Contemporary Treatment of Pulmonary Embolism: Medical Treatment and Management.

IF 0.5 Q4 PERIPHERAL VASCULAR DISEASE
Stephen Moreland, Debabrata Mukherjee, Nils P Nickel
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引用次数: 0

Abstract

Pulmonary embolus (PE) is defined as obstruction of the pulmonary artery or one of its branches by material (e.g., thrombus, tumor, air, or fat) but most commonly due to thrombus originating from the lower extremity deep veins. We reviewed the current literature describing the optimal medical treatment and management of PE. Databases (PubMed, the Cochrane Library, Embase, EBSCO, Web of Science, and CINAHL) were searched for relevant studies and guidelines for management of patients with PE. The initial approach to patients with suspected PE should focus upon stabilizing the patient while further workup for risk stratification is in progress. In most cases, anticoagulation should ideally be started even prior to confirming PE, if risk-benefit regarding suspicion of PE and bleeding risk is favorable. Once the diagnosis is confirmed, risk stratification will guide further therapies consisting of anticoagulation, thrombolysis, or catheter-directed interventions. Data for initial, long-term, and indefinite anticoagulation, and factors that determine whether or not a patient can be treated in the outpatient setting, are reviewed and discussed.

当代肺栓塞的治疗:医学治疗与管理。
肺栓塞(Pulmonary embolus, PE)被定义为由物质(如血栓、肿瘤、空气或脂肪)阻塞肺动脉或其分支,但最常见的原因是源于下肢深静脉的血栓。我们回顾了目前有关PE的最佳治疗和管理的文献。检索数据库(PubMed、Cochrane Library、Embase、EBSCO、Web of Science和CINAHL),查找PE患者管理的相关研究和指南。疑似PE患者的初始治疗方法应侧重于稳定患者,同时进行进一步的风险分层检查。在大多数情况下,如果怀疑PE和出血风险的风险-收益有利,理想情况下,抗凝治疗应在确诊PE之前开始。一旦确诊,风险分层将指导进一步的治疗,包括抗凝、溶栓或导管定向干预。初步,长期和无限期抗凝的数据,以及决定患者是否可以在门诊治疗的因素,进行了回顾和讨论。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
International Journal of Angiology
International Journal of Angiology PERIPHERAL VASCULAR DISEASE-
CiteScore
1.30
自引率
16.70%
发文量
57
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