Scientific Inquiry and Review最新文献_第4页

Sources and Chemistry of Flavonoids; their Biological and Therapeutic Potential 黄酮类化合物的来源及化学性质它们的生物学和治疗潜力

Scientific Inquiry and Review Pub Date : 2022-06-15 DOI: 10.32350/sir.62.03

Dr Shabbir Hussain, Waqar Mirza, Mufliha Murtaza, Ansa Nazir, I. Hanif, Muhammad Ahmad

{"title":"Sources and Chemistry of Flavonoids; their Biological and Therapeutic Potential","authors":"Dr Shabbir Hussain, Waqar Mirza, Mufliha Murtaza, Ansa Nazir, I. Hanif, Muhammad Ahmad","doi":"10.32350/sir.62.03","DOIUrl":"https://doi.org/10.32350/sir.62.03","url":null,"abstract":"Flavonoids are natural polyphenolic compounds, which are responsible for the taste and colors of medicinal plants, herbs, fruits, vegetables. Fruits (e.g., Berries, cherries, plums, apples, lemons, oranges, and grapes etc) and vegetables (e.g., broad beans, olives, onions, spinach, shallot etc) are the main sources of flavonoids. They also exist abundantly in cocoa products, black and green tea, red wine, red pepper, chamomile, celery, parsley, ginkgo, and mint. Flavonoids derivatives can also be synthesized through esterification, halogenation, alkoxylation, alkylation, aromatic hydroxylation, acylation and conjugation with various organic compounds. Flavonoids can be supplemented in a staple of food as nutraceutical agents and have an important role in human diet. They possess diverse biological activities including anti-inflammation, anti-oxidation, anti-cancer, anti-diabetes, anti-obesity, antimutagenic, neuroprotective and also have beneficial effects on oxidative stress, inflammation, insulin resistance, lipid metabolism and neurodegenerative diseases (e.g., amyotrophic lateral sclerosis, Huntington’s disease, Parkinson’s disease and Alzheimer’s disease). Flavonoids contain a 15-carbon skeleton; the basic structure consists of a flavan nucleus, a combination of two benzene and one pyran rings. Flavonoids are divided into eight important groups i.e., flavones, flavanols, isoflavones, flavan-3-ols, flavanonols, anthocyanidins, chalcones, and flavanones. A structure-activity relationship exists between flavonoids and their antioxidant activities. Flavonoids are effective in chelating metal ions and scavenging free radicals. The antioxidant properties of flavonoids are governed by their –OH groups, differences in hydrophobicity and molecular planarity.","PeriodicalId":137307,"journal":{"name":"Scientific Inquiry and Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127029496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Solution of Volterra integral equations of the 2nd kind with bulge function using Aboodh transform 用Aboodh变换求解第二类带凸函数的Volterra积分方程

Scientific Inquiry and Review Pub Date : 2022-06-10 DOI: 10.32350/sir.62.02

Asif Iqbal Ali, Muhammad Kalim, Adnan Khan

引用次数: 0

Double Moving Average Control Chart for Autocorrelated Data 自相关数据的双移动平均控制图

Scientific Inquiry and Review Pub Date : 2022-06-01 DOI: 10.32350/sir.62.01

Hira Arooj, K. Malik

{"title":"Double Moving Average Control Chart for Autocorrelated Data","authors":"Hira Arooj, K. Malik","doi":"10.32350/sir.62.01","DOIUrl":"https://doi.org/10.32350/sir.62.01","url":null,"abstract":"The assumption of normality and independence is necessary for statistical inference of control charts. Misleading results are obtained if the traditional control chart technique is applied on the auto-correlated data. When data is correlated, a time series model is employed to produce an optimum output. The objective is to create a new control chart methodology that takes the autocorrelation of observations into account. Charts of Moving Average, Exponentially Weighted and Cumulative Sum better perform in the existence of autocorrelation data for small and moderate changes. The proposed methodology is highly skilled and receptive to minor, moderate and major changes in the process. Propsed DMA chart increases efficiency of average run length (ARL) chart for moving average (MA) to detect the small to medium magnitude shifts in the mean. The simulation also demonstrates that the DMA chart with spans of w=10 and 15 generally performs well in terms of average run length (ARL) as compared to clasical MA. This research may be extended to a multivariate autocorrelated statistical process control, but it can also be used to recognise and categorise seven categories of traditional control chart patterns, such as Downward, Upward Shift, Normal Trend, Cyclic, Systematic patterns, Increasing and Decresing Trend. In order to identify and categorize a set of subclasses of abnormal patterns, this model (multivariate autocorrelated statistical process control chart) should employ a multilayer feed forward Artificial Neural Network (ANN) architecture controlled by a back-propagation learning rule.","PeriodicalId":137307,"journal":{"name":"Scientific Inquiry and Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116562887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Statistically Convergent Sequences in Neutrosophic Metric Spaces 中性度量空间中的统计收敛序列

Scientific Inquiry and Review Pub Date : 2022-03-30 DOI: 10.32350/sir.61.03

Usman Ali, Umar Ishtiaq, Khaleel Ahmad, Jahanzaib

引用次数: 1

General Construction of Efficient Circular Weakly Balanced Repeated Measurements Designs 有效圆形弱平衡重复测量设计的一般构造

Scientific Inquiry and Review Pub Date : 2022-03-30 DOI: 10.32350/sir.61.05

Q. Mehmood, Kashif Rasheed, Khadija Noreen, Rashid Ahmed, Berihan R. Elemary

引用次数: 0

Operational Matrix of Fractional Order Integration and Its Application to Solve Fractional Differential Equations (FDEs) Using Haar Wavelet Collocation Method (HWCM) 分数阶积分的运算矩阵及其在Haar小波配置法求解分数阶微分方程中的应用

Scientific Inquiry and Review Pub Date : 2022-03-30 DOI: 10.32350/sir.61.04

A. Deshi, G. A. Gudodagi

引用次数: 0

Implementation of Lengyel-Epstein Reaction Model for Zinc Oxide (ZnO) Nanostructures by Comparing Euler and Fourth-Order Runge–Kutta (RK) Methods 用欧拉和四阶龙格-库塔(RK)方法比较氧化锌纳米结构的lengye - epstein反应模型

Scientific Inquiry and Review Pub Date : 2022-03-30 DOI: 10.32350/sir.61.02

Kaniz Fatima, Basit Ali, Mahnoor

引用次数: 0

Application of Univariate Probability Distributions Fitting With Monte Carlo Simulation 蒙特卡罗模拟在单变量概率分布拟合中的应用

Scientific Inquiry and Review Pub Date : 2022-01-13 DOI: 10.32350/sir.54.02

Muhammad Ilyas, Shaheen Abbas, Afzal Ali

{"title":"Application of Univariate Probability Distributions Fitting With Monte Carlo Simulation","authors":"Muhammad Ilyas, Shaheen Abbas, Afzal Ali","doi":"10.32350/sir.54.02","DOIUrl":"https://doi.org/10.32350/sir.54.02","url":null,"abstract":"In this study, we present a univariate probability distribution through application of the three Sub and Super Exponential heavier-longer and lighter-shorter tails fitting. This univariate family includes the Lognormal, Gamma and Weibull distribution, the adequacy of the distribution tails is obtained by adequate Fitting Tests and descriptive Criterion. It emphasizes on tail values and is independent of the number of intervals. In this regards the time series analysis for the last three centuries of the logarithm population data sets over to Karachi region (from1729 to1946 and from 1951 to 2018) is used, which contains irregular and regular length and peaks, That peaks /tails fitting is attained by methods for validation and normality tests and defined by stochastic depiction. In other hand, Weibull and Lognormal distribution tails are found as heavier distribution by two validation tests (Maximum Likelihood Estimation and probability of correct selection), In the final section, the univariate probability distributions are used to Monte Carlo simulation for generating the actual population data, it indicates that the heavy-tailed Lognormal and Weibull distributions are also fitted contract than the more commonly seen lighter tailed Gamma distribution. So, the Monte Carlo Simulation performs the appropriate Lognormal and Weibull distributions for irregular and regular data and generate data values (298 and 69) from duration of 1729 to 2020 and 1951 to 2020. \u0000Copyright(c) The Author","PeriodicalId":137307,"journal":{"name":"Scientific Inquiry and Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132294814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis of Trimetallic Oxides of Mn, Cu, Zn Using Rose Petals and their Antimicrobial Activity 玫瑰花瓣绿色合成锰、铜、锌三金属氧化物及其抑菌活性

Scientific Inquiry and Review Pub Date : 2021-12-30 DOI: 10.32350/sir.54.05

S. S. Gillani, S. Khan, R. Nazir, A. Qurashi

{"title":"Green Synthesis of Trimetallic Oxides of Mn, Cu, Zn Using Rose Petals and their Antimicrobial Activity","authors":"S. S. Gillani, S. Khan, R. Nazir, A. Qurashi","doi":"10.32350/sir.54.05","DOIUrl":"https://doi.org/10.32350/sir.54.05","url":null,"abstract":"Mixed metal oxides (CuO, ZnO, and MnO) nanoparticles (NPs) were synthesized by the green process which is simple, cost-effective, eco-friendly, and non-toxic. In the green synthesis method, rose petals extracts were used as a reducing and capping agent while salt solutions (CuCl2, MnCl2, and ZnSO4) were used as a precursor that lead to the formation of mixed metal oxides (CuO, ZnO, MnO) NPs. UV-Visible and FTIR spectroscopy were used for the analysis of mixed metal oxides (CuO, ZnO, MnO) NPs, which showed maximum absorbance in the range of 280 to 370 nm. The presence of particular peaks in FTIR verified the synthesis of mixed metal oxide nanoparticles. The antimicrobial and antifungal activities of mixed metal oxides (CuO, ZnO, MnO) NPs were carried out by the disc diffusion method and well diffusion method. Mixed metal oxides (CuO, ZnO, MnO) NPs showed antimicrobial activity against Escherichia coli and antifungal activity against Candida albicans, Curvularia lunata, Aspergillus niger, and Trichophyton simii. So, these mixed metal oxides (CuO, ZnO, MnO) NPs can be effective in the pharmaceutical sector. \u0000Keywords: antifungal, antimicrobial, green synthesis, mixed metal oxides nanoparticles (MONPs), rose petals extracts \u0000Copyright (c) The Authors","PeriodicalId":137307,"journal":{"name":"Scientific Inquiry and Review","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125422668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Numerical Solution with Non-Polynomial Cubic Spline Technique of Order Four Homogeneous Parabolic Partial Differential Equations 四阶齐次抛物型偏微分方程的非多项式三次样条法数值解

Scientific Inquiry and Review Pub Date : 2021-12-27 DOI: 10.32350/sir.54.03

Bilal Ahmad, Anjum Perviz, M. O. Ahmad, F. Dayan

引用次数: 2