Hallucinations in a Toddler Following Topiramate Intoxication

Andrew Shieh, Natalie Schellpfeffer
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Abstract

Topiramate is a common anticonvulsant medication used to treat seizures. We describe a 3-year-old boy who unintentionally ingested an unknown amount of topiramate tablets and soon after, was found to have strange behavior. He experienced visual hallucinations with evolving neurologic abnormalities including incoherence, confusion, and delirium. After 1 day from the suspected time of ingestion, the child had completely recovered without medical intervention and experienced no permanent neurologic sequelae. Topiramate ingestion is a rare cause of hallucinations in children and should be suspected in children who present with altered mental status and mild metabolic acidosis. Int J Clin Pediatr. 2023;12(2):51-54 doi: https://doi.org/10.14740/ijcp514
托吡酯中毒后幼儿的幻觉
托吡酯是一种常用的抗惊厥药物,用于治疗癫痫发作。我们描述了一个3岁的男孩,他无意中摄入了未知数量的托吡酯片,不久之后,被发现有奇怪的行为。他出现了视觉幻觉,并伴有神经系统异常,包括语无条理、思维混乱和谵妄。疑似误食1天后,患儿完全康复,无需药物干预,无永久性神经系统后遗症。摄取托吡酯是儿童出现幻觉的罕见原因,在出现精神状态改变和轻度代谢性酸中毒的儿童中应加以怀疑。国际儿科临床杂志。2023;12(2):51-54 doi: https://doi.org/10.14740/ijcp514
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