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HIV-AIDS - Updates, Perspectives and Applications [Working Title] 爱滋病-最新情况、展望及应用[暂定标题]
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.5772/intechopen.100820
{"title":"HIV-AIDS - Updates, Perspectives and Applications [Working Title]","authors":"","doi":"10.5772/intechopen.100820","DOIUrl":"https://doi.org/10.5772/intechopen.100820","url":null,"abstract":"","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71001779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SARS-CoV-2 Variants - Two Years After [Working Title] SARS-CoV-2变体-两年后[暂定标题]
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.5772/intechopen.100818
{"title":"SARS-CoV-2 Variants - Two Years After [Working Title]","authors":"","doi":"10.5772/intechopen.100818","DOIUrl":"https://doi.org/10.5772/intechopen.100818","url":null,"abstract":"","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71002092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cabotegravir and Rilpivirine Long-acting Injectable Therapy for Human Immunodeficiency Virus 卡波特韦和利匹韦林长期注射治疗人类免疫缺陷病毒
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.17925/id.2022.1.1.14
C. Jonsson-Oldenbüttel
{"title":"Cabotegravir and Rilpivirine Long-acting Injectable Therapy for Human Immunodeficiency Virus","authors":"C. Jonsson-Oldenbüttel","doi":"10.17925/id.2022.1.1.14","DOIUrl":"https://doi.org/10.17925/id.2022.1.1.14","url":null,"abstract":"<p />","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67593662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Novel Antifungals for the Treatment of Vulvovaginal Candidiasis: Where Are We? 治疗外阴阴道念珠菌病的新型抗真菌药:我们在哪里?
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.17925/id.2022.1.1.16
A. Gamal, A. Kadry, M. Elshaer, M. Ghannoum
{"title":"Novel Antifungals for the Treatment of Vulvovaginal Candidiasis: Where Are We?","authors":"A. Gamal, A. Kadry, M. Elshaer, M. Ghannoum","doi":"10.17925/id.2022.1.1.16","DOIUrl":"https://doi.org/10.17925/id.2022.1.1.16","url":null,"abstract":"Vulvovaginal candidiasis (VVC) is a common health-related issue and the second most common cause of vaginitis. Previously, azole antifungals were the mainstay of VVC treatment. Additionally, boric acid and nystatin have been used topically for management of VVC. Despite being effective and well tolerated by most patients, the use of azoles may be limited in some cases. Currently, two new antifungal agents have received US Food and Drug Administration approval for use in the management of VVC. In this article, we briefly review treatment regimens used for the management of VVC over the past decade, the newly approved agents and their possible clinical application, and future treatment considerations.","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67593708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factors Associated With Resistance to In-Hospital Treatment of Malaria in Angolan Patients 安哥拉疟疾患者对住院治疗的耐药性相关因素
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.1177/11786337221076836
E. Sacomboio, C. S Sebastião, Jurema Luzia Francisco Antonio, Álvaro Kuanzambi Vezo, Daisy Viviana Sebastião Bapolo, Joana Morais
{"title":"Factors Associated With Resistance to In-Hospital Treatment of Malaria in Angolan Patients","authors":"E. Sacomboio, C. S Sebastião, Jurema Luzia Francisco Antonio, Álvaro Kuanzambi Vezo, Daisy Viviana Sebastião Bapolo, Joana Morais","doi":"10.1177/11786337221076836","DOIUrl":"https://doi.org/10.1177/11786337221076836","url":null,"abstract":"Background: Malaria is a public health problem, particularly in low- and middle-income countries. In Angola, it is the leading cause of death, morbidity, and absenteeism from work and school. Objective: To evaluate the social and clinical factors associated with resistance to in-hospital treatment. Methodology: A prospective analytical cross-sectional study with a quantitative approach was conducted including 220 patients with malaria. Results: Of the 220 patients enrolled, the majority were between 21 and 40 years old (72.7%), male (53.6%), of peri-urban areas (47.7%), employees (46.4%), and with high parasitemia levels (57.7%). Of the remaining hospitalized patients (61.4%), 20.9% were resistant to treatment. The resistance risk was higher in patients over 40 years [OR: 5.91 (95% CI: 0.76-45.7), P = .088], from rural regions [OR: 2.48 (95% CI: 0.95-6.48), P = .064], that were unemployed [OR: 1.06 (95% CI: 0.52-2.15), P = .859], presenting high parasitemia [OR: 1.95 (95% CI: 1.02-3.75), P = .043] and who remained hospitalized [OR: 5.28 (95% CI: 0.63-43.1), P = .121]. The risk to develop resistance was lower in patients that were students [OR: 0.04 (95% CI: 0.01-0.37), P = .004], patients who were treated with dipyrone [OR: 0.06 (95% CI: 0.01-0.24), P < .001], metoclopramide [OR: 0.25 (95% CI: 0.09-0.67), P = .006] and ciprofloxacin [OR: 0.22 (95% CI: 0.11-0.44), P < .001]. Conclusion: Treatment with antimalarial drugs as well as the use of adjuvants such as dipyrone, metoclopramide, ciprofloxacin, and diazepam can reduce the chances of developing resistance to malaria treatment, however, it is necessary to carry out further in-depth studies.","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44272421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Long Coronavirus Disease 2019 in Children 2019年儿童长冠状病毒病
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.17925/id.2022.1.1.8
K. Krivchenia
{"title":"Long Coronavirus Disease 2019 in Children","authors":"K. Krivchenia","doi":"10.17925/id.2022.1.1.8","DOIUrl":"https://doi.org/10.17925/id.2022.1.1.8","url":null,"abstract":"<p />","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67593604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dapivirine Vaginal Ring for HIV Prevention in Women in South Africa 南非妇女用达匹维林阴道环预防艾滋病毒
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.17925/id.2022.1.1.26
Katherine Gill, L. Bekker
{"title":"Dapivirine Vaginal Ring for HIV Prevention in Women in South Africa","authors":"Katherine Gill, L. Bekker","doi":"10.17925/id.2022.1.1.26","DOIUrl":"https://doi.org/10.17925/id.2022.1.1.26","url":null,"abstract":"Young women remain disproportionately affected by the HIV epidemic in South Africa. Clinical trials have shown that the dapivirine vaginal ring (DVR) is safe and effective at reducing HIV infection in women. In March 2022, the South African Health Products Regulatory Authority approved the use of the DVR in women aged 18 years and older who are unable or unwilling to use oral pre-exposure prophylaxis, as an additional choice for preventing HIV in women at substantial risk. Modelling studies have suggested that the DVR could have a substantial impact if prioritized for women at substantial risk of HIV or women aged 22–29 years. The licensing of the DVR in South Africa is a milestone event that brings the first long-acting and woman-controlled HIV prevention method another step closer to reaching the people who need it. As South Africa prepares its introduction, it is critical to examine the unmet need for HIV prevention and to review the clinical trial data that led to the DVR's approval.","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67593312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention [Working Title] 细菌性传播感染——新发现、诊断、治疗和预防[暂定标题]
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.5772/intechopen.100799
{"title":"Bacterial Sexually Transmitted Infections - New Findings, Diagnosis, Treatment, and Prevention [Working Title]","authors":"","doi":"10.5772/intechopen.100799","DOIUrl":"https://doi.org/10.5772/intechopen.100799","url":null,"abstract":"","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71001872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influenza - New Approaches [Working Title] 流感-新方法[暂定标题]
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2022-01-01 DOI: 10.5772/intechopen.100800
{"title":"Influenza - New Approaches [Working Title]","authors":"","doi":"10.5772/intechopen.100800","DOIUrl":"https://doi.org/10.5772/intechopen.100800","url":null,"abstract":"","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":"1 1","pages":""},"PeriodicalIF":5.8,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71002039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Examining the Executioners, Influenza Associated Secondary Bacterial Pneumonia 检查刽子手，流感相关继发性细菌性肺炎
IF 5.8 4区 医学
Infectious Diseases Pub Date : 2021-12-22 DOI: 10.5772/intechopen.101666
Timothy R. Borgogna, Jovanka M. Voyich
{"title":"Examining the Executioners, Influenza Associated Secondary Bacterial Pneumonia","authors":"Timothy R. Borgogna, Jovanka M. Voyich","doi":"10.5772/intechopen.101666","DOIUrl":"https://doi.org/10.5772/intechopen.101666","url":null,"abstract":"Influenza infections typically present mild to moderate morbidities in immunocompetent host and are often resolved within 14 days of infection onset. Death from influenza infection alone is uncommon; however, antecedent influenza infection often leads to an increased susceptibility to secondary bacterial pneumonia. Bacterial pneumonia following viral infection exhibits mortality rates greater than 10-fold of those of influenza alone. Furthermore, bacterial pneumonia has been identified as the major contributor to mortality during each of the previous four influenza pandemics. Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Streptococcus pyogenes are the most prevalent participants in this pathology. Of note, these lung pathogens are frequently found as commensals of the upper respiratory tract. Herein we describe influenza-induced host-changes that lead to increased susceptibility to bacterial pneumonia, review virulence strategies employed by the most prevalent secondary bacterial pneumonia species, and highlight recent findings of bacterial sensing and responding to the influenza infected environment.","PeriodicalId":13671,"journal":{"name":"Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":5.8,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42744400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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