Anissa Martins Bexiga, Ana Maria Portela, Stéphane Gaudry, Khalil Chaïbi
{"title":"When left feels right","authors":"Anissa Martins Bexiga, Ana Maria Portela, Stéphane Gaudry, Khalil Chaïbi","doi":"10.1007/s00134-024-07746-4","DOIUrl":"https://doi.org/10.1007/s00134-024-07746-4","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"9 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leveraging the power of routinely collected ICU data","authors":"Lada Lijović, Paul Elbers","doi":"10.1007/s00134-024-07745-5","DOIUrl":"https://doi.org/10.1007/s00134-024-07745-5","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"19 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Greet De Vlieger, Jay L. Koyner, Marlies Ostermann
{"title":"Can we use artificial intelligence to better treat acute kidney injury?","authors":"Greet De Vlieger, Jay L. Koyner, Marlies Ostermann","doi":"10.1007/s00134-024-07743-7","DOIUrl":"https://doi.org/10.1007/s00134-024-07743-7","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"37 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The role of artificial intelligence in life-sustaining treatment decisions: current state and future considerations","authors":"Bernhard Wernly, Bertrand Guidet, Michael Beil","doi":"10.1007/s00134-024-07738-4","DOIUrl":"https://doi.org/10.1007/s00134-024-07738-4","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"81 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma-Jane Spencer, Nicoleta J. Economou-Zavlanos, Michel E. van Genderen
{"title":"What if we do, but what if we don’t? The opportunity cost of artificial intelligence hesitancy in the intensive care unit","authors":"Emma-Jane Spencer, Nicoleta J. Economou-Zavlanos, Michel E. van Genderen","doi":"10.1007/s00134-024-07747-3","DOIUrl":"https://doi.org/10.1007/s00134-024-07747-3","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"9 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giulia Catozzi, Tommaso Pozzi, Domenico Nocera, Beatrice Donati, Stefano Giovanazzi, Valentina Ghidoni, Mauro Galizia, Rosanna D’Albo, Mattia Busana, Federica Romitti, Alessandro Gatta, Onnen Moerer, Konrad Meissner, Michael Quintel, Peter Herrmann, Davide Chiumello, Luigi Camporota, Luciano Gattinoni
{"title":"Rethinking ARDS classification: oxygenation impairment fails to predict VILI risk","authors":"Giulia Catozzi, Tommaso Pozzi, Domenico Nocera, Beatrice Donati, Stefano Giovanazzi, Valentina Ghidoni, Mauro Galizia, Rosanna D’Albo, Mattia Busana, Federica Romitti, Alessandro Gatta, Onnen Moerer, Konrad Meissner, Michael Quintel, Peter Herrmann, Davide Chiumello, Luigi Camporota, Luciano Gattinoni","doi":"10.1007/s00134-024-07712-0","DOIUrl":"https://doi.org/10.1007/s00134-024-07712-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>The selection and intensity of respiratory support for ARDS are guided by PaO<sub>2</sub>/FiO<sub>2</sub>. However, ventilator-induced lung injury (VILI) is linked to respiratory mechanics and ventilator settings. We explored whether the VILI risk is related to ARDS severity based on oxygenation.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>We analysed data on 228 ARDS subjects with PaO<sub>2</sub>/FiO<sub>2</sub> < 200 mmHg, categorized into three severity groups: one based on PaO<sub>2</sub>/FiO<sub>2</sub> ratio, and the others based on tertiles of predictors of VILI: mechanical power ratio (MPR) and driving pressure (DP). In each group of oxygenation-based ARDS severity and MPR and DP tertiles, we measured CT anatomy, gas exchange, respiratory mechanics, VILI prerequisites (lung elastance and lung gas volume), and VILI determinants (tidal volume, PEEP, airway pressures).</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>Predictors of VILI, such as MPR and DP, were similar across ARDS severity groups based on PaO<sub>2</sub>/FiO<sub>2</sub> ratio, while oxygenation remained comparable across different levels of VILI risk defined by MPR and DP. Oxygenation impairment was associated with increased lung weight, recruitability, and reduced well-inflated tissue. In contrast, MPR and DP tertiles affected variables associated with the baby lung size, such as lung gas volume and well-inflated tissue. Mechanical ventilation intensity increased progressively across MPR and DP tertiles, but remained similar across PaO<sub>2</sub>/FiO<sub>2</sub> severity groups.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>ARDS severity based on oxygenation impairment does not reflect the prerequisites and determinants of VILI. This should prompt a reconsideration of recommending respiratory support based on oxygenation impairment, rather than VILI determinants.</p>","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"1 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142805448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Misunderstanding buffering in critical illness.","authors":"S Magder","doi":"10.1007/s00134-024-07714-y","DOIUrl":"https://doi.org/10.1007/s00134-024-07714-y","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":27.1,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142800661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cassilia Dei, Capucine Belcadi, Jean Dellamonica, Denis Doyen
{"title":"Hemophagocytic lymphohistiocytosis complicating severe malaria: look for hemozoin","authors":"Cassilia Dei, Capucine Belcadi, Jean Dellamonica, Denis Doyen","doi":"10.1007/s00134-024-07716-w","DOIUrl":"https://doi.org/10.1007/s00134-024-07716-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"9 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142760069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How to manage sodium-glucose cotransporter-2 inhibitors in the critically ill patient?","authors":"Bruno Garcia, Marlies Ostermann, Matthieu Legrand","doi":"10.1007/s00134-024-07704-0","DOIUrl":"https://doi.org/10.1007/s00134-024-07704-0","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"13 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142758491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}