British Journal of Surgery最新文献

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Resection of multifocal intrahepatic cholangiocarcinoma. 多灶性肝内胆管癌切除术。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf048
Kjetil Søreide
{"title":"Resection of multifocal intrahepatic cholangiocarcinoma.","authors":"Kjetil Søreide","doi":"10.1093/bjs/znaf048","DOIUrl":"10.1093/bjs/znaf048","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laparoscopic in situ anatomical resection of posterosuperior liver segments: preservation of segment 6 regardless of the presence of the inferior right hepatic vein. 腹腔镜下肝后上段原位解剖切除术:保留第6段,不论是否存在右肝下静脉。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf066
Xingru Wang, Jiahong Liang, Li Cao, Yixuan Liu, Jianwei Li
{"title":"Laparoscopic in situ anatomical resection of posterosuperior liver segments: preservation of segment 6 regardless of the presence of the inferior right hepatic vein.","authors":"Xingru Wang, Jiahong Liang, Li Cao, Yixuan Liu, Jianwei Li","doi":"10.1093/bjs/znaf066","DOIUrl":"https://doi.org/10.1093/bjs/znaf066","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study. 病理反应指导5-氟尿嘧啶、亚叶酸钙、奥沙利铂和多西紫杉醇(FLOT)辅助化疗手术切除胃食管癌(SPACE-FLOT):国际队列研究。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf056
{"title":"Pathological response guides adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy in surgically resected gastro-oesophageal cancer (SPACE-FLOT): international cohort study.","authors":"","doi":"10.1093/bjs/znaf056","DOIUrl":"10.1093/bjs/znaf056","url":null,"abstract":"<p><strong>Background: </strong>Many patients with locally advanced gastro-oesophageal cancers are unable to complete adjuvant 5-fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT) chemotherapy, raising questions about its therapeutic utility. The aim of this study was to examine whether pathological response to neoadjuvant FLOT can guide its adjuvant use.</p><p><strong>Methods: </strong>Patients with non-metastatic gastro-oesophageal adenocarcinoma who received neoadjuvant FLOT and underwent surgery from 1 January 2017 to 1 January 2022 from 43 hospitals across 12 countries were analysed. Pathological response was assessed using tumour regression grading systems, trichotomized into minimal responders (MR; worst category), complete responders (CR; pCR), and partial responders (PR; between MR and CR). Survival outcomes of patients who did and did not receive adjuvant FLOT were compared using Kaplan-Meier, Cox regression, propensity score matched, and sensitivity analysis.</p><p><strong>Results: </strong>A total of 1887 patients (459 MR, 221 CR, and 1207 PR) were evaluated. The median follow-up was 25.5 (interquartile range 15.0-39.1) months. In the MR group, there was no difference in disease-free survival (DFS; HR 1.03 (95% c.i. 0.78 to 1.36), P = 0.836) between those who did and did not receive adjuvant FLOT. Whilst there was a difference in non-adjusted OS, this became statistically non-significant after adjusting for baseline characteristics (HR 0.96 (95% c.i. 0.70 to 1.30), P = 0.801). In the CR group, there was no difference in DFS (HR 0.88 (95% c.i. 0.41 to 1.85), P = 0.724) or OS (HR 0.69 (95% c.i. 0.31 to 1.54), P = 0.343) between those who did and did not receive adjuvant FLOT. In the PR group, adjuvant FLOT conferred a significant DFS (HR 0.68 (95% c.i. 0.55 to 0.86), P < 0.001) and OS (HR 0.55 (95% c.i. 0.44 to 0.69), P < 0.001) benefit.</p><p><strong>Conclusion: </strong>Pathological response to neoadjuvant FLOT may guide the use of adjuvant FLOT, enabling personalized approaches to treatment.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tranexamic acid for trauma: optimal timing of administration based on the CRASH-2 and CRASH-3 trials. 创伤用氨甲环酸:基于CRASH-2和CRASH-3试验的最佳给药时机。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf079
Itsuki Osawa, Tadahiro Goto, Ian Roberts
{"title":"Tranexamic acid for trauma: optimal timing of administration based on the CRASH-2 and CRASH-3 trials.","authors":"Itsuki Osawa, Tadahiro Goto, Ian Roberts","doi":"10.1093/bjs/znaf079","DOIUrl":"10.1093/bjs/znaf079","url":null,"abstract":"<p><strong>Background: </strong>Tranexamic acid reduces bleeding deaths in trauma patients, but the treatment benefit depends on the time from injury. It is recommended that tranexamic acid be administered immediately and only within 3 h of injury; however, the optimal criteria have not been adequately studied.</p><p><strong>Methods: </strong>We applied machine learning-based causal forest models to investigate heterogeneity in the effects of tranexamic acid on 24-hour mortality rate conditional on covariates (for example age, sex, time from injury, systolic blood pressure, and Glasgow Coma Scale, GCS). We analysed data on 28 448 trauma patients in the CRASH-2 and CRASH-3 randomized trials. We used the policytree algorithm to determine the optimal criteria for tranexamic acid treatment.</p><p><strong>Results: </strong>The causal forest models showed heterogeneity in the effects of tranexamic acid on 24-hour mortality rate. The relative risk reduction was greatest in patients treated within 2 h of injury but thereafter decreased rapidly. The pattern was similar regardless of age or systolic blood pressure, although with decreasing GCS, the time to treatment effects were weaker, with benefits beyond 3 h. The largest absolute risk reductions were in patients with a low blood pressure and a low GCS when treated soon after injury. The optimal criterion was statistically determined as patients within 2 h of the injury or with GCS < 9.</p><p><strong>Conclusions: </strong>Tranexamic acid administration was found to be beneficial when given within 2 h of injury. In patients with severe traumatic brain injury, the treatment benefits may persist beyond the 2-hour window.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database. MLH1、MSH2和MSH6 Lynch综合征患者延长或节段性切除后的异时性结直肠癌风险:来自前瞻性Lynch综合征数据库的多中心研究
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf061
{"title":"Metachronous colorectal cancer risks after extended or segmental resection in MLH1, MSH2, and MSH6 Lynch syndrome: multicentre study from the Prospective Lynch Syndrome Database.","authors":"","doi":"10.1093/bjs/znaf061","DOIUrl":"https://doi.org/10.1093/bjs/znaf061","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11997434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143961557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small bowel obstruction outcomes according to compliance with the World Society of Emergency Surgery Bologna guidelines. 小肠梗阻结果符合世界急诊外科学会博洛尼亚指南。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf080
Lewis J Kaplan, Isidro Martinez-Casas, Shahin Mohseni, Matteo Cimino, Hayato Kurihara, Matthew J Lee, Gary A Bass
{"title":"Small bowel obstruction outcomes according to compliance with the World Society of Emergency Surgery Bologna guidelines.","authors":"Lewis J Kaplan, Isidro Martinez-Casas, Shahin Mohseni, Matteo Cimino, Hayato Kurihara, Matthew J Lee, Gary A Bass","doi":"10.1093/bjs/znaf080","DOIUrl":"https://doi.org/10.1093/bjs/znaf080","url":null,"abstract":"<p><strong>Background: </strong>Small bowel obstruction (SBO) is a common surgical emergency associated with substantial morbidity, hospital length of stay (LOS), and healthcare cost. The World Society of Emergency Surgery (WSES) Bologna guidelines provide evidence-informed recommendations for managing adhesive SBO, promoting timely surgical intervention (or non-operative management (NOM) when ischaemia, strangulation, or peritonitis are absent). However, guideline adoption and its impact on outcomes remain under studied. Compliance with the Bologna guidelines was evaluated to determine the impact of compliance on outcomes.</p><p><strong>Methods: </strong>SnapSBO, a prospective, multicentre, time-bound, observational cohort study, captured data on patients with adhesive SBO across diverse healthcare settings and patient populations. Patient care was categorized into: successful NOM, surgery after an unsuccessful appropriate trial of NOM (NOM-T), and direct to surgery (DTS). Compliance with diagnostic, therapeutic, and postoperative Bologna guideline recommendations was assessed as either complete or partial. Primary outcomes included adherence to the Bologna guidelines, LOS, complications, and the incidence of the composite metric 'optimal outcomes' (LOS ≤5 days, discharge without complications, and no readmission within 30 days).</p><p><strong>Results: </strong>Among 982 patients with adhesive SBO, successful NOM occurred in 561 (57.1%), 224 (22.8%) underwent NOM-T, and 197 (20.1%) proceeded DTS. The mean(s.d.) LOS was 5.3(9.0), 12.9(11.4), and 7.7(8.0) days respectively (P < 0.001). Optimal outcomes were achieved in 61.0%, 16.1%, and 37.6% respectively (P < 0.001) and full guideline compliance was observed in 17.2%, 10.1%, and 0.4% respectively.</p><p><strong>Conclusion: </strong>Patients with adhesive SBO whose care was aligned with the Bologna guidelines had a shorter LOS and a greater incidence of optimal outcomes. Addressing evidence-to-practice gaps through implementation strategies that consider contextual factors will enhance guideline adoption and patient outcomes.</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12005947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of gross extrathyroidal extension to the recurrent laryngeal nerve alone on survival in papillary thyroid carcinoma. 甲状腺外粗延伸到喉返神经对甲状腺乳头状癌存活的影响。
IF 9.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf030
Victoria Harries,Daniel W Scholfield,Alana Eagan,R Michael Tuttle,Ashok R Shaha,Jatin P Shah,Richard J Wong,Snehal G Patel,Ian Ganly
{"title":"Impact of gross extrathyroidal extension to the recurrent laryngeal nerve alone on survival in papillary thyroid carcinoma.","authors":"Victoria Harries,Daniel W Scholfield,Alana Eagan,R Michael Tuttle,Ashok R Shaha,Jatin P Shah,Richard J Wong,Snehal G Patel,Ian Ganly","doi":"10.1093/bjs/znaf030","DOIUrl":"https://doi.org/10.1093/bjs/znaf030","url":null,"abstract":"BACKGROUNDGross extrathyroidal extension (ETE) is one of the most important predictors of survival in papillary thyroid carcinoma (PTC). The aim of this study is to determine the impact of gross ETE to the recurrent laryngeal nerve alone (RLNT4aETE) on survival.METHODSAfter institutional review board approval, adult PTC patients were identified from an institutional database undergoing initial surgery for well-differentiated thyroid carcinoma from 1986 to 2020. Patients were classified as having no gross ETE, gross ETE to strap muscles only (T3bETE), RLNT4aETE, or gross ETE involving other adjacent structures (otherT4aETE). Disease-specific survival (DSS) was calculated using the Kaplan-Meier method and groups were compared using the log-rank test.RESULTSThere were 8030 patients included in the analysis; 7578 patients (94.2%) with no gross ETE, 197 (2.4%) with T3bETE, 40 (0.5%) with RLNT4aETE, and 215 (2.7%) with otherT4aETE. The estimated 10-year DSS for patients with no gross ETE, T3bETE, RLNT4aETE, and otherT4aETE in the whole cohort were 99.2%, 95.7%, 96.9%, and 82.5% respectively (P < 0.0001). After controlling for age, nodal and distant disease stage, RLNT4aETE patients had a similar DSS to T3bETE patients, when compared to no gross ETE patients (HRs 2.91 versus 2.28 respectively). In the ≥55-year-old cohort, the 10-year DSS for patients with no gross ETE, T3bETE, RLNT4aETE, and otherT4aETE were 97.7%, 89.4%, 90.9% and 67.6% respectively.CONCLUSIONRLNT4aETE patients appear to have a similar DSS to T3bETE patients. This highlights the heterogeneity within the current T4a cohort and supports the downstaging of RLNT4aETE patients to the T3b classification.","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"1 1","pages":""},"PeriodicalIF":9.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143819370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation and treatment of ruptured abdominal aortic aneurysm. 腹主动脉瘤破裂的评价与治疗。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf051
Maria Elisabeth Leinweber, Fajar S Rahmaditya, Robert J Hinchliffe
{"title":"Evaluation and treatment of ruptured abdominal aortic aneurysm.","authors":"Maria Elisabeth Leinweber, Fajar S Rahmaditya, Robert J Hinchliffe","doi":"10.1093/bjs/znaf051","DOIUrl":"https://doi.org/10.1093/bjs/znaf051","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of aqueous olanexidine compared with alcohol-based chlorhexidine for surgical skin antisepsis regarding the incidence of surgical-site infections in clean-contaminated surgery: a randomized superiority trial. 水奥兰西定与醇基氯己定用于外科皮肤消毒对清洁污染手术中手术部位感染发生率的影响:一项随机优势试验
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf065
Masashi Takeuchi, Hideaki Obara, Tasuku Furube, Hirofumi Kawakubo, Minoru Kitago, Koji Okabayashi, Hiroto Fujisaki, Junya Aoyama, Yosuke Morimoto, Ryusuke Amemiya, Junichi Sano, Jumpei Nakadai, Rei Goto, Yasunori Sato, Yuko Kitagawa
{"title":"Efficacy of aqueous olanexidine compared with alcohol-based chlorhexidine for surgical skin antisepsis regarding the incidence of surgical-site infections in clean-contaminated surgery: a randomized superiority trial.","authors":"Masashi Takeuchi, Hideaki Obara, Tasuku Furube, Hirofumi Kawakubo, Minoru Kitago, Koji Okabayashi, Hiroto Fujisaki, Junya Aoyama, Yosuke Morimoto, Ryusuke Amemiya, Junichi Sano, Jumpei Nakadai, Rei Goto, Yasunori Sato, Yuko Kitagawa","doi":"10.1093/bjs/znaf065","DOIUrl":"10.1093/bjs/znaf065","url":null,"abstract":"<p><strong>Background: </strong>Surgical-site antisepsis is used to prevent surgical-site infections (SSIs). Although several guidelines have indicated the efficacy of antiseptics, such as chlorhexidine, povidone-iodine, and olanexidine, in reducing the SSI rate, an optimal recommendation is still not established. The aim of this study was to evaluate the efficacy of aqueous olanexidine compared with chlorhexidine-alcohol as the optimal antiseptic for preventing SSI in clean-contaminated surgery.</p><p><strong>Methods: </strong>This multicentre randomized trial for surgical skin antisepsis in clean-contaminated gastrointestinal and hepatobiliary-pancreatic surgeries in five hospitals evaluated the efficacy of olanexidine and chlorhexidine-alcohol. The primary endpoint was 30-day SSI. Secondary outcomes included the occurrence of SSI types, intervention-related toxicity, and reoperation caused by SSI.</p><p><strong>Results: </strong>Overall, 700 patients from five institutions underwent randomization; 347 received olanexidine and 345 received chlorhexidine-alcohol in the full analysis set. The 30-day SSI rate was 12.4% (43 of 347) in the olanexidine group and 13.6% (47 of 345) in the chlorhexidine-alcohol group (adjusted risk ratio (aRR) 0.911 (95% c.i. 0.625 to 1.327); P = 0.626). No significant differences were observed between the groups regarding the secondary outcomes, including the occurrence of superficial incisional SSI, deep incisional SSI, organ/space SSI, and reoperation caused by SSI. Overall adverse effects were seen in two patients (0.58%) in the olanexidine group and in three patients (0.87%) in the chlorhexidine-alcohol group (aRR 0.663 (95% c.i. 0.111 to 3.951)).</p><p><strong>Conclusion: </strong>Olanexidine did not significantly reduce the occurrence of overall SSI compared with chlorhexidine-alcohol. Nevertheless, these findings provide valuable insights for developing novel surgical SSI management protocols.</p><p><strong>Registration number: </strong>UMIN 000049712 (University Hospital Medical Information Network Clinical Trials Registry).</p>","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Words that hurt: addressing the gender gap in surgery. 伤人的话:解决手术中的性别差距。
IF 8.6 1区 医学
British Journal of Surgery Pub Date : 2025-03-28 DOI: 10.1093/bjs/znaf059
Elena Giacomelli, Walter Dorigo, Flavia Ciavarelli, Raffaele Pulli
{"title":"Words that hurt: addressing the gender gap in surgery.","authors":"Elena Giacomelli, Walter Dorigo, Flavia Ciavarelli, Raffaele Pulli","doi":"10.1093/bjs/znaf059","DOIUrl":"https://doi.org/10.1093/bjs/znaf059","url":null,"abstract":"","PeriodicalId":136,"journal":{"name":"British Journal of Surgery","volume":"112 4","pages":""},"PeriodicalIF":8.6,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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