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Conversation with Joseph Pizzorno, ND, Part 2. 与约瑟夫-皮佐诺（Joseph Pizzorno）的对话，第 2 部分。
Integrative medicine Pub Date : 2024-11-01
Sheldon Baker
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引用次数: 0
Blastocystis hominis; Friend or Foe. 人腔囊泡菌；是敌是友。
Integrative medicine Pub Date : 2024-11-01
Gavin Guard
{"title":"Blastocystis hominis; Friend or Foe.","authors":"Gavin Guard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p><i>Blastocystis hominis (B. hominis)</i> remains the most common parasite identified through stool examination. A clinician will undoubtedly encounter the presence of this parasite numerous times in their career. Thus, it is vital to know if this organism is a 'friend or foe', or in other words, whether it is a commensal or a pathogen. This will help clinicians decide whether to treat or not. This literature review discusses the best available evidence of the association of <i>B. hominis</i> and two diseases- irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). Particularly, focus has been paid to the effect of antimicrobial therapy in improving disease activity/symptoms and concluding on the pathogenicity of <i>B. hominis</i> based on <i>in vitro</i>, observational studies, and randomized controlled trials. Most importantly, the review presents a concise set of recommendations for when and how to treat <i>B. hominis</i> in a patient presenting gastrointestinal ailments.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 5","pages":"28-33"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lifestyle Medicine and the Microbiome: Holistic Prevention and Treatment. 生活方式医学与微生物组：整体预防和治疗。
Integrative medicine Pub Date : 2024-11-01
Shawn Manske
{"title":"Lifestyle Medicine and the Microbiome: Holistic Prevention and Treatment.","authors":"Shawn Manske","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 5","pages":"10-14"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Provoked Seizure Triggered By Electrolyte Imbalance And Substance Use: A Case Report. 电解质失衡和药物使用引发的诱发性癫痫发作：病例报告。
Integrative medicine Pub Date : 2024-11-01
Sierra Solnick
{"title":"Provoked Seizure Triggered By Electrolyte Imbalance And Substance Use: A Case Report.","authors":"Sierra Solnick","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This case report explores the diagnostic challenges in evaluating first-time seizures by highlighting the importance of differentiating between provoked and unprovoked seizures. The patient, a 65-year-old female, experienced her first seizure during a yoga retreat in Costa Rica, influenced by a perfect storm of overlapping factors such as traveler's diarrhea, alcohol consumption, and THC use. Comprehensive evaluation and laboratory assessments revealed an elevated hematocrit and borderline magnesium deficiency. Despite limitations in reporting accuracy and the lack of immediate medical transfer, these findings did not hinder the diagnostic process. This episode, classified as a provoked seizure, highlights the necessity of a detailed case history when evaluating a presumed first-time seizure, targeted electrolyte assessment, and hydration strategies to inform clinical decision-making.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 5","pages":"34-36"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552962/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal Permeability In Subjects With Rheumatoid Arthritis: A Critical Therapeutic Priority. 类风湿关节炎患者的肠道渗透性：治疗的当务之急
Integrative medicine Pub Date : 2024-11-01
Thomas G Guilliams, Jill L Weintraub, Myles Spar
{"title":"Intestinal Permeability In Subjects With Rheumatoid Arthritis: A Critical Therapeutic Priority.","authors":"Thomas G Guilliams, Jill L Weintraub, Myles Spar","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rheumatoid arthritis is increasingly being recognized as the synovial manifestation of a group of systemic autoinflammatory conditions known as immune-mediated inflammatory diseases. While each of these conditions displays unique diagnostic signs and symptoms based on the tissue targeted by inflammation, most immune-mediated inflammatory diseases share common features, including their immune-signaling pathways. Owing to these similarities, great advances have emerged in the past few decades using therapies designed to block downstream inflammatory mediators (eg, cytokine-blocking biologics, Janus Kinase (JAK) inhibitors). Unfortunately, fewer advances have been made in therapies that have the potential to target the upstream antecedents and triggers of these complex inflammatory diseases, such as the immunologic chain of events triggered by intestinal hyperpermeability (ie, leaky gut) or gastrointestinal dysbiosis (ie, alterations in the gut microbiota). In the past few decades, intestinal hyperpermeability has emerged as an important antecedent for a wide range of chronic immunological and metabolic conditions, including celiac disease, obesity, cardiovascular disease, and a number of immune-mediated inflammatory diseases such as inflammatory bowel disease, psoriasis, and rheumatoid arthritis. In this narrative review, we discuss the growing awareness that biomarkers of intestinal permeability are frequently associated with non-gastrointestinal immune-mediated inflammatory diseases, particularly those associated with the gut-joint axis, such as rheumatoid arthritis. We suggest that measures of intestinal permeability, along with lifestyle and nutrient interventions that target gut-barrier function, may be important adjunctive clinical tools to help patients with rheumatoid arthritis achieve and maintain remission.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 5","pages":"16-26"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552960/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Interview with Dr. William Parker on the Connection between Acetaminophen and Autism. 就对乙酰氨基酚与自闭症之间的联系采访威廉-帕克博士。
Integrative medicine Pub Date : 2024-11-01
Sheldon Baker
{"title":"An Interview with Dr. William Parker on the Connection between Acetaminophen and Autism.","authors":"Sheldon Baker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 5","pages":"42-47"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11552961/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142635773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Microplastics and Nanoplastics on Human Health. 微塑料和纳米塑料对人类健康的影响。
Integrative medicine Pub Date : 2024-09-01
Lyn Patrick, Joseph Pizzorno
{"title":"Impact of Microplastics and Nanoplastics on Human Health.","authors":"Lyn Patrick, Joseph Pizzorno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microplastics and nanoplastics are pervasive in the environment and pollute every tissue in the body. Emerging research demonstrates a positive correlation between tissue concentrations of microplastics and several common diseases. The sources of exposure are well understood and can be controlled. However, there appear to be no clinical trials for eliminating microplastics from tissues.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 4","pages":"6-9"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conversation with Joseph Pizzorno, ND. 与 ND.Joseph Pizzorno 对话。
Integrative medicine Pub Date : 2024-09-01
Sheldon Baker
{"title":"Conversation with Joseph Pizzorno, ND.","authors":"Sheldon Baker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 4","pages":"40-43"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
NeoGenesis MB-1 with CRISPR Technology Reduces the Effects of the Viruses (Phages) Associated with Acne - Case Report. 采用 CRISPR 技术的 NeoGenesis MB-1 减少了与痤疮有关的病毒（噬菌体）的影响 - 病例报告。
Integrative medicine Pub Date : 2024-09-01
Greg Maguire, Steven T McGee
{"title":"NeoGenesis MB-1 with CRISPR Technology Reduces the Effects of the Viruses (Phages) Associated with Acne - Case Report.","authors":"Greg Maguire, Steven T McGee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We present a case of acne successfully treated with a topical spray containing live bacteria. The live bacteria used in the spray contain CRISPR, and adaptive immune system in the bacteria that are used to disable viral replication. Because acne skin contains bacteria in the microbiome where a shift toward non-CRISPR bacteria occurs, these bacteria are susceptible to bacteriophage infection and lysogeny. Normalizing the bacterial microbiome to one containing more CRISPR-containing bacteria renormalizes the microbiome by killing inflammation-causing bacteriophage infecting the non-CRISPR bacteria associated with acne.</p>","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 4","pages":"34-38"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441580/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Review of Urogynecology and Women's Health. 泌尿妇科与妇女健康综述》。
Integrative medicine Pub Date : 2024-09-01
Sheldon Baker
{"title":"A Review of Urogynecology and Women's Health.","authors":"Sheldon Baker","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"23 4","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441586/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142361370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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