International Journal of Clinical Pediatrics最新文献

{"title":"X-Linked Lymphoproliferative Disease Type 2 With Activation of Hemophagocytic Lymphohistiocytosis Secondary to Epstein-Barr Virus Infection","authors":"Shahad Alsheikh, Noor Alsheikh, Mona AlSaleh","doi":"10.14740/ijcp525","DOIUrl":"https://doi.org/10.14740/ijcp525","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"332 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnets Playing Hide and Seek: A Case Report of Hidden Magnets in a Child","authors":"Yasir Ahmed, Pooneh Farhangi, Ibrar Atiq, Fahad Malik, Gregory Scagnelli","doi":"10.14740/ijcp532","DOIUrl":"https://doi.org/10.14740/ijcp532","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"48 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141142051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prothrombin Complex Concentrate to Treat Coagulation Disturbances in Pediatric Patients With Intracranial Pathology Including Traumatic Brain Injury","authors":"Collin Reeves, Eric A. Sribnick, Joseph D. Tobias","doi":"10.14740/ijcp527","DOIUrl":"https://doi.org/10.14740/ijcp527","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141141790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimizing Risk Associated With Vitamin K Deficiency Bleeding During Ankyloglossia Release of Infants","authors":"Crystal Robyn Abramczyk, Joyce Pye Funston, Jessica Hartson Morse, Robert A. Convissar","doi":"10.14740/ijcp526","DOIUrl":"https://doi.org/10.14740/ijcp526","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"32 33","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141137281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Effectiveness of Online Versus Offline Parent-Mediated Therapeutic Intervention in Preschool Children With Autism Spectrum Disorder","authors":"Luna Bajracharya, Praveen Suman, Imran Mushtaq","doi":"10.14740/ijcp538","DOIUrl":"https://doi.org/10.14740/ijcp538","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":" 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141132018","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Severe Unexpected Hyponatremia in an Infant With Cystic Fibrosis Carriership","authors":"Simone de Milliano, Nasser E. Ajubi, Farah A. Falix","doi":"10.14740/ijcp516","DOIUrl":"https://doi.org/10.14740/ijcp516","url":null,"abstract":"This report describes the development of severe hyponatremia in a 4-month-old infant, with known carriership of cystic fibrosis (CF; heterozygous delta F508 cystic fibrosis transmembrane conductance regulator (CFTR) mutation), in the course of a coronavirus disease 2019 (COVID-19) infection with mild respiratory symptoms and a urinary tract infection. Laboratory investigations were performed in the outpatient clinic because of persistent loss of appetite, fussiness and mild weight loss after a recent antibiotically treated urinary tract infection. The results showed severe hyponatremia of 115 mmol/L, mild hypokalemia of 3.0 mmol/L, with normal renal function, without other biochemical signs of dehydration and neither signs of fluid retention. Urinary fractional sodium excretion was extremely low, indicative of adequate renal sodium retention in the hyponatremic state. We hypothesize that the combination of disturbed extrarenal salt losses due to CF carriership, together with loss of appetite, relatively low sodium content of breastmilk and possibly COVID-19-associated mild syndrome of inappropriate antidiuretic hormone secretion (SIADH), resulted in the severe hyponatremia that was found in this infant. We believe it is important to report the findings in the current case to underscore the intricate balance of sodium homeostasis in the fully breastfed older infant and the alertness for checking sodium levels during infections/illness in heterozygote CF patients, as was previously reported in literature. In conclusion, this report describes the development of severe unexpected hyponatremia in the course of a mild infectious period in a fully breastfed 4-month-old infant with known CF carriership and underscores the importance of measuring sodium levels with low threshold during infections in CF carriers. Int J Clin Pediatr. 2023;12(2):45-50 doi: https://doi.org/10.14740/ijcp516","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Experience With a Continuous Lidocaine Infusion as an Analgesia Adjunct for Acute Pain Management Following Surgery in Pediatric Patients","authors":"Deanna F. Couser, Catherine Roth, Miranda Holbrook, Sibelle Aurelie Yemele Kitio, Sharon Wrona, David Martin, Joseph D. Tobias","doi":"10.14740/ijcp522","DOIUrl":"https://doi.org/10.14740/ijcp522","url":null,"abstract":"Background: Lidocaine is a local anesthetic of the amide class that has been used for various therapeutic interventions. Its potential analgesic effects have been reported in anecdotal reports and larger clinical trials. Methods: We retrospectively reviewed our 24-month experience with the use of lidocaine outside of the intensive care unit (ICU) setting as an adjunct to acute pain management following major surgical procedures in children and adolescents. Results: The study cohort included 168 patients (mean age 13.8 years). The majority of patients (N = 142) underwent a posterior spinal fusion for treatment of scoliosis (idiopathic or neuromuscular). Thirty-one patients received a bolus dose followed by an infusion starting at 0.2 to 2 mg/kg/h (average dose 0.97 mg/kg/h). Most patients (86.3%) received a continuous lidocaine infusion for 1 - 3 days at an average dose of 1 mg/kg/h. Lidocaine was infused for a total of 503 days in the study cohort of 168 patients. Despite that these were major surgical procedures, pain scores were generally acceptable. The lidocaine infusion was discontinued or decreased in eight patients due to concerns of adverse effects. Adverse effects were noted in 38 days of the 503 days of infusion (7.6%). A total of 29 patients (17.3%) experienced at least one adverse effect. The majority of these were related to the central nervous system (CNS) including blurred vision, dizziness, drowsiness/difficult to arouse, delirium, hallucinations, agitation, confusion, delirium, hallucinations, agitation, and confusion. Conclusions: We present the largest study to date outlining the use of lidocaine as an adjunct to acute pain management in children and adolescents. These preliminary data suggest that with enhanced clinical observation for signs of potential toxicity and increased clinical monitoring of vital signs, the lidocaine infusion can be administered on the inpatient ward without routine serum concentration monitoring. The current cohort and other studies in pediatric patients provide a background for prospective studies to evaluate dosing regimens, optimal patient populations, and analgesic efficacy. Int J Clin Pediatr. 2023;12(2):29-36 doi: https://doi.org/10.14740/ijcp522","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"169 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hallucinations in a Toddler Following Topiramate Intoxication","authors":"Andrew Shieh, Natalie Schellpfeffer","doi":"10.14740/ijcp514","DOIUrl":"https://doi.org/10.14740/ijcp514","url":null,"abstract":"Topiramate is a common anticonvulsant medication used to treat seizures. We describe a 3-year-old boy who unintentionally ingested an unknown amount of topiramate tablets and soon after, was found to have strange behavior. He experienced visual hallucinations with evolving neurologic abnormalities including incoherence, confusion, and delirium. After 1 day from the suspected time of ingestion, the child had completely recovered without medical intervention and experienced no permanent neurologic sequelae. Topiramate ingestion is a rare cause of hallucinations in children and should be suspected in children who present with altered mental status and mild metabolic acidosis. Int J Clin Pediatr. 2023;12(2):51-54 doi: https://doi.org/10.14740/ijcp514","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134961196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are the Reference Equations for Maximal Respiratory Pressure in Children Adequately Predicting Their Value?","authors":"Natalia Marcolin, Pedro Dal Lago, Jaksoel Cunha Silva, Jenifer Dos Santos, Luana Cefora Godoy Silva, Simone Dal Corso, Fernanda Cordoba Lanza","doi":"10.14740/ijcp517","DOIUrl":"https://doi.org/10.14740/ijcp517","url":null,"abstract":"Background: This study aimed to investigate the agreement between the measured and estimated respiratory muscle strength in children and adolescents. We hypothesized that when using reference muscle strength equation consistent with the characteristics of the sample population, there would not be differences between the measured and predicted values. Methods: This was a cross-sectional study. One hundred seventy-nine participants were healthy volunteers between 6 and 18 years of age. Those who had lung disease in the previous 4 weeks, abnormalities in the pulmonary function test, chronic cardiopulmonary disease, prematurity or inadequacy when performing the tests were excluded. Maximal inspiratory and expiratory pressures (MIP and MEP) were assessed according to recommendations. The measured MIP and MEP values were compared to predicted values of the six most frequently cited prediction equations for children and adolescents. Results: Mean age was 12.3 +/- 3.7 years and 54% were male. The mean MIP was 87.5 +/- 27.1 cm H 2 O and MEP was 90.8 +/- 23.6 cm H 2 O. Three predicted MIP equations had similar results to the measured values (P > 0.05). For MEP, only one equation had similar values (P = 0.12). Instead, there was weak to moderate agreement of all equations. At Bland-Altman plots, the mean bias was greater than 6 cm H 2 O for all equations, and the 95% confidence interval (CI) was about 30 cm H 2 O. Conclusion: There is significant variability between measured and predicted MIP and MEP values. Some equations showed similarity to measured values; however, the reliability was poor. Int J Clin Pediatr. 2023;12(2):37-44 doi: https://doi.org/10.14740/ijcp517","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134960907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foot Drop Following Epidural Catheter Placement for Postoperative Analgesia Following Lower Extremity Orthopedic Surgery in an Adolescent: Investigation and Etiology","authors":"Amr Elhamrawy, J. Tobias, G. Veneziano","doi":"10.14740/ijcp513","DOIUrl":"https://doi.org/10.14740/ijcp513","url":null,"abstract":"","PeriodicalId":13773,"journal":{"name":"International Journal of Clinical Pediatrics","volume":"2 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89784017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}