequences, underscoring the need for preoperative counselling and the development of targeted management strategies.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147672970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Glanspexy for real glans hypermobility after penile prosthesis surgery: a retrospective review and patient satisfaction analysis. 阴茎假体手术后真正的龟头过度活动的glanspxy：回顾性回顾和患者满意度分析。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-10 DOI: 10.1038/s41443-026-01252-5

Isabel Dighero, Mohammed Shah, Wai Gin Lee, Angelo di Giovanni, David Ralph, Marta Skrodzka

{"title":"Glanspexy for real glans hypermobility after penile prosthesis surgery: a retrospective review and patient satisfaction analysis.","authors":"Isabel Dighero, Mohammed Shah, Wai Gin Lee, Angelo di Giovanni, David Ralph, Marta Skrodzka","doi":"10.1038/s41443-026-01252-5","DOIUrl":"https://doi.org/10.1038/s41443-026-01252-5","url":null,"abstract":"Glans hypermobility is a rare complication of penile implant surgery. There is a paucity of available literature on glanspexy treatment as a definitive solution and patients' post-operative satisfaction. We conducted a retrospective review of patients who underwent glanspexy for real glans hypermobility (RGH) following penile implant insertion at a quaternary referral centre in 2012-2024. Demographic features, surgical techniques and post-operative outcomes were logged. We contacted patients via telephone to conduct a modified Erectile Dysfunction Inventory of Treatment Satisfaction questionnaire. Out of 3210 patients who underwent penile prosthesis insertion from 2012-2024, 40 underwent glanspexy. Glanspexy was performed at the time of primary implantation in 22.5% patients and as a secondary procedure in 77.5%. 67.65% of patients were satisfied and 77.78% felt erection shape was better post glanspexy. 76.47% felt the treatment met their expectations. 94.12% of patients agreed they would still choose to undergo the surgery again. Glanspexy done as a secondary procedure, in comorbid patients, after multiple implant revisions or genital/pelvic surgeries results in lower satisfaction. For the small cohort who experience RGH, glanspexy represents a unique opportunity to achieve restorative function of their penile prosthesis with satisfactory outcomes.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147654103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing cylinder selection in inflatable penile prosthesis surgery: a narrative review. 充气阴茎假体手术中圆柱体选择的优化：叙述性回顾。

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-09 DOI: 10.1038/s41443-026-01259-y

Yi-Kai Chang, Nicholas Gillman, Eric Chung

{"title":"Optimizing cylinder selection in inflatable penile prosthesis surgery: a narrative review.","authors":"Yi-Kai Chang, Nicholas Gillman, Eric Chung","doi":"10.1038/s41443-026-01259-y","DOIUrl":"https://doi.org/10.1038/s41443-026-01259-y","url":null,"abstract":"There have been considerable advances in our scientific knowledge, surgical techniques and technological innovation for modern inflatable penile prosthesis (IPP) implants over the past 50 years. Four major device companies have successfully manufactured and marketed IPP devices worldwide, and these devices have pre-determined cylinder sizes and unique properties. It is recommended that the cavernosal body be dilated to at least 12 mm to accommodate a standard IPP cylinder and 10 mm for smaller diameter or narrow-base devices. The selection of cylinder size and type is often based on intraoperative total corporal length and dilation measurements; however, other factors such as the surgeon's expertise and preference, the presence of corporal fibrosis and/or the use of a rear-tip extender can influence the final cylinder selection. A properly sized cylinder that sits nicely within the corporal body and cycles well is the prerequisite for an optimal IPP function and a satisfied patient. This article provides a narrative review of the overview of the decision-making and common surgical challenges encountered in the selection of cylinder size and type.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

From fibrosis to restoration: the multimodal 3 Ts protocol for Peyronie's disease. 从纤维化到恢复：Peyronie病的多模态3ts方案

IF 2.5 3区医学

International Journal of Impotence Research Pub Date : 2026-04-09 DOI: 10.1038/s41443-026-01262-3

Dimitrios Hatzichristou

{"title":"From fibrosis to restoration: the multimodal 3 Ts protocol for Peyronie's disease.","authors":"Dimitrios Hatzichristou","doi":"10.1038/s41443-026-01262-3","DOIUrl":"https://doi.org/10.1038/s41443-026-01262-3","url":null,"abstract":"Traditional management strategies for Peyronie's disease, largely monotherapeutic and stage-dependent, have produced inconsistent outcomes and rarely address the underlying biology of fibrosis. Based on existing knowledge, a multimodal novel concept, the 3Ts Protocol, is presented, involving Tadalafil daily, Tunneling with intralesional biologics, and daily Traction therapy. It introduces a comprehensive, regenerative strategy that integrates pharmacologic, biologic, and mechanical interventions in a single sequence. Daily low-dose tadalafil improves cavernosal oxygenation and arterial inflow, counteracting hypoxia-driven fibrosis. Tunneling injections of biologics deliver growth factors directly into and around the plaque, promoting regeneration and remodeling, while traction therapy provides continuous mechanotransductive stimulation for structural realignment. Together, these components act synergistically to modulate inflammation, restore microvascular perfusion, and induce tissue regeneration. Importantly, this work provides, to our knowledge, the first fully specified, step-by-step description of a Peyronie's disease management protocol, enabling reproducible clinical implementation and facilitating meaningful comparison across future studies employing different biologic agents. Prospective randomized studies examining the efficacy of the 3Ts Protocol are needed. If so, the 3Ts Protocol represents a paradigm shift from deformity correction to structural restoration, offering a novel pathway toward multimodal management of Peyronie's disease.","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0