International Journal of Dentistry最新文献

{"title":"Comparative Evaluation of Buccal Cortical Bone Thickness in the Posterior Mandible Across Skeletal Patterns: A CBCT Study in a Sample of Iranians.","authors":"Paniz Ranji, Kazem Dalaei, Melika Mansouri, Yaser Safi, Maede Jafarian Amiri, Mehdi Hosseinzadeh","doi":"10.1155/ijod/1205123","DOIUrl":"https://doi.org/10.1155/ijod/1205123","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate buccal cortical bone thickness in the posterior mandible across different sagittal and vertical skeletal patterns using cone-beam computed tomography (CBCT).</p><p><strong>Materials and methods: </strong>In this retrospective observational study, cortical buccal bone thickness between posterior teeth was assessed at 4 and 7 mm distances from the alveolar crest using CBCT images of 112 Iranian participants aged 18-60 years. Participants were classified into six groups: Class I normal angle, Class I low angle, Class I high angle, Class II normal angle, Class II low angle, and Class II high angle. Statistical analyses included the Shapiro-Wilk test, Levene's test, multivariate analysis of variance (MANOVA), paired-sample <i>t</i>-test, and intraclass correlation coefficient (ICC), with a significance level set at <i>α</i> = 0.05.</p><p><strong>Results: </strong>Cortical bone thickness generally increased from anterior to posterior regions and from the alveolar crest toward the basal jaw in Class II and both high- and low-angle groups, with exceptions observed in Class I and normal-angle individuals. Statistically significant differences in cortical bone thickness were observed between Class I and Class II skeletal patterns at specific posterior sites, with Class I individuals consistently exhibiting greater thickness. Differences related to vertical skeletal pattern were limited, observed only at the distal canine (4-mm level). Sex, age, and side-to-side differences influenced cortical thickness in certain regions, with slightly greater thickness on the left side at some measurement sites.</p><p><strong>Conclusions: </strong>Buccal cortical bone thickness in the posterior mandible varies significantly with the sagittal skeletal pattern, whereas the vertical skeletal pattern has minimal influence.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"1205123"},"PeriodicalIF":2.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13131059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical Variations in Permanent Mandibular Molars in the Sharjah Population: A Cohort Study Using Cone-Beam Computed Tomography.","authors":"Shaima Dheyab, Entisar AlRasasi, Ahmed M Aziz, Saad Albayatti, Mehmet Omer Gorduysus","doi":"10.1155/ijod/5613749","DOIUrl":"https://doi.org/10.1155/ijod/5613749","url":null,"abstract":"<p><strong>Objective: </strong>This cohort study aimed to assess the prevalence of anatomical variations, including radix entomolaris (RE), radix paramolaris (RP), middle mesial canal (MMC), and C-shaped canal, in the permanent mandibular first and second molars across different nationalities and genders.</p><p><strong>Materials and methods: </strong>A total of 777 cone-beam computed tomography scans were retrospectively evaluated from patients receiving routine dental treatment at the University Dental Hospital, Sharjah, United Arab Emirates (UAE), of which 165 met the inclusion criteria. Descriptive statistics were presented as the overall number of canals and the prevalence and distribution of RE, RP, MMC, and C-shaped canals in the permanent mandibular first and second molars. Chi-square tests were performed for comparative analyses.</p><p><strong>Results: </strong>None of the mandibular first molars included had RE, RP, or MMC. No gender differences were detected. One participant (0.30%) had a C-shaped canal configuration. In mandibular second molars, the overall prevalence of C-shaped canal anatomy was 4.54%, and 0.30% for RE. A case of RE was exclusively observed in one first molar, with no instances of RP or MMC identified in our study population.</p><p><strong>Conclusion: </strong>In this study, the majority of permanent first molars exhibited two roots and four canals, while permanent second molars most frequently had two roots and three canals, with greater variations revealed in second molars and most frequently observed in Pakistani patients. A C-shaped canal configuration was more common in the second molars than in the first ones. Overall, Asian and African ethnicities tended to have significantly more canal variations than Western populations.</p><p><strong>Clinical significance: </strong>The clinical relevance of this study lies in its potential to enhance diagnostic accuracy, treatment planning, and patient outcomes by understanding common variations and their prevalence across various ethnic groups. Therefore, clinicians can better anticipate the challenges and implications of treatment.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"5613749"},"PeriodicalIF":2.2,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13130136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Digital Restorative Dentistry: Evaluation of Clinical Outcome Parameters of CAD/CAM and 3D-Printed Inlays, Onlays, and Veneers-Scoping Review.","authors":"Syed Nahid Basheer, Syed Wali Peeran","doi":"10.1155/ijod/7117281","DOIUrl":"https://doi.org/10.1155/ijod/7117281","url":null,"abstract":"<p><strong>Background: </strong>Digital workflows have revolutionized restorative dentistry, computer-aided design and computer-aided manufacturing (CAD/CAM) milling, and three-dimensional (3D) printing provide alternatives to conventional methods of fabrication of inlays, onlays, and veneers. However, comparative evidence of their clinical performance remains scattered.</p><p><strong>Aim: </strong>This scoping review aimed to map and synthesize current evidence on the clinical outcomes of CAD/CAM- and 3D-printed inlays, onlays, and veneers, focusing on adaptation, strength, esthetics, and workflow efficiency.</p><p><strong>Methodology: </strong>This scoping review followed the methodological framework proposed by Arksey and O'Malley, with refinements suggested by Levac et al., and was reported in accordance with the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews). A comprehensive search was performed in PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar for studies published from January 2000 to June 2025. Eligible studies included in vitro, clinical, and case-based reports that evaluated CAD/CAM or 3D-printed inlays, onlays, or veneers. Data were charted and analyzed thematically according to restoration type, fabrication method, material, and reported outcomes.</p><p><strong>Result: </strong>Thirty studies were included, mainly in vitro. Inlays showed clinically acceptable adaptation, with 3D printing achieving accuracy comparable to milling, while ceramics offered superior hardness. Onlays yielded mixed outcomes: pressable ceramics had higher strength, but 3D-printed onlays often showed better adaptation. Veneers demonstrated the greatest potential for 3D printing, with printed zirconia and lithium disilicate performing well. CAD/CAM was faster and well established, whereas 3D printing provided greater customization but longer fabrication times.</p><p><strong>Conclusion: </strong>In conclusion, both CAD/CAM and 3D printing are capable of producing inlays, onlays, and veneers with clinically acceptable accuracy and strength. CAD/CAM remains the most established and reliable technique, particularly for ceramics, whereas 3D printing shows potential to enhance adaptation and customizability, especially for veneers. Further clinical trials are essential to validate long-term outcomes.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"7117281"},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13127349/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Roles of Fimbriae and Gingipain Genotypes in <i>Porphyromonas gingivalis</i> and Their Association With Periodontitis Severity.","authors":"Manohar Kugaji, Kishore Bhat, Uday Muddapur, Ram Surath Kumar, Suman Kumar Ray, Eswar Kandaswamy, Vinayak Joshi","doi":"10.1155/ijod/6236248","DOIUrl":"https://doi.org/10.1155/ijod/6236248","url":null,"abstract":"<p><strong>Objective: </strong><i>Porphyromonas gingivalis</i> is a major periodontal pathogen periodontitis, with virulence mediated by fimbriae and gingipains. Differences in virulence may influence disease severity. This study aimed to assess the association and co-occurrence of fimbriae and gingipain genotypes and their relationship with clinical severity in periodontitis.</p><p><strong>Materials and methods: </strong>This secondary analysis included 120 subgingival plaque samples from patients with periodontitis. Fimbriae (<i>fimA</i> types I-V) and gingipain (<i>kgp</i>, <i>rgpA</i>) genotypes were identified using PCR and restriction enzyme digestion, and <i>P. gingivalis</i> load was quantified by real-time PCR. Associations between genotypes and clinical parameters (probing depth and clinical attachment loss) were evaluated using Spearman's correlation and chi-square tests. Binary logistic regression assessed the association between periodontal disease severity and the presence of a combined virulence genotype, reported as odds ratios (ORs).</p><p><strong>Results: </strong>The <i>fimA</i> types II and III and gingipain genotypes <i>kgp-I</i> and <i>kgp-II</i> were significantly associated with deeper PD and greater CAL (<i>p</i>  < 0.05). <i>fimA</i> type II was the most prevalent across all bacterial load percentiles, followed by type IV. <i>kgp-I</i> and <i>rgpA</i> type A were correlated with higher <i>P. gingivalis</i> counts. Significant positive correlations were observed between fimbriae and gingipain genotypes (<i>p</i>  < 0.05). Patients with CAL ≥5 mm had significantly higher odds of harboring the combined virulence genotype than those with CAL <5 mm (OR = 3.56; 95% CI: 1.43-8.47; <i>p</i> = 0.011).</p><p><strong>Conclusion: </strong>Specific fimbriae and gingipain genotypes co-occur and are linked to increased bacterial load suggesting synergistic roles in the pathogenicity of <i>P. gingivalis</i>. The findings support the hypothesis that these virulence factors act synergistically to influence disease severity.</p><p><strong>Clinical relevance: </strong>The integration of microbial virulence profiling with host immune response characterization may improve risk stratification and enable the development of personalized periodontal care strategies. Furthermore, microbial genotypic profiling may support the identification of disease-specific targets, thereby facilitating the implementation of tailored therapeutic interventions for effective periodontitis management.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"6236248"},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13125940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Influence of Access Cavity Design to Detect Additional Canals of Mandibular Premolars: An In Vitro Study.","authors":"Maryam Javidi, Ali Kazemian, Mina Zarei, Hasti Erfanian Taghvaei, Melika Mohammadi","doi":"10.1155/ijod/5575879","DOIUrl":"https://doi.org/10.1155/ijod/5575879","url":null,"abstract":"<p><strong>Objective: </strong>The present in vitro study aimed to investigate the impact of three different access cavity types on the identification of the additional canals in mandibular premolars.</p><p><strong>Methods and materials: </strong>A total of 67 mandibular premolars were obtained, and periapical radiographs and CBCT scans were taken. Then, the access cavities were created in three stages: ultraconservative access cavity (UltraAC), conservative access cavity (CAC), and traditional access cavity (TAC). After completing each stage, the search for the second and third canals was conducted under a surgical microscope, using ultrasonic troughing. The differences between the three access cavity designs in identifying the second and third canals were compared using the chi-squared test. Additionally, the agreement between periapical radiographs, CBCT, and the operator in finding the canals was determined by measuring the kappa coefficient (<i>p</i>.value = 0.05).</p><p><strong>Results: </strong>62.68%, 34.32%, and 2.98% of the samples had one, two, and three root canals, respectively. The agreement between PA radiographs and CBCT images in identifying the number of canals was almost perfect (kappa: 0.968; <i>p</i>  < 0.001). Additionally, the agreement between the operator and initial PA radiographs and between the operator and CBCT in detecting the number of canals was substantial (kappa: 0.735 and 0.794, respectively; <i>p</i>  < 0.001). No difference was observed between the access cavity types in identifying the second and third canals. Of the two three-canal teeth, one was found in the TAC stage and the other in the CAC stage.</p><p><strong>Conclusion: </strong>When the access cavity of mandibular premolars is prepared using magnification with a microscope and ultrasonic troughing, the design of the access cavity has no effect on identifying the additional canals in these teeth.</p><p><strong>Clinical relevance: </strong>Mandibular premolars are reported to have more than one canal, and the effect of different access cavities has not been evaluated in canal detection of these teeth.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"5575879"},"PeriodicalIF":2.2,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13126083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Swallowing and Tongue Strength Index in Patients With Temporomandibular Dysfunction: A Cross-Sectional Study.","authors":"Julia da Silva Germiniani, Milena Sampaio Kuczera, Aline Xavier Ferraz, Rosane Sampaio Santos, Bianca Simone Zeigelboim, Cristiano Miranda de Araujo, Glória Maria Nogueira Cortz Ravazzi, Flavio Magno Gonçalves, José Stechman-Neto","doi":"10.1155/ijod/2351314","DOIUrl":"https://doi.org/10.1155/ijod/2351314","url":null,"abstract":"<p><p>Temporomandibular disorders (TMDs) can affect the stomatognathic system (SS) and alter tongue performance. This cross-sectional study aimed to evaluate tongue strength and its relationship with swallowing function in individuals diagnosed with TMD. Fifty adults participated (32 with TMD and 18 asymptomatic controls). TMD diagnosis was established according to the Diagnostic Criteria for TMDs (DC/TMD). Swallowing function was screened using the Eating Assessment Tool (EAT-10), and tongue strength was assessed using the Pro-Fono Lip and Tongue Pressure (PLTP) Biofeedback device. The sample had a mean age of 37.7 years and included 12 males and 38 females. Within the TMD group, 11 participants were diagnosed with myalgia, 8 with arthralgia, and 13 with both conditions. According to the EAT-10, 40 participants scored below 3, whereas 10 scored 3 or higher, indicating potential swallowing risk. Individuals with TMD exhibited significantly lower tongue strength in both the dorsum and tip compared with controls (<i>p</i> < 0.05). No significant differences were observed between sexes or age groups, and no associations were found between tongue strength and EAT-10 scores. Although self-perceived swallowing difficulties did not differ between groups, reduced tongue strength was observed in individuals with TMD, highlighting the importance of including objective tongue strength assessment in the clinical evaluation and management of these patients.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"2351314"},"PeriodicalIF":2.2,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13122724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Personalized Oral Health Education on Oral Hygiene Behavior and Periodontal Health: A Meta-Analysis and Systematic Review.","authors":"Yun Cai, Liping Wang, Raja Azman Raja Awang","doi":"10.1155/ijod/7955459","DOIUrl":"https://doi.org/10.1155/ijod/7955459","url":null,"abstract":"<p><strong>Aims: </strong>The benefits of personalized oral health education on periodontal health are still controversial. This study aims to systematically evaluate the impact of personalized oral health education on periodontal health in the general population through meta-analysis, and to provide evidence-based guidance for governments, medical institutions, and healthcare workers on implementing primary prevention of periodontal problems.</p><p><strong>Methods: </strong>We conducted a search of Chinese and English databases to identify relevant literature published from the inception of each database to December 31, 2023, regarding the impact of personalized oral health education on periodontal health in the general population. Randomized controlled trials that met our inclusion and exclusion criteria were collected, and a quality assessment of the literature was performed. The risk of bias was assessed using the Cochrane risk of bias tool Version 2.0. The meta-analysis was conducted using RevMan 5.4 and Stata 18.0 after the literature quality evaluation.</p><p><strong>Results: </strong>The search yielded 2690 articles. After rigorous screening, a total of eight papers were included, involving 3384 participants. The meta-analysis showed that personalized oral health education, compared with conventional methods, significantly decreased plaque index (PI) (mean difference [MD] = -0.42, 95% confidence interval [CI; -0.63, -0.21], <i>p</i> < 0.0001) and gingival index (GI) (MD = -0.47, 95% CI [-0.67, -0.27], <i>p</i> < 0.0001). It also enhanced self-efficacy and oral health-related quality of life. Moreover, it increased the frequency of toothbrushing and dental flossing, and improved oral health knowledge, attitude, and behavior among participants.</p><p><strong>Conclusion: </strong>This study suggests that personalized oral health education can significantly improve periodontal health.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"7955459"},"PeriodicalIF":2.2,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13121865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Midwifery Students' Knowledge and Need of Education Toward Oral Diseases in France.","authors":"Aikaterini Vasileiou, Lucie Brillaux, Catherine Petit, Pierre-Yves Gegout, Olivier Huck","doi":"10.1155/ijod/5058682","DOIUrl":"https://doi.org/10.1155/ijod/5058682","url":null,"abstract":"<p><strong>Introduction: </strong>Hormonal and immunological changes during pregnancy can affect oral health, especially periodontal conditions, which are linked to an increased risk of adverse pregnancy outcomes. This study aimed to evaluate the knowledge of midwifery students regarding oral diseases and their prevention during pregnancy.</p><p><strong>Materials and methods: </strong>A self-administered, structured questionnaire was sent to French midwifery students. It comprised 31 questions covering the demographic characteristics of the participants, knowledge of participants regarding the link between oral health and pregnancy, the consideration of oral health during their studies, and their clinical experience related to oral health in pregnant women. Descriptive analyses and univariate analyses were conducted.</p><p><strong>Results: </strong>A total of 420 students completed the questionnaire during the year 2024. Although 95% of those students acknowledged the importance of oral health during pregnancy, only 67% were aware of its link to adverse outcomes. Overall, 51% of the participants were aware of periodontitis, and only 8% recognized gingival diseases as a potential risk for pregnancy complications. Overall, 38% of the students considered themselves as insufficiently prepared to offer practical oral health advice, with only 2% providing regular counseling. There was a significant discrepancy in education toward periodontal diseases, with 43% of students reporting having lessons on the subject during their studies, mostly for less than 2 h.</p><p><strong>Conclusion: </strong>The level of students' knowledge and practice regarding oral health was not sufficient. Curricula improvements and increased clinical experiences are essential to enhance students' ability to assess oral health and provide preventive care to pregnant women. Future research should evaluate the effectiveness of these interventions.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"5058682"},"PeriodicalIF":2.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108240/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes of Keratinized Mucosa Width Around Posterior Implants: A Retrospective Cohort Study.","authors":"Ziyao Han, Yangeng Xu, Tao Xu, Cui Wang, Yiping Wei, Wenjie Hu, Kwok-Hung Chung, Yunsong Liu","doi":"10.1155/ijod/5801279","DOIUrl":"https://doi.org/10.1155/ijod/5801279","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the changes in keratinized mucosa width (KMW) at posterior implant sites through implant treatment procedures.</p><p><strong>Materials and methods: </strong>In this retrospective study, we measured the buccal KMW at three time points: immediately before implant placement (T0), before definitive prosthesis delivery (T1), and within 1 month after prosthesis delivery (T2). We analyzed changes in the KMW at the implant sites between these time points, using both submerged and non-submerged techniques.</p><p><strong>Results: </strong>A total of 72 patients and 98 implants were included. The KMW changed significantly from T0 to T1 (1.33 mm, 95% confidence interval [CI] [1.072, 1.561], <i>p</i> < 0.001) and from T0 to T2 (2.17 mm, 95% CI [1.929, 2.418], <i>p</i> < 0.001). No statistically significant differences were found in KMW changes between submerged and non-submerged implants from T0 to T1 (<i>p</i> = 0.556) or from T0 to T2 (<i>p</i> = 0.572). The height of the abutment was significantly related to the changes in KMW from T0 to T1 (-0.274 mm, 95% CI [-0.544, -0.004], <i>p</i> < 0.005), but implant technique, alveolar ridge preservation (ARP), and the diameter of the abutment were not (<i>p</i> > 0.05).</p><p><strong>Conclusion: </strong>The KMW at posterior implant sites decreased significantly through implant treatment procedures, which were related to the height of abutment, but not to implant technique, history of ARP, or the diameter of abutment.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"5801279"},"PeriodicalIF":2.2,"publicationDate":"2026-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13108585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lipopolysaccharides Modulate Cellular Responses in Dental Pulp Cells.","authors":"Tanida Srisuwan, Chatvadee Kornsuthisopon, Nunthawan Nowwarote, Xiaofei Zhu, Waruna Lakmal Dissanayaka, Thanaphum Osathanon","doi":"10.1155/ijod/2049490","DOIUrl":"https://doi.org/10.1155/ijod/2049490","url":null,"abstract":"<p><p>Lipopolysaccharide (LPS) triggers signal transduction in dental pulp cells (DPCs), leading to various biological events. The present study described the biological response of DPCs to LPS, aiming to provide a deeper understanding of its mechanisms. A literature search was performed in PubMed, Web of Science and Google Scholar using the keywords 'lipopolysaccharide', 'dental pulp cells' and 'dental pulp stem cells'. Original studies and review articles published in English that investigated cellular or molecular responses of pulp-derived cells to LPS stimulation were included. A narrative review was then conducted to summarise and discuss the effects of LPS on these cells. Across the selected studies, LPS exposure consistently activates intracellular signalling cascades in DPCs, leading to a series of downstream events, including inflammatory cytokine production, oxidative stress generation, mitochondrial impairment, premature cellular senescence and alterations in odonto/osteogenic differentiation. These interconnected molecular changes underpin the progression of pulpal inflammation and influence the tissue's capacity for repair or regeneration. This narrative review described the biological response of DPCs to LPS, providing deeper insight into its mechanisms. Understanding LPS-mediated signalling enables clinicians to tailor regenerative therapeutic approaches and vital pulp therapies by modulating inflammation and optimising biological events to support dental pulp tissue healing and dentine regeneration.</p>","PeriodicalId":13947,"journal":{"name":"International Journal of Dentistry","volume":"2026 ","pages":"2049490"},"PeriodicalIF":2.2,"publicationDate":"2026-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13106950/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}