S. Hasija, Pawan K Singh, Anam Khan, Puja, S. Kalhan, S. Garg
{"title":"Hibernoma: A rare entity at Rare location: Case report of 2 cases with review of literature","authors":"S. Hasija, Pawan K Singh, Anam Khan, Puja, S. Kalhan, S. Garg","doi":"10.7439/IJBAR.V9I3.4665","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I3.4665","url":null,"abstract":"Hibernoma are rare benign tumors of brown adipose tissue. The tumor was first described in 1906 by Merkel who named them Pseudolipoma. The term Hibernoma was given by Grey in 1914 because of its similarity to brown fat in hibernating animal. Males are more often involved than females. Here we report on two patients of age group 14 years and 60 years male respectively. The tumor presented with swelling temporal region in first patient and with parietal region swelling in other patient.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"25 1","pages":"125-127"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86705352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Yadav, Lata Rajoria, J. Vyas, S. Hemani, Aditi Bansal
{"title":"An observational study of the demographic features and the risk factors of cervical and endometrial cancer","authors":"S. Yadav, Lata Rajoria, J. Vyas, S. Hemani, Aditi Bansal","doi":"10.7439/IJBAR.V9I3.4701","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I3.4701","url":null,"abstract":"Gynecological cancer is any cancer that starts in women reproductive organs. Over 75% of such women report in India for diagnosis and treatment at advance stage leading to high mortality rate. Cervical cancer is a preventable disease, and regular Pap smears have long been used in developed countries to screen for cervical cancers, accounting for their low-incidence rates. Unfortunately, in developing nations such as India, due to lack of awareness programs and no formal screening programs, most women have presented in the advanced stages of cervical cancer. The aim of the study was to find out the demographic features and factors which may be playing role in pathogenesis of cervical and endometrial cancers and prevention, early diagnosis and screening and thus timely intervention of these cancers. It is a observational study carried out on 100 indoor cancer patients admitted in Zenana Hospital, Jaipur in a 24 months period from May 2016 to November 2017. Result :Ca cervix was most prevalent in Hindu women of low socio-economic status in rural areas. While Endo-metrial cancer comparatively occurred in urban population. The patients were mostly from the outskirts of jaipur and nearby areas and lesser proportion belonged to the urban population. This study revealed an increasing incidence of carcinoma of the cervix with increasing parity. Conclusion: From this study it is evident that both cancer cervix and cancer endometrium have plenty of high risk conditions, environmental influences and unhealthy lifestyle habits associated with them. Thus identifying these high-risk factors, mass education on cancer awareness amongst the people and information regarding screening tests available can be done .","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"23 1","pages":"109-111"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78675255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Burden of Malaria in Rural area Jhansi- A clinico-epidemiological study.","authors":"V. Arya, K. Gunjan, N. Tiwari","doi":"10.7439/IJBAR.V9I3.4648","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I3.4648","url":null,"abstract":"Introduction: Malaria is a protozoan disease transmitted by the bite of infected Anopheles mosquitoes.WHO estimates that there were 216 million cases of malaria in 2016 resulting in 445,000 deaths. According to world malaria report 2012, India alone has an estimated 24 million cases per year. It is preventable and curable. Aims and objectives: To assess the burden of malaria in a rural area, and evaluate the clinico-epidemiological factors among malaria positive cases. Material and Methods: The study was conducted among 300 adult patients of malaria (Pf, Pv, Pf+ Pv) in the rural field practice area, by the Department of Community Medicine at MLB Medical College from March 2017 to October 2017. All the patients presenting fever with the suspicion of malaria were examined. Only peripheral smear / quantitative buffy coat positive patient was included. Results: Out of total 300 patients of malaria 147 (49%) patients were of P. falciparum , 110 (36.67%) were of P. vivax and 43(14.33%) were of mixed infection. There was no predilection observed in this study towards any sex. Fever was the most common manifestation followed by Chills and rigors. While altered sensorium was seen in 71 (23.67%). Conclusion: Use of multipronged strategies to combat the disease transmission and control with an integration of multi-sectoral collaboration is needed in a rural area.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"36 1","pages":"76-79"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80520511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Khandelwal, Deepti Agarwal, A. Agarwal, K. Arora
{"title":"Usefulness of Bronchial washings in diagnosing lung malignancy.","authors":"R. Khandelwal, Deepti Agarwal, A. Agarwal, K. Arora","doi":"10.7439/ijbar.v9i3.4666","DOIUrl":"https://doi.org/10.7439/ijbar.v9i3.4666","url":null,"abstract":"Objective: The present study was done to evaluate the yield of bronchial wash in cases of lung cancer. Methods: This is a 3 year retrospective study which included 163 cases of lung cancer in whom bronchial wash cytology had been done. Results: The age range was from 34 to 88 years and Male: Female ratio was 5.5:1. The sensitivity of bronchial wash was found to be 24.5% and the false negative index was 32.5%. The sensitivity of endobronchial biopsy was 93.4%. Tumor typing into small cell carcinoma and non-small cell carcinoma could be done on cytology in 85% of cases positive on bronchial wash. Squamous cell carcinoma was the most common type. Interestingly one case was diagnosed as Adenoid cystic carcinoma which was later confirmed on biopsy. Conclusion: There is still disagreement as to the value and reliability of bronchial wash cytology in diagnosing lung cancer. Bonchial wash cytology has low sensitivity for detecting lung cancer; however, it may be a useful diagnostic test in patients in whom endobronchial biopsy cannot be done.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"55 1","pages":"80-84"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87047581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The relationship between endometrial thickness and pregnancy rates in subfertil women underwent intrauterine insemination Following ovulation induction","authors":"S. Said, Muhiy Cheid Kadum Alkielabi","doi":"10.7439/IJBAR.V9I2.4545","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I2.4545","url":null,"abstract":"Objective: The aim of this study is the comparison of effects of Clomiphene Citrate (CC) & human menopausal Gonadotrophin (hMG) stimulated cycles on the Endometrial Thickness (ET) in intrauterine insemination (IUI) in one cycle & to establish any relation between ET on the day of IUI and achieving clinical pregnancy in these stimulated cycle.Study design: A prospective observational study was undertaken for assessing effects of clomiphene citrate (CC) and human menopausal gonadotrophin hMG stimulated cycle on the ET and clinical pregnancy in single IUI cycle.Subfertility cases were studied in two groups; Group A [ovulation induction (OI) with CC and IUI, n = 150] and Group B (OI with hMG and IUI, n = 150).Results: Comparable data obtained in mean, age, duration of subfertility female, male (only oligo sperm a) in both group range of ET of clinical pregnancy in group A (n = 21) were 8.0 – 12.9 mm and 9.0 – 12.9 mm in group B (n = 40). (p value < 0.001) ongoing pregnancy beyond 1st trimester was higher in group B (n= 42) than group A (n = 19).Conclusion: Mean ET and clinical pregnancy rate both were higher in hMG group compared to CC.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"32 1","pages":"50-54"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89378316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kavindra Borgaonkar, R. Patil, Swati Sawant Talekar
{"title":"Role of Cerebrospinal fluid Lactate Dehydrogenase in meningitis","authors":"Kavindra Borgaonkar, R. Patil, Swati Sawant Talekar","doi":"10.7439/IJBAR.V9I2.4671","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I2.4671","url":null,"abstract":"Background: Meningitis still remains a condition of significant mortality and morbidity in pediatric practice. Tubercular and bacterial meningitis form an important group of neurological diseases associated with considerable mortality and morbidity in children.Material and Methods: The present study was carried out in the Department of Biochemistry at Government Medical College and Hospital, Aurangabad during the period June 1999 to June 2001 on 40 patients of meningitis and 20 controls from pediatric age group. CSF and blood samples from patients suffering from pyogenic meningitis (32) (Group II), tuberculous meningitis (Group III) (8) and control subjects (Group I) (20) were examined. Statistical analysis was done by One way ANOVA non-parametric test with tukey-test to compare all the group was used and calculated by SPSS 19 version of the software.Result: In our study we have seen that CSF sugar was Significantly lower in the Pyogenic Meningitis Group (II) as compared to Controls (I) and Tuberculous meningitis (III) group (p 0.05). CSF Proteins were significantly higher in Pyogenic (II) and Tuberculous Meningitis group (III) as compared to controls (p 0.05). In present study: Mean CSF LDH value of meningitis (total) was significantly increased (P<0.05) as compared to controls. Mean CSF LDH value in meningitis (total) was 87.42±28 IU/L as compared to 26.85±10.79 IU/L in controls.Conclusion: We have concluded that LDH help the clinician for diagnosing meningitis in addition to the routine investigations, further LDH may help in the differentiation between pyogenic and tuberculous meningitis.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"38 1","pages":"64-69"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90375653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of plasma Leukotriene B4 levels in patients with alcoholic and nonalcoholic fatty liver disease","authors":"Haresingh Makwane, M. Varma, R. Jha","doi":"10.7439/ijbar.v9i2.4639","DOIUrl":"https://doi.org/10.7439/ijbar.v9i2.4639","url":null,"abstract":"Background: In worldwide, alcoholic and nonalcoholic fatty liver disease is a most common global health problem. Liver disease is characterized by inflammation and fibrosis. Leukotrienes B4 are implicated in an inflammation of liver cells. The aim of this study was estimation of LTB4 in pateint with alcoholic and non alcoholic fatty liver disease. Materials and Methods: In the present research study, we recruited total (n = 435) subjects and divided in alcoholic fatty liver disease (n = 149); nonalcoholic fatty liver disease (n = 137), and healthy control subjects (n = 150). Plasma LTB4 was measurement of ELISA method. Results: The present study shown that significantly increased levels of plasma LTB4 (p<0.001) in AFLD patients as compared with healthy controls, and also significantly increased (p <0.001) in NFALD patients when they compared with healthy controls. Conclusion: The identification of mechanism underlying the function of receptor that mediates responses of LTB4, and development of novel therapeutic agents for liver disease.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"4 1","pages":"55-58"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89989731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinicopathological Correlation of Portal Hypertension in Children and Management Strategies","authors":"Asmita Mahajan, R. Ghildiyal, Prachi S. Karnik","doi":"10.7439/IJBAR.V9I2.4667","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I2.4667","url":null,"abstract":"We studied 51 children with clinical setting of portal hypertension over a period of one and half years. Out of these, 27 (52.94%) were males and 24 (47.05%) were females. All the cases were subjected to biochemical, diagnostic, radiological investigations and liver biopsy. Portal hypertension was diagnosed by demonstrating on USG abdomen/ Doppler, the presence of collaterals of portal vein and esophageal varices on endoscopy. Treatment was initiated depending upon clinical presentation. The most common presenting complaints were hematemesis and malena (35.3%) followed by their combination with abdominal distension (19.6%). 86.3% patients had anemia mostly due to upper GI bleed. 35.3% patients had leucopenia while 47.1% had thrombocytopenia. Only 18 (i.e. 35.3%) had Hypersplenism. Maximum patients who bled more than twice had a mild (41.2%) or severe (29.4%) derangement of prothrombin time. The etiology of portal hypertension turned out to be extra- hepatic portal vein obstruction in 86.3% cases. There were 2 cases each (3.9% each) of Wilson’s disease and Budd-Chiari syndrome. One (2%) was secondary to chronic liver disease due to hepatitis C infection, one was extra- hepatic biliary atresia and one was autoimmune hepatitis. 9.8% cases required drugs in the form of somatostatin drip and all these required a packed cell transfusion as well. 23 patients (45.1%) required only blood transfusion without a somatostatin infusion. Those with severe acute bleeding usually were given somatostatin infusion. The variceal size at presentation was a very important predictor of the morbidity and outcome.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"38 1","pages":"70-75"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82427633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Hasija, S. Garg, Pawan K Singh, S. Kalhan, Neerav Saini, Anam Khan
{"title":"Cytomorphological spectrum of Extra Pulmonary Tuberculosis in Rural Tertiary Care Hospital: A Study","authors":"S. Hasija, S. Garg, Pawan K Singh, S. Kalhan, Neerav Saini, Anam Khan","doi":"10.7439/IJBAR.V9I2.4617","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I2.4617","url":null,"abstract":"This is estimated that about 1/3 rd of world population is infected with mycobacterium tuberculosis & most of the cases in Asia (55%) and Africa (31%) rest in others. Extra Pulmonary Tuberculosis (EPTB) reversed the epidemiological trend over the last several years. EPTB was has been increasing in absolute numbers and in proportions of all reported TB cases. Since very less data is available on EPTB and its distribution especially from this part of India therefore this study has been planned to assess the pattern of EPTB & the role of Fine Needle Aspiration Cytology (FNAC) in diagnosing these cases. This is a retrospective analysis of patients with peripheral lymphadenopathy & swelling on various sites. All the patients had fine needle aspiration. Smears were made, fixed in 95% alcohol and stained with giemsa, hematoxylin and eosin and Zeihl Neelsen (ZN) stains. The study includes 271 cases of extrapulmonary tuberculosis in which patient age range from one year to more than 51 years. Maximum no. of cases falls in the age group between 11 to 20 years. The mean age was 22.6 years. Females (63%) had higher proportion of EPTB than males (37%). Aspirates were mainly from cervical lymph nodes. Other sites were chest wall, breast, thigh, back etc. Macroscopically, 106 (39%) of the aspirates were purulent and 165 (61%) had necrotic material. Microscopy we divide it in three patterns, Pattern A (Epithelioid granuloma without necrosis) (39.11%); Pattern B (Epithelioid granuloma with necrosis) (45.75%); Pattern C (necrosis/neutrophilic aspirate) (15.12%). Staining for acid-fast bacilli was positive in 47 (17.34%) cases. Early diagnosis of extrapulmonary tuberculosis in a resource-limited setting can be achieved with fine needle aspiration cytology technique (FNAC). This will ensure prompt treatment and thus reduce attendant morbidity and mortality.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"124 1","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"2018-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77475184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of total laparoscopic Hysterectomy versus vaginal hysterectomy for benign non prolapsed uterus","authors":"P. Mehendale, Aruna Menon, A. Kapur, S. Srinivas","doi":"10.7439/IJBAR.V9I1.4605","DOIUrl":"https://doi.org/10.7439/IJBAR.V9I1.4605","url":null,"abstract":"Background : Vaginal hysterectomy is a well established and time tested procedure which is being done since the last 150 years and thus has been refined to a great degree, but it has been less successful due to lack of experience and enthusiasm among Gynaecologists, due to a misconception that the abdominal route is safer and easier. Objective: The present study was undertaken to compare outcomes of conventional vaginal hysterectomy and total laparoscopic hysterectomy in women with benign non prolapsed uterus. Methods: Total 50 cases of non prolapsed uterus requiring hysterectomy were systematically allocated into two groups of 25 patients in each group, (Vaginal and total laparoscopic hysterectomy group). All patients underwent pelvic ultrasound (USG). Surgical techniques, operating time, estimated blood loss and/or episodes of accidental bleeding requiring intervention intra-or post-operatively were compared. Other factors such as post operative pain, post-operative complications, conversion to laparotomy, and length of hospital stay were also recorded for each case. Results: We found that blood loss in vaginal hysterectomy was more than in total laparoscopic hysterectomy. Post-operative pain and post complications were also more in the vaginal hysterectomy group. Operation time was however more in the total laparoscopic hysterectomy group but recovery time was less. Conclusion: In the present study, we found advantages of laparoscopic hysterectomy over vaginal hysterectomy in terms of lesser blood loss, postoperative pain and postoperative complications, a larger study with emphasis on long term effects may be essential to establish superiority of total laparoscopic hysterectomy over vaginal hysterectomy.","PeriodicalId":13848,"journal":{"name":"International Journal of Biomedical and Advance Research","volume":"134 1","pages":"45-49"},"PeriodicalIF":0.0,"publicationDate":"2018-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80300062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}