Chiara Robba, Edoardo Picetti, Sebastián Vásquez-García, Yasser B. Abulhasan, Amelia Ain, Amos O. Adeleye, Marcel Aries, Sérgio Brasil, Rafael Badenes, Alessandro Bertuccio, Pierre Bouzat, Luis Bustamante, Lorenzo Calabro’, Hassane Njimi, Danilo Cardim, Giuseppe Citerio, Marek Czosnyka, Thomas Geeraerts, Daniel A. Godoy, Mohammad I. Hirzallah, Bhagavatula Indira Devi, Manuel Jibaja, Piergiorgio Lochner, Julio C. Mijangos Méndez, Geert Meyfroidt, Thangaraj Munusamy, Juan Pinedo Portilla, Hemanshu Prabhakar, Frank Rasulo, Diana M. Sánchez Parra, Aarti Sarwal, Gentle S. Shrestha, Dhaval P. Shukla, Gene Sung, Abenezer Tirsit, Franly Vásquez, Walter Videtta, Yu Lin Wang, Wellingson S. Paiva, Fabio Silvio Taccone, Andres M. Rubiano
{"title":"The Brussels consensus for non-invasive ICP monitoring when invasive systems are not available in the care of TBI patients (the B-ICONIC consensus, recommendations, and management algorithm)","authors":"Chiara Robba, Edoardo Picetti, Sebastián Vásquez-García, Yasser B. Abulhasan, Amelia Ain, Amos O. Adeleye, Marcel Aries, Sérgio Brasil, Rafael Badenes, Alessandro Bertuccio, Pierre Bouzat, Luis Bustamante, Lorenzo Calabro’, Hassane Njimi, Danilo Cardim, Giuseppe Citerio, Marek Czosnyka, Thomas Geeraerts, Daniel A. Godoy, Mohammad I. Hirzallah, Bhagavatula Indira Devi, Manuel Jibaja, Piergiorgio Lochner, Julio C. Mijangos Méndez, Geert Meyfroidt, Thangaraj Munusamy, Juan Pinedo Portilla, Hemanshu Prabhakar, Frank Rasulo, Diana M. Sánchez Parra, Aarti Sarwal, Gentle S. Shrestha, Dhaval P. Shukla, Gene Sung, Abenezer Tirsit, Franly Vásquez, Walter Videtta, Yu Lin Wang, Wellingson S. Paiva, Fabio Silvio Taccone, Andres M. Rubiano","doi":"10.1007/s00134-024-07756-2","DOIUrl":"https://doi.org/10.1007/s00134-024-07756-2","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Background</h3><p>Invasive systems are commonly used for monitoring intracranial pressure (ICP) in traumatic brain injury (TBI) and are considered the gold standard. The availability of invasive ICP monitoring is heterogeneous, and in low- and middle-income settings, these systems are not routinely employed due to high cost or limited accessibility. The aim of this consensus was to develop recommendations to guide monitoring and ICP-driven therapies in TBI using non-invasive ICP (nICP) systems.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>A panel of 41 experts, that regularly use nICP systems for guiding TBI care, was established. Three scoping and four systematic reviews with meta-analysis were performed summarizing the current global-literature evidence. A modified Delphi method was applied for the development of recommendations. An in-person meeting with group discussions and voting was conducted. Strong recommendations were defined for an agreement of at least 85%. Weak recommendations were defined for an agreement of 75–85%.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>A total of 34 recommendations were provided (32 Strong, 2 Weak) divided into three domains: general consideration for nICP use, management of ICP using nICP methods and thresholds of nICP tools for escalating/de-escalating treatment. We developed four clinical algorithms for escalating treatment and heatmaps for de-escalating treatment.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>Using a mixed-method approach involving literature review and an in-person consensus by experts, a set of recommendations designed to assist clinicians managing TBI patients using nICP systems plus clinical assessment, in the presence or absence of brain imaging, were built. Further clinical studies are required to validate the potential use of these recommendations in the daily clinical practice.</p>","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"25 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143020365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luigi Camporota, Antonio Pesenti, Giuseppe Citerio
{"title":"Luciano Gattinoni: a visionary that transformed Intensive Care Medicine","authors":"Luigi Camporota, Antonio Pesenti, Giuseppe Citerio","doi":"10.1007/s00134-024-07781-1","DOIUrl":"https://doi.org/10.1007/s00134-024-07781-1","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"6 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How AI can help in error detection and prevention in the ICU?","authors":"Anne Rike Flint, Stefan J. Schaller, Felix Balzer","doi":"10.1007/s00134-024-07775-z","DOIUrl":"https://doi.org/10.1007/s00134-024-07775-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"137 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amanda Y. Leong, Stefan Edginton, Laurie A. Lee, Natalia Jaworska, Lisa Burry, Kirsten M. Fiest, Christopher J. Doig, Daniel J. Niven
{"title":"The association between pain, analgesia, and delirium among critically ill adults: a systematic review and meta-analysis","authors":"Amanda Y. Leong, Stefan Edginton, Laurie A. Lee, Natalia Jaworska, Lisa Burry, Kirsten M. Fiest, Christopher J. Doig, Daniel J. Niven","doi":"10.1007/s00134-025-07784-6","DOIUrl":"https://doi.org/10.1007/s00134-025-07784-6","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose</h3><p>We performed a systematic review with meta-analysis examining the relationship between pain or pain medications and delirium occurence, duration, and severity.</p><h3 data-test=\"abstract-sub-heading\">Methods</h3><p>We searched MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials from inception to May 15, 2023. We included randomised or observational studies among critically ill adults, that reported data on pain or exposure to analgesics, and reported delirium presence, duration, or severity with no language or region restrictions. PROSPERO ID: CRD42022367715. Two authors independently screened records and extracted data. Risk of bias was evaluated using Risk of Bias 2 or the Risk of Bias In Non-randomized Studies of Interventions. We pooled data using the Hartung-Knapp Sidik-Jonkmann random effects model. PRISMA was followed.</p><h3 data-test=\"abstract-sub-heading\">Results</h3><p>From 8,054 citations, 90 studies (119,230 patients) published between 2001 and 2023 were included in the systematic review. 41 studies were included in the primary meta-analysis examining prevalent delirium: seven studies evaluated pain; 12 studies evaluated fentanyl; and five studies evaluated morphine. There was a trend to association between pain and delirium occurrence (OR 2.49, 95% CI 0.98–6.30), and a significant association between pain and incident delirium (OR 3.70, 95% CI 1.73–7.93). Fentanyl (OR 2.49, 95% CI 1.45–4.27) and morphine (OR 2.13, 95% CI 1.21–3.75) were associated with delirium occurrence. Risk of bias was critical for many studies.</p><h3 data-test=\"abstract-sub-heading\">Conclusions</h3><p>We observed an association between pain and incident delirium among critically ill adults. Exposure to morphine or fentanyl (but no other pain medications) was associated with increased risk of delirium occurrence.</p>","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"32 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Romain Sonneville, Etienne de Montmollin, Damien Contou, Ricard Ferrer, Mohan Gurjar, Kada Klouche, Benjamine Sarton, Sophie Demeret, Pierre Bailly, Daniel da Silva, Etienne Escudier, Loic Le Guennec, Russel Chabanne, Laurent Argaud, Omar Ben Hadj Salem, Martial Thyrault, Aurélien Frerou, Guillaume Louis, Gennaro De Pascale, Janneke Horn, Raimund Helbok, Guillaume Geri, Fabrice Bruneel, Ignacio Martin-Loeches, Fabio Silvio Taccone, Jan J De Waele, Stéphane Ruckly, Quentin Staiquly, Giuseppe Citerio, Jean-François Timsit
{"title":"Correction: Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study.","authors":"Romain Sonneville, Etienne de Montmollin, Damien Contou, Ricard Ferrer, Mohan Gurjar, Kada Klouche, Benjamine Sarton, Sophie Demeret, Pierre Bailly, Daniel da Silva, Etienne Escudier, Loic Le Guennec, Russel Chabanne, Laurent Argaud, Omar Ben Hadj Salem, Martial Thyrault, Aurélien Frerou, Guillaume Louis, Gennaro De Pascale, Janneke Horn, Raimund Helbok, Guillaume Geri, Fabrice Bruneel, Ignacio Martin-Loeches, Fabio Silvio Taccone, Jan J De Waele, Stéphane Ruckly, Quentin Staiquly, Giuseppe Citerio, Jean-François Timsit","doi":"10.1007/s00134-025-07792-6","DOIUrl":"https://doi.org/10.1007/s00134-025-07792-6","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":" ","pages":""},"PeriodicalIF":27.1,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Aabdi, Hicham Nassik, Youssef Motiaa, Brahim Boukatta, Hicham Sbai
{"title":"End-of-life practices in intensive care units in Morocco: challenges and unmet educational needs","authors":"Mohammed Aabdi, Hicham Nassik, Youssef Motiaa, Brahim Boukatta, Hicham Sbai","doi":"10.1007/s00134-025-07800-9","DOIUrl":"https://doi.org/10.1007/s00134-025-07800-9","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"22 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new chapter in intensive care medicine","authors":"Samir Jaber","doi":"10.1007/s00134-025-07799-z","DOIUrl":"https://doi.org/10.1007/s00134-025-07799-z","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"15 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yoshihiro Nagai, Shigehiko Uchino, Ken Tonai, Shinshu Katayama
{"title":"“Tracheal ballooning” during positive-pressure ventilation in a patient with status asthmaticus and acquired tracheomegaly","authors":"Yoshihiro Nagai, Shigehiko Uchino, Ken Tonai, Shinshu Katayama","doi":"10.1007/s00134-025-07798-0","DOIUrl":"https://doi.org/10.1007/s00134-025-07798-0","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"10 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142992118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katrina Augustin,Zachary M Shinar,Dinis Dos Reis Miranda
{"title":"Correspondence by Augustin et al. regarding the article \"Conservative or liberal oxygen targets in patients on venoarterial extracorporeal membrane oxygenation\".","authors":"Katrina Augustin,Zachary M Shinar,Dinis Dos Reis Miranda","doi":"10.1007/s00134-025-07791-7","DOIUrl":"https://doi.org/10.1007/s00134-025-07791-7","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"13 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142991757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andres Giglio Jiménez, Weimar Tovar, Cesar Pedreros, Andrés Ferre
{"title":"Should we move beyond the concept of fluid responsiveness?","authors":"Andres Giglio Jiménez, Weimar Tovar, Cesar Pedreros, Andrés Ferre","doi":"10.1007/s00134-025-07787-3","DOIUrl":"https://doi.org/10.1007/s00134-025-07787-3","url":null,"abstract":"","PeriodicalId":13665,"journal":{"name":"Intensive Care Medicine","volume":"27 1","pages":""},"PeriodicalIF":38.9,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142989863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}