Integrative medicine最新文献_第8页

Vulvar Lichen Sclerosus: A Literature Review with Consideration of Integrative Therapies. 外阴硬化苔藓：综合治疗的文献综述。

Integrative medicine Pub Date : 2025-02-01

Kathleen Jade

{"title":"Vulvar Lichen Sclerosus: A Literature Review with Consideration of Integrative Therapies.","authors":"Kathleen Jade","doi":"","DOIUrl":"","url":null,"abstract":"Vulvar lichen sclerosus (VLS) is a chronic inflammatory skin condition characterized by vulvar pruritus, pain, dyspareunia, and architectural changes, including significant and permanent scarring and deformity of the vulva if left untreated. Untreated VLS significantly increases the risk of invasive squamous cell carcinoma, even in asymptomatic patients. However, there is an overall paucity of preclinical and clinical research on VLS. Although the disease is becoming more commonly recognized, it is often under- or misdiagnosed and its prevalence is likely underestimated. While the exact underlying etiology is still unknown, VLS is most likely an autoimmune disorder within the background of genetic predisposition and environmental triggers. The skin and gut microbiomes also appear to be involved. The first line treatment for VLS, ultrapotent topical corticosteroids, helps relieve symptoms and reduce the risk of architectural changes and vulvar cancer. The second-line medications and treatments with more limited evidence of efficacy include topical calcineurin inhibitors, topical hormones, platelet-rich plasma, and fractional CO2 laser therapy. Surgical intervention may also be required. Additionally, some VLS patients and practitioners report improvements with diet and lifestyle changes, nutritional supplements, low-dose naltrexone, botanical medicines, and other integrative treatments, although clinical research on these integrative therapies for VLS is generally lacking. This review aims to describe VLS in adult women, summarize the recently published literature, and provide a clinical overview that includes evidence-based integrative therapies.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"24 1","pages":"16-25"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revealing the in-office study findings of Daiwa Brain Health vs. Prevagen. 揭示大和脑健康与Prevagen的办公室研究结果。

Integrative medicine Pub Date : 2025-02-01

Sheldon Baker

引用次数: 0

The Road to Cancer Recovery for Melanie Cole and Caitlin Whyte. 梅勒妮·科尔和凯特琳·怀特的《癌症康复之路》。

Integrative medicine Pub Date : 2025-02-01

Sheldon Baker

引用次数: 0

Impact of Short-Term Integrated Yoga Therapy Intervention on Systemic Inflammatory Markers and Quality of Life in Rheumatoid Arthritis Patients: A Randomized Controlled Trial. 短期综合瑜伽治疗干预对类风湿关节炎患者全身炎症标志物和生活质量的影响：一项随机对照试验。

Integrative medicine Pub Date : 2025-02-01

Geetha B Shetty, Prashanth Shetty, Balakrishna Shetty, H L Nanjeshgowda

{"title":"Impact of Short-Term Integrated Yoga Therapy Intervention on Systemic Inflammatory Markers and Quality of Life in Rheumatoid Arthritis Patients: A Randomized Controlled Trial.","authors":"Geetha B Shetty, Prashanth Shetty, Balakrishna Shetty, H L Nanjeshgowda","doi":"","DOIUrl":"","url":null,"abstract":"Background: Rheumatoid arthritis (RA) is an autoimmune disease with prolonged dysregulation of pro- and anti-inflammatory immune pathways resulting in chronic inflammation, which alters the functional status and quality of life. The present study aimed to assess the short-term effect of yoga therapy on systemic inflammatory markers and quality of life among RA patients.Methods: The study included one hundred RA patients aged 18-60 years and randomized into yoga (n = 50) and control (n = 50) groups. A structured yoga therapy was given for 12 weeks along with their regular disease-modifying antirheumatic medications (DMARDs). During the study period, all the participants were allowed to continue their daily lifestyle and diet.Results: After 12 weeks of intervention, the yoga group reported a significant decrease in interleukin-6 (IL 6) (P < .001), C-reactive protein (CRP) (P < .01), rheumatoid factor (RA factor) (P = .02), and erythrocyte sedimentation rate (ESR) (P = .05), compared to the control group. Furthermore, compared to the control group, yoga participants showed significant improvement in functional status and disease activity, which included the assessment of DAS-28 (to assess the disease activity) (P < .001), patient global assessment (P < .001), and reduced Visual Analogue Scale (VAS) score (pain intensity assessment) (P < .01). The secondary outcome was the quality of life (SF-36 questionnaire), which showed significant improvement post-intervention (P = .05).Conclusion: The present study has demonstrated that short-term yoga therapy could lower systemic inflammatory markers by maintaining immune homeostasis to improve the functional status and quality of life in RA patients.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"24 1","pages":"10-15"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11778323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoughts on Establishing a New Standard for Assessing Toxic Load in the General Population. 建立普通人群中毒性负荷评估新标准的思考。

Integrative medicine Pub Date : 2025-02-01

Joseph Pizzorno

引用次数: 0

An Interview with Joseph Pizzorno, ND, Talking About the Current Health Status in the United States, Part 3. 采访约瑟夫·皮佐诺，ND，谈论当前的健康状况在美国，第3部分。

Integrative medicine Pub Date : 2024-12-01

Sheldon Baker

引用次数: 0

Investigating GLP-1 Injections: Potential Mitochondrial Dysfunction in Non-Diabetic Patients Presenting with Migraines and Hypoglycemia: A Case Report. 研究GLP-1注射：出现偏头痛和低血糖的非糖尿病患者的潜在线粒体功能障碍：一例报告。

Integrative medicine Pub Date : 2024-12-01

Jana Jamail, Rachel Knowles, Leslie Fuller

{"title":"Investigating GLP-1 Injections: Potential Mitochondrial Dysfunction in Non-Diabetic Patients Presenting with Migraines and Hypoglycemia: A Case Report.","authors":"Jana Jamail, Rachel Knowles, Leslie Fuller","doi":"","DOIUrl":"","url":null,"abstract":"Introduction: GLP-1 medications are widely used for weight loss in patients with and without type 2 diabetes. However, limited research exists on their effects in non-diabetic patients, particularly concerning mitochondrial function. This case report investigates the potential of altered mitochondrial dysfunction as a cause of side effects of GLP-1 medications in patients without type 2 diabetes.Case presentation: The patient, a 43-year-old female with a BMI of 32, presented with hypoglycemia and persistent migraines with auras after Ozempic and Mounjaro injections.Outcomes: The patient changed her diet to include 90 grams of protein and frequent small meals throughout the day. She took CoQ10, D-ribose, vitamin B complex, and acetyl-l-carnitine, to address the migraines, and this also improved the mitochondrial function. The patient reported balanced blood sugar after changing her diet; her migraines improved and did not return after taking supplementation.Conclusion: This case report emphasizes the need for awareness and monitoring of potential mitochondrial side effects from GLP-1 injections in patients without type 2 diabetes. Nutritional and supplemental interventions effectively managed the patient's symptoms and emphasized the need for tailored interventions in patients using GLP-1 medications. Further research is needed to understand how GLP-1 injections impact mitochondrial function.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 6","pages":"21-25"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737221/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Neuroprotective Benefits Of Plant-Cell-Cultivated Saffron. 植物细胞培养的藏红花的神经保护作用。

Integrative medicine Pub Date : 2024-12-01

Sheldon Baker

引用次数: 0

Invisible Waves, Visible Consequences: Environmental Radiation's Role in Human Fertility. 看不见的波，可见的后果：环境辐射在人类生育中的作用。

Integrative medicine Pub Date : 2024-12-01

David K Simson, Apoorv Vashistha, Jaskaran Singh Sethi

{"title":"Invisible Waves, Visible Consequences: Environmental Radiation's Role in Human Fertility.","authors":"David K Simson, Apoorv Vashistha, Jaskaran Singh Sethi","doi":"","DOIUrl":"","url":null,"abstract":"Environmental radiation is one of the key causes of the increased prevalence of infertility among couples. This type of radiation can be ionizing or non-ionizing. While ionizing radiation is known to cause sterility in both males and females, the role of low-energy non-ionizing radiation is still debated. This article will discuss the various types of environmental radiation and its consequences on male and female fertility. Recent studies suggest that continuous exposure to low-energy, non-ionizing radiation might also result in infertility. The sources of this type of radiation are generally man-made, including mobile phones, television broadcasts, radio, radars, etc. The ever-increasing use of these devices in our daily lives has introduced a new type of pollution called electropollution. The mechanisms of action by which electropollution causes infertility are still being investigated. In males, prolonged exposure to this type of radiation might negatively impact sperm parameters, such as count, motility, morphology, and viability. The evidence for female infertility caused by non-ionizing radiation is still evolving.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 6","pages":"10-13"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11737223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dr. Karen Toubi, Board Certified Obstetrician and Gynecologist: Comprehensive Gynecology. Karen Toubi博士，董事会认证的妇产科医生：综合妇科。

Integrative medicine Pub Date : 2024-12-01

Sheldon Baker

引用次数: 0