Intensive Care Medicine最新文献

{"title":"Underdamping: An elephant in the room?","authors":"Stefano Romagnoli, Bernd Saugel, Gabriele Baldini, Frederic Michard, Zaccaria Ricci","doi":"10.1007/s00134-026-08463-w","DOIUrl":"https://doi.org/10.1007/s00134-026-08463-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative ARDS: beyond definitions toward etiology-driven care.","authors":"Stefano Romagnoli, Lorenzo Ball, Samir Jaber","doi":"10.1007/s00134-026-08465-8","DOIUrl":"https://doi.org/10.1007/s00134-026-08465-8","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predicted body weight equation overestimates lung sizes of female, critically ill patients: an analysis of randomized, controlled trials and real-world clinical data.","authors":"Dario von Wedel, Simone Redaelli, Maxime Fosset, Joris Pensier, Denys Shay, Elena Ahrens, Luca J Wachtendorf, Eva-Lotte Seibold, Aiman Suleiman, Patricia W Wu, Seth J Berkowitz, Tayran Milá, Felix Balzer, Eduardo V Costa, Boris Jung, Elias N Baedorf Kassis, Marcelo B Amato, Daniel Talmor, Maximilian S Schaefer","doi":"10.1007/s00134-026-08442-1","DOIUrl":"https://doi.org/10.1007/s00134-026-08442-1","url":null,"abstract":"<p><strong>Purpose: </strong>Low tidal volume (Vt) ventilation is the standard of care among critically ill patients. Guidelines recommend scaling Vt to the predicted body weight (PBW) to avoid ventilator-induced lung injury (VILI). Concerns exist that the PBW overestimates lung volumes of critically ill females. We investigated whether this applies to clinically relevant measures of lung volume, whether PBW-guided mechanical ventilation yields comparable risk of lung stress among male and female patients, and whether this affects mortality.</p><p><strong>Methods: </strong>Mechanically ventilated, critically ill patients from ten randomized trials and two real-world retrospective clinical datasets were analyzed. Risk of high driving pressures (≥ 15 cmH₂O) at comparable Vt/kg PBW as well as measures of anatomical and functional lung sizes, including computed tomography-measured lung volumes at the same PBW were compared between female and male patients.</p><p><strong>Results: </strong>Among 30,516 patients (39.4% female), ventilation with comparable tidal volumes standardized to PBW (ml/kg PBW) was associated with 4.2% (95% CI 3.2-5.3; aOR 1.26, 95% CI 1.19-1.33; p < 0.001) higher absolute risk of high driving pressures among females, mediating 8.4% of excess 28-day mortality (p < 0.001). At the same PBW, female patients had lower anatomical and aerated lung volumes (- 343 ml, 95% CI - 449 to - 237, p < 0.001; and - 188, 95% CI - 282 to - 94, p < 0.001, respectively) than males.</p><p><strong>Conclusions: </strong>The widely used PBW equation overestimates lung volumes in female critically ill patients, resulting in excess risk of injurious driving pressures among females, mediating higher mortality. Personalized mechanical ventilation by using driving pressure-guided strategies might mitigate these disparities.</p>","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypereosinophilic syndrome and cerebral watershed infarction.","authors":"Jingjing Huang, Yiheng Cheng, Chunyong Chen","doi":"10.1007/s00134-026-08452-z","DOIUrl":"https://doi.org/10.1007/s00134-026-08452-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting septic cardiomyopathy: the missing role of systolic function in interpreting diastolic dysfunction and outcomes.","authors":"Luis A Bustamante-Cristancho","doi":"10.1007/s00134-026-08458-7","DOIUrl":"https://doi.org/10.1007/s00134-026-08458-7","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Venous air embolism following blast injury: not always imaging the worst.","authors":"Gaël de Rocquigny, Arnaud de Rousiers, Jean-Clément Riff, Amaury Perchoc","doi":"10.1007/s00134-026-08417-2","DOIUrl":"https://doi.org/10.1007/s00134-026-08417-2","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Publisher Correction: Surviving Sepsis Campaign: international guidelines for management of sepsis and septic shock 2026.","authors":"Hallie C Prescott, Massimo Antonelli, Waleed Alhazzani, Morten Hylander Møller, Fayez Alshamsi, Luciano C P Azevedo, Emilie Belley-Cote, Jan De Waele, Lennie Derde, Joanna C Dionne, Laura Evans, Hayley B Gershengorn, Carol L Hodgson, Kimia Honarmand, Jozef Kesecioglu, Lauralyn McIntyre, Mervyn Mer, Mark E Nunnally, Simon J W Oczkowski, Bram Rochwerg, Olurotimi Olaolu Akinola, Kwame A Akuamoah-Boateng, Laura Alberto, Derek C Angus, Yaseen M Arabi, Elie Azoulay, Maurizio Cecconi, Pauline F Convocar, Gennaro De Pascale, Kent Doi, Bin Du, Moritoki Egi, Marie-Carmelle Elie-Turenne, Ricard Ferrer, Alison Fox-Robichaud, Craig French, Yonathan Freund, Michelle Ng Gong, Caleb P Hale, Naomi E Hammond, Madiha Hashmi, Leo Heunks, Theodore J Iwashyna, Shevin T Jacob, Michael Klompas, Arthur Kwizera, Murdoch Leeies, Joanna D Lejnieks, Mitchell M Levy, Flavia R Machado, Marcelo O Maia, Henry Masur, Ryan C Maves, Steven McGloughlin, Joanne McPeake, Nicholas M Mohr, Sheila Nainan Myatra, Marlies Ostermann, Sandra L Peake, Mathias W Pletz, Jason A Roberts, Regis G Rosa, Robert G Sawyer, Christa A Schorr, Steven Q Simpson, Li Weng, W Joost Wiersinga, Andrew Rhodes, Craig M Coopersmith","doi":"10.1007/s00134-026-08410-9","DOIUrl":"https://doi.org/10.1007/s00134-026-08410-9","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stroke or mimic? A clinical fork in the road.","authors":"Gwendal Coste, Clément Rombi, Ghazi Hmeydia, Bertrand Hermann","doi":"10.1007/s00134-026-08456-9","DOIUrl":"https://doi.org/10.1007/s00134-026-08456-9","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bridging the gap: pragmatic neuromonitoring and management of traumatic brain injury in resource-limited settings.","authors":"Andres M Rubiano, Laura M Loaiza-Cardona, Walter Videtta","doi":"10.1007/s00134-026-08455-w","DOIUrl":"https://doi.org/10.1007/s00134-026-08455-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking patient-ventilator asynchronies: toward a mechanism-based framework.","authors":"Mohamed Boussarsar","doi":"10.1007/s00134-026-08447-w","DOIUrl":"https://doi.org/10.1007/s00134-026-08447-w","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":21.2,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147814632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}