International Cancer Conference Journal最新文献_第9页

Local recurrence of breast cancer histologically resembling Paget disease presumably due to needle tract seeding: a case report. 推测为针道播种导致组织学上类似帕吉特病的乳腺癌局部复发：病例报告。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-02-20 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-023-00594-x

Azusa Terasaki, Hiroko Bando, Aya Ueda, Mai Okazaki, Sachie Hashimoto, Akiko Iguchi-Manaka, Yuzuru Kondo, Hisato Hara

{"title":"Local recurrence of breast cancer histologically resembling Paget disease presumably due to needle tract seeding: a case report.","authors":"Azusa Terasaki, Hiroko Bando, Aya Ueda, Mai Okazaki, Sachie Hashimoto, Akiko Iguchi-Manaka, Yuzuru Kondo, Hisato Hara","doi":"10.1007/s13691-023-00594-x","DOIUrl":"10.1007/s13691-023-00594-x","url":null,"abstract":"Seeding of cancer cells along the needle tract during core needle biopsy is a well-known phenomenon, with a reported frequency of between 22 and 50% [Hoorntje et al. in Eur J Surg Oncol 30:520-525, 2004;Liebens et al. in Maturitas 62:113-123, 2009;Diaz et al. in AJR Am J Roentgenol 173:1303-1313, 1999;]. Local recurrence due to needle tract seeding is rare because the immune system eliminates the cancer cells in most cases. In addition, most local recurrences due to needle tract seeding occur as invasive carcinoma after diagnosis of invasive ductal carcinoma of the breast or mucinous carcinoma, and needle tract seeding due to noninvasive carcinoma is uncommon. We herein report a rare case of local breast cancer recurrence histologically resembling Paget disease, presumably due to needle tract seeding after core needle biopsy for diagnosis of ductal carcinoma in situ of the breast. After receiving a diagnosis of ductal carcinoma in situ, the patient underwent skin-sparing mastectomy and breast reconstruction with a latissimus dorsi musculocutaneous flap. The pathological study showed ER/PgR-negative ductal carcinoma in situ, and no postoperative radiation therapy or systemic therapy was administered. Six months after the surgery, the patient had a breast cancer recurrence histologically resembling Paget disease, presumably in the scar of her core needle biopsy. The pathological study showed Paget disease localized in the epidermis, no invasive carcinoma, and no lymph node metastasis. It was morphologically similar to the primary lesion and was diagnosed as a local recurrence due to needle tract seeding.","PeriodicalId":13703,"journal":{"name":"International Cancer Conference Journal","volume":"12 2","pages":"143-148"},"PeriodicalIF":0.7,"publicationDate":"2023-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989070/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9086356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rhabdomyosarcoma mimicking lymphoma. 模拟淋巴瘤的横纹肌肉瘤

IF 0.7

International Cancer Conference Journal Pub Date : 2023-02-01 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-023-00595-w

Marziyeh Ghalamkari, Mahdi Khatuni, Haniyeh Radkhah, Saeed Farzanehfar, Behnaz Jahanbin

引用次数: 0

Total pancreatectomy preserving the right gastroepiploic artery following proximal gastrectomy. 近端胃切除术后保留右胃上动脉的全胰腺切除术。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-23 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-023-00596-9

Kyohei Yugawa, Naoto Kojo, Shohei Yamaguchi, Shigeyuki Nagata, Takashi Maeda

引用次数: 0

ATM mutation in aggressive uterine adenosarcoma in which systemic chemotherapies had remarkable effects. 全身化疗效果显著的侵袭性子宫腺肉瘤中的 ATM 突变。

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International Cancer Conference Journal Pub Date : 2023-01-12 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-022-00591-6

Misaki Koyama, Ken Yamaguchi, Yoshitsugu Chigusa, Koji Yamanoi, Mana Taki, Masumi Sunada, Akihito Horie, Junzo Hamanishi, Sachiko Minamiguchi, Masaki Mandai

引用次数: 0

A case of advanced breast cancer with Gitelman syndrome. 一例晚期乳腺癌合并吉特曼综合征。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-04 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-022-00593-4

Yuko Tanaka, Miyuki Muramatsu, Yoshihiro Miyauchi, Yoshio Suzuki, Tamaki Morohashi, Kandai Nozu

引用次数: 0

Interstitial pneumonia after regression by olaparib for neuroendocrine prostate cancer with BRCA1 mutation: a case report. 奥拉帕尼治疗 BRCA1 基因突变的神经内分泌性前列腺癌后的间质性肺炎：病例报告。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-03 eCollection Date: 2023-04-01 DOI: 10.1007/s13691-022-00592-5

Masashi Kaitsumaru, Masaki Shiota, Dai Takamatsu, Leandro Blas, Takashi Matsumoto, Junichi Inokuchi, Yoshinao Oda, Masatoshi Eto

引用次数: 0

Lenvatinib-refractory thymic mucinous carcinoma with PIK3CA mutation. lenvatinib难治性胸腺粘液癌伴PIK3CA突变。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-01 DOI: 10.1007/s13691-022-00573-8

Akihiro Tsukaguchi, Shoichi Ihara, Hironao Yasuoka, Seigo Minami

{"title":"Lenvatinib-refractory thymic mucinous carcinoma with PIK3CA mutation.","authors":"Akihiro Tsukaguchi, Shoichi Ihara, Hironao Yasuoka, Seigo Minami","doi":"10.1007/s13691-022-00573-8","DOIUrl":"https://doi.org/10.1007/s13691-022-00573-8","url":null,"abstract":"Mucinous adenocarcinoma, a very rare type of thymic carcinoma, is aggressive and has a poor prognosis. The optimal treatment for advanced thymic mucinous adenocarcinoma has not yet been established because of its rarity. An oral multi-tyrosine kinase inhibitor, lenvatinib, was approved for treatment of thymic carcinoma in March 2021 in Japan. However, to the best of our knowledge, there are no published reports concerning lenvatinib for thymic mucinous adenocarcinoma. Herein, we report a 39-year-old woman who presented with a 70 mm multilocular cystic tumor in her left anterior mediastinum and a massive pericardial effusion. We diagnosed a Masaoka stage IVb thymic mucinous adenocarcinoma with multiple metastases to the liver and bones, and pericardial dissemination on the basis of the pathologic findings on examination of a video-assisted thoracoscopic tumor biopsy and radiological examinations. She received paclitaxel-carboplatin-based chemotherapy, but developed a left cerebellar metastasis. Second-line chemotherapy with lenvatinib failed to suppress the tumor. She died of cancer progression 5 months after presentation. Here, we report what we believe to be the first case of a thymic mucinous adenocarcinoma treated with lenvatinib. Our patient's thymic mucinous adenocarcinoma was refractory to both cytotoxic chemotherapy and lenvatinib. Using next-generation sequencing, we identified phosphatidylinositol 3-kinase catalytic subunit alpha mutation in the tumor. We suspected an association between this mutation and resistance to lenvatinib. We therefore recommend performing next-generation sequencing when considering introduction of lenvatinib for thymic mucinous adenocarcinoma. A surgical procedure may be necessary for accurate diagnosis and genetic analysis of this histological tumor type.","PeriodicalId":13703,"journal":{"name":"International Cancer Conference Journal","volume":"12 1","pages":"36-40"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807735/pdf/13691_2022_Article_573.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10037866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid-onset paraneoplastic cerebellar degeneration successfully treated by radiotherapy and tumorectomy. 快速发作的副肿瘤小脑变性经放疗和肿瘤切除术成功治疗。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-01 DOI: 10.1007/s13691-022-00569-4

Philippe Westerlinck, Nicolas Janin, Philippe Coucke

{"title":"Rapid-onset paraneoplastic cerebellar degeneration successfully treated by radiotherapy and tumorectomy.","authors":"Philippe Westerlinck, Nicolas Janin, Philippe Coucke","doi":"10.1007/s13691-022-00569-4","DOIUrl":"https://doi.org/10.1007/s13691-022-00569-4","url":null,"abstract":"We report the first-ever documented case of successful treatment of paraneoplastic cerebellar degeneration (PCD) with radiotherapy. A 31-year-old female presented with rapidly progressing neurological symptoms, which were revealed to be due to PCD secondary to an undiagnosed breast cancer. The cancer responded well to chemotherapy, but her neurological status continued to deteriorate, eventually progressing to complete expressive aphasia and dyssynergia with paraparesis. Due to the extraordinarily rapid progression of the disorder, a treatment with tumorectomy and radiotherapy of the whole brain was performed. This proved to be very successful, with a complete stop of the deterioration of symptoms after treatment and with a significant neurologic improvement in the following months. This case indicates that there may be a place for radiotherapy in the treatment of PCD. Current treatment options have proven insufficient and no guidelines for treatment currently exist. As such, the disorder remains associated with a very poor prognosis and often entails permanent loss of function. Radiation, with its known immunosuppressive effect and non-stochastic effects on the nervous system at the proper doses, might therefore be a valid option. However, we should note that it was in this instance combined with a removal of the primary tumor and as such, its individual efficacy cannot be considered proven.","PeriodicalId":13703,"journal":{"name":"International Cancer Conference Journal","volume":"12 1","pages":"19-23"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807696/pdf/13691_2022_Article_569.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9933693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Systemic chemotherapy for unresectable or recurrent primary thymic adenocarcinoma of enteric type. 不可切除或复发的肠型原发性胸腺癌的全身化疗。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-01 DOI: 10.1007/s13691-022-00575-6

Xiaofang Gao

引用次数: 0

Antemortem diagnosis of pulmonary tumor thrombotic microangiopathy associated with gastric cancer and response to immediate chemotherapy. 胃癌相关肺肿瘤血栓性微血管病变的死前诊断及对即刻化疗的反应。

IF 0.7

International Cancer Conference Journal Pub Date : 2023-01-01 DOI: 10.1007/s13691-022-00566-7

Kohei Fujita, Takeshi Omori, Hisashi Hara, Naoki Shinno, Masaaki Yamamoto, Takashi Kanemura, Tomohira Takeoka, Takahito Sugase, Hiroshi Miyata, Masayuki Ohue, Masato Sakon

{"title":"Antemortem diagnosis of pulmonary tumor thrombotic microangiopathy associated with gastric cancer and response to immediate chemotherapy.","authors":"Kohei Fujita, Takeshi Omori, Hisashi Hara, Naoki Shinno, Masaaki Yamamoto, Takashi Kanemura, Tomohira Takeoka, Takahito Sugase, Hiroshi Miyata, Masayuki Ohue, Masato Sakon","doi":"10.1007/s13691-022-00566-7","DOIUrl":"https://doi.org/10.1007/s13691-022-00566-7","url":null,"abstract":"Pulmonary tumor thrombotic microangiopathy is a rare and fatal complication of cancer that features widespread tumor cell-derived embolisms in the small arteries and arterioles of the lung and is often associated with thrombus formation. We describe the case of a 43-year-old woman who was hospitalized with cough and respiratory distress that lasted for 2 months. Computed tomography findings demonstrated multiple areas of interlobular septal thickening and ground-glass opacities in both lungs. Transthoracic echocardiography demonstrated a D-shaped left ventricle suggesting right heart overload, and pulmonary blood flow scintigraphy revealed multiple small, peripheral, and patchy areas of reduced blood flow. Upper gastrointestinal endoscopy revealed a signet-ring carcinoma. The patient was diagnosed with pulmonary tumor thrombotic microangiopathy based on her clinical presentation and treatment with tegafur, gimeracil oteracil potassium, oxaliplatin, and an anticoagulant was initiated on the 3rd day after admission. The symptoms improved rapidly after treatment initiation. The patient was discharged 28 days after initiation of chemotherapy without the need for supplemental oxygen. This case suggests that the immediate use of chemotherapy and anticoagulants for treating pulmonary tumor thrombotic microangiopathy may improve patient survival.","PeriodicalId":13703,"journal":{"name":"International Cancer Conference Journal","volume":"12 1","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807729/pdf/13691_2022_Article_566.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9890984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0