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Conversations with Tim Eaton, Founder and Chief Executive Officer, NutraMedix. 与 NutraMedix 创始人兼首席执行官 Tim Eaton 的对话。
Integrative medicine Pub Date : 2023-11-01
Sheldon Baker
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引用次数: 0
Personalized Nutrition and Lifestyle Interventions in Systemic Lupus Erythematosus: A Case Report. 个体化营养和生活方式干预治疗系统性红斑狼疮1例。
Integrative medicine Pub Date : 2023-01-01 DOI: 10.2139/ssrn.3743841
Jan Kielmann, Leandro Pucci, Aikaterini Xydis
{"title":"Personalized Nutrition and Lifestyle Interventions in Systemic Lupus Erythematosus: A Case Report.","authors":"Jan Kielmann, Leandro Pucci, Aikaterini Xydis","doi":"10.2139/ssrn.3743841","DOIUrl":"https://doi.org/10.2139/ssrn.3743841","url":null,"abstract":"Background\u0000A 63-year-old male with a 4-year history of systemic lupus erythematosus (SLE) safely and successfully integrated personalized nutrition and lifestyle modifications to improve the symptomatic outcome of his illness.\u0000\u0000\u0000Case/Intervention\u0000The client presented to our nutritional practice with fatigue, acid reflux, joint pain, brain fog and skin rashes. During the nutritional intervention, he safely used a variety of nutritional interventions and supplementation, including dietary improvements, omega-3 fish oils, N-acetyl cysteine, prebiotics and intermittent fasting, along with stress reduction techniques. His symptoms decreased significantly, or disappeared, over 4 years of using these interventions.\u0000\u0000\u0000Conclusion\u0000This case demonstrates the safety and potential benefits of personalized nutrition, stress reduction techniques and targeted supplementation in helping to decrease symptoms of SLE. Our client's energy levels and overall performance improved, skin rashes and acid reflux resolved, joint pain and stiffness decreased and brain fog gradually lessened over the 4 years he was in our care.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"65 1","pages":"22-27"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91004987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Subclinical Hypercortisolism: An Important, Unrecognized Dysfunction. 亚临床高皮质醇症:一个重要的，未被认识的功能障碍。
Integrative medicine Pub Date : 2022-07-01
Lara Pizzorno, Joseph Pizzorno
{"title":"Subclinical Hypercortisolism: An Important, Unrecognized Dysfunction.","authors":"Lara Pizzorno,&nbsp;Joseph Pizzorno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>While Cushing syndrome is rare, but well-recognized, subclinical hypercortisolism (defined as excessive cortisol secretion without the classic manifestations of Cushing syndrome) is significantly more common. Subclinical hypercortisolism contributes to several chronic diseases, such as diabetes, osteoporosis, sarcopenia and hypertension. The incidence increases with age and correlates with body load of environmental toxins such as bisphenol A (BPA). This editorial discusses prevalence, contribution to disease, causes, diagnosis, and intervention.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"8-15"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380834/pdf/imcj-21-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40718822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conversation with James Greenblatt, MD-Integrative Medicine for Mental Health Conference. 对话詹姆斯格林布拉特，医学博士，心理健康会议的综合医学。
Integrative medicine Pub Date : 2021-08-01
Dick Benson
{"title":"Conversation with James Greenblatt, MD-Integrative Medicine for Mental Health Conference.","authors":"Dick Benson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"46-48"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483256/pdf/imcj-20-46.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ahiflower Oil-The Rising GLA Alternative to Evening Primrose for Women & Vegans. Ahiflower油-为女性和素食者提供月见草的GLA替代品。
Integrative medicine Pub Date : 2021-08-01
Andrew Myers, Greg Cumberford
{"title":"Ahiflower Oil-The Rising GLA Alternative to Evening Primrose for Women & Vegans.","authors":"Andrew Myers,&nbsp;Greg Cumberford","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"30-33"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483257/pdf/imcj-20-30.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Instability of the Lipid-Soluble Antioxidant Ubiquinol: Part 1-Lab Studies. 脂溶性抗氧化剂泛醇的不稳定性:第一部分-实验室研究。
Integrative medicine Pub Date : 2021-08-01
William V Judy
{"title":"The Instability of the Lipid-Soluble Antioxidant Ubiquinol: Part 1-Lab Studies.","authors":"William V Judy","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Coenzyme Q10 (CoQ10) is a popular nutritional supplement that is available in both the oxidized and reduced form. The marketing of CoQ10 to physicians often asserts that one form is superior to the other. This study was designed to compare and contrast the stability, absorption and claims made for the reduced form of CoQ10 (ubiquinol) compared with the oxidized form (ubiquinone). There is a need for studies that examine the contents of commercially available ubiquinol products microscopically at room, body and 50°C temperatures. There is also a need for studies of the state of the ubiquinol contents when exposed to a 2.2 pH solution that simulates stomach acidity and an 8.2 pH solution that simulates acidity in the duodenum.</p><p><strong>Methods: </strong>An investigation of the instability of ubiquinol supplements was conducted via an <i>in vitro</i> study of 13 ubiquinol products marketed in the United States that measured the extent of the conversion of the ubiquinol content to ubiquinone, when the ubiquinol was squeezed out of the capsule at room temperature and when the ubiquinol contents were exposed to a 2.2 pH solution and an 8.2 pH solution.</p><p><strong>Results: </strong>In the <i>in vitro</i> study, the percentage of ubiquinol converted to ubiquinone at body temperature was greatest in the 8.2 pH simulated small intestinal juice: 76%. The percentage of ubiquinol converted to ubiquinone at body temperature in the 2.2 pH gastric juice that simulated conditions in the stomach was 54%.</p><p><strong>Conclusions: </strong>Ubiquinol in commercial nutritional supplements is fairly stable inside the gelatin capsule but unstable in gastric and small intestine digestive fluids. Based on the data from the lab studies, most of the ubiquinol from the capsule will be converted to ubiquinone prior to reaching the absorption cells in the small intestines. Animal studies are needed to test this hypothesis.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"24-28"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483252/pdf/imcj-20-24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Discovery that Reframes the Whole of Global Healthcare in the 21st Century: The Importance of the Imprintome. 重塑21世纪整个全球医疗保健的发现:印记组的重要性。
Integrative medicine Pub Date : 2021-08-01
Jeffrey S Bland
{"title":"A Discovery that Reframes the Whole of Global Healthcare in the 21st Century: The Importance of the Imprintome.","authors":"Jeffrey S Bland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Within the genome exists a specific subset of genes whose expression is controlled by epigenetic marks. These tags can be modified by lifestyle factors including diet, behavior, environment and social interactions. Differences in genetic expression, despite identical genes, is explained in part through metastable epialleles-alleles that, while genetically indistinguishable, are variably expressed as a function of epigenetic modification. As a group, these metastable epialleles have been given a unique descriptive name: the imprintome. This breakthrough in understanding genetic expression has led to a wider recognition that our genes are fundamentally controlled at two levels. One is the hardware of the genetic code, which is modified slowly by natural selection through mutational changes in the genome over centuries of time. The other is the software that controls the expression of our genetic code, converting nucleotide sequences into phenotype in response to the imprinting of our epigenome. Acting as a rapid translator for real time changes, the imprintome responds to environmental and lifestyle inputs by genomic methylation and histone modifications that affect promoter accessibility and transcription factor activity. In application, this understanding of the plasticity of the imprintome necessitates a rethinking of both health and disease states. It's a concept that cuts across all forms of healthcare: physical, metabolic, and cognitive-behavioral interventions. But at the same time, it is an aggregating concept-one that brings disciplines together to collaborate on the personalization of health and the delivery of truly individualized care. This article reviews the development of the concept of the imprintome, as well as clinical studies supporting its importance as a potential driver of change in global health care.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483255/pdf/imcj-20-18.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Unimportant" Molecules?-Part 1. “不重要”分子?- 1所示。
Integrative medicine Pub Date : 2021-08-01
Joseph Pizzorno
{"title":"\"Unimportant\" Molecules?-Part 1.","authors":"Joseph Pizzorno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>About a century ago when research into the nutritional components of food began, scientists were limited by the technology and physiological understanding of the time. Nonetheless, this pioneering research revealed the importance of many nutrients for the maintenance of life and prevention of overt deficiency diseases. Unfortunately, the necessary simplifications led to the unrecognized assumption that the constituents in food not required for life were not important. This justified growing food chemically rather than organically because essential nutrients were largely (but not entirely) conserved. However, as technology advanced-especially at the turn of this century-much was revealed. Nutrients considered single molecules when discovered were now realized to represent multiple variants and vitamers with significantly different physiological effects, and many of the molecules considered \"unimportant\" have huge impacts on health and resistance to disease.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"8-16"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483254/pdf/imcj-20-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Growing Evidence of a Proven Mechanism Shows Vitamin K2 Can Impact Health Conditions Beyond Bone and Cardiovascular. 越来越多的证据表明，维生素K2可以影响骨骼和心血管以外的健康状况。
Integrative medicine Pub Date : 2021-08-01
Katarzyna Maresz
{"title":"Growing Evidence of a Proven Mechanism Shows Vitamin K2 Can Impact Health Conditions Beyond Bone and Cardiovascular.","authors":"Katarzyna Maresz","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483258/pdf/imcj-20-34.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthful Living. 健康的生活。
Integrative medicine Pub Date : 2019-06-01 DOI: 10.1001/jama.1935.02760460067024
G. Cody
{"title":"Healthful Living.","authors":"G. Cody","doi":"10.1001/jama.1935.02760460067024","DOIUrl":"https://doi.org/10.1001/jama.1935.02760460067024","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"72 1","pages":"44-45"},"PeriodicalIF":0.0,"publicationDate":"2019-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85362526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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