Integrative medicine最新文献_第9页

Naturopathic Approach to Functional Dyspepsia: A Case Report. 自然疗法治疗功能性消化不良1例。

Integrative medicine Pub Date : 2021-10-01

Jared C Pistoia, Loch Chandler

{"title":"Naturopathic Approach to Functional Dyspepsia: A Case Report.","authors":"Jared C Pistoia, Loch Chandler","doi":"","DOIUrl":"","url":null,"abstract":"Functional dyspepsia is a common presenting concern that includes symptoms such as gastrointestinal reflux, postprandial bloating, and abdominal pain. Aside from mainstay conventional therapies such as proton pump inhibitors and antacid tablets that seek to manage symptoms, naturopathic therapies can similarly offer symptom relief and simultaneously address factors underlying functional digestive disturbances. In this case, a 25-year-old female and first year graduate student presented with abdominal bloating, epigastric pain, flatulence, eructations, reflux, and straining with stool. Onset of symptoms occurred after her transition to graduate school, which resulted in a more stressful and rigorous workload, time-pressured eating habits, and a dearth of whole food consumption. Physical exam findings were unremarkable except for moderate epigastric pain, hyperactive bowel sounds, and a geographic tongue. While she met all the Rome IV criteria for functional dyspepsia, clinical findings did not warrant referral for endoscopy to rule out structural/organic causes of disease. As a result, therapeutic interventions consisted of an elimination diet and the use of apple cider vinegar and L-glutamine powder, in addition to a compounded homeopathic formula containing UNDA #4 and Nux vomica. Within 1 week, the patient reported significant improvement in presenting concerns, and within 1 month had denied the presence of every presenting symptom except for straining with stool. This case demonstrates that a naturopathic approach to functional dyspepsia can offer significant symptom relief as soon as 1 week after treatment, and that an effective treatment plan can be offered to patients in 1 visit lasting no longer than 60 minutes. Furthermore, compliant patients can experience a significant improvement in overall gastrointestinal function as early as 1 month after treatment initiation.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":"20 5","pages":"32-36"},"PeriodicalIF":0.0,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8594970/pdf/imcj-20-32.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39754306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Letters. 信件。

Integrative medicine Pub Date : 2021-10-01

Alan Gaby

引用次数: 0

Conversation with Dale Bredesen, MD. 对话Dale Bredesen, MD

Integrative medicine Pub Date : 2021-10-01

Dick Benson

引用次数: 0

Irritable Bowel Syndrome and Depression: A Case Report. 肠易激综合征与抑郁:1例报告。

Integrative medicine Pub Date : 2021-10-01

Joshuan Baughman, Jacquelyn Ambrogio, Mahfam Motevalli

引用次数: 0

Gu Syndrome, Lurking Pathogens, and Long Covid: An Old Take on a New Disease. 顾氏综合症、潜伏病原体和长期感染:一种新的疾病。

Integrative medicine Pub Date : 2021-10-01

Heidi Lovie

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Conversation with James Greenblatt, MD-Integrative Medicine for Mental Health Conference. 对话詹姆斯格林布拉特，医学博士，心理健康会议的综合医学。

Integrative medicine Pub Date : 2021-08-01

Dick Benson

引用次数: 0

Ahiflower Oil-The Rising GLA Alternative to Evening Primrose for Women & Vegans. Ahiflower油-为女性和素食者提供月见草的GLA替代品。

Integrative medicine Pub Date : 2021-08-01

Andrew Myers, Greg Cumberford

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The Instability of the Lipid-Soluble Antioxidant Ubiquinol: Part 1-Lab Studies. 脂溶性抗氧化剂泛醇的不稳定性:第一部分-实验室研究。

Integrative medicine Pub Date : 2021-08-01

William V Judy

{"title":"The Instability of the Lipid-Soluble Antioxidant Ubiquinol: Part 1-Lab Studies.","authors":"William V Judy","doi":"","DOIUrl":"","url":null,"abstract":"Background: Coenzyme Q10 (CoQ10) is a popular nutritional supplement that is available in both the oxidized and reduced form. The marketing of CoQ10 to physicians often asserts that one form is superior to the other. This study was designed to compare and contrast the stability, absorption and claims made for the reduced form of CoQ10 (ubiquinol) compared with the oxidized form (ubiquinone). There is a need for studies that examine the contents of commercially available ubiquinol products microscopically at room, body and 50°C temperatures. There is also a need for studies of the state of the ubiquinol contents when exposed to a 2.2 pH solution that simulates stomach acidity and an 8.2 pH solution that simulates acidity in the duodenum.Methods: An investigation of the instability of ubiquinol supplements was conducted via an in vitro study of 13 ubiquinol products marketed in the United States that measured the extent of the conversion of the ubiquinol content to ubiquinone, when the ubiquinol was squeezed out of the capsule at room temperature and when the ubiquinol contents were exposed to a 2.2 pH solution and an 8.2 pH solution.Results: In the in vitro study, the percentage of ubiquinol converted to ubiquinone at body temperature was greatest in the 8.2 pH simulated small intestinal juice: 76%. The percentage of ubiquinol converted to ubiquinone at body temperature in the 2.2 pH gastric juice that simulated conditions in the stomach was 54%.Conclusions: Ubiquinol in commercial nutritional supplements is fairly stable inside the gelatin capsule but unstable in gastric and small intestine digestive fluids. Based on the data from the lab studies, most of the ubiquinol from the capsule will be converted to ubiquinone prior to reaching the absorption cells in the small intestines. Animal studies are needed to test this hypothesis.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"24-28"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483252/pdf/imcj-20-24.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Discovery that Reframes the Whole of Global Healthcare in the 21st Century: The Importance of the Imprintome. 重塑21世纪整个全球医疗保健的发现:印记组的重要性。

Integrative medicine Pub Date : 2021-08-01

Jeffrey S Bland

{"title":"A Discovery that Reframes the Whole of Global Healthcare in the 21st Century: The Importance of the Imprintome.","authors":"Jeffrey S Bland","doi":"","DOIUrl":"","url":null,"abstract":"Within the genome exists a specific subset of genes whose expression is controlled by epigenetic marks. These tags can be modified by lifestyle factors including diet, behavior, environment and social interactions. Differences in genetic expression, despite identical genes, is explained in part through metastable epialleles-alleles that, while genetically indistinguishable, are variably expressed as a function of epigenetic modification. As a group, these metastable epialleles have been given a unique descriptive name: the imprintome. This breakthrough in understanding genetic expression has led to a wider recognition that our genes are fundamentally controlled at two levels. One is the hardware of the genetic code, which is modified slowly by natural selection through mutational changes in the genome over centuries of time. The other is the software that controls the expression of our genetic code, converting nucleotide sequences into phenotype in response to the imprinting of our epigenome. Acting as a rapid translator for real time changes, the imprintome responds to environmental and lifestyle inputs by genomic methylation and histone modifications that affect promoter accessibility and transcription factor activity. In application, this understanding of the plasticity of the imprintome necessitates a rethinking of both health and disease states. It's a concept that cuts across all forms of healthcare: physical, metabolic, and cognitive-behavioral interventions. But at the same time, it is an aggregating concept-one that brings disciplines together to collaborate on the personalization of health and the delivery of truly individualized care. This article reviews the development of the concept of the imprintome, as well as clinical studies supporting its importance as a potential driver of change in global health care.","PeriodicalId":13593,"journal":{"name":"Integrative medicine","volume":" ","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"2021-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8483255/pdf/imcj-20-18.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39481045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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"Unimportant" Molecules?-Part 1. “不重要”分子?- 1所示。

Integrative medicine Pub Date : 2021-08-01

Joseph Pizzorno

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