International Journal of Clinical Pediatrics最新文献_第5页

Accidental Methadone Poisoning in a Four-Year-Old Child Reversed With Continuous Intravenous Infusion of Naloxone 连续静脉输注纳洛酮逆转4岁儿童意外美沙酮中毒

International Journal of Clinical Pediatrics Pub Date : 2021-03-19 DOI: 10.14740/IJCP386

Balamurugan Supparamaniam, Rahmah Yunus, J. Fong, K. Tang

{"title":"Accidental Methadone Poisoning in a Four-Year-Old Child Reversed With Continuous Intravenous Infusion of Naloxone","authors":"Balamurugan Supparamaniam, Rahmah Yunus, J. Fong, K. Tang","doi":"10.14740/IJCP386","DOIUrl":"https://doi.org/10.14740/IJCP386","url":null,"abstract":"Reported case of methadone poisoning among children is infrequent in Malaysia. Since the implementation of methadone maintenance therapy (MMT) programme by Malaysian Ministry of Health in year 2006, there are only three case reports of methadone poisoning in children. Methadone toxicity in children can be deadly if antidote and supportive measures are not instituted in time. We report a case of accidental ingestion of about 25 mg of methadone in a 4-year-old boy. The methadone syrup belonged to his father, a former intravenous drug user (IVDU), who is currently a participant of the MMT detoxification programme under the supervision of a licensed general practitioner. The child presented with typical early signs and symptoms opioid toxicity. Upon examination, vital signs were normal, but he appeared lethargic and drowsy. Venous blood gas results noted mild respiratory acidosis and complete blood count revealed leukocytosis. He was treated with continuous intravenous infusion (CIVI) naloxone 10 µg/kg/h for approximately 78 h. He was hospitalized for 6 days and discharged well. Advice should be given to family who has patient under MMT programme with take-home doses to be more cautious in storage of methadone syrup at home, and to keep the bottle far from the reach of children. Methadone poisoning in children can be deadly and early administration of naloxone as CIVI can effectively reverse its toxicity. Int J Clin Pediatr. 2021;10(1):18-23 doi: https://doi.org/10.14740/ijcp386","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"54 1","pages":"18-23"},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78904242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Kawasaki Disease Shock Syndrome: A Challenging Diagnosis 川崎病休克综合征:一个具有挑战性的诊断

International Journal of Clinical Pediatrics Pub Date : 2021-03-19 DOI: 10.14740/IJCP425

Raquel Penteado, A. Simões, A. Palma, Joana V Andrade, T. Dionísio

{"title":"Kawasaki Disease Shock Syndrome: A Challenging Diagnosis","authors":"Raquel Penteado, A. Simões, A. Palma, Joana V Andrade, T. Dionísio","doi":"10.14740/IJCP425","DOIUrl":"https://doi.org/10.14740/IJCP425","url":null,"abstract":"The authors present a clinical report of a previously healthy 4-year-old girl, admitted to a pediatric intensive care unit (PICU) presenting with a fluid-refractory shock. She was initially admitted in the pediatric emergency department with a history of fever and petechial rash and an initial diagnosis of invasive meningococcal disease was placed. During the PICU stay, acute myocarditis with episodes of supraventricular tachycardia and lateral and inferior wall myocardial ischemia, ileitis and serositis were noted. At 14th day of stay, she developed peeling on the hands and feet and, aneurysmatic ectasia of the coronary arteries were visualized in transthoracic echocardiography, allowing the diagnosis of Kawasaki disease shock syndrome (KDSS). The child improved after empirical treatment with antibiotics, intravenous immunoglobulin and corticosteroid therapy. She was started on antiplatelet therapy due to changes in the coronary arteries. Early recognition of KDSS can be challenging; however, a delayed diagnosis increases the risk of coronary changes and a fatal outcome. Int J Clin Pediatr. 2021;10(1):10-17 doi: https://doi.org/10.14740/ijcp425","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"26 1","pages":"10-17"},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81533019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transient Waterhouse-Friderichsen Syndrome in a Child: A Case Report 儿童短暂性Waterhouse-Friderichsen综合征1例报告

International Journal of Clinical Pediatrics Pub Date : 2021-03-19 DOI: 10.14740/IJCP429

G. Trobia, Federica Sullo, M. Finocchiaro, E. Gitto, C. Damiano, R. Caccamo, R. Ranno, Vita Antonella Di Stefano

引用次数: 1

Successfully Treating Hypercalcemia Secondary to Subcutaneous Fat Necrosis With Pamidronate: A Case Series 帕米膦酸钠成功治疗继发于皮下脂肪坏死的高钙血症:一个病例系列

International Journal of Clinical Pediatrics Pub Date : 2021-03-19 DOI: 10.14740/IJCP420

Ryan J Dyess, P. Gandham, Bradly J. Thrasher

引用次数: 0

Primary Care Referral Perspectives in Pediatric Failure to Thrive and Outcomes From a Diagnostic Clinic 初级保健转诊的观点在儿科失败茁壮成长和结果从诊断诊所

International Journal of Clinical Pediatrics Pub Date : 2021-02-05 DOI: 10.14740/IJCP419

G. Lisius, Tony R Tarchichi

{"title":"Primary Care Referral Perspectives in Pediatric Failure to Thrive and Outcomes From a Diagnostic Clinic","authors":"G. Lisius, Tony R Tarchichi","doi":"10.14740/IJCP419","DOIUrl":"https://doi.org/10.14740/IJCP419","url":null,"abstract":"Background: Decades of data demonstrate the overwhelming rates of failure to thrive (FTT) nutritional causes (80-90%) even in patients with complex medical conditions and diagnoses. Primary care providers (PCPs), the initial FTT evaluators, have been underrepresented in the FTT literature, despite their pivotal role in overseeing management. Our purpose was to assess PCPs’ FTT referral strategies and their concerns for their FTT patients referred to an academic pediatrician diagnostic clinic. Methods: We surveyed PCPs who referred FTT patients to a diagnostic clinic (the Diagnostic Referral Group (DRG)) for their main concern prompting referral, and next management if consult was unavailable. Chart review determined the hospitalization rates of FTT patients, and DRG interventions. Results: Of the 81 PCP responses, 66.7% were most concerned with an uncertain underlying diagnosis, contrasting with the 20.6% of patients that DRG providers suspected to have an organic etiology. PCPs’ next preferable management was subspecialist referral (58.0%) and hospitalization (22.2%). DRG providers most commonly recommended nutritional interventions such as increasing caloric density, decreased snacking and juice, and structured meals for 72.4% of patients. Conclusions: This study suggests that FTT due to nutritional causes continues to be a challenging diagnosis for PCPs. More investigation is needed to identify interventions to empower primary providers to diagnose nutritional causes, such as practical standardized assessments to evaluate the nutritional and psychosocial FTT contributors. Int J Clin Pediatr. 2021;000(000):000-000 doi: https://doi.org/10.14740/ijcp419","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"99 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2021-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84105912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Presumed Encephalitis With a Reversible Splenial Lesion 疑似脑炎伴可逆性脾损害

International Journal of Clinical Pediatrics Pub Date : 2021-01-01 DOI: 10.14740/IJCP405

N. Cabrera, E. C. Martinez, María M. Cabrera, Lelia Romero

{"title":"Presumed Encephalitis With a Reversible Splenial Lesion","authors":"N. Cabrera, E. C. Martinez, María M. Cabrera, Lelia Romero","doi":"10.14740/IJCP405","DOIUrl":"https://doi.org/10.14740/IJCP405","url":null,"abstract":"Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a clinicoradiologic syndrome which consists of a transient lesion usually located in the midline of the corpus callosum that shows restricted diffusion. The exact pathophysiology of this entity is still unknown. We present the case of a 9-year-old boy with a history of 3 days of headache and vomiting associated with an episode of syncope and mild hyponatremia. Magnetic resonance imaging (MRI) findings included a focal lesion with well-defined margins on the splenium of the corpus callosum with hyperintensity on T2 and diffusion-weighted images. The patient underwent full recovery, and a follow-up MRI 5 months later showed no signs of the initial lesion. In conclusion, MERS is part of the spectrum of cytotoxic lesions of the corpus callosum, which must be recognized as secondary to a several causes, to avoid an erroneous diagnosis and treatment of the patient. It should be emphasized the importance of continuing research on this type of process to clarify its pathophysiology as well as the long-term effects. Int J Clin Pediatr. 2021;10(1):24-27 doi: https://doi.org/10.14740/ijcp405","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"121 1","pages":"24-27"},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83088763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elevated Lipase Associated With COVID-19 Possibly due to Acute Pancreatitis in a Pediatric Patient: A Case Report 脂肪酶升高与COVID-19可能是由于儿科患者急性胰腺炎所致:1例报告

International Journal of Clinical Pediatrics Pub Date : 2020-11-04 DOI: 10.14740/ijcp401

Shruthi Shekar, Neelam Sarwar, M. Kalia, J. Castellanos, F. Pelliccia, J. Gill

{"title":"Elevated Lipase Associated With COVID-19 Possibly due to Acute Pancreatitis in a Pediatric Patient: A Case Report","authors":"Shruthi Shekar, Neelam Sarwar, M. Kalia, J. Castellanos, F. Pelliccia, J. Gill","doi":"10.14740/ijcp401","DOIUrl":"https://doi.org/10.14740/ijcp401","url":null,"abstract":"As the global pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) advances, the challenge of understanding its wide spectrum of symptoms and sequelae continues to be a priority in the medical world. There are not many case reports on the atypical presenting features of coronavirus disease 2019 (COVID-19), especially in the pediatric population. Discussed here is a case of acute pancreatitis in a 14-year-old male who presented with abdominal pain without any other typical COVID-19 symptoms. Workup was significant for positive SARS-CoV-2 polymerase chain reaction (PCR), elevated lipase, and computed tomography of the abdomen and pelvis with oral and intravenous contrast showed an indistinct margin of the pancreatic tail and left upper quadrant ascites, supportive of early pancreatitis. Clinical and laboratory improvement was noted after treatment with bowel rest, intravenous fluids, and antibiotics. This case highlights the concern that acute pancreatitis may be a complication associated with COVID-19. Identifying its signs may enable earlier diagnosis and treatment. Int J Clin Pediatr. 2020;9(4):125-129 doi: https://doi.org/10.14740/ijcp401","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"344 1","pages":"125-129"},"PeriodicalIF":0.0,"publicationDate":"2020-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77685005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Insights Into Management of Camurati-Engelmann Disease: A Case Series of Three Siblings Camurati-Engelmann病的治疗:三个兄弟姐妹的病例系列

International Journal of Clinical Pediatrics Pub Date : 2020-11-04 DOI: 10.14740/ijcp403

W. H. Slemp, J. Hunter, Elizabeth T. Walsh, Cathrine Constantacos, D. F. Crudo

{"title":"Insights Into Management of Camurati-Engelmann Disease: A Case Series of Three Siblings","authors":"W. H. Slemp, J. Hunter, Elizabeth T. Walsh, Cathrine Constantacos, D. F. Crudo","doi":"10.14740/ijcp403","DOIUrl":"https://doi.org/10.14740/ijcp403","url":null,"abstract":"Camurati-Engelmann disease (CED) is an autosomal dominant skeletal dysplasia characterized by progressive sclerosis of long bones due to a mutation in the transforming growth factor beta-1 gene. Patients experience progressive pain, weakness, and fatigability over time. There are no consensus guidelines for treatment though the use of several types of glucocorticoids, angiotensin II receptor blockers, and other therapies have been described. We present the cases of three siblings with CED managed with different treatment modalities over time (prednisone, losartan, and deflazacort). We provide objective data (pain scores, walk-test results, erythrocyte sedimentation rates) to demonstrate therapeutic efficacy. Prednisone resulted in the greatest improvement in pain; however, its use was limited by significant weight gain. Deflazacort was successful in improving pain and fatigability without the weight gain. Risks and benefits must be considered carefully as the cost of deflazacort is significantly higher than prednisone or losartan. Int J Clin Pediatr. 2020;9(4):130-134 doi: https://doi.org/10.14740/ijcp403","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"33 1","pages":"130-134"},"PeriodicalIF":0.0,"publicationDate":"2020-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86904575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Febrile Morbilliform Rash as a Clinical Presentation of COVID-19 in a Pediatric Patient 发热麻疹样皮疹作为COVID-19儿科患者的临床表现

International Journal of Clinical Pediatrics Pub Date : 2020-11-04 DOI: 10.14740/ijcp408

M. Almutairi, Amani Azizalrahman

{"title":"Febrile Morbilliform Rash as a Clinical Presentation of COVID-19 in a Pediatric Patient","authors":"M. Almutairi, Amani Azizalrahman","doi":"10.14740/ijcp408","DOIUrl":"https://doi.org/10.14740/ijcp408","url":null,"abstract":"The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in January 2020 resulted in a worldwide public health emergency. While the pediatric age group currently includes no more than 2% of the population diagnosed with coronavirus disease 2019 (COVID-19), the clinical manifestations in this cohort can range from upper respiratory tract symptoms to respiratory system and multiorgan failure. Interestingly, most of the pediatric COVID-19 patients are asymptomatic at the time of presentation. As such, the full clinical spectrum of this disease remains unknown. We describe here the case of a previously healthy 16-month-old boy who presented with a three-day history of febrile morbilliform exanthematous rash associated with confirmed COVID-19 infection. This case presentation serves to expand our knowledge base with respect to the diverse presentations of this highly contagious illness, particularly among pediatric patients. We recommend maintaining a high index of suspicion when evaluating children who present with rash and fever during the current pandemic of COVID-19. Int J Clin Pediatr. 2020;9(4):135-137 doi: https://doi.org/10.14740/ijcp408","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"11 1","pages":"135-137"},"PeriodicalIF":0.0,"publicationDate":"2020-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83363290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Perineal Groove in a Neonate With Increased Maternal Serum Alpha-Fetoprotein 母亲血清甲胎蛋白增高的新生儿会阴沟

International Journal of Clinical Pediatrics Pub Date : 2020-11-04 DOI: 10.14740/ijcp383

Jameson M Petrochko, J. Canning, C. A. Wheeler

引用次数: 0