International Journal of Medicinal and Aromatic Plants最新文献_第7页

Appraisal of Antiophidian Properties of Cardiospermum halicacabum L. Leaf and Callus Extracts against Naja Naja Venom 心芹叶及愈伤组织提取物抗蛇毒作用的研究

International Journal of Medicinal and Aromatic Plants Pub Date : 2021-01-01 DOI: 10.35248/2167-0412.21.10.399

H. V. Girish, A. Nataraju, R. Rajaiah, Vishwanath Bs, M. Sudarshana, N. Reshi

{"title":"Appraisal of Antiophidian Properties of Cardiospermum halicacabum L. Leaf and Callus Extracts against Naja Naja Venom","authors":"H. V. Girish, A. Nataraju, R. Rajaiah, Vishwanath Bs, M. Sudarshana, N. Reshi","doi":"10.35248/2167-0412.21.10.399","DOIUrl":"https://doi.org/10.35248/2167-0412.21.10.399","url":null,"abstract":"Considering the limitations of antivenom therapy towards toxicity following envenomation, investigators are probing for effective phytochemicals with promising antivenom effects. In the current study, Cardiospermum halicacabum leaf and callus methanol extracts were investigated for their ability to neutralize Indian cobra (Najanaja) venom. Soxhlet extraction using methanol was performed since leaf and callus extracts demonstrated significant neutralization of N. najavemon in preliminary studies. In vitro neutralizing potential of both extracts were evaluated against phospholipase A2, preoteases and hyaluronidases. In addition, alleviation of N. naja-induced characteristic edema inducing activity, myotoxicity and coagulation, hemolytic activity were performed in mouse models and human blood samples. Leaf and callus methanol extract contained high concentrations of phenols, alkaloids, steroids and saponins and demonstrated significant in vitro inhibition of N. naja PLA2, proteases and hyaluronidase activities at 30-40 µg concentrations. Significant neutralization of N. naja-induced indirect hemolysis, edema, anticoagulant effect and myotoxicity was attained using both extracts. Overall leaf and callus extracts (1mg/kg) postponed animal survival by 33 ± 9.3 and 50 ± 12.4 mins, respectively. C. halicacabum leaf and callus methanol extracts demonstrated significant neutralization of N. naja enzymes that contribute to grievous effects on various tissues/organs. The study scientifically supports the anecdotal use of C. halicacabum in complementary medicine and demonstrates that callus extract is more potent antidote than leaf. Further, callus extract is a potent candidate for isolation of phytochemicals towards management of snakebite.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"11 12","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91440730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front matter 前页

International Journal of Medicinal and Aromatic Plants Pub Date : 2021-01-01 DOI: 10.1016/b978-0-12-819590-1.00016-1

引用次数: 0

Ethno-Medicinal Plant Species Used For Animal and Insect Bite (Sting) of Vijayapur (Bijapur) District of Karnataka, India 印度卡纳塔克邦Vijayapur (Bijapur)地区用于动物和昆虫叮咬(刺痛)的民族药用植物物种

International Journal of Medicinal and Aromatic Plants Pub Date : 2021-01-01 DOI: 10.35248/2167-0412.21.10.408

Arati Laddimath

引用次数: 1

Bioactivity of Rosmarinus officinalis Extracts in Combination with Camelus dromedarius Whey Proteins 迷迭香提取物与骆驼乳清蛋白配用的生物活性研究

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.22223

L. Abdallah, N. Jarrar, A. Abu-Hijleh

{"title":"Bioactivity of Rosmarinus officinalis Extracts in Combination with Camelus dromedarius Whey Proteins","authors":"L. Abdallah, N. Jarrar, A. Abu-Hijleh","doi":"10.48347/IMIST.PRSM/AJMAP-V6I3.22223","DOIUrl":"https://doi.org/10.48347/IMIST.PRSM/AJMAP-V6I3.22223","url":null,"abstract":"The present study was performed to evaluate the antibacterial potential of camel whey and Rosmarinus officinalis aqueous and ethanol extracts as well as their effect on glutathione-S- transferases (GSTs) enzymes activity. The antibacterial activity of all samples and combinations was tested against Staphylococcus aureus and Escherichia coli using micro-broth dilution method. In addition to that, the effect of camel whey and plant extracts on GSTs was studied by spectrophotometric method using 1-chloro-2,4-dinitro-benzene (CDNB) as substrate. The obtained results showed that ethanol extract was the most effective when compared to the aqueous extract and whey proteins. Synergistic antibacterial activity was observed for whey and ethanol extract against E. coli with MBC value equal to 0.39 mg/ml. In contrast, whey combination to aqueous extract showed antagonistic bacteriostatic and bactericidal effect against both bacteria. Moreover, results revealed that all samples with 1 mg/ml concentration increased the activity of GSTs in vitro . The recorded GSTs activity was higher after combination of whey to both extracts. The best results obtained after combining the ethanol extract to whey proteins. The obtained results provided the necessity for further bioactivity studies between active ingredients of both camel whey and plant extracts.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"1 1","pages":"20-36"},"PeriodicalIF":0.0,"publicationDate":"2020-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87335010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-bacterial activity of methanolic extracts of the aerial parts of Inulaviscosa l., from Guelma (Algeria) 阿尔及利亚圭尔马菊地上部甲醇提取物的抑菌活性

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.23653

K. Ounaissia, A. Nassar, Bouthaina Soltani, S. Bennadja, A. Djahoudi

{"title":"Anti-bacterial activity of methanolic extracts of the aerial parts of Inulaviscosa l., from Guelma (Algeria)","authors":"K. Ounaissia, A. Nassar, Bouthaina Soltani, S. Bennadja, A. Djahoudi","doi":"10.48347/IMIST.PRSM/AJMAP-V6I3.23653","DOIUrl":"https://doi.org/10.48347/IMIST.PRSM/AJMAP-V6I3.23653","url":null,"abstract":"The objective assigned to the present study isthe evaluation of the antibacterialactivity of the methanolic extracts of the aerial parts of Inulaviscosa L. The antibacterial activity of the extracts is carried out by the diffusion method on agar medium vis-a-vis twenty three bacterial strains, chosen according to the traditional use of this species in Algeria: Bacillus cereus, Escherichia coli (ATCC22), Escherichia coli (BLSE), Escherichia coli (ciproR), Escherichia coli (mcr1), Klebsiellapneumoniae (C+), Klebsiellapneumoniae (C-), Klebsiellapneumoniae Nassey Marseille, Serratiasp, Salmonella sp, Pseudomonasaeruginosa (ATCC53), Pseudomonas sp, Pseudomonas aeruginosa (VIM21), Pseudomonas aeruginosa (VIM22), Acinetobacter (NDM1), Acinetobacter (OXA23), Staphylococcus aureus, Staphylococcus aureus (23), Staphylococcus aureus (13), Enterobacter cloacae (FOSR1), Enterobacter cloacae (FOSR2), Enterococcus faecalis (Vanc R), Enterococcus faecalis (ATCC12). Pseudomonas aeruginosa (ATCC53) was the most sensitive species followed by Pseudomonas sp . significant sensitivity was observed for the Klebsiellapneumoniae isolated in Marseille. However, Staphylococcus aureus was the most resistant to the extracts tested.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"57 1","pages":"10-19"},"PeriodicalIF":0.0,"publicationDate":"2020-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76926081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Antioxidants activity and cholesterol regulation effect of Caralluma flava N.E.Br extract in HepG2 cells 芥黄N.E.Br提取物对HepG2细胞抗氧化活性及胆固醇调节作用

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.23655

G. Al-Naqeb

{"title":"Antioxidants activity and cholesterol regulation effect of Caralluma flava N.E.Br extract in HepG2 cells","authors":"G. Al-Naqeb","doi":"10.48347/IMIST.PRSM/AJMAP-V6I3.23655","DOIUrl":"https://doi.org/10.48347/IMIST.PRSM/AJMAP-V6I3.23655","url":null,"abstract":"Herbal medicine has a long-standing history in many locations in Yemen and continue to provide useful and applicable tools for treating ailments. The objectives of the present study are to investigate antioxidant activity and cholesterol regulatory effect of Caralluma flava N.E.Br methanolic extract (CFM) through chemical and molecular approaches. CFM afforded the yield of 18 % (w/w) through methanolic extraction and contained considerable amount of phenolic and flavonoid compounds (9.22 ± 1.4 mg/g) and 3.35 ± 0.16 mg/g respectively). Antioxidant activity assays revealed that CFM are effective antioxidant with 76.8% DPPH scavenging activity bleaching inhibitory activity. Result from s-carotene–linoleic acid assay shows that CFM efficiently retarded the oxidation of linoleic acid in the reaction system compared to control. CFM regulate the expression of cholesterol metabolism genes in HepG2 cells in a dose-dependent manner. The low-density lipoprotein receptor (LDLR) mRNA level was significantly up-regulated by 1.3, 2.4 and 3.2 fold compared to control cells. The mRNA level of 3-Hydroxy-3-Methylglutaryl-CoA Reductase (HMGCOA) was significantly suppressed by 12, 30 and 50% in a dose dependent manner compared to the control cells treated with 20, 50 and 100 µg/ml of CFM respectively. Apolipoprotein A-1 (Apo A-1) gene was up-regulated by 1.7 and 2.2 fold and apolipoprotein B100 (Apo B100) gene was suppressed by 11% and 24% in HepG2 cells treated with 50 and 100 µg/ml of CFM respectively, compared to control cells. In conclusion, CFM is a potential cardioprotector through enhancement of cholesterol regulation and exertion of antioxidant activity.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"1 1","pages":"57-75"},"PeriodicalIF":0.0,"publicationDate":"2020-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89167134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antimycobacterial Activity and Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Henna (Lawsonia Inermis) Leaves extract. 指甲花叶提取物抑菌活性及气相色谱-质谱联用分析。

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.22340

A. M. Abdelrahman, Khalid Eltahir Khalid Kheiralla, N. Ibrahim, A. Elegail, You-ning Ma, E. Ahmed

{"title":"Antimycobacterial Activity and Gas Chromatography-Mass Spectrometry (GC-MS) Analysis of Henna (Lawsonia Inermis) Leaves extract.","authors":"A. M. Abdelrahman, Khalid Eltahir Khalid Kheiralla, N. Ibrahim, A. Elegail, You-ning Ma, E. Ahmed","doi":"10.48347/IMIST.PRSM/AJMAP-V6I3.22340","DOIUrl":"https://doi.org/10.48347/IMIST.PRSM/AJMAP-V6I3.22340","url":null,"abstract":"Lawsonia inermis or (henna) is used as a cosmetic dye and medicinal plant for its strong antimycobacterial and other therapeutic effects. In this study, we investigated the phytochemical and antimycobacterial activity of L. inermis leaves methanol extract against Rifampicin sensitive and resistant mycobacterium tuberculosis ( M.tb ) strains. Fresh Sudanese henna leaves were collected from the University of Gezira campus garden, shade dried, ground and was extracted by methanol. Crude henna methanolic extract was then tested for antimycobacterial activity against eight M.tb strains sensitive and resistant to rifampicin, using drug susceptibility test. The phytoconstituents were identified by using gas chromatograph interfaced to a mass spectrometer (GC-MS). GC-MS analysis revealed the presence of seven phytochemical components, with prevailing of squalene (34.433%), Lawsone (20.185%) and Coumarin-4-carboxylic acid (23.328%). The crude methanolic extract of henna leaves demonstrated an inhibitory effect on all tested M.tb strains, with antimycobacterial activity being ≤ 50 mg/ml. Henna leaves crude methanolic extract is rich in phytoconstituents that may involve in its remarkable antimycobacterial activity against rifampicin sensitive and resistant M.tb strains.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"89 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2020-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82682970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Potential use of Eastern Hararghe Ethiopia medicinal plants for COVID-19- like symptoms: A review 埃塞俄比亚哈拉尔河东部药用植物治疗COVID-19样症状的潜在用途:综述

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.22976

Teshome Gonfa Hordofa, Tsegu Kiros

{"title":"Potential use of Eastern Hararghe Ethiopia medicinal plants for COVID-19- like symptoms: A review","authors":"Teshome Gonfa Hordofa, Tsegu Kiros","doi":"10.48347/IMIST.PRSM/AJMAP-V6I3.22976","DOIUrl":"https://doi.org/10.48347/IMIST.PRSM/AJMAP-V6I3.22976","url":null,"abstract":"The world is in a great war with the rapidly and exponentially spreading virus, the corona virus disease (COVID-19). To win this pandemic, pharmaceutical companies and scientists are in a tight race to get modern vaccines or drugs. Following such efforts, dexamethasone (one of the known corticosteroids) has shown hopeful potency against the pandemic corona virus disease (COVID-19) as per the WHO updated report. However, till the development of this review study, no single anti-COVID-19 drug/or vaccine has fully been announced yet. Hence, for a time being, the world has been forced to turn its face towards alternative phyto-medicines. Accordingly, scholars by now have recommended plant lead traditional medicines as first aid kits to minimize the impact of corona virus pandemic. In this review paper, an attempt is made to introduce some selected possible antiviral medicinal plants found in the Eastern Hararghe region of Ethiopia. We focused on those plant species which have routinely been used by the local community to treat infectious diseases such as flu, cold, cough, sore throat, headache, pneumonia, lung abscess, fever, malaria, asthma and related viral infections. A total of 33 plant species from different families (Fabaceae is the dominant one, 18.18%) were reviewed. Since the above mentioned infections are symptomatically similar to that of COVID-19, the plant species reviewed in the present paper may have a potential to treat and control the surging corona virus pandemic. This review may therefore provide useful information about the antiviral therapeutic uses of most preferred medicinal plants of Eastern Hararghe, Ethiopia. The present review may serve as an input to the research and development of antiviral agents in the future.","PeriodicalId":14019,"journal":{"name":"International Journal of Medicinal and Aromatic Plants","volume":"48 1","pages":"76-115"},"PeriodicalIF":0.0,"publicationDate":"2020-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78765096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Chemical constituents of the pine extracts and their activities: A review 松树提取物的化学成分及其活性研究进展

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-11-16 DOI: 10.48347/IMIST.PRSM/AJMAP-V6I3.23652

M. Ayaria, M. Romdhanea

引用次数: 3

Biosynthesis of Lemongrass Essential Oil and the Underlying Mechanism for Its Insecticidal Activity 柠檬草精油的生物合成及其杀虫作用机制研究

International Journal of Medicinal and Aromatic Plants Pub Date : 2020-09-13 DOI: 10.1007/978-3-030-58975-2_18

M. Mukarram, M. A. A. Khan, Andleeb Zehra, Sadaf Choudhary, T. Aftab, M. Naeem

引用次数: 7