International Journal of Dentistry最新文献

{"title":"Assessing the Color and Surface Characteristics of Additively Fabricated Denture Base Resins Containing Nanoparticles.","authors":"Shaimaa M Fouda, Mohammed M Gad, Mai Salah El-Din, Soban Q Khan, Ahmed Othman, Constantin von See","doi":"10.1155/ijod/5177847","DOIUrl":"https://doi.org/10.1155/ijod/5177847","url":null,"abstract":"<p><p><b>Objective:</b> To investigate and compare the impact of different nanoparticles (NPs) on the color stability and surface properties of additively fabricated (AF) denture base resins after thermal cycling. <b>Materials and Methods:</b> Two hundred specimens (<i>n</i> = 10) were AF from NextDent and ASIGA denture base resins. Specimens were divided into four groups according to the added NP's type and concentration: nanodiamond (ND; 0.25% and 0.5%), silicon dioxide NPs (NS; 0.25% and 0.5%), and a control group of pure resin of each material. The color change (∆<i>E</i> _Lab), surface roughness, and hardness were tested after thermal cycling (5000 cycles). Data were analyzed using ANOVA and post hoc Tukey's tests (<i>α</i> = 0.05). <b>Results:</b> The ∆<i>E</i> _Lab was affected by the NP type and material type, while the NPs concentration showed no effect. ND showed higher ∆<i>E</i> _Lab with NextDent in all groups (<i>p</i>  < 0.05) in comparison to NS. Color change of ASIGA with ND and NS was higher than that of NextDent, ∆<i>E</i> _Lab values of all tested groups were below 3.7 NBS. For NextDent, 0.5% NS showed significantly the highest hardness values (25.9 ± 4.6 VHN) followed by 0.5% ND (18.7 ± 2.4 VHN). For hardness, NextDent 0.5% NS showed significant increase when compared with ASIGA (<i>p</i>  < 0.001). For roughness, NextDent 0.5% NS showed significantly less Ra than other groups. In term of materials comparison per NP type, significant differences in Ra between ASIGA and NextDent was detected. <b>Conclusions:</b> The effect of NP on the tested properties is concentration dependent and material dependent therefore, NP type, NP concentrations, and material type selection should be considered for AF nanocomposite denture base fabrication.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"5177847"},"PeriodicalIF":2.2,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Stress Distribution in 5-Unit Fixed Partial Dentures With a Pier Abutment and Rigid and Nonrigid Connectors With Two Different Occlusal Schemes: A Three-Dimensional Finite Element Analysis\".","authors":"","doi":"10.1155/ijod/9767959","DOIUrl":"https://doi.org/10.1155/ijod/9767959","url":null,"abstract":"<p><p>[This corrects the article DOI: 10.1155/2023/3347197.].</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"9767959"},"PeriodicalIF":2.2,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12316494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144775338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inhibition of Bone Resorption and Anti-Inflammatory Effect of 7-Hydroxycoumarin in an Animal Model of Lipopolysaccharide-Induced Periodontal Disease.","authors":"Luiza Teles Barbalho Ferreira, Renan Fernandes do Espírito-Santo, Milena Botelho Pereira Soares, José Maria Barbosa-Filho, Cristiane Flora Villarreal, Paulo José Lima Juiz","doi":"10.1155/ijod/9971146","DOIUrl":"10.1155/ijod/9971146","url":null,"abstract":"<p><p><b>Introduction:</b> Periodontal disease (PD) has a multifaceted etiology. The immune response to microbial invasion triggers osteoclast activation, leading to the resorption of alveolar bone and ultimately resulting in tooth loss. <b>Objective:</b> This study aims to investigate the anti-inflammatory properties of the bioactive compound 7-hydroxycoumarin (7HC) at concentrations of 50 and 100 mg/kg. We seek to evaluate its effectiveness in controlling alveolar bone resorption in treating PD induced by lipopolysaccharide (LPS) in an animal model. <b>Methodology:</b> PD was induced in C57 Bl/6 mice using a LPS injection protocol. The mice were randomly assigned to different treatment groups, receiving 7HC at 50 and 100 mg/kg, nimesulide at 25 mg/kg, and a control group that received the vehicle. Treatments were administered once daily from the 14th to the 28th day of the study. Following this treatment period, the animals were euthanized, and gingival tissue samples were collected to assess cytokine production (interleukin-1β [IL-1β] and interleukin-6 [IL-6]) using enzyme-linked immunosorbent assay (ELISA). Additionally, mRNA expression levels of matrix metalloproteinase-9 (MMP-9), TIMP-1, IL-10, and TGF-β were analyzed through qRT-PCR. The maxillae were extracted for the quantification of alveolar bone resorption by measuring the most significant distance between the cementoenamel junction and the alveolar bone crest (ABC) utilizing ImageJ software. <b>Results:</b> The bioactive 7HC effectively inhibited the expression of IL-1β, IL-6, and MMP-9, while simultaneously increasing the mRNA expression of IL-10 and TGF-β, cytokines recognized for their anti-inflammatory properties. Histometric analysis of the alveolar bone indicated that 7HC protects alveolar bone resorption in an animal model of PD induced by LPS injection. <b>Conclusion:</b> The bioactive 7HC not only inhibited proinflammatory cytokines but also stimulated the expression of the anti-inflammatory cytokine, thereby preventing bone resorption. This positions 7HC as a promising candidate for periodontal therapy.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"9971146"},"PeriodicalIF":2.2,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Effect of Escitalopram on Alveolar Bone Levels and Periodontal Parameters: A Case-Control Study.","authors":"Ayman Ahmed, Ehab Azab","doi":"10.1155/ijod/8637908","DOIUrl":"10.1155/ijod/8637908","url":null,"abstract":"<p><p><b>Objectives:</b> The purpose of the present study was to analyze the effect of escitalopram, a selective serotonin reuptake inhibitor, clinically and radiographically on bone levels and periodontal parameters. <b>Materials and methods:</b> A sample of 100 patients with clinical depression was assessed for clinical periodontal parameters including plaque index (PI), gingival index (GI), probing depth (PD), and clinical attachment loss (CAL) and radiographic marginal bone loss. A total of 50 patients were administered 10 mg escitalopram daily for 3-6 months, while the other 50 patients did not receive it. <i>p</i>-Values < 0.05 with a 95% confidence interval were considered statistically significant. <b>Results:</b> No statistically significant difference in the PI was found among the study groups (<i>p</i> > 0.05). Conversely, a significantly lower GI, PD, and CAL were found in the escitalopram users group (<i>p</i> < 0.001). Moreover, mesial and distal radiographic marginal bone loss were significantly lower in the escitalopram users group than in the nonescitalopram users group (control) (<i>p</i> < 0.001). <b>Conclusion:</b> The present study indicates that escitalopram intake in patients with clinical depression is associated with lower periodontal parameter scores and decreased marginal bone loss.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"8637908"},"PeriodicalIF":2.2,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New Classification of Autologous Tooth-Derived Grafting Materials: Fundamental Concepts.","authors":"Elio Minetti, Silvio Taschieri, Marco Berardini, Stefano Corbella","doi":"10.1155/ijod/6646405","DOIUrl":"10.1155/ijod/6646405","url":null,"abstract":"<p><p>The use of dentin grafts is relatively recent, and their efficacy remains a topic of debate. Various techniques and devices are available for dentin grafting; however, their application has been inconsistent, as each method yields a distinct product with unique biological properties and potential uses. One of the challenges that arises with the introduction of a new biomaterial is the potential confusion between different preparations. Specifically, generalization may significantly impact the understanding of unique qualities and/or potential limitations. The various materials that make up the family of tooth-derived graft materials share only one common starting point: the patient's extracted tooth. Beyond that, the processes of grinding, demineralization, and detoxification differ significantly, resulting in final materials with completely different percentages of minerals, bone morphogenetic proteins (BMPs), collagenic and noncollagenic proteins, and residual bacterial load. These differences influence the regenerative potential of one material compared to another, as well as the resorption rate. For instance, incomplete sterilization of the material can accelerate the resorption process, leading to insufficient regeneration. Here, we propose a classification of dentin grafts into four categories based on their processing methods. This classification aims to clarify the successes and challenges encountered to date, offering an objective framework to guide the ongoing development of these techniques. The aim of this study is to establish the first classification system of autogenous partial demineralized tooth-derived grafting biomaterials.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"6646405"},"PeriodicalIF":2.2,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12310315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Diagnostic Reliability of CBCT for Vertical Root Fractures: A Systematic Review and Meta-Analytical Approach.","authors":"Luiz Carlos de Lima Dias-Junior, Diego Leonardo de Souza, Adriana Pinto Bezerra, Marcio Correa, Cleonice da Silveira Teixeira, Eduardo Antunes Bortoluzzi, Lucas da Fonseca Roberti Garcia","doi":"10.1155/ijod/8824867","DOIUrl":"10.1155/ijod/8824867","url":null,"abstract":"<p><p>This systematic review investigated the different factors associated with the diagnostic accuracy of vertical root fractures (VRFs) with cone-beam computed tomography (CBCT) scans, assessed by in vitro studies. Studies were screened from PubMed, Embase, Scopus, Web of Science, and Lilacs, up to May 2025. The included studies assessed the diagnostic accuracy of CBCT scans for laboratory-induced VRFs. The quality assessment of the included studies was performed using the QUADAS-2 tool. Meta-analyses were performed using the bivariate model with random effects to produce summary sensitivity (SSe) and specificity (SSp) with a 95% confidence interval (CI). The influence of confounding factors on the accuracy of CBCT images was investigated by meta-regression models. Covariates were added to the bivariate model to assess the impact on sensitivity, specificity, or both. The quality of evidence of each meta-analysis was assessed using the GRADE approach. One hundred studies were included. Twenty-four studies presented a low risk of bias, 22 moderate risk, and 54 high risk. CBCT scans presented a higher sensitivity for the diagnosis of complete VRFs compared to incomplete fractures. The presence of metal posts impaired both sensitivity and specificity. Smaller voxel sizes favored the detection of VRFs in teeth with metal posts. In laboratory settings, the diagnosis of VRFs by CBCT images is mainly affected by the fracture pattern, presence of intracanal materials, and voxel size.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"8824867"},"PeriodicalIF":2.2,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303641/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Periodontal Health and Total Antioxidant Capacity for Jordanian Smokers at Dental Teaching Clinic.","authors":"Noor Al Mortadi, Khaled Al Qudah, Sabha Alshatrat, Karem H Alzoubi, Rania Mahafdeh","doi":"10.1155/ijod/3075190","DOIUrl":"10.1155/ijod/3075190","url":null,"abstract":"<p><p><b>Background:</b> Smoking exacerbates oxidative stress and inflammation, both of which contribute to periodontitis. However, few studies have simultaneously assessed/systemic antioxidant capacity, organ function, and hematological indices in smokers with periodontitis. This study aimed to examine antioxidant enzymes, hepatic and renal function, and hematological profiles, offering a comprehensive perspective on smoking-related periodontal damage. <b>Methods:</b> A total of 47 participants were divided into three groups: smokers with periodontitis (<i>n</i> = 18), nonsmokers with periodontitis (<i>n</i> = 17), and healthy nonsmoking controls without periodontitis (<i>n</i> = 12). Salivary and blood samples were collected, and oxidative stress biomarkers, including thiobarbituric acid reactive substances (TBARS) and antioxidant enzymes, such as glutathione (GSH), GSH peroxidase (GPX), superoxide dismutase (SOD), and total antioxidant activity (TAOA), were measured. Additionally, liver function (ALT, AST, GGT, Total bilirubin), kidney function (BUN, creatinine), and hematological parameters were assessed and compared among the three groups. <b>Results:</b> Smokers with periodontitis illustrate significant elevation in TBARS levels in both serum and saliva (<i>p</i>  < 0.05), indicating increased oxidative stress compared to nonsmokers and controls. Serum antioxidant enzyme levels (GSH, GPX, SOD, and TAOA) were significantly decreased in the smokers with periodontitis groups (<i>p</i>  < 0.05). ALT and AST levels were significantly elevated in the smoking and periodontitis group (44.45 ± 19.64 and 28.27 ± 7.77 U/L), respectively, suggesting significant liver impairment among smokers (<i>p</i>  < 0.05). Kidney function was also affected; the BUN and creatinine levels were noticeably higher in smokers compared to the healthy controls and nonsmokers (<i>p</i>  < 0.05). Hematological findings exhibit a significant increase in WBCs among smokers-periodontitis patients, indicating an increase in systemic inflammation. <b>Conclusion:</b> The imbalance between oxidative stress and antioxidant capacity may play a role in the pathogenesis of periodontal disease. Smoking is highly linked to oxidative stress-antioxidant (redox) imbalance, which exacerbates the impact of periodontitis. This leads to significant oxidative damage, noticeable liver and kidney dysfunction, and elevated systemic inflammation.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"3075190"},"PeriodicalIF":2.2,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effectiveness of Single-Visit and Multi-Visit Root Canal Treatment on Healing Intraoral Sinus Tract.","authors":"Fatma Begüm Peker, Mehmet Burak Güneşer","doi":"10.1155/ijod/4200682","DOIUrl":"10.1155/ijod/4200682","url":null,"abstract":"<p><p><b>Objective:</b> This research sought to investigate and compare the levels of postoperative discomfort and the rate of intraoral sinus tract healing in teeth affected by chronic apical periodontitis, treated either through single-visit (SV) root canal therapy (RCT) or multi-visit (MV) therapy employing calcium hydroxide as an intracanal medicament. <b>Materials and Methods:</b> A total of 60 participants, aged between 18 and 65 years, with single-rooted teeth exhibiting single canals, radiographic evidence of apical periodontitis, and associated intraoral sinus tracts, were included in the study. The participants were randomly divided into two treatment groups: Group 1 underwent SV therapy, while Group 2 received MV therapy. In the MV group, calcium hydroxide was introduced as an intracanal dressing following the preparation phase, and the root canal obturation was performed in a subsequent session after 1 week. In the SV group, obturation was completed in the same session. For the MV group, calcium hydroxide was removed during the second visit, the irrigation procedure was repeated, and obturation was finalized. Pain levels were measured postoperatively using a visual analog scale (VAS). Participants documented their pain at 6 and 12 h following treatment, as well as daily for the next 2 days. In the MV group, pain was additionally evaluated at the beginning of the second session, and patients were asked to report any pain experienced during the interval between visits. Follow-up appointments were conducted to assess the progress of sinus tract healing, which was defined as the complete closure or resolution of the tract over a 14-day period. Data were analyzed using the two-sample proportion test and Pearson's chi-square test, with statistical significance set at <i>α</i> = 0.05. <b>Results:</b> The findings indicated no statistically significant differences between the two groups regarding the frequency of postoperative pain (<i>p</i> > 0.05). Median scores showed that VAS scores were highest after 6 h (Mdn = 3, IQR = 5.25), followed by 12 h (Mdn = 3, IQR = 6), after 24 h (Mdn = 0, IQR = 3.25), and after 48 h (Mdn = 0, IQR = 3). In both groups, pain levels at the 6^th h were found to be higher than at the 48^th h (<i>p</i> < 0.05). Mean recovery time was 6.8 days for the SV group and 6.56 days for the MV group. The duration required for sinus tract healing showed no significant variation between the SV and MV treatment modalities (<i>p</i> > 0.05). <b>Conclusion:</b> Both SV and MV root canal treatments (RCTs) yielded comparable outcomes in terms of postoperative pain levels and the time necessary for sinus tract resolution, with no statistically significant differences observed between the two approaches. The observed similarity in healing parameters and pain levels suggests that both treatment methods demonstrate comparable clinical effectiveness.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"4200682"},"PeriodicalIF":2.2,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12289366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunohistochemical Analysis to Evaluate the Efficacy of Tetracycline-Loaded Nano-Chitosan in Treating Periodontitis Induced by <i>Porphyromonas gingivalis</i> in Albino Rats.","authors":"Mashael Saeed Alqahtani, Rania Hanafi Mahmoud Said","doi":"10.1155/ijod/1959086","DOIUrl":"10.1155/ijod/1959086","url":null,"abstract":"&lt;p&gt;&lt;p&gt;&lt;b&gt;Aim:&lt;/b&gt; In this study, we examined the efficacy of tetracycline (TC) loaded on nano-chitosan in alleviating &lt;i&gt;Porphyromonas gingivalis&lt;/i&gt;-induced periodontitis in albino rats. The location of the proinflammatory cytokine interleukin-1beta (IL-1β) was examined via immunohistochemistry. &lt;b&gt;Methods:&lt;/b&gt; Mature Wistar albino rats (&lt;i&gt;n&lt;/i&gt; = 30; 150-180 g) were used in this study. The samples were split into five equal groups at random. The rats in all groups were subjected to antibiotics (for 3 days) in drinking water 1 week before the experiment started. Group I, which served as a control group, consisted of six albino rats. All groups except the control group were subjected to &lt;i&gt;P. gingivalis&lt;/i&gt; injection by micro-pipetting 3 days weekly after ligation of the upper first molar (M1) for 4 weeks. Group II consisted of six rats that were injected with &lt;i&gt;P. gingivalis&lt;/i&gt; twice weekly for 30 days. Six rats were assigned to Group III and subjected to the same treatments as those in Group II. However, in Group III, the infected regions were also injected with diluted TC powder daily for 2 weeks. Group IV was subjected to the same procedure as Group II before daily injections of nano-chitosan at the injection sites for 2 weeks. Group V consisted of six rats; once daily, they were administered localized injections of TC loaded on nano-chitosan for 2 weeks after the same procedure as Group II. After the rats were anesthetized, the maxilla, including the teeth and surrounding alveolar bone, was dissected. Light microscopy was performed for histological and immunohistochemical examinations of the biopsies. To check the normal distribution of samples Shapiro-Wilk test was performed, to determine the differences between the groups one-way analysis of variance (ANOVA) test was used, and to compare the groups pairwise, a Bonferroni post hoc correction was carried out. The results were statistically significant when &lt;i&gt;p&lt;/i&gt; ≤ 0.05. &lt;b&gt;Results:&lt;/b&gt; Histological examination revealed that the periodontal tissues in Group I were normal. An increase in inflammatory cells (plasma cells, lymphocytes, and macrophages) was found in Group II, with alveolar bone resorption. A decrease in the number of dilated blood vessels and resorption areas was found in Group III. Inflammation and resorption in alveolar bone persisted in Group IV. In Group V, few dilated blood vessels were observed, with a decrease in inflammatory cells and alveolar bone deposition. Immunohistochemical examination revealed a significant difference in the level of IL-1β in the periodontal ligaments and alveolar bone between the negative control group and all other groups; however, the level of IL-1β in the alveolar bone was not significantly different between Groups II, III, and IV, whereas a significant difference in the level of IL-1β was detected between the different groups of periodontal ligaments. &lt;b&gt;Conclusion:&lt;/b&gt; Nano-chitosan may combat increasing TC resistance, with a noticeable","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"1959086"},"PeriodicalIF":1.9,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12279421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144682605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visit Characteristics Associated With Pediatric Dental Appointment No-Shows in an Academic Dental Setting.","authors":"Rubelisa C G de Oliveira, Hassan Khalid, Zhaoqi Zhang, Saptarshi Chakraborty, Daniela Benzano, Jessica S Kruger, Susan C McKernan","doi":"10.1155/ijod/2114933","DOIUrl":"10.1155/ijod/2114933","url":null,"abstract":"<p><p><b>Objectives:</b> Dental no-show rates negatively impact oral health outcomes, especially among adolescents. While many factors can be associated with no-show in dental appointments, adolescents' no-show rates are influenced by parents' or caregivers' experiences and decisions. This study aims to investigate patient visit-related characteristics that are associated with failure to attend scheduled dental appointments in an academic institution located in Buffalo, New York (NY), a region impacted by health disparities. <b>Methods:</b> A secondary analysis was performed with multivariables extracted from the electronic health records of individuals aged 0-19 years from 2018 to 2023. Bivariate and multivariate analyses at the visit level were performed to compare show/no-show groups concerning demographics, payor at the time of dental appointment, distance from home to dental facility, and Social Deprivation Index (SDI) scores related to their ZIP codes. <b>Results:</b> A total of 7379 visits were included in the analysis. 14.3% were no-shows. Adolescents aged 12-17 years accounted for the greatest no-show rate (24%) when compared with younger children. Age had an increased likelihood of no-show (OR = 1.13, CI = 1.11-1.15), and social deprivation had a slight protective effect in no-show at dental appointments in this academic institution (OR = 0.98, CI = 0.98-0.99). The great majority of pediatric patients come from socioeconomically deprived areas and live further away from the school. <b>Conclusions:</b> Adolescents are the group at most risk of no-show. Future studies should explore strategies to better understand the barriers related to this lifespan as well as implement interventions that facilitate scheduling as well as prevent no-shows.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2025 ","pages":"2114933"},"PeriodicalIF":1.9,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12274092/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}