Intensive Care Medicine最新文献

{"title":"Beyond borders: reflections on a critical care fellowship between Ethiopia and Canada.","authors":"Finot Debebe Yayehyirad","doi":"10.1007/s00134-025-08123-5","DOIUrl":"https://doi.org/10.1007/s00134-025-08123-5","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"4 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145319231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of ventilator weaning in patients intubated for Guillain-Barré syndrome or myasthenia gravis: a nationwide multicenter study.","authors":"Arnaud W Thille,Constance Bayon,Marie Gauvrit,Clément Saccheri,Marie Labruyere,Gaetan Beduneau,Guilhem Wattecamps,Matthieu Henry,Eddine Bendiab,Benjamin Swinyard,Arnaud Gacouin,Adam Celier,Benjamin Foucou,Suzanne Champion,Anne-Fleur Haudebourg,Laurence Dangers,Olivier Plateker,Cedric Daubin,Lucie Fromont,Charlotte Guesdon,Emmanuel Vivier,Lev Volkov,Cyril Potier,Jeremy Bourenne,Charlotte Chiquet,Valentin Pointurier,Louis Chauvelot,Pierre Bailly,David Schnell,Nicholas Sedillot,Florian Reizine,Laurent Argaud,Faustine Reynaud,Juliette Pelle,Olivier Lesieur,Adrien Auvet,Guillaume Lacave,Marion Kernevez,Damien Contou,Guillaume Grillet,Arnaud Delahaye,Julio Badie,Jerome Devaquet,Hermine Chauvin,Alexandra Beurton,Emanuel Turbil,Jean-Philippe Rigaud,Stéphanie Ragot,Louis Chamblet,Rémi Coudroy,Sylvain Le Pape","doi":"10.1007/s00134-025-08159-7","DOIUrl":"https://doi.org/10.1007/s00134-025-08159-7","url":null,"abstract":"PURPOSESevere forms of Guillain-Barré syndrome (GBS) and myasthenia gravis (MG) may result in prolonged mechanical ventilation in ICUs. Data on weaning from mechanical ventilation are scarce, and our objective was to assess ventilator weaning characteristics in a large-scale multicenter study.METHODSMulticenter retrospective cohort study including all patients intubated for at least 48 h for GBS or MG over a 10-year period (from January 2014 to December 2023). The primary outcome was the proportion of patients having experienced prolonged weaning (at least 7 days).RESULTSSome 886 patients admitted to 47 ICUs in France were retained in the analysis, including 513 (58%) with GBS and 373 (42%) with MG. Patients with GBS were more likely to experience prolonged weaning than those with MG (64% vs. 35%, p < 0.001). An extubation attempt was performed in only 46% of patients with GBS and in 88% patients with MG (p < 0.001). Reintubation rates were 26% in patients with GBS and 29% in patients with MG (p = 0.440). Patients with GBS were more likely to undergo tracheostomy than those with MG (57% vs. 17%, p < 0.001). Patients with GBS required a longer duration of mechanical ventilation and ICU stay. Mortality rates were similar (9.4% for patients with GBS and 9.7% for patients with MG, p = 0.882).CONCLUSIONSPatients with GBS were more likely to experience prolonged weaning and to undergo tracheostomy than patients with MG. More than one-fourth of patients required reintubation after an extubation attempt. Despite prolonged duration of mechanical ventilation, mortality remained relatively low.","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"10 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145319246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Melatonin for ICU delirium prevention: Author's replies to the commentaries on the DEMEL trial.","authors":"Armand Mekontso Dessap,Etienne Audureau,Keyvan Razazi, ","doi":"10.1007/s00134-025-08145-z","DOIUrl":"https://doi.org/10.1007/s00134-025-08145-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"8 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145288265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the saline versus balanced debate: a neuro-systemic framework for fluid therapy in acute brain injury.","authors":"Bruno Zawadzki,Roberto Camargo Narciso,Rogério da Hora Passos","doi":"10.1007/s00134-025-08152-0","DOIUrl":"https://doi.org/10.1007/s00134-025-08152-0","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"83 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145288469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ten tips on non-therapeutic hypothermia","authors":"Nathan D. Nielsen, Thomas Spadoni, Marc Leone","doi":"10.1007/s00134-025-08158-8","DOIUrl":"https://doi.org/10.1007/s00134-025-08158-8","url":null,"abstract":"No Abstract","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"20 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145283522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transfusion targets after acute brain injury: the view of the trialists.","authors":"Fabio Silvio Taccone,Shane W English,Alexis F Turgeon","doi":"10.1007/s00134-025-08164-w","DOIUrl":"https://doi.org/10.1007/s00134-025-08164-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"3 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-intensive care syndrome is a potential consequence of critical care: can intensivists afford to look away?","authors":"Anne-Françoise Rousseau,Vincent Fraipont,Jean-Charles Preiser","doi":"10.1007/s00134-025-08156-w","DOIUrl":"https://doi.org/10.1007/s00134-025-08156-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"37 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalizing beta-lactams therapy in critical patients undergoing RRT: moving a further step forward?","authors":"Tommaso Tonetti,Milo Gatti,Federico Pea","doi":"10.1007/s00134-025-08165-9","DOIUrl":"https://doi.org/10.1007/s00134-025-08165-9","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"209 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publisher Correction: Monocyte HLA-DR expression in septic shock patients: insights from a 20-year real-world cohort of 1023 cases.","authors":"Guillaume Monneret, Thomas Lafon, Morgane Gossez, Bruno Evrard, Maxime Bodinier, Thomas Rimmelé, Laurent Argaud, Martin Cour, Arnaud Friggeri, Alain Lepape, Bernard Allaouchiche, Anne-Claire Lukaszewicz, Fabienne Venet","doi":"10.1007/s00134-025-08161-z","DOIUrl":"https://doi.org/10.1007/s00134-025-08161-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary tract fungus balls in an immunocompromised patient with persistent candida albicans fungemia.","authors":"Antoine Hérault,Lucie Vangheluwe,Kévin Alexandre,Dominique Vodovar","doi":"10.1007/s00134-025-08129-z","DOIUrl":"https://doi.org/10.1007/s00134-025-08129-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"13 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}