International Journal of Biomedical and Advance Research最新文献_第8页

Rudimentary horn of Uterus : A diagnostic challenge in pregnancy 子宫初生角:妊娠诊断的挑战

International Journal of Biomedical and Advance Research Pub Date : 2017-09-30 DOI: 10.7439/IJBAR.V8I9.4406

Shreeji Goyal, A. Mahajan, Shreeya Goyal

引用次数: 1

Clinical study of post-inflammatory hypopigmented macular skin lesions 炎症后低色素黄斑皮肤病变的临床研究

International Journal of Biomedical and Advance Research Pub Date : 2017-09-29 DOI: 10.7439/ijbar.v8i9.4389

Yoganand J. Phulari

{"title":"Clinical study of post-inflammatory hypopigmented macular skin lesions","authors":"Yoganand J. Phulari","doi":"10.7439/ijbar.v8i9.4389","DOIUrl":"https://doi.org/10.7439/ijbar.v8i9.4389","url":null,"abstract":"Hypopigmented lesions of the skin constitute one of the important problems in dermatologic practice. Study was conducted with objective to study different clinical presentations of post-inflammatory hypopigmented macules, age and sex distribution, socioeconomic status, natural course, seasonal incidence, commonest to rarest variant amongst all etiologies and to do a detailed histopathological study of such lesions. 100 patients presenting with post-inflammatory hypopigmented macules were considered and detailed history and general examination was done. Certain specific Lab investigations and histopathological study was done in selected cases. The study showed amongst all varied etiologies of post-inflammatory hypopigmentation, commonly observed in dermatologic practice were Tinea Versicolor, Leprosy, Pityriasis Alba, Mechanical and thermal injuries, Allergic contact dermatitis, Morphoea, Discoid lupus erythematosus, Stevens Johnson syndrome and Psoriasis. Commonest age group affected was in 21-30 years of age. Males (62%) outnumbered females (38%) grossly. People of lower socioeconomic status (57%) presented with post-inflammatory hypopigmentation, commonly. Upper limbs and face and neck region were the commonest sites involved. Commonest etiology amongst all cases was Tinea Versicolor, followed by Leprosy, Pityriasis Alba and thermal burns. The study concludes that post-inflammatory hypopigmentation is a self limiting disease, presenting with varied clinical manifestations, more common in young adults with male preponderance, commonly seen in people of lower socioeconomic group with a family history of similar disease in not more than 30%. Upper limbs and face and neck is the commonest sites of involvement and histopathological diagnosis correlates well with clinical study in most of the cases.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"39 1","pages":"355-358"},"PeriodicalIF":0.0,"publicationDate":"2017-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78559945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Immunomodulatory Potential Of Rutin And Quercetin In Swiss Mice Exposed To Gamma Radiation 芦丁和槲皮素对γ辐射下瑞士小鼠的免疫调节作用

International Journal of Biomedical and Advance Research Pub Date : 2017-08-30 DOI: 10.7439/IJBAR.V8I8.4297

S. Patil, Shilpa Patil, Nageshwara B. Rao, H. Somashekarappa

引用次数: 0

Serum B12 Levels in Type II Diabetics on Metformin Therapy and its association with Clinical Neuropathy 二甲双胍治疗的II型糖尿病患者血清B12水平及其与临床神经病变的关系

International Journal of Biomedical and Advance Research Pub Date : 2017-08-30 DOI: 10.7439/IJBAR.V8I8.4356

H. M.P., M. Vyawahare, K. Shekar

{"title":"Serum B12 Levels in Type II Diabetics on Metformin Therapy and its association with Clinical Neuropathy","authors":"H. M.P., M. Vyawahare, K. Shekar","doi":"10.7439/IJBAR.V8I8.4356","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I8.4356","url":null,"abstract":"Background: Metformin use in type II DM has also been known to cause B12 deficiency in as reported many studies. Iatrogenic neuropathy caused by Metformin induced B12 deficiency can add to burden of peripheral neuropathy that already exists in diabetic patients. Aims and Objectives: 1)To determine the serum vitamin B12 levels in patients of type II DM on metformin therapy and compare it with those not on metformin therapy; 2) To correlate serum vitamin B12 levels with dose and duration of metformin therapy; 3) To investigate association between peripheral neuropathy and serum vitamin B12 levels. Method: The present two year hospital based cross sectional study enrolled total 132 cases of type 2 diabetes mellitus and divided into two groups, (metformin group 70 and non-metformin group 62). Serum vitamin B12 levels were measured in all patients. Toronto clinical scoring system (TCSS) and nerve conduction velocity (NCV) tests were used to assess peripheral neuropathy. The correlations of vitamin B12 levels with Toronto clinical score, nerve conduction studies, cumulative dose and duration of metformin therapy was done. Results: The serum vitamin B12 levels were significantly lower in patients who consumed metformin (292.64 152.82 pg/ml) as compared to non-metformin, (406.91 126.59 pg/ml) group. There was a significant negative correlation of serum vitamin B12 levels with cumulative dose and duration of metformin therapy. The incidence of neuropathy by TCSS and NCV test was significantly higher in metformin group with a positive correlation with cumulative dose and duration of metformin and a negative correlation with serum vitamin B12 levels. Conclusion: Metformin use is significantly associated with decrease in vitamin B12 levels and increased incidence of neuropathy, this is dependent on dose and duration of metformin therapy.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"1 1","pages":"321-326"},"PeriodicalIF":0.0,"publicationDate":"2017-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89053687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

A prospective observational study to predict difficult intubation using simple non-invasive tests 一项前瞻性观察研究预测插管困难使用简单的非侵入性测试

International Journal of Biomedical and Advance Research Pub Date : 2017-08-30 DOI: 10.7439/ijbar.v8i8.4355

Sunita Sanklecha, Jyotsna Mali

{"title":"A prospective observational study to predict difficult intubation using simple non-invasive tests","authors":"Sunita Sanklecha, Jyotsna Mali","doi":"10.7439/ijbar.v8i8.4355","DOIUrl":"https://doi.org/10.7439/ijbar.v8i8.4355","url":null,"abstract":"Introduction: Airway assessment is the first step in successful airway management. Several anatomical and functional maneuvers can be performed to estimate the difficulty of endotracheal intubation. We aimed to elucidate the role of upper lip bite test (ULBT), hyomental/thyrosternal (HMD/TSD) distances, the mandible length (ML) and their correlation in predicting difficulty intubation in relation to laryngoscopic view as per Cormack Lehane (CL) grading. Methods: After institutional approval informed consent obtained from160 consecutive patients aged between 20 to 60 years of ASA grading I and II scheduled for elective surgical procedures requiring tracheal intubation and meeting the inclusion criteria were enrolled in this study. Each patient was evaluated regarding ULBT, HMD, TSD, ML. Larngoscopy was assessed and findings were graded according to Cormack and Lehane's grading system. Results: The above study states the Negative Predictive Value (NPV) and Positive Predictive Value (PPV) of ULBT were found to be 86.7% and 94.5% respectively. Specificities of ULBT, HMD, TSD and ML were found to be 98.6%, 97.8%, 96.4% and 97.8% respectively. Diagnostic accuracy of ULBT, HMD, TSD, ML were found to be 93.8% ,88.1% ,84.4% and 91.3% respectively. Conclusion: It concludes that high specificity, NPV, PPV and Accuracy of ULBT as revealed in this study could be good rationale for its application in the prediction of difficulty or easiness in the intubation.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"23 1","pages":"318-320"},"PeriodicalIF":0.0,"publicationDate":"2017-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90194645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of right ventricular function in patients with complete right bundle branch block with normal structural heart 正常结构心脏完全性右束支传导阻滞患者右心室功能的评价

International Journal of Biomedical and Advance Research Pub Date : 2017-08-30 DOI: 10.7439/IJBAR.V8I8.4302

G. Kavi, A. Mishra, M. Kapoor, A. Malviya, Sakshi Sharma, Tony Ete, Rinchin Dorjee, C. Das

{"title":"Evaluation of right ventricular function in patients with complete right bundle branch block with normal structural heart","authors":"G. Kavi, A. Mishra, M. Kapoor, A. Malviya, Sakshi Sharma, Tony Ete, Rinchin Dorjee, C. Das","doi":"10.7439/IJBAR.V8I8.4302","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I8.4302","url":null,"abstract":"Background: The impact of a RBBB in cases with structural heart disease on cardiac function has been evaluated extensively. However, literature about the impact of an isolated complete RBBB without structural heart disease on cardiac function of the right ventricle is limited. Aim: To assess right ventricular function in patients with complete RBBB in normal structural heart patients Material and Methods: Hospital based observational study in 100 patients aged ? 18 years. Cases (50) consisted of patients with isolated complete right bundle branch blocks without structural heart disease while the control group consisted of 50 healthy adults. The diameter, end-diastolic area, end-systolic area, and right ventricular (RV) fractional area ,pulse wave tissue velocity at lateral tricuspid annulus ,TAPSE and E/A ratio were obtained to evaluate RV morphologic and systolic and diastolic function . Results : Although ,the measurements of RA area ,RV basal dimension , RV fractional area change ,TAPSE ,RIMP and S' at lateral tricuspid tissue annulus were in normal limits in block group but there was statistical significant difference in between the patients with blocks and controls(p <0.05 ) . The myocardial performance index (Tei index) of the lateral tricuspid tissue annulus was significantly increased. Chi square test and t test was applied to compare the same variable between the group and p value of ? .05 was considered statistically significant. Conclusions : In patients with isolated complete right bundle branch blocks, systolic and diastolic functions are impaired in the RV and follow-up is needed.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"54 1","pages":"307-309"},"PeriodicalIF":0.0,"publicationDate":"2017-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75422212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Histopathology of soft tissue tumors in association with immunohistochemistry 软组织肿瘤的组织病理学与免疫组织化学的关系

International Journal of Biomedical and Advance Research Pub Date : 2017-08-29 DOI: 10.7439/ijbar.v8i8.4304

Sonal Jain, Kirit Jadav

{"title":"Histopathology of soft tissue tumors in association with immunohistochemistry","authors":"Sonal Jain, Kirit Jadav","doi":"10.7439/ijbar.v8i8.4304","DOIUrl":"https://doi.org/10.7439/ijbar.v8i8.4304","url":null,"abstract":"Aim: To study the histopathological pattern for understanding the classification and type of soft tissue tumors. To find out the relative incidence of benign and malignant soft tissue tumors and to classify the soft tissue tumours on basis of age, sex, site, types and benign and malignant behaviour. Material and Methods: The test population comprised of patients with soft tissue lesions, between July 2014 to July 2016, evaluated by light microscopy and Immunohistochemistry. Results: Painless mass was the most common presenting symptom in our study. Benign soft tissue tumors (89.7%) outnumbered malignant tumors (9.2%) by a ratio of 9.7:1. In our study, Male: Female ratio-1.16:1. In benign soft tissue tumor, Male: Female ratio -1.1:1 and in malignant soft tissue tumor, Male: Female - 0.9:1 in our study. First most common soft tissue tumors are Lipomatous tumors among the all soft tissue tumor. Benign lipomatous tumors are the most common tumors in present study. Most common site soft tissue tumor found is upper limb with chest in present study. Most common age of soft tissue tumor is in 2 nd and 3 rd decade of life. Malignant tumors are 9.2% reported; most common tumors are skeletal muscle tumors 100% followed by stromal tumor (80%). Second most common tumor is capillary lobular haemangioma which are of vascular origin. In the present study 3 cases of intermediate type of soft tissue tumor 2 of haemangiopericytoma and 1 of fibromatosis are found, which are rarely found. IHC markers were applied in 25 cases where microscopy was inconclusive to arrive at a definite diagnosis. Conclusion: A good clinical acumen, through description and grossing of specimen, and microscopic evaluation of hematoxylin and eosin stained sections are fundamental aspects in diagnosis of soft tissue tumors. Majority of tumors diagnosed by hematoxylin and eosin stained sections. Immunohistochemistry was done wherever light microscopy was inconclusive.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"32 1","pages":"327-336"},"PeriodicalIF":0.0,"publicationDate":"2017-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77922447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Study of subcutaneous fat, BMI in diabetic and non-diabetic adolescents 糖尿病和非糖尿病青少年皮下脂肪、BMI的研究

International Journal of Biomedical and Advance Research Pub Date : 2017-08-29 DOI: 10.7439/IJBAR.V8I8.4339

Jagdish Vishnoi, B. S. Bomb, K. Babu

{"title":"Study of subcutaneous fat, BMI in diabetic and non-diabetic adolescents","authors":"Jagdish Vishnoi, B. S. Bomb, K. Babu","doi":"10.7439/IJBAR.V8I8.4339","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I8.4339","url":null,"abstract":"Introduction: Diabetes is a Metabolic Disorder which has got prime focus in the present days. An increase in body fat is generally associated with an increase in risk of metabolic diseases such as type 2 diabetes mellitus, hypertension and dyslipidaemia. Prevalence of childhood and adolescent obesity is further adding the severity. Therefore, any measures that could prevent or delay the development of diabetes are urgently needed. The present study is focused on early detection of the occurrence of Diabetes so that its control can be more effective because of early intervention. Materials & Methods: 50 people with increased blood sugar levels of age group of 16-20 years of both the sexes are selected randomly as subjects and 50 people with normal blood sugar levels are randomly selected as control group . Primary data of all the subjects like name, age, sex, occupation, address etc., are obtained as per the proforma. Calculation of Body Fat Percentage (%BF) involves measuring of skin fold thickness at four sites. Body Mass Index (BMI) calculated from Height and Weight of an individual. Results: The mean value of BMI in Diabetic group is found be 25.64Kg/m 2 (SD 2.22), while in Non-Diabetic group it is found to be 23.35Kg/m 2 (SD 3.95). The mean value of %BF in Diabetic group is 18.20 (SD 1.62), while in Non-Diabetic group it is found to be 17.36 (SD 1.41). The mean values of RBS in Diabetic group are found be 157.98mg/dl (SD 30.37) and 120.66mg/dl (SD 21.44) in Non-Diabetic group. Discussion: In the present study, we observed the correlation of increased subcutaneous fat with increased plasma glucose levels. Increased subcutaneous fat is considered to be an aggravating factor for early development of diabetes. Increased subcutaneous fat is also responsible for increasing the severity of diabetes there by, worsening the condition of the person. By knowing the body subcutaneous fat, the chances of occurrence of diabetes can be known.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"2 2 1","pages":"337-340"},"PeriodicalIF":0.0,"publicationDate":"2017-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83490806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perceptions and adoption of male contraceptives among men in Indonesia 印度尼西亚男性对男性避孕药具的认知和采用

International Journal of Biomedical and Advance Research Pub Date : 2017-08-02 DOI: 10.7439/IJBAR.V8I7.4290

S. Haryanto

{"title":"Perceptions and adoption of male contraceptives among men in Indonesia","authors":"S. Haryanto","doi":"10.7439/IJBAR.V8I7.4290","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4290","url":null,"abstract":"Introduction : The Family Planning program implemented in Indonesia in the 1970s successfully increases the prevalence of contraception, and on the other hand, lowers fertility. Nevertheless, this success is marred by gender inequality. The majority of family planning acceptors are women. Method : The study (1) explores male narratives on male contraceptives and male perceptions of their risks and benefits; (2) identifies the factors affecting male decisions about contraception; and (3) shows how men negotiate and discuss contraception with women if at all before making decisions. The study was conducted in Bandar Lampung (Lampung) and Kulon Progo (Special Region of Yogyakarta). A total of 30 participants, consisting of married men who received a vasectomy, married men who used condoms, sexually active unmarried men who used condoms, and married men who did not use contraceptives were interviewed in depth. In addition, focus group discussions (FGD) were conducted involving stakeholders in each region. Results: That men who used contraceptives experienced positive changes after receiving information and support from their peer group. Men who use contraceptives start off with views (myths) similar to those of the surrounding communities. Gender equality perspective was a key factor affecting contraceptive decision-making among men. Discussion: that male perception of male contraceptives, especially vasectomy, is in flux. Negative prior to use, it gradually transforms into positive after men experience the benefits. Male decisions to use contraceptives are determined by their perceptions .","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"43 1","pages":"292-299"},"PeriodicalIF":0.0,"publicationDate":"2017-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74150867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Anatomical study of high bifurcation of common carotid artery in human cadavers 人颈总动脉高分叉的解剖研究

International Journal of Biomedical and Advance Research Pub Date : 2017-08-01 DOI: 10.7439/IJBAR.V8I7.4331

Prashant Munjamkar, Anil Sahebrao Pungle, N. Kamdi

引用次数: 0