International Journal of Biomedical and Advance Research最新文献_第9页

Evaluation of thyroid profile status in women with abnormal uterine bleeding in north Indian population 北印度人群子宫异常出血妇女甲状腺特征状态的评价

International Journal of Biomedical and Advance Research Pub Date : 2017-08-01 DOI: 10.7439/IJBAR.V8I7.4291

M. Parveen, S. Kumari, S. Haque, Ravi Kumar

{"title":"Evaluation of thyroid profile status in women with abnormal uterine bleeding in north Indian population","authors":"M. Parveen, S. Kumari, S. Haque, Ravi Kumar","doi":"10.7439/IJBAR.V8I7.4291","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4291","url":null,"abstract":"Background: Abnormal Uterine Bleeding is a common complication occurs in 9 14% of women from Menarche to Menopause. Women are more prone to thyroid disorder and cause abnormal sexual development, menstrual irregularity, infertility and premature menopauseMy objective of studyis to evaluate the thyroid function tests in women with abnormal uterine bleeding in north Indian population. Methods: After selecting the women, informed consent was obtained. The case history and clinical examination of them were done, requested to do thyroid functioning test in fasting status in early morning and the results were evaluated. Thyroid function tests were estimated by Chemiluminescence Immuno Assay (C.L.I.A) method using reagent Monobind I N C with the help of fully automatic Elecsys 2010 machine made by ROCHE. Results: There were 150 women who were included in the study. Out of all the types of commonest symptoms were menorrhagia. around 47%. Patients with oligomennorrhoea had hyperthyroidism in 16.7% of patients, hypothyroidism in 8.3% of patients and subclinical hypothyroidism in 8.3%. In polymenorrhoea patients 42.9% of cases had subclinical hypothyroidism. Conclusions: As there is high incidence of thyroid diseases in a north Indian population, women with abnormal uterine bleeding. This would also avoid unnecessary hormonal treatment and surgical intervention in these patients.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"387 1","pages":"288-291"},"PeriodicalIF":0.0,"publicationDate":"2017-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80793163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Mobile charger cable in bladder- A Case Report 膀胱内移动充电器电缆1例报告

International Journal of Biomedical and Advance Research Pub Date : 2017-07-30 DOI: 10.7439/IJBAR.V8I7.4283

M. Dhotre, Vinayak N. Tukka, B. H. Revanasiddapa, Jaya Datta Pawar

引用次数: 1

Effects of subcranial myofascial distraction and condylar remodeling exercises on temporomandibular disability index score in patients with temporomandibular joint disorders 颅下肌筋膜牵张和髁重构运动对颞下颌关节障碍患者颞下颌残疾指数评分的影响

International Journal of Biomedical and Advance Research Pub Date : 2017-07-30 DOI: 10.7439/ijbar.v8i7.4238

Shilpa Chourasia, P. Deshmukh, Rahi Wankar

{"title":"Effects of subcranial myofascial distraction and condylar remodeling exercises on temporomandibular disability index score in patients with temporomandibular joint disorders","authors":"Shilpa Chourasia, P. Deshmukh, Rahi Wankar","doi":"10.7439/ijbar.v8i7.4238","DOIUrl":"https://doi.org/10.7439/ijbar.v8i7.4238","url":null,"abstract":"Background : The patients with temporomandibular joint disorders will be likely to benefit from combination of subcranial myofascial distraction and condylar remodeling exercises. Aim of the study- To study effects of subcranial myofascial distraction and condylar remodeling exercises in patients with temporomandibular joint disorders. Methods: A randomized control trial, in which 120 patients were selected using block randomisation method, was carried out. They were divided into 3 groups of 40 each, Group A- subcranial myofascial distraction, Group B- combination of subcranial myofascial distraction and condylar remodeling exercises, Group C- condylar remodeling exercises alone. These patients were assessed for outcome measure i.e. temporomandibular disability index score. The frequency of therapeutic protocol for subcranial myofascial distraction was 3 repetitions of 90 seconds hold period each, rest period of 60 seconds between two repetitions. This intervention was given for 6 days/week for 2 weeks. Every exercise in condylar remodeling exercises was performed 6 times in one session under the supervision of physiotherapist and same session was performed at home by the patient preferably in evening for 6 days/week for 2 weeks. Results: The data was analyzed using one way ANOVA, repeated measure ANOVA, Kruskal Wallis Non parametric ANOVA test. Patients receiving a combination of subcranial myofascial distraction and condylar remodeling exercises (Group B) showed greater improvement compared to other two groups (Group C and A ). Conclusion: Subcranial myofascial distraction and condylar remodeling exercises help in decreasing disability associated with temporomandibular joint disorder.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"66 1","pages":"264-269"},"PeriodicalIF":0.0,"publicationDate":"2017-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87613896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The efficacy & safety of paracervical block with conscious sedation in surgical evacuation of early pregnancy 宫颈旁阻滞加清醒镇静在早孕手术撤离中的有效性和安全性

International Journal of Biomedical and Advance Research Pub Date : 2017-07-30 DOI: 10.7439/IJBAR.V8I7.4226

Ashish Vadhera, Sanjaya Sharma, M. Dey

{"title":"The efficacy & safety of paracervical block with conscious sedation in surgical evacuation of early pregnancy","authors":"Ashish Vadhera, Sanjaya Sharma, M. Dey","doi":"10.7439/IJBAR.V8I7.4226","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4226","url":null,"abstract":"Background: Regional anesthesia is an easy, safe and has much less complications than General anesthesia especially in minor surgical procedures. This study is done to assess the safety & feasibility of Paracervical Block with conscious sedation in surgical evacuation of early pregnancy. Materials & methods: Our study was a prospective observational study carried out in a tertiary care teaching center in Pune. Total of 119 patients were included in the study who had undergone surgical evacuation of first trimester pregnancy between Aug 2014 to July 2016. Patients were given 10 ml of Lignocaine 2% in paracervical block & Inj Midazolam 0.04mg/Kg body wt. and Inj Fentanyl 0.002mg/Kg for conscious sedation. Primary outcome includes success of the procedure as assessed by the patients. Results: The opinion of the patients immediately after and 24 hrs after the surgery has shown that 97.5% of our patient have accepted the technique. The vital parameters were quite stable in both intra operative and post operative period as compared to its pre operative values. Our technique in the study was well tolerated by most of the patients with only 5.8% patients had minor and non serious side effects. It is clearly evident by about 3 hours of procedure patients were back to normal pre operative state. Conclusion: Paracervical block with conscious sedation is an effective and safe method for surgical evacuation of early pregnancy.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"16 1","pages":"279-283"},"PeriodicalIF":0.0,"publicationDate":"2017-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83381631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Hypolipidemic Activity of of Madhuca longifolia in Triton Induced Hyperlipidemic Rats 长叶麻对Triton诱导的高脂血症大鼠降血脂活性的影响

International Journal of Biomedical and Advance Research Pub Date : 2017-07-28 DOI: 10.7439/IJBAR.V8I7.4157

A. Shrirao, N. Kochar, A. Chandewar

{"title":"Hypolipidemic Activity of of Madhuca longifolia in Triton Induced Hyperlipidemic Rats","authors":"A. Shrirao, N. Kochar, A. Chandewar","doi":"10.7439/IJBAR.V8I7.4157","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4157","url":null,"abstract":"Objective: In the present study, an aqueous extract from Madhuca longifolia bark was evaluated for its hypocholesterolaemic and hypotriglyceridaemic activities using Triton WR-1339 induced hyperlipemic rats as experimental model. Material and Method: Hyperlipidemia was induced by a single injection of Triton WR 1339 (400 mg/kg i.p.) in sprauge dawley rats. Aqueous extract of Madhuca longifolia bark (ML) (250, 500 and 750 mg/kg/day) was administered to hyperlipidemic rats for one week. Harvested serum was analyzed for lipid profile such as cholesterol, triglyceride, and lipoproteins. Oxidative stress parameters like Superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPx) and Glutathione reductase (GRh) and activity of lipolytic enzyme such as lecithincholesterol-acyltransferase (LCAT) & post-heparin lipolytic activity (PHLA) were estimated in the liver tissues of hyperlipidemic rats. Results: Result of the study suggested that treatment with ML 750mg/kg/day significantly (p?0.01) lowered the level of serum cholesterol, triglyceride phospholipids and increased in lecithincholesterol-acyltransferase activity & post-heparin lipolytic activity compared to Triton-treated rats. In addition, ML 750mg/kg/day significantly (p?0.01) reduced oxidative stress and normalizes the activities of SOD, CAT, GPx and GRh compared to Triton-treated rats. Conclusion: The current study provides strong evidence that intragastric administration of ML 750mg/kg/day has a beneficial effect in treating dyslipidemia with decrease in oxidative stress.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"74 1","pages":"270-274"},"PeriodicalIF":0.0,"publicationDate":"2017-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80001221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparative Evaluation between Tympanoplasty with or Without Cortical Mastoidectomy 鼓室成形术加与不加皮质乳突切除术的比较评价

International Journal of Biomedical and Advance Research Pub Date : 2017-07-28 DOI: 10.7439/IJBAR.V8I7.4317

Harshali Girde, S. Gawarle, P. Keche

{"title":"A Comparative Evaluation between Tympanoplasty with or Without Cortical Mastoidectomy","authors":"Harshali Girde, S. Gawarle, P. Keche","doi":"10.7439/IJBAR.V8I7.4317","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4317","url":null,"abstract":"Aims and Objectives: To compare the results of tympanoplasty alone and tympanoplasty with cortical mastoidectomy in chronic suppurative otitis media (CSOM) patients in terms of graft uptake, perforation closureand improvement in hearing. Method: The study enrolling total 60 patients of either sex, age between 15 to > 45 years and were divided in two equal groups. Group A operated by type 1 tympanoplasty alone and group B operated by type 1 tympanoplasty with cortical mastoidectomy.The graft uptake rate and hearing improvement was compared between these two groups based on follow up and repeat audiogram on 12 th postoperative week. Results: In the presentstudy, majority of patients were in the age group of 26-35 years with female predominant by male to female ratio of 1: 3.6.Graft uptake success rate were more in group B (93.3 %)than in group A(90 %).Three months after the surgery, 22 (73.33%) patients showed hearing improvement in group A and 25 (83.3%) patients in group B which was not statistically significant. Conclusion: The graft uptake and hearing improvement were clinically better in group B but difference in two groups was statistically insignificant. Combining cortical mastoidectomy with tympanoplasty does not give additional benefit in terms of hearing improvement or graft uptake but ABC closure after 3 months of surgery was significantly better in group B.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"79 1","pages":"275-278"},"PeriodicalIF":0.0,"publicationDate":"2017-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75841822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

Palonosetron A Promising New Prophylactic for PONV 帕洛诺司琼:一种有前景的新型PONV预防药物

International Journal of Biomedical and Advance Research Pub Date : 2017-07-28 DOI: 10.7439/IJBAR.V8I7.4321

A. Patel, M. Sangawar, V. Shelgaonkar

{"title":"Palonosetron A Promising New Prophylactic for PONV","authors":"A. Patel, M. Sangawar, V. Shelgaonkar","doi":"10.7439/IJBAR.V8I7.4321","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I7.4321","url":null,"abstract":"Aim and Objective- The aim of the study was to evaluate the efficacy of palonosetron 0.075 mg for prevention of postoperative nausea and vomiting (PONV) in patients undergoing middle ear surgeries in comparison with ondansetron. Methods - In this prospective observational study, 70 healthy patients who were undergoing elective middle ear surgeries were divided into 2 groups: Group P (palonosetron 0.075 mg i.v., n = 35) and group C (ondansetron 8 mg i.v., n = 35). The drugs were given 5 minutes before induction of anaesthesia. The incidence of nausea, vomiting, retching, severity of nausea, use of recue antiemetic and incidence of complete response were evaluated. Results - The incidence of nausea, vomiting and severity of nausea was lower in palonosetron group as compared to ondansetron group but this difference was not statistically different. The incidence of use of rescue antiemetic (5.71% vs 23.53%) was significantly lower in palonosetron group. The incidence of complete response was higher in palonosetron group (88.87% vs 68.57%) but the difference was not statistically significant. Conclusion- The prophylactic intravenous administration of single dose of palonosetron 0.075 mg is not more effective in controlling postoperative nausea and vomiting as compared to ondansetron 8 mg in middle ear surgery.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"51 1","pages":"284-287"},"PeriodicalIF":0.0,"publicationDate":"2017-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81437891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nephroprotective Activity of Bark of Artocarpus Heterophyllus Lam 槐皮的肾保护作用

International Journal of Biomedical and Advance Research Pub Date : 2017-07-02 DOI: 10.7439/IJBAR.V8I6.3907

C. Bhattacharjee, A. Dutta

引用次数: 2

Hemostasis in Pregnancy Induced Hypertension (PIH) 妊娠高血压(PIH)的止血

International Journal of Biomedical and Advance Research Pub Date : 2017-06-29 DOI: 10.7439/IJBAR.V8I6.4203

P. Sathya, M. Kumar

{"title":"Hemostasis in Pregnancy Induced Hypertension (PIH)","authors":"P. Sathya, M. Kumar","doi":"10.7439/IJBAR.V8I6.4203","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I6.4203","url":null,"abstract":"Background: Pregnancy is a hypercoagulable state as the parturient is physiologically prepared against haemorrhage. Plasma fibrinogen level increases and platelet count decreases. Pregnancy induced Hypertension (PIH) is a syndrome complex of hypertension, oedema and proteinuria. In PIH, the physiological changes that occur in normal pregnancy are further aggravated and the woman is prone to develop Disseminated Intravascular Coagulation (DIC) which is a chief pathogenic factor in PIH. Objective: 1.To estimate platelet count and serum fibrinogen in normal pregnant women and women with PIH.2.To do bleeding time and clotting time in normal pregnant women & women with PIH& compare both. Material & methods: Two groups of pregnant women were involved. The first group (control) comprises normal pregnant women. The study group consists of pregnant women with PIH. Platelet count was done by direct method. Serum Fibrinogen was estimated by Rapid Turbidimetric method. Bleeding time was measured by Duke Method & Clotting time was measured by Wrights capillary tube method. Statistical analysis was done using appropriate student t test & SD. Results: In PIH group, platelet count is moderately reduced (Mean 1.72, P=< 0.05) and bleeding time is prolonged (mean 117.45, P0.001), Serum fibrinogen level is reduced (mean 237.14, P 0.001) and clotting time is prolonged(mean 16.9,P 0.001). Conclusion: Pregnant women with PIH are more prone to develop coagulation abnormalities which may result in bleeding tendency. Hence, serial estimations of platelet count & bleeding time can be used to assess primary hemostatic function. Plasma fibrinogen level &clotting time measurement may be used to assess secondary hemostatic function.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"51 6","pages":"250-254"},"PeriodicalIF":0.0,"publicationDate":"2017-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91511865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biochemical abnormalities and Vitamin D levels in sputum positive pulmonary tuberculosis 痰阳性肺结核的生化异常和维生素D水平

International Journal of Biomedical and Advance Research Pub Date : 2017-06-29 DOI: 10.7439/IJBAR.V8I6.4254

Phibakordor L. Nonglait, M. Lyngdoh, Preeti Jane Picardo, B. Barman, Akash Roy

{"title":"Biochemical abnormalities and Vitamin D levels in sputum positive pulmonary tuberculosis","authors":"Phibakordor L. Nonglait, M. Lyngdoh, Preeti Jane Picardo, B. Barman, Akash Roy","doi":"10.7439/IJBAR.V8I6.4254","DOIUrl":"https://doi.org/10.7439/IJBAR.V8I6.4254","url":null,"abstract":"Background: Tuberculosis has been associated with various biochemical abnormalities including low hyponatremia, serum albumin, hypocalcaemia, low vitamin D levels. Methods: 50 patients aged ? 18years of age with of sputum positive pulmonary tuberculosis were included in the study. Renal function, liver function, electrolytes and Vitamin D levels were measured at 0, 2 and 6 months of anti-tuberculosis treatment. The qualitative variables were analysed by chi-square tests. The quantitative variables were analysed by using paired t test. Five percent probability level was considered as statistically significant i.e., p<0.05. Results: The mean age was 38.5 years with a male to female ratio of 1.08:1. Hyponatremia was present in 24% of the patients. The mean total serum protein value were 6.720.89,7.420.74 and 8.150.68 g/dl and serum albumin of 2.970.50, 3.370.39 and 3.750.37 g/dl respectively at 0, 2 and 6 months. The mean serum calcium values observed were 8.20.63, 8.820.68 and 9.450.63 mg/dl at 0, 2 and 6 months respectively. The mean values for vitamin D at 0, 2 and 6 months were 9.146.94, 15.336.42 and 23.176.86 ng/ml respectively. 92% of the patients had low serum levels of vitamin D and 66% of the patients had serum vitamin D levels less than 10 ng/ml at presentation. Conclusion: Various biochemical abnormalities including hyponatraemia, low serum albumin and protein levels and low serum calcium levels are seen in pulmonary tuberculosis. Vitamin D levels are significantly lower in patients with TB and there is a significant improvement in the vitamin D levels with treatment of TB.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"150 1","pages":"255-258"},"PeriodicalIF":0.0,"publicationDate":"2017-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77381448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0