International Journal of Electrochemical Science最新文献

{"title":"Horseradish peroxidase biosensor based on a MWCNTs/black phosphorene nanocomposite for sensitive electrochemical detection of trichloroacetic acid and nitrite","authors":"Fan Shi ,&nbsp;Jiaqi Geng ,&nbsp;Baoli Wang ,&nbsp;Brij Mohan ,&nbsp;Wenhua Chen ,&nbsp;Yuxin Bi ,&nbsp;Lianjin Jiang ,&nbsp;Shu Deng ,&nbsp;Shengfen Wang ,&nbsp;Xiaoqing Li ,&nbsp;Wei Sun","doi":"10.1016/j.ijoes.2025.101126","DOIUrl":"10.1016/j.ijoes.2025.101126","url":null,"abstract":"<div><div>Developing electrochemical biosensors to detect trichloroacetic acid (TCA) and nitrite (NaNO₂) helps address serious health risks by improving electron transfer in the enzyme’s active center, enabling accurate monitoring of these harmful substances in environmental and food safety applications. Herein, a novel electrochemical horseradish peroxidase (HRP) biosensor was fabricated by immobilizing on a multi-walled carbon nanotubes-black phosphorene (MWCNTs-BP) nanocomposite modified carbon ionic liquid electrode. The structure and enzyme interaction were characterized using SEM, TEM, FT-IR, and UV-Vis spectroscopy. The MWCNTs-BP composite enhances electron transfer and interfacial conductivity, enabling efficient direct communication between HRP and the electrode. Under optimal conditions, the biosensor exhibited excellent sensitivity for TCA and NaNO₂ detection with linear ranges of 3.0–558.0 mmol/L (LOD as 1.0 mmol/L) and 0.1–13.6 mmol/L (LOD as 0.03 mmol/L), respectively. It was successfully applied to detect TCA and NaNO₂ in medical facial peel solutions and pickled vegetable soaking water samples, respectively, demonstrating strong practical applicability.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101126"},"PeriodicalIF":1.3,"publicationDate":"2025-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical determination of the ovarian cancer biomarker CA125 using TiO₂–ZnO nanocomposites","authors":"Wei Zhou,&nbsp;Kun Wang,&nbsp;Lipeng Pei","doi":"10.1016/j.ijoes.2025.101119","DOIUrl":"10.1016/j.ijoes.2025.101119","url":null,"abstract":"<div><div>Early and accurate detection of ovarian cancer is essential for improving patient outcomes, as most cases are diagnosed at an advanced stage. Cancer antigen 125 (CA125) is a clinically established biomarker that plays a critical role in the diagnosis, prognosis, and recurrence monitoring of epithelial ovarian carcinoma. This study presents a dual-channel electrochemical platform employing ZnO@TiO₂ nanotube arrays for the immunoanalysis of CA125 in complex biological matrices. The nanostructured electrode, fabricated through a sequential hydrothermal and annealing process, exhibited vertically aligned tubular morphology with a mean length of ∼2.5 µm and shell thickness of ∼20 nm. Electrochemical measurements leveraged dopamine and cytosine as reduction and oxidation probes, respectively, enabling orthogonal signal acquisition. Differential pulse voltammetry revealed wide linear response ranges: 0.1–1000 mU∙mL⁻¹ for cytosine (R² = 0.996; LOD = 0.0002 mU∙mL⁻¹) and 0.1–100 mU∙mL⁻¹ for dopamine (R² = 0.992; LOD = 0.0025 mU∙mL⁻¹). Impedance spectroscopy confirmed systematic resistance increases during antibody immobilization and antigen binding. The sensor demonstrated excellent reproducibility (RSD ≤ 8.9 %), signal stability over 30 days (≥89.1 % retention), and selectivity against six common interferents with &lt; 5 % deviation. Application in 0.2 % diluted serum showed recoveries from 99.6 % to 100.0 % and RSDs &lt; 2.01 %, validating its performance in real matrices. The combination of core–shell architecture, dual-probe mechanism, and surface regeneration capability positions this system as a promising diagnostic platform for clinical biosensing.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101119"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speciation analysis of Sb(III) and Sb(V) by adsorptive stripping voltammetry in the presence of Pyrogallol red","authors":"Fallon Rosales ,&nbsp;Juan José Triviño ,&nbsp;Carlos Rojas-Romo ,&nbsp;Claudia Núñez ,&nbsp;Verónica Arancibia","doi":"10.1016/j.ijoes.2025.101120","DOIUrl":"10.1016/j.ijoes.2025.101120","url":null,"abstract":"<div><div>This work presents an adsorptive stripping voltammetric method for the speciation of antimony based on the formation of their complexes with Pyrogallol red (PGR). Both Sb(III) and Sb(V) form complexes with PGR, however Sb(III) forms complex rapidly whereas Sb(V) forms complex very slowly. After the Sb^V-PGR complex is formed, on the surface of the mercury electrode is reduced to Sb^III-PGR. Then the electrochemical signal is the reduction of Sb^III-PGR complex to Sb(0). The variation of peak current with pH, accumulation time (t_acc), accumulation potential (E_acc), and PGR concentration (C_PGR) were optimized. The best experimental conditions for Sb(III) were pH: 2.2 (0.1 mol L⁻¹, Phosphate buffer, PB), C_PGR: 3.0 μmol L⁻¹, and E_acc: −0.10 V obtaining a detection limit (DL) of 1.1 μg L⁻¹ (t_acc: 35 s). When measured at 2 h, the signal of the Sb^III-PGR complex is almost the same and now it is possible to appreciate the increase in the signal due to presence of Sb^V-PGR complex, previously reduced to Sb^III-PGR in the Hg electrode. This allows us to determine the total concentration of antimony. The developed method was validated by the determination of Sb(III) in spiked drinking water from the laboratory and spiked synthetic seawater with relative errors of less than 5.0 %. The method was successfully applied to the determination of Sb(III) and Sb_total in an Industrial waste liquid sample comparing the results of Sb_total by ICP-OES technique (RE: 0.6 %).</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101120"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144596800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of nano-alumina electrodes in electrochemical sensing for monitoring exercise-induced lactate","authors":"Weicheng Gu","doi":"10.1016/j.ijoes.2025.101124","DOIUrl":"10.1016/j.ijoes.2025.101124","url":null,"abstract":"<div><div>This study reports the development of a novel potentiometric biosensor for non-invasive analysis of lactate in human sweat, employing a carbon paste electrode modified with nano-Al₂O₃ and lactate oxidase (LOx). Nano-Al₂O₃ was synthesized via a sol–gel process, yielding uniformly dispersed, porous particles with diameters of 80–90 nm and an average crystallite size of approximately 55 nm, which enhanced the electrode’s catalytic efficiency and electron transfer capabilities. The carbon paste electrode was prepared by incorporating 10 wt% of nano-Al₂O₃ into a composite of graphite and carbon black, followed by immobilization of LOx from a 2.5 mg/mL solution to ensure stable enzyme activity. Electrochemical evaluation revealed that the modification reduced the charge transfer resistance from 410 Ω for the bare electrode to 324 Ω, while the subsequent enzyme coating increased resistance moderately to 534 Ω without compromising performance. Calibration studies using lactate concentrations ranging from 0.1 mM to 50 mM yielded a linear response with a sensitivity of 150 mV per decade and a detection limit of 0.08 mM. The biosensor reached stable readings within 45–60 s and exhibited high reproducibility with a relative standard deviation below 4 % over repeated tests. <em>Ex vivo</em> sweat analysis during controlled exercise demonstrated a recovery rate of 96 % and a strong correlation (R² = 0.97) with standard HPLC measurements, verifying the biosensor’s real-world applicability. These results indicate that nano-scale modification via nano-Al₂O₃ integration significantly enhances biosensor performance, offering a promising platform for continuous metabolic monitoring in sports and clinical diagnostics.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101124"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144572819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of electrochemical sensors based on plasma-treated polymeric nanostructures for sensitive and reproducible detection of bisphenol A","authors":"Nageen Shoukat ,&nbsp;ChaeWon Mun ,&nbsp;Ho Sang Jung ,&nbsp;Min-Young Lee ,&nbsp;Soo Hyun Lee ,&nbsp;Sung-Gyu Park","doi":"10.1016/j.ijoes.2025.101121","DOIUrl":"10.1016/j.ijoes.2025.101121","url":null,"abstract":"<div><div>Significant public health concerns have been raised regarding humans' ubiquitous exposure to bisphenol A (BPA), an endocrine-disrupting chemical, through dietary and environmental pathways. In this study, for the sensitive detection of BPA, we developed three different electrochemical sensors (i.e., Au film, Au nanodimple (AuND), and Au nanopillar (AuNP)) and investigated the influence of electroactive surface area on electrochemical sensing performance. The supporting polymeric nanostructures (i.e., NDs and NPs) were developed using facile plasma treatment processes. Cyclic voltammetry and electrochemical impedance spectroscopy were used to evaluate the electrodes' electroactivity. Compared with the other electrode materials (i.e., Au film and AuNDs), the AuNPs, which exhibited a high density and high aspect ratio, showed excellent redox behaviors and low charge transfer resistance. A quantitative investigation of BPA was conducted using differential pulse voltammetry. Under optimal experimental conditions, the AuNP sensors demonstrated a linear response (<em>R</em>² = 0.98), nanomolar sensitivity, and high reproducibility (relative standard deviation ≤ 3.1 %) in the dynamic BPA concentration range from 2 to 1000 nM. The viability of the AuNP sensors in practical applications was also examined with BPA-spiked artificial tear and urine samples. The results highlight that the electrochemical sensors implanted with AuNP platforms are suitable for monitoring BPA in contaminated water and biofluids.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101121"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144570152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2D material-based electrochemical sensors for early diabetes detection: A review of progress and prospects","authors":"Ming Yang ,&nbsp;Dongting Fu ,&nbsp;Chunlei Gao ,&nbsp;Ying Liu","doi":"10.1016/j.ijoes.2025.101123","DOIUrl":"10.1016/j.ijoes.2025.101123","url":null,"abstract":"<div><div>Diabetes mellitus represents a significant and escalating global health challenge, characterized by alarming prevalence rates and substantial economic burden. Early detection is paramount for effective management and prevention of debilitating long-term complications, yet conventional diagnostic methods face limitations in terms of accuracy, convenience, cost, and ability to capture dynamic glycemic changes. Electrochemical biosensors offer a promising alternative, providing advantages such as high sensitivity, rapid response, portability, and potential for miniaturization. The advent of two-dimensional (2D) materials, including graphene, transition metal dichalcogenides (TMDs), and MXenes, has revolutionized the field of electrochemical sensing. Their unique physicochemical properties—including high electrical conductivity for rapid electron transfer, large surface area for enhanced analyte interaction, tunable surface functionalization for bioreceptor immobilization, and mechanical flexibility for wearable integration—enable substantial improvements in sensitivity, selectivity, and operational stability of electrochemical sensors. This review provides a comprehensive overview of the progress in utilizing 2D material-enhanced electrochemical sensors for the early detection of key diabetes-related biomarkers, including glucose, glycated hemoglobin (HbA1c), insulin, glucagon, and ketones. We discuss the fundamental properties of these 2D materials and the mechanisms by which they improve sensor sensitivity, selectivity, and stability. Recent advancements in sensor design, fabrication strategies, and performance metrics (limit of detection, linear range, response time) are critically examined, along with validation studies in relevant biological matrices. Despite considerable progress, challenges remain concerning material synthesis reproducibility, long-term stability in biological environments, susceptibility to biofouling and interference, and pathways towards cost-effective, scalable manufacturing and clinical translation. Future prospects, including the exploration of novel 2D materials and heterostructures, advanced functionalization techniques, multiplexed detection platforms, and integration into wearable and point-of-care systems, are discussed. Addressing the current hurdles will be crucial for realizing the full potential of 2D material-based electrochemical sensors in transforming diabetes diagnostics and management.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101123"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144580737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Novel green approach for the synthesis of highly conductive graphene/MoS₂ composites","authors":"Xin Wang,&nbsp;Xiaolong Wang","doi":"10.1016/j.ijoes.2025.101122","DOIUrl":"10.1016/j.ijoes.2025.101122","url":null,"abstract":"<div><div>To address the inherent low conductivity of MoS₂, we developed a novel, simple, green, and scalable method for the preparation of graphene/MoS₂ composites using a laboratory-designed system. Through systematic optimization, the optimal preparation conditions were determined. Moreover, this method differs from traditional approaches that require high temperatures or hazardous reagents by enabling simultaneous exfoliation and compositing under mild conditions. Thus offering significant environmental and practical advantages. Comprehensive structural characterizations were conducted using XRD, Raman, SEM, TEM, HRTEM, and XPS. The results confirmed that bulk MoS₂ and graphite were successfully exfoliated into few-layer MoS₂ and graphene, respectively, which were subsequently composited to form a stable graphene/MoS₂ composite. The resulting material shows significantly enhanced electrical conductivity and charge transport, attributed to microstructure optimization and interfacial synergy. Overall, this study provides a practical and environmentally friendly strategy for improving the electrical conductivity of MoS₂, with promising potential for scalable production.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101122"},"PeriodicalIF":1.3,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144571270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gold nanoparticles-decorated graphynes for electrochemical detection of vitexin","authors":"Lihong Ma ,&nbsp;Yufang Huang ,&nbsp;Qiaowen Huang ,&nbsp;Junyong Han ,&nbsp;Wei Li ,&nbsp;Hongxu Liu ,&nbsp;Chuan Jiang ,&nbsp;Huiqing Que","doi":"10.1016/j.ijoes.2025.101118","DOIUrl":"10.1016/j.ijoes.2025.101118","url":null,"abstract":"<div><div>Vitexin is an important bioactive flavonoid with superior pharmacological value. Herein, by preparing graphynes decorated with gold nanoparticles (Au/GDY) as electrode material via a facile electroless deposition method, a sensitive electrochemical sensor was proposed to detect vitexin for the first time based on Au/GDY hybrid modified glassy carbon electrode (Au/GDY/GCE). The Au/GDY hybrid nanomaterial could capitalize on the synergistic effects of (i) GDY's π-electron-rich structure which is beneficial to enhance the target affinity through π-π stacking, and (ii) Au' dual functionality as conductivity boosters and catalytic activators. The related electrochemical evaluations revealed that the as-proposed Au/GDY/GCE exhibits much superior sensing performances compared to GDY/GCE and bare GCE for vitexin, achieving a broad linear range (0.05 – 4.0 μM) and a low detection limit (15.0 nM). In addition, the as-designed sensor also demonstrated exceptional reproducibility, long-term stability and selectivity for vitexin detection, showing significant potential application.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101118"},"PeriodicalIF":1.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of graphene concentration on mechanical properties of electrodeposited Al-Graphene composite coating","authors":"Na Li ,&nbsp;Qiao Li ,&nbsp;Yongchao Zhu ,&nbsp;Huizhong Ma ,&nbsp;Lan Zhang","doi":"10.1016/j.ijoes.2025.101117","DOIUrl":"10.1016/j.ijoes.2025.101117","url":null,"abstract":"<div><div>To enhance the surface hardness and strength of aluminum alloys and achieve low-temperature synthesis of aluminum-graphene composite materials, Al-Graphene composite coatings are electrodeposited on the 7075-aluminum alloy substrate from organic solvent solution system at 25 ℃ containing different graphene concentration. The morphology, microstructure and mechanical properties of Al-Graphene composite coating were characterized and reconnoitered. Al-Graphene composite coatings exhibit improved performance significantly. Under the optimal graphene concentration of 7 g L⁻¹, Al-Graphene shows 5.1-times increase in hardness in comparison with pure Al coating. The elastic modulus has the peak value of 84.4 GPa for Al-Graphene containing 10.64 wt% graphene, which has an increment of 66.2 % compared with pure Al coating. These put down to the remarkable mechanical property of graphene. Moreover, the content and distribution of graphene play a key role in the mechanical properties of Al-Graphene. The alternating well-dispersed graphene and reduced metal layer, simultaneously keep appropriate thickness of reduced metal layer is able to achieve the optimal comprehensive mechanical property, which exhibits promising application potential in aircraft skins, automotive components, and related fields.</div></div>","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 10","pages":"Article 101117"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144524309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “Automated electrochemical milling of complex surfaces with integrated path planning and gap control strategy” [Int. J. Electrochem. Sci. 20 (6) (2025) 101011]","authors":"Ming Fang ,&nbsp;Liangliang Hou ,&nbsp;Xu Cheng ,&nbsp;Junlong Wang ,&nbsp;Shenao Ma ,&nbsp;Pujie Zhang","doi":"10.1016/j.ijoes.2025.101106","DOIUrl":"10.1016/j.ijoes.2025.101106","url":null,"abstract":"","PeriodicalId":13872,"journal":{"name":"International Journal of Electrochemical Science","volume":"20 9","pages":"Article 101106"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144714499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}