International Journal of Angiology最新文献_第8页

Pure Endovascular versus Hybrid Approach for Management of Iliofemoral Arterial Disease: A Randomized Controlled Trial. 单纯血管内与混合治疗髂股动脉疾病的方法：一项随机对照试验。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-23 eCollection Date: 2023-06-01 DOI: 10.1055/s-0042-1756622

Ahmed A Shaker, Ahmed H Shehata, Khaled M Alhindawy, Walid El Daly

{"title":"Pure Endovascular versus Hybrid Approach for Management of Iliofemoral Arterial Disease: A Randomized Controlled Trial.","authors":"Ahmed A Shaker, Ahmed H Shehata, Khaled M Alhindawy, Walid El Daly","doi":"10.1055/s-0042-1756622","DOIUrl":"10.1055/s-0042-1756622","url":null,"abstract":"Common femoral artery (CFA) atherosclerotic lesions currently remain one of the last limitations for adoption of endovascular repair as the first-line treatment, easy surgical accessibility, and, last but not least, favorable long-term outcomes, still making CFA disease treatment part of the surgical domain. In the last 5 years, improvement of the endovascular equipment and technical skills of the operators have led to an increase in percutaneous CFA procedures. A single-center randomized prospective study of 36 symptomatic (Rutherford 2-4) CFA stenotic or occlusive lesions were included, and patients were randomized over two groups based on the management approach SUPERA versus hybrid technique. Patients had a mean age 60.8 ± 8.2 years. Thirty-two (88.9%) patients reported improvement of the clinical symptoms, 28 (87.5%) patients had intact pulse postoperatively, and 28 (87.5%) had patent vessels. Follow-up showed that none developed reocclusion or restenosis during the period of follow-up. Comparison of difference in peak systolic velocity ratio (PSVR) among study groups showed that the hybrid technique had more reduction of PSVR postintervention compared to the SUPERA group with a p -value of < 0.0001. Safety and feasibility of endovascular approach with the SUPERA stent to the CFA (no stent zone) has low incidence of postoperative morbidity and mortality in well experienced surgical hands.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 2","pages":"88-94"},"PeriodicalIF":0.6,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191691/pdf/10-1055-s-0042-1756622.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9499847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Could Plasma CXCL12 Predict Ventricular Dysfunction in Patients with Severe Myocardial Infarction? 血浆CXCL12能预测严重心肌梗死患者的心室功能障碍吗？

IF 0.6

International Journal of Angiology Pub Date : 2022-09-23 eCollection Date: 2023-09-01 DOI: 10.1055/s-0042-1756488

Hussam A S Murad, Marwan A Bakarman

{"title":"Could Plasma CXCL12 Predict Ventricular Dysfunction in Patients with Severe Myocardial Infarction?","authors":"Hussam A S Murad, Marwan A Bakarman","doi":"10.1055/s-0042-1756488","DOIUrl":"10.1055/s-0042-1756488","url":null,"abstract":"Plasma level of chemokine CXCL12 can predict adverse cardiovascular outcomes in patients with coronary artery disease, but data on its relationship with severity of coronary stenosis in cases of severe myocardial infarction (MI) are scarce and conflicting. The objective of this study was to investigate link between plasma CXCL12 levels and different grades of left ventricular ejection fraction (LVEF) in statin-treated and -untreated patients with severe MI. A total of 198 consecutive patients with first-time severe MI (ST-elevated myocardial infarction [STEMI], n = 121 and non-ST-elevated myocardial infarction [NSTEMI], n = 77) were recruited from Coronary Care Unit, King Abdulaziz University Hospital. They have one to two coronary arteries blocked ≥50%, or three arteries blocked 30 to 49%. Demographic and clinical criteria were collected and plasma CXCL12 level was measured. No correlations were detected between demographic and clinical criteria and CXCL12 level. While troponin peaks and LVEF significantly differed between STEMI and NSTEMI patients, CXCL12 level showed nonsignificant changes. Plasma CXCL12 levels decreased significantly in statin-treated patients compared with those untreated. From receiver operating characteristic (ROC) analysis, high CXCL12 levels were associated with no statin therapy. For STEMI and NSTEMI patients, area under the receiver operating characteristic curve for CXCL12 test were 0.685 and 0.820, while sensitivity and specificity values were 75.9 and 54.8%, and 73.1 and 84%, respectively. Plasma CXCL12 levels showed nonsignificant changes with different ranges of LVEF and troponin peaks. In patients with severe MI, irrespective of statin therapy, plasma CXCL12 showed no correlation with different ranges of LVEF suggesting that it cannot predict left ventricular dysfunction in these cases. However, cross-sectional design of this study is a limitation.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"32 3","pages":"165-171"},"PeriodicalIF":0.6,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10421681/pdf/10-1055-s-0042-1756488.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10371911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mechanical Function of the Atrial Diastole: A New Discovery 心房舒张功能的新发现

IF 0.6

International Journal of Angiology Pub Date : 2022-09-12 DOI: 10.1055/s-0042-1753493

S. Raju

引用次数: 0

Involvement of AGE and Its Receptors in the Pathogenesis of Hypertension in Elderly People and Its Treatment. AGE 及其受体在老年人高血压发病机制中的参与及其治疗。

IF 0.5

International Journal of Angiology Pub Date : 2022-09-08 eCollection Date: 2022-12-01 DOI: 10.1055/s-0042-1756175

Kailash Prasad

{"title":"Involvement of AGE and Its Receptors in the Pathogenesis of Hypertension in Elderly People and Its Treatment.","authors":"Kailash Prasad","doi":"10.1055/s-0042-1756175","DOIUrl":"10.1055/s-0042-1756175","url":null,"abstract":"Both systolic and diastolic blood pressures increase with age up to 50 to 60 years of age. After 60 years of age systolic pressure rises to 84 years of age but diastolic pressure remains stable or even decreases. In the oldest age group (85-99 years), the systolic blood pressure (SBP) is high and diastolic pressure (DBP) is the lowest. Seventy percent of people older than 65 years are hypertensive. This paper deals with the role of advanced glycation end products (AGE) and its cell receptor (RAGE) and soluble receptor (sRAGE) in the development of hypertension in the elderly population. Plasma/serum levels of AGE are higher in older people as compared with younger people. Serum levels of AGE are positively correlated with age, arterial stiffness, and hypertension. Low serum levels of sRAGE are associated with arterial stiffness and hypertension. Levels of sRAGE are negatively correlated with age and blood pressure. Levels of sRAGE are lower in patients with arterial stiffness and hypertension than patients with high levels of sRAGE. AGE could induce hypertension through numerous mechanisms including, cross-linking with collagen, reduction of nitric oxide, increased expression of endothelin-1, and transforming growth factor-β (TGF-β). Interaction of AGE with RAGE could produce hypertension through the generation of reactive oxygen species, increased sympathetic activity, activation of nuclear factor-kB, and increased expression of cytokines, cell adhesion molecules, and TGF- β. In conclusion, the AGE-RAGE axis could be involved in hypertension in elderly people. Treatment for hypertension in elderly people should be targeted at reduction of AGE levels in the body, prevention of AGE formation, degradation of AGE in vivo, downregulation of RAGE expression, blockade of AGE-RAGE interaction, upregulation of sRAGE expression, and use of antioxidants.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"31 4","pages":"213-221"},"PeriodicalIF":0.5,"publicationDate":"2022-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803554/pdf/10-1055-s-0042-1756175.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10536694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Classification and Stratification of Pulmonary Embolisms. 肺栓塞的分类和分层。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1756218

Cody Russell, Suresh Keshavamurthy, Sibu Saha

引用次数: 0

Diagnosis, Diagnostic Tools, and Risk Stratification for Contemporary Treatment of Pulmonary Embolism. 当代肺栓塞治疗的诊断、诊断工具和风险分层。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1756177

Taylor C Remillard, Arber Kodra, Michael Kim

{"title":"Diagnosis, Diagnostic Tools, and Risk Stratification for Contemporary Treatment of Pulmonary Embolism.","authors":"Taylor C Remillard, Arber Kodra, Michael Kim","doi":"10.1055/s-0042-1756177","DOIUrl":"https://doi.org/10.1055/s-0042-1756177","url":null,"abstract":"Pulmonary embolism (PE) is quite common and is associated with significant morbidity and mortality. It is estimated that it is the cause of approximately 100,000 annual deaths in the United States. With great variability in presenting symptoms of PE, poor recognition of PE can be fatal. As such, many risk scores have been created to identify the sickest patients. Choosing the appropriate imaging modality is also critical. Invasive pulmonary angiography was once the gold standard to establish the diagnosis. With the advent of nuclear imaging, V/Q scans, invasive angiography has been phased out for diagnosing acute PE. At present, the standard for diagnosis of acute PE is computed tomography pulmonary angiography. In select patient cohorts, nuclear studies remain the modality of choice. Once the diagnosis of acute PE is established, there is a broad spectrum of severity in outcome which has led to substantial focus and development of risk stratification prediction models. We will discuss making the proper diagnosis with contemporary diagnostic tools and risk stratifying patients with PE to receive the correct treatment.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"31 3","pages":"150-154"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507591/pdf/10-1055-s-0042-1756177.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10053083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Massive Embolism: Knife versus PCI. 大量栓塞:刀与PCI。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1755573

Scarlett Tohme, Joshua S Newman, Christopher Gasparis, Frank Manetta

引用次数: 0

The Pulmonary Embolism Response Team: Rationale, Operation, and Outcomes. 肺栓塞反应小组:基本原理、手术和结果。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1750328

James J Glazier, Skarlet Patiño-Velasquez, Carlos Oviedo

{"title":"The Pulmonary Embolism Response Team: Rationale, Operation, and Outcomes.","authors":"James J Glazier, Skarlet Patiño-Velasquez, Carlos Oviedo","doi":"10.1055/s-0042-1750328","DOIUrl":"https://doi.org/10.1055/s-0042-1750328","url":null,"abstract":"The pulmonary embolism response team (PERT) is an institutionally based multidisciplinary team that is able to rapidly assess and provide treatment for patients with acute pulmonary embolism (PE). Intrinsic to the team's structure is a formal mechanism to execute a full range of medical, endovascular, and surgical therapies. In addition, the PERT provides appropriate multidisciplinary follow-up of patients. In the 10 years since the PERT was first introduced, it has gained acceptance in many centers in the United States and around the world. These PERTs have joined together to form an international association, called the PERT Consortium. The mission of this consortium is to advance the diagnosis, treatment, and outcomes of patients with PE. There is considerable evidence that the PERT model improves delivery and standardization of care of PE patients, particularly those patients with massive and submassive PE. However, it is not yet clear whether PERTs improve clinical outcomes. A large prospective database is currently being compiled by the PERT Consortium. Analysis of this database will likely further delineate the role of PERTs in the management of intermediate-to-high risk PE patients and, importantly, help determine in which PE patients PERT may improve clinical outcomes.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"31 3","pages":"198-202"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507552/pdf/10-1055-s-0042-1750328.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10445615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Percutaneous Management of Pulmonary Embolism. 经皮肺栓塞治疗的进展。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1756174

Jimmy Kerrigan, Michael Morse, Elias Haddad, Elisabeth Willers, Chand Ramaiah

{"title":"Advances in Percutaneous Management of Pulmonary Embolism.","authors":"Jimmy Kerrigan, Michael Morse, Elias Haddad, Elisabeth Willers, Chand Ramaiah","doi":"10.1055/s-0042-1756174","DOIUrl":"https://doi.org/10.1055/s-0042-1756174","url":null,"abstract":"Acute pulmonary embolism (PE) is a leading cause of morbidity and mortality worldwide. Systemic anticoagulation remains the recommended treatment for low-risk PE. Systemic thrombolysis is the recommended treatment for PE with hemodynamic compromise (massive/high-risk PE). A significant number of patients are not candidates for systemic thrombolysis due to the bleeding risk associated with thrombolytics. Historically, surgical pulmonary embolectomy (SPE) was recommended for massive PE with hemodynamic compromise for these patients. In the last decade, catheter-directed thrombolysis (CDT) has largely replaced SPE in the patient population with intermediate risk PE (submassive), defined as right heart strain (as evidenced by right ventricle enlargement on echocardiogram and/or computed tomography, usually along with elevation of troponin or B-type natriuretic peptide). Use of CDT increased in the last few years due to high incidence of PE in hospitalized patients with coronavirus disease 2019 pneumonia, and the use of mechanical thrombectomy (initially reserved for those with contraindications to thrombolysis) has also grown. In this article, we discuss the value of the PE response team, our approach to management of submassive (intermediate risk) and massive (high risk) PE with systemic thrombolytics, CDT, mechanical thrombectomy, and surgical embolectomy.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"31 3","pages":"203-212"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507563/pdf/10-1055-s-0042-1756174.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10492935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Contemporary Treatment of Pulmonary Embolism: Medical Treatment and Management. 当代肺栓塞的治疗:医学治疗与管理。

IF 0.6

International Journal of Angiology Pub Date : 2022-09-01 DOI: 10.1055/s-0042-1750329

Stephen Moreland, Debabrata Mukherjee, Nils P Nickel

{"title":"Contemporary Treatment of Pulmonary Embolism: Medical Treatment and Management.","authors":"Stephen Moreland, Debabrata Mukherjee, Nils P Nickel","doi":"10.1055/s-0042-1750329","DOIUrl":"https://doi.org/10.1055/s-0042-1750329","url":null,"abstract":"Pulmonary embolus (PE) is defined as obstruction of the pulmonary artery or one of its branches by material (e.g., thrombus, tumor, air, or fat) but most commonly due to thrombus originating from the lower extremity deep veins. We reviewed the current literature describing the optimal medical treatment and management of PE. Databases (PubMed, the Cochrane Library, Embase, EBSCO, Web of Science, and CINAHL) were searched for relevant studies and guidelines for management of patients with PE. The initial approach to patients with suspected PE should focus upon stabilizing the patient while further workup for risk stratification is in progress. In most cases, anticoagulation should ideally be started even prior to confirming PE, if risk-benefit regarding suspicion of PE and bleeding risk is favorable. Once the diagnosis is confirmed, risk stratification will guide further therapies consisting of anticoagulation, thrombolysis, or catheter-directed interventions. Data for initial, long-term, and indefinite anticoagulation, and factors that determine whether or not a patient can be treated in the outpatient setting, are reviewed and discussed.","PeriodicalId":13798,"journal":{"name":"International Journal of Angiology","volume":"31 3","pages":"155-161"},"PeriodicalIF":0.6,"publicationDate":"2022-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9507607/pdf/10-1055-s-0042-1750329.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9832970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0