International Journal of Dentistry最新文献

{"title":"Synovial Matrix Remodeling and Inflammatory Profile in Disc Displacement of the Temporomandibular Joint: An Observational Case-Control Study.","authors":"Pallavi Khattar, Mattias Ulmner, Henrike Häbel, Bodil Lund, Rachael V Sugars","doi":"10.1155/2024/2450066","DOIUrl":"https://doi.org/10.1155/2024/2450066","url":null,"abstract":"<p><p><b>Background:</b> Pain-related temporomandibular joint disorders (TMJD) are a major public health problem, including the diagnoses of disc displacement (DD) with and without reduction (DDwR/DDwoR). <b>Objectives:</b> The study aimed to examine the matrix remodeling and the inflammatory profile in synovial tissues of patients with TMJ-DD, with a view to understand the pathophysiology, and to contribute to the development of tissue-based diagnostic criteria. <b>Methods:</b> This laboratory-based observational case-control study included 30 synovial tissue samples obtained from 30 patients, diagnosed with delayed (DO) or sudden (SO) onset of DDwoR, which were compared against the reference patient material, DDwR (<i>n</i> = 10/diagnosis group). Tissue samples were investigated histologically and via quantitative immunohistochemistry for a panel of antibodies targeted against extracellular matrix proteins and inflammatory markers. The data were analyzed using a generalized linear model with a gamma family distribution (<i>p</i> < 0.05). <b>Results:</b> Quantification of immunostaining revealed significant differences in the distribution of collagen type III (DO, <i>p</i> < 0.001), lumican (DO, <i>p</i> < 0.05), matrix metalloproteinase-2 (DO, <i>p</i> < 0.05), CD4 T-helper cells (DO, <i>p</i> < 0.01; SO, <i>p</i> < 0.001), and CD68 monocytic immune cells (both SO and DO, <i>p</i> < 0.001) in DDwoR groups compared to the reference patient material, DDwR. <b>Conclusions:</b> The observations confirmed differences in matrix remodeling and an increase in local inflammatory activity in the DDwoR diagnosis compared to the reference patient material, DDwR. The study highlighted the importance of synovial tissue characterization to unite micropathology and clinical findings, leading to more reliable diagnostic tools.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"2450066"},"PeriodicalIF":1.9,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11424871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Designing Entrustable Professional Activities for Treatment Planning of Oral Cancer by Maxillofacial Surgery Residents: A Modified Delphi Study.","authors":"Maidah Hanif, Yawar Hayat Khan, Kamran Ali","doi":"10.1155/2024/5516332","DOIUrl":"10.1155/2024/5516332","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to develop a competency framework based on entrustable professional activities (EPAs) in oral cancer management by postgraduate trainees in oral and maxillofacial surgery through expert consensus.</p><p><strong>Materials and methods: </strong>The study design was based on a modified Delphi technique and involved iterative online surveys with two rounds of data collection and analysis. Initial development of the questionnaire identified five EPAs based on 42 competencies along with supervision level and assessment strategies. The first Delphi round involved administration of the survey questionnaire online to maxillofacial surgeons meeting the inclusion criteria for experts. Consensus was achieved on five EPAs and 36 competencies (≥80% response rate). Six competencies were rephrased and sent again in the Round 2 questionnaire to achieve a consensus.</p><p><strong>Results: </strong>A total of 45 experts participated in Round 1 followed by input from 27 experts in Round 2 of the Delphi panel. Following two iterative rounds of online surveys and feedback, expert consensus was achieved to develop an EPA framework in five EPA domains focused on the management of oral cancer by postgraduate trainees in maxillofacial surgery including 38 specific competencies, supervision level, and assessment strategies. High content validity of the study was established through a comprehensive literature search, and expert feedback was evidenced by an excellent response rate (93.34%, and 64.28%) and a stringent criteria of response agreement amongst experts (≥80%).</p><p><strong>Conclusion: </strong>In conclusion, this study employed expert consensus to identify five EPAs with 38 competencies along with the required supervision level of postgraduate maxillofacial trainees for the management of oral cancer. This EPA framework provides a roadmap for training supervisors to map the learning outcomes in oral oncology for postgraduate trainees in oral and maxillofacial surgery.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"5516332"},"PeriodicalIF":1.9,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11416168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of Trigeminal Ganglion Neurons Innervating the Temporomandibular Joint in Chronic Pain Rat Model.","authors":"Wen Liu, Henghua Jiang, Jin Ke, Xin Liu, Yaping Feng, Jinsong Hou, Xing Long","doi":"10.1155/2024/7015382","DOIUrl":"10.1155/2024/7015382","url":null,"abstract":"<p><p><b>Background:</b> Phenotype alterations of nociceptive neurons have been shown to be a key step in the pathogenesis of many pain-related diseases. However, it is unclear if the characteristic changes of temporomandibular joint (TMJ) primary afferent neurons are related to the pathogenesis of temporomandibular joint osteoarthritis (TMJOA) chronic pain. This study aimed to determine the morphological and neurochemical changes in trigeminal ganglion (TG) neurons innervating the TMJ in TMJOA chronic pain rats. <b>Materials and Methods:</b> Monosodium iodoacetate (MIA)-induced TMJOA chronic pain rat model was established (<i>n</i> = 6), and saline was injected in rats of the control group (<i>n</i> = 6). TMJ primary afferent neurons were labeled with retrograde tracing (Dil). The spatial distribution and the expression of calcitonin gene-related peptide (CGRP), isolectin B4 (IB4), and neurofilament 200 (NF200) of TMJ primary afferent neurons in TG were investigated using immunofluorescence. Intracellular calcium signaling was recorded by calcium imaging (<i>n</i> = 20). <b>Results:</b> TMJ primary afferent neurons were located only in the V3 region of the TG from both saline- and MIA-injected rats. The number of TG neurons innervating the TMJ was increased in MIA-injected rats. Elevated number and intracellular calcium concentration of small- and medium-sized instead of large-sized Dil+ TG neurons were found in MIA-injected rats. The upregulated expression of CGRP and IB4, but not NF200, in TG neurons innervating the rat TMJs was accompanied by TMJOA chronic pain. <b>Conclusion:</b> This study suggests that sensitization of small- to medium-sized Dil+ TG neurons and CGRP- and IB4-positive Dil+ TG neurons might contribute to the development of TMJOA chronic pain in rats. This will provide valuable information for more efficient control of TMJOA chronic pain.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"7015382"},"PeriodicalIF":1.9,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415243/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neurological Complications following Surgical Treatments of the Lower Molars.","authors":"Antonio Mancini, Angelo Michele Inchingolo, Marco Di Blasio, Elisabetta de Ruvo, Angela Di Noia, Laura Ferrante, Gaetano Del Vecchio, Andrea Palermo, Francesco Inchingolo, Alessio Danilo Inchingolo, Gianna Dipalma","doi":"10.1155/2024/5415597","DOIUrl":"https://doi.org/10.1155/2024/5415597","url":null,"abstract":"<p><strong>Aim: </strong>The current review aims to explore postoperative neurological complications in third molar extractive surgery.</p><p><strong>Materials and methods: </strong>The PRISMA protocols were followed when conducting this review. We found a total of 2,250 articles that matched our topic using the Boolean keywords, mandibular nerve complications AND oral surgery, from PubMed (1,083), Scopus (435), and Web of Science (732), with the filters of English language articles, time range January 1, 2003, to September 30, 2023, and human studies. After 762 duplicates were eliminated, there remained 1,488 articles. Eleven final articles were deemed of the highest relevance to our topic by eliminating articles in animals, non-English language, reviews, meta-analysis, and off-topic. A potential risk in the third molar extraction was temporary loss of sensibility often caused by mild compression or irritation of the mandibular nerve. This typically resolves within weeks or months, but in severe cases, recovery might take longer. Permanent loss of sensation can occur, indicating significant nerve damage and lasting effects on touch, temperature, or pain perception.</p><p><strong>Conclusions: </strong>Various treatments exist for nerve damage, including low-level laser therapy, pain management medications, or physical therapy. While these therapies may improve neurosensory impairment, patients often report a decline in their quality of life.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"5415597"},"PeriodicalIF":1.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11405104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of External Precooling and Vibration Induced by BUZZY on Pain and Anxiety During Inferior Alveolar Nerve Block Injection in Children.","authors":"Reyhane Narimany, Reyhaneh Faghihian, Mehdi Jafarzadeh Samani","doi":"10.1155/2024/5515522","DOIUrl":"https://doi.org/10.1155/2024/5515522","url":null,"abstract":"<p><p><b>Purpose:</b> Children's fear of the injection of local anesthetic agents affects their cooperation in pediatric dentistry. Different techniques are available to decrease the injection pain, including the use of precooling agents or vibrators. The present study investigated the effectiveness of Buzzy (Buzzy MMJ Labs, Atlanta, GA, USA). This device transfers cold and external vibration to the injection site during the inferior alveolar nerve block (IANB) injection. <b>Materials and Methods:</b> The present self-control, randomized, and double-blind clinical trial evaluated 30 children aged 6-12, who had bilateral mandibular permanent or primary carious molar teeth. On one side, the BUZZY was applied before and during the IANB injection, and the other side was considered as control. On both sides, a topical anesthetic gel was applied before injection. The pain severity and children's anxiety were determined using Wong-Baker, face, leg, activity, cry, consolability (FLACC) scales, and the heart rate. <b>Results:</b> The mean age of the participants was 7.18 ± 1.5 years, with 12 girls and 18 boys. The Wong-Baker scale and FLACC scale did not show any statistically significant difference between BUZZY and control (<i>p</i> value = 0.9 and 0.15, respectively). In addition, BUZZY tool did not significantly decrease pain and anxiety during injection, assessed through the heart rate difference (<i>p</i>=0.38). <b>Conclusion:</b> Under the limitations of the present study, a combination of precooling and vibration using the BUZZY device did not decrease pain and anxiety in children during the IANB injection.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"5515522"},"PeriodicalIF":1.9,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11392579/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undiagnosed Celiac Disease and Periodontal Bone Loss: A Cross-Sectional Radiological Assessment from the HUNT Study.","authors":"Ida Haukåen Stødle, Odd Carsten Koldsland, Polina Lukina, Ina L Andersen, Patricia Mjønes, Elin Rønne, Hedda Høvik, Eivind Ness-Jensen, Anders Verket","doi":"10.1155/2024/1952244","DOIUrl":"https://doi.org/10.1155/2024/1952244","url":null,"abstract":"<p><strong>Objective: </strong>The objective was to assess radiographic periodontal bone loss in a population with previously undiagnosed celiac disease, and to compare it to a reference group without celiac disease.</p><p><strong>Background: </strong>Periodontitis and celiac disease are chronic inflammatory diseases with possible similar features related to immune reactions and microbial dysbiosis. The relationship between these two diseases is not clear.</p><p><strong>Methods: </strong>Clinical variables, blood samples, and answers to questionnaires were collected from participants in the fourth Trøndelag Health Study (HUNT4). Celiac disease was determined based on transglutaminase 2 (TG2), immunoglobulin A (IgA), and G (IgG) in serum samples. Seropositive individuals were invited to endoscopic examination and tissue sampling. Radiographically assessed bone loss caused by periodontitis in two different levels of severity was applied as outcome, that is, ≥15% and >33% of root length. Bone loss was determined in panoramic images in participants that had attended radiographic examination in the HUNT4 Oral Health Study or in the HUNT4 Coeliac Disease Study. The association between previously undiagnosed celiac disease and radiographic bone loss was estimated by adjusted Poisson regression models.</p><p><strong>Results: </strong>Radiographic assessment was completed in 485 individuals with celiac disease determined by positive serology and in 4,727 individuals with negative serology (without celiac disease). Compared to nonceliacs, seropositive participants were less likely to present with ≥15% radiographic bone loss (prevalence ratio (PR) 0.89 (95% CI 0.84-0.96). A similar association was also observed after histopathological confirmation of celiac disease (PR 0.89 (95% CI 0.82-0.98). No association between undiagnosed celiac disease and periodontal bone loss was observed when analyses were limited to individuals with severe bone loss (>33%).</p><p><strong>Conclusion: </strong>In this study of previously undiagnosed celiac disease and periodontal bone loss, newly diagnosed celiac disease was associated with less likelihood of presenting with ≥15% radiographic bone loss compared to a nonceliac reference group.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"1952244"},"PeriodicalIF":1.9,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11383648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Color Changes in Artificially Induced Incipient Caries after Photodynamic Therapy with Different Concentrations of Methylene Blue and Toluidine Blue and Irrigation with Water and Hypochlorite.","authors":"Sedighe Sadat Hashemikamangar, Mohammadreza Khadivi Moghadam, Mahtab Vahedi, Marzieh Rohaninasab, Nasim Chiniforush","doi":"10.1155/2024/6624453","DOIUrl":"10.1155/2024/6624453","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to assess the color changes in artificially induced incipient caries after photodynamic therapy (PDT) using different concentrations of methylene blue and toluidine blue, along with irrigation using water and hypochlorite.</p><p><strong>Materials and methods: </strong>Forty-two sound human premolar teeth were used to create two artificial incipient carious lesions. One lesion was placed on the buccal surface and the other on the lingual surface. The color of these artificial incipient carious surfaces was determined using the CIE <i>L</i>  ^<i>∗</i> <i>a</i>  ^<i>∗</i> <i>b</i>  ^<i>∗</i> color system. The teeth were then randomly assigned to 12 groups (<i>n</i> = 7) based on the PDT method. These methods included methylene blue with concentrations of 50, 100, and 150 <i>µ</i>g/mL, followed by water irrigation, methylene blue with concentrations of 50, 100, and 150 <i>µ</i>g/mL, followed by hypochlorite solution irrigation, toluidine blue with concentrations of 50, 100, and 150 <i>µ</i>g/mL, followed by water irrigation, and toluidine blue with concentrations of 50, 100, and 150 <i>µ</i>g/mL, followed by hypochlorite solution irrigation. The teeth underwent a colorimetry procedure again, and the resulting color changes were calculated. A three-way ANOVA was performed to analyze the effects of laser wavelength, concentration of the light-absorbing material, and irrigation solution on <i>ΔE</i>.</p><p><strong>Results: </strong>The results showed that the color changes caused by toluidine blue photosensitizer at a concentration of 100 <i>µ</i>g/mL, with both water and hypochlorite irrigation, were not noticeable to the naked eye (<i>ΔE</i>water = 3.04, <i>ΔE</i>hypochlorite = 2.00). However, in the other study groups, the color changes were perceptible (<i>ΔE</i> > 3.3). There were no significant differences in <i>ΔE</i> between different concentrations of methylene blue and toluidine blue when using either water or hypochlorite irrigation (<i>P</i>  > 0.05). A significant difference was observed between methylene blue and toluidine blue at a concentration of 100 <i>µ</i>g/mL with water irrigation (<i>P</i>=0.006). Additionally, a significant difference was found between methylene blue and toluidine blue at a concentration of 100 <i>µ</i>g/mL with hypochlorite irrigation (<i>P</i>=0.049). However, no significant differences were observed between methylene blue and toluidine blue at other concentrations with either water or hypochlorite irrigation (<i>P</i>  > 0.05).</p><p><strong>Conclusion: </strong>In conclusion, tooth color in teeth with incipient caries did not change significantly after PDT using toluidine blue (the photosensitizer) at a concentration of 100 <i>µ</i>g/mL with either water or 1% hypochlorite solution irrigation for 5 s.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"6624453"},"PeriodicalIF":1.9,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11379501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142153970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>In Vitro</i> Characterisation of 3D Printable Filaments Subjected to Edible Liquids: An Analysis of Fused Deposition Modelling for Intraoral Applicability.","authors":"Nafij Bin Jamayet, Aparna Barman, Farah Rashid, Sumaiya Zabin Eusufzai, Mutlu Özcan, James Dudley, Taseef Hasan Farook","doi":"10.1155/2024/2118412","DOIUrl":"https://doi.org/10.1155/2024/2118412","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the influence of edible liquids on the characteristic properties of 3D printable materials compared to conventionally used dental resin acrylic.</p><p><strong>Method: </strong>Dental polymethyl methacrylate (PMMA) specimens were fabricated from preformed molds while polylactic acid (PLA) and polyethylene terephthalate glycol (PETG) specimens were 3D printed using fused deposition modelling at 0.1 mm layer thickness. All specimen forms adhered to ISO 37:2017 and ISO 604:2002 specifications. Specimens underwent controlled immersion for 180 hr into different media (no immersion (control), oil, soda, milk, and caffeine). Changes in mass (g), plastic deformity (N/mm²), ultimate tensile stress (N), flexural deformity (N/mm²), and break force (N) were evaluated using analysis of variance.</p><p><strong>Results: </strong>There was an increase in mass for all specimens following immersion with significant interactions between immersion media and the materials. The materials exhibited significant differences in plastic deformity (<i>F</i> (df) = 156.632(2), <i>P</i>  < 0.001), ultimate tensile stress (<i>F</i> (df) = 109.521(2), <i>P</i>  < 0.001), and break force (<i>F</i> (df) = 319.785 (2), <i>P</i>  < 0.001) with no significant interactions with immersion media (<i>P</i> > 0.05) on both accounts. Materials showed no significant differences in flexural deformity (<i>F</i> (df) = 2.693(2), <i>P</i> = 0.074) but with significant interactions (<i>F</i> (df) = 4.984(8), <i>P</i>  < 0.001) between acrylic and immersion media.</p><p><strong>Conclusion: </strong>Commercially available 3D printable PLA and PETG filaments printed at 0.1 mm thickness possess approximately half the mechanical resilience as dental PMMA with comparable flexural deformity after exposure to edible liquids.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"2118412"},"PeriodicalIF":1.9,"publicationDate":"2024-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11479776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142464554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Mechanical and Biological Properties of Zinc Phosphate Dental Cement with Akermanite and Hardystonite Nanoparticles: A Synthesis and Characterization Study.","authors":"Hossein Eslami, Mojtaba Ansari, Reihaneh Khademi, Hadi Zare-Zardini","doi":"10.1155/2024/4916315","DOIUrl":"10.1155/2024/4916315","url":null,"abstract":"<p><p>This study investigates the potential of incorporating akermanite and hardystonite nanoparticles (NPs) into commercially available zinc phosphate cement. Akermanite and hardystonite NPs were synthesized through a mechanical route and characterized using X-ray diffraction (XRD), fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM). The NPs were then added to the cement at a concentration of 5 wt%, and the physical and biological properties of the resulting composite were evaluated. The results showed that the incorporation of NPs led to a significant reduction in porosity (from 12.4% to 5.6%) and a notable improvement in compressive strength (from 90 to 120 MPa) compared to the control group. MTT assay revealed that the cement containing NPs exhibited no significant toxicity and even promoted cell growth and proliferation. Specifically, cell viability increased by 15%, and cell proliferation rate increased by 20% compared to the control group. These findings suggest that the designed cement has suitable mechanical and biological properties, making it a promising material for dental and orthopedic applications.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"4916315"},"PeriodicalIF":1.9,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11377109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142142336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Palatal Thickness for the Placement of MARPE Device among a Cohort of Iraqi-Kurdish Population: A Retrospective CBCT Study.","authors":"Fedil Andraws Yalda, Omar Fawzi Chawshli, Shaho Ziyad Al-Talabani, Sarkawt Hamad Ali, Omed Ikram Shihab","doi":"10.1155/2024/6741187","DOIUrl":"10.1155/2024/6741187","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate and compare palatal thickness in adults for the placement of mini-implants for miniscrew-assisted rapid palatal expansion (MARPE) appliances using cone-beam computed tomography (CBCT) in a sample of Iraqi-Kurdish people.</p><p><strong>Materials and methods: </strong>CBCT scans from 68 Kurdish patients, aged between 18 and 30 years, were assessed retrospectively. Of these, 37 were males and 31 were females. The measurements were performed at 3 mm from the mid-palatal suture. T-zone was selected for the anterior points, at the level of the palatal cusps of 2nd premolars, and the posterior point at the level of mesio-palatal cusps of 1st molars bilaterally. Palatal thickness of males and females bilaterally, as well as anterior and posterior areas, were measured and compared. An independent <i>t</i>-test was applied for comparison for normally distributed data, and the Mann-Whitney test was utilized for nonnormally distributed data. Additionally, Bonferroni correction was implemented for <i>p</i>-value adjustment.</p><p><strong>Results: </strong>The mean palatal thickness at the anterior area was 6.06 mm for males, 6.17 mm for females on the right side, 5.94 mm for males, and 5.99 mm for females on the left side. The mean palatal thickness at the posterior area was almost the same for both genders (4.40 mm for males and 4.44 mm for females) on the right side, 4.35 mm for males, and 4.54 mm for females on the left side. Statistically, no significant difference was recorded between males and females, as well as right and left sides in both anterior and posterior regions; however, a very highly statistically significant difference (<i>p</i>  < 0.001) was recorded when comparing total thickness, including both hard and soft tissue, between anterior and posterior regions.</p><p><strong>Conclusions: </strong>CBCT proves a highly effective modality in assessing palatal thickness and suggesting ideal locations for orthodontic mini-screw placement. Our examination of palatal thickness in a sample of Iraqi-Kurdish individuals revealed no statistical difference between genders or sides, but significant variations were noted between anterior and posterior thicknesses. Comprehensive clinical and pre-expansion CBCT evaluations are crucial for precisely determining the optimal placement of MARPE devices in each patient, ensuring successful outcomes.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2024 ","pages":"6741187"},"PeriodicalIF":1.9,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11374425/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}