International Journal of Diabetes and Endocrinology最新文献

{"title":"Semaglutide as an Antidiabetic Medication: A Summary of the Evidence from the Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes Clinical Trial Program","authors":"Gurdeep Singh, Matthew Krauthamer, Meghan Bjalme-Evans","doi":"10.11648/j.ijde.20210604.17","DOIUrl":"https://doi.org/10.11648/j.ijde.20210604.17","url":null,"abstract":"","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86953634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence of Type 2 Diabetes in the 27 Local Government Areas (LGAs) of Imo State","authors":"Nwaokoro Joakin Chidozie, Onwuliri Viola Adaku, Onyeocha O. Ignatius, Onwuliri Daniel Chinemerem, N. Johnkennedy, Ede Okorie Alison","doi":"10.11648/j.ijde.20210604.13","DOIUrl":"https://doi.org/10.11648/j.ijde.20210604.13","url":null,"abstract":"","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87281556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Incident Pattern and Trend of Type 2 Diabetes Among Adults in Akwa Ibom State, South-south Nigeria","authors":"C. Amadi, S. Onung, O. Ayoade, E. Abudu, Fabian Unyime, A. Usoro","doi":"10.11648/j.ijde.20210604.14","DOIUrl":"https://doi.org/10.11648/j.ijde.20210604.14","url":null,"abstract":"","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85428955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Biochemical Parameters at Presentation of Patients with Adrenal Insufficiency Attending a Tertiary Care Hospital","authors":"Rezwana Sobhan, Khan Mohammad Nazmus Saqeb, M. Ibrahim, Aleya Ferdush Monni, Mohammad Faruque Pathan, M. Ashrafuzzaman","doi":"10.11648/j.ijde.20210604.16","DOIUrl":"https://doi.org/10.11648/j.ijde.20210604.16","url":null,"abstract":"","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"240 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73964678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CASE REPORT-Delayed Cutaneous Manifestations of Graves’ disease, ADecade Post-Total Thyroidectomy","authors":"","doi":"10.36266/ijed/122e","DOIUrl":"https://doi.org/10.36266/ijed/122e","url":null,"abstract":"Pretibial myxoedema and thyroid acropachy are rare manifestations of Graves’ disease. Clinically, pretibial myxoedema is characterised by hyper-pigmented,asymmetrical, indurated non-pitting lesions of the lower limbs, whilst thyroidacropachy presents as digital clubbing and swelling of digits and toes. We describe a59-year-old female, who presents with pretibial myxoedema and thyroid acropachy,a decade post-thyroidectomy for Graves’ disease.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82394907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progressive Behavior Modification for Diabetes Patients Based on the GH-Math-Physical Medicine Method Along with the Psychological and Physiological Linkage Pattern Analysis","authors":"Gerald C. Hsu","doi":"10.46715/IJDE2020.06.1000105","DOIUrl":"https://doi.org/10.46715/IJDE2020.06.1000105","url":null,"abstract":"The author self-studied abnormal (traumatized) and behavior psychology for nine years and he also conducted his own research on endocrinology including chronic diseases, especially diabetes, for another nine years. \u0000\u00001.1. He has contemplated a specific question\u0000 \u0000“Why do some type 2 diabetes (T2D) patients choose to face serious complications, including death, rather than change their lifestyle in order to control their diabetic conditions?” \u0000\u00001.2. T2D patients have faced three major challenges\u0000\u00001.2.1. Availability of accurate disease information with either physical evidence or quantitative proof, not just some general qualitative descriptions that may include either false or commercial driven purpose over the internet (knowledge issue).\u0000\u00001.2.2. Awareness of disease status and then be able to overcome “self-denial” to move onto “psychological acceptance” state in order to take effective action. The most difficult barriers are having willpower, determination, and persistence on lifestyle change (psychology issues).\u0000\u00001.2.3. A non-invasive, effective, and ease-of-use artificial intelligence technology (AI) based tool to accurately predict outcomes and also guide patients (technology issue).\u0000\u0000His previous three specific papers in this area have already addressed the general understanding of the possible reasoning from a behavior psychology viewpoint by using wave theory, energy theory, frequency domain analysis (Fourier Transform), and segmentation pattern analysis. In those papers he also linked the patient’s psychological issues and diabetes physiological characteristics together in a mathematical and quantitative manner. \u0000\u0000From his T2D clinical cases, he was able to identify some of those patients’ key personality traits and psychological behavior patterns. In this paper, he further tries to offer a few practical “tips” in order to help diabetes patients to control their disease. He named his approach as the “Progressive Behavior Modification” which is also a part of the generalized “MPM: Mentality-Personality Modeling”.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74817840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Guesstimate Probable Partial Self-Recovery of Pancreatic Beta Cells Using Calculations of Annualized Glucose Data Using GH-Method: Math-Physical Medicine","authors":"Gerald C. Hsu","doi":"10.46715/ijde2020.05.1000103","DOIUrl":"https://doi.org/10.46715/ijde2020.05.1000103","url":null,"abstract":"In this paper, the author describes his hypothesis on the\u0000probable partial self-recovery of some insulin regeneration\u0000capability of pancreatic beta cells on a Type 2 Diabetes\u0000(T2D) patient via his collected data of both Postprandial\u0000Plasma Glucose (PPG) and Fasting Plasma Glucose (FPG)\u0000during the period of 1/1/2014 to 11/23/2019.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74114434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of urinary fibronectin and laminin as biomarkers of glomerular injury in diabetics in Port Harcourt, Nigeria","authors":"Michael Chinwe Orih, C. Obiorah","doi":"10.5897/jde2020.0137","DOIUrl":"https://doi.org/10.5897/jde2020.0137","url":null,"abstract":"About one-third of diabetes mellitus (DM) patients are complicated by diabetic nephropathy. It is even more challenging in type 2 DM in which this complication may occur before presentation. Microalbuminuria which is the traditional marker of early diabetic nephropathy is limited in its usefulness because it is detected when significant renal damage has already occurred. The aim of this study was to evaluate and compare urinary fibronectin and laminin with microalbuminuria as markers of glomerular injury in type 2 DM patients. A cross-sectional study with 120 consenting non-hypertensive type 2 DM, consisting of 57 (47.5%) males and 63 (52.5%) females; and 120 non-diabetic/non-hypertensive controls, consisting of 51 (42.5%) males and 69 (57.5%) females. Urinary albumin, fibronectin and laminin as well as plasma glucose were measured. The mean albumin –creatinine ratio was significantly higher (p<0.001) among type 2 DM (1.990.78 mg/mmol) compared to the control (0.120.01 mg/mmol). Also, urinary fibronectin (1.290.35 µg/mL) and laminin (1251.34+234.61 pg/mL) were significantly higher (p<0.001) in type 2 DM patients than in controls (0.290.07 µg/mL and 127.8114.07 pg/mL respectively). The sensitivity test for urinary fibronectin and laminin was 93.9% each while their specificities were 8.0 and 13.8% respectively. The negative predictive values (NPV) for urinary fibronectin and laminin were 77.8 and 85.7% respectively while the positive predictive values (PPV) were 27.9 and 29.2% respectively. This study suggests that assay for urinary fibronectin and laminin, which showed high sensitivities and high negative predictive values are useful as markers of early diabetic kidney disease and can substitute microalbuminuria in the routine evaluation of type 2 DM patients. The slightly higher PPV and NPV for urinary laminin suggest that it is a better marker than urinary fibronectin. \u0000 \u0000 Key words: Diabetes mellitus, microalbuminuria, urinary fibronectin, urinary laminin.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"48 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74912202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using A Comparison between Low-Carb and High-Carb Meals with A Detailed PPG\u0000Waveform Segmentation and Associated Energy Analysis to Investigate the Linkage\u0000between the Brain and Internal Organs (GH-Method: Math-Physical Medicine)","authors":"Gerald C. Hsu","doi":"10.46715/2020.05.1000102","DOIUrl":"https://doi.org/10.46715/2020.05.1000102","url":null,"abstract":"In this paper, the author analyzed his 1,707 meals that are\u0000segregated into low-carb and high-carb meals. The purpose\u0000is to attempt the validation of his hypothesis on the\u0000relationship from the directive of the brain to the\u0000gastrointestinal functions and liver’s glucose production\u0000capability by using PPG value changes over a smaller time\u0000segment (each segment with 15 minutes). The author uses\u0000the math-physical approach rather than a biochemical one","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74005182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Cognitive Survey on Diabetes and Periodontitis Among Endocrinologists and Diabetic Patients in Hainan Island","authors":"Xu Zheng, Chen Xie, Fu Tao Li, Rao Fu, Yu Zhi Wu, Yu Kun Shan, Ren Jie Zhao, Jing Tong Li, Q. Xie, Zhu-Ling Guo","doi":"10.11648/J.IJDE.20200502.11","DOIUrl":"https://doi.org/10.11648/J.IJDE.20200502.11","url":null,"abstract":"Objective: Periodontitis was linked to increased prevalence of diabetes and it is decisive to have a comprehensive cognition on the mutual influence for combined treatment. This study serves to provide accurate guidance data to endocrinologists and diabetic patients on periodontitis and diabetes. Materials and Methods: 50 endocrinologists and 200 diabetic patients were investigated in national public hospitals. Oral health habits, the cognition of diabetes and periodontitis were examined through questionnaires. Results: The cognitive level of diabetic patients on periodontitis and the correlation between periodontitis and diabetes was low. Only 48.6% patients agreed with \"Periodontitis may affect normal blood glucose level\". 86.2% patients were not clear that \"Treatment of periodontitis is beneficial to the prevention of diabetes\". 93.6% endocrinologists stressed that they were concerned about their patients' oral health, while only 23.6% patients received suggestions from their doctor on annual comprehensive periodontal evaluation. Conclusion: The cognition of the relationship between periodontitis and diabetes is deficient in public, represented by endocrinologists and diabetic patients in Hainan. Clinicians should strengthen the education on the bidirectional relationship between periodontitis and diabetes into their routine treatment and management.","PeriodicalId":13900,"journal":{"name":"International Journal of Diabetes and Endocrinology","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73210629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}