Internal and Emergency Medicine最新文献

{"title":"Ultrasound assessment of constipation: do not put the cart before the horse.","authors":"Gabrio Bassotti","doi":"10.1007/s11739-025-04120-0","DOIUrl":"https://doi.org/10.1007/s11739-025-04120-0","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The dexterity of the monkey and the blurred words.","authors":"Carlo Bellini","doi":"10.1007/s11739-025-04126-8","DOIUrl":"https://doi.org/10.1007/s11739-025-04126-8","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided nerve blocks: expert opinion statement on patient monitoring in the emergency department setting.","authors":"Lachlan Driver, Leland Perice, Joseph R Brown, Arun Nagdev, Andrew Goldsmith","doi":"10.1007/s11739-025-04122-y","DOIUrl":"https://doi.org/10.1007/s11739-025-04122-y","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond hospitalizations: uncovering underdiagnosed hepatocellular carcinoma during COVID-19.","authors":"Qi Xu, Yuwan Gao","doi":"10.1007/s11739-025-04119-7","DOIUrl":"https://doi.org/10.1007/s11739-025-04119-7","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atypical adult-onset hand, foot, and mouth disease.","authors":"Takumi Nomura, Takeshi Takahashi, Kento Ko, Toru Kawai, Arata Horii","doi":"10.1007/s11739-025-04125-9","DOIUrl":"https://doi.org/10.1007/s11739-025-04125-9","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GLP-1 and GIP agonists in diabetes and obesity and the rise of dyspepsia.","authors":"Maria Masulli, Jan Tack, Giuseppe Esposito, Giovanni Sarnelli","doi":"10.1007/s11739-025-04117-9","DOIUrl":"https://doi.org/10.1007/s11739-025-04117-9","url":null,"abstract":"<p><p>Glucagon-like peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) agonists, such as tirzepatide, have transformed the management of type 2 diabetes and obesity through durable glycemic control, weight reduction, and cardiovascular protection. However, their widespread use has revealed a high incidence of gastrointestinal adverse events, particularly dyspepsia and gastroparesis-like symptoms. While most effects are transient, a significant subset of patients develop persistent intolerance, often leading to misdiagnosis, unnecessary investigations, or premature treatment discontinuation. Current therapeutic options remain limited, with guidelines offering little direction for managing symptoms, in this subset of dyspeptic patients. This growing clinical challenge highlights the urgent need for structured strategies, including risk stratification, tailored dose titration, and multidisciplinary care, to balance metabolic efficacy with gastrointestinal tolerability.</p>","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145102825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of point-of-care ultrasound for rapid assessment of sarcopenia risk in inpatient frail older people: a cross-sectional study.","authors":"Laisa Socorro Briongos Figuero, Miriam Gabella Martín, Fernando Gil Díez, Graciela López Muñiz, Julia Pérez Nieto, Victoria Olivet de la Fuente, Jesús Franco Rodríguez, Ainhoa Martín Galán, Luis Corral Gudino, José Pablo Miramontes González","doi":"10.1007/s11739-025-04109-9","DOIUrl":"https://doi.org/10.1007/s11739-025-04109-9","url":null,"abstract":"<p><p>Bedside ultrasound (POCUS) has emerged as a non-invasive, reliable, and practical tool for evaluating muscle mass since sarcopenia poses a significant threat to multimorbidity older people. The aim of the study was to evaluate sarcopenia risk among frail older inpatients using POCUS on rectus femoris muscle (RFM) and explore the relationship between these condition and clinical outcomes. An observational study was conducted including inpatients over 80 years old, admitted due to dyspnea during the winter-spring of 2024. POCUS was done with a 5-MHz convex probe device in RFM (middle point). We determined sarcopenia risk (SARC-F tool), FRAIL scale, handgrip strength, calf circumference (CC), body mass index (BMI), Charlson index (CI), nutritional status (MNA-SF), serum albumin, dependency degree (Barthel index), and quality of life with EQ5D5L questionnaire. Data were analyzed using SPSS v.25.0. The study was approved by the ethics committee. Ultrasound sarcopenia was found in 33% of all participants. POCUS RFM muscle thickness showed moderate positive significant correlation with BMI (r = 0.32; p = 0.01), arm circumference (r = 0.38; p = 0.003), CC (r = 0.5; p < 0.001), and handgrip strength (r = 0.25; p = 0.04). Otherwise, POCUS RFM muscle thickness showed moderate or weak negative significant correlation with age (r = - 0.22; p = 0.05), CI (r = - 0.24; p = 0.01), dependence Barthel index (r = - 0.12; p = 0.05), nutritional status (r = - 0.18; p = 0.01), and frailty scale (r = - 0.19; p = 0.05). Integration of POCUS in comprehensive assessment of quality of life, sarcopenia, nutritional status, and frailty in the oldest old represents a promising approach. This study provides a foundation for implementation of routine sarcopenia screening and intervention programs in the clinical management of multimorbidity in older patients.</p>","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145086025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term left ventricular thrombosis resolution in patients receiving vitamin K antagonists: reply to comment.","authors":"Emanuele Valeriani, Arianna Pannunzio, Daniele Pastori, Walter Ageno, Cecilia Becattini, Pasquale Pignatelli","doi":"10.1007/s11739-025-04111-1","DOIUrl":"https://doi.org/10.1007/s11739-025-04111-1","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145075349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary: enhancing CAP severity prediction in elderly patients through dynamic cytokine monitoring.","authors":"Shunyu Ning, Zhiting Liu, Yixin Ma","doi":"10.1007/s11739-025-04081-4","DOIUrl":"https://doi.org/10.1007/s11739-025-04081-4","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards a sustainable pricing of pharmaceutical goods: reply.","authors":"Rachele Ciccocioppo, Natividad Cuende","doi":"10.1007/s11739-025-04010-5","DOIUrl":"https://doi.org/10.1007/s11739-025-04010-5","url":null,"abstract":"","PeriodicalId":13662,"journal":{"name":"Internal and Emergency Medicine","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}