Dineshan Km, N. Madhavan, S. More, Edikkula Varghese, V. Vishal, Felix S Cardosa
{"title":"Factors affecting urine leak after percutaneous nephrolithotomy: a single centre prospective study","authors":"Dineshan Km, N. Madhavan, S. More, Edikkula Varghese, V. Vishal, Felix S Cardosa","doi":"10.15520/IJMHS.V10I07.3038","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3038","url":null,"abstract":"PCNL was first performed in late 1970s and it heralded a breakthrough in the treatment of renal stones.1 Although retrograde intrarenal surgery (RIRS) is widely applied in upper urinary stones, the technique of percutaneous nephrolithotomy (PCNL) is still the treatment of choice for large and complex stones","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75297797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Surgical treatment of sacrococcygeal pilonidal sinus with the Limberg transposition flap","authors":"S. Bari","doi":"10.15520/IJMHS.V10I07.3039","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3039","url":null,"abstract":"Background: Pilonidal sinus disease is a common condition usually affecting young individuals and has been conventionally treated by open excision technique. Rhomboid Limberg is a transposition flap that has been pleaded for treatment of this condition. Aim: To study the outcome of Rhomboid excision with Limberg flap closure for the treatment of Sacrococcygeal Pilonidal sinus. Material and Methods: The study was conducted prospectively in the department of surgery Skims Medical College Srinagar from March 2014 to February 2019 and total of 55 patients with primary or recurrent pilonidal sinus disease were studied. Results: The average operative time was 60 minutes (range 50-80 minutes) Postoperative stay of patients in the hospital was 3-4 days.The complications were seen in total of four patients which included Seroma and mild gaping of the wound in one patient each and dehiscence in two patients. None of the patients had recurrence till date.Conclusions: Rhomboid excision with Limberg flap transposition is an effective surgical technique for management of pilonidal sinus. \u0000Keywords: Pilonidal sinus, Limberg flap, rhomboid transposition flap, fasciocutaneous flap,","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84208761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between Alpha Fetoprotein (AFP) Levels and Characteristics of Liver Lesions Using Computed Tomography (CT) scan in Hepatocellular Carcinoma: a Study at Dr. Hasan Sadikin Central General Hospital Bandung 2019","authors":"R. Soetikno, Iin Hatta, Leni Santiana, D. K. Dewi","doi":"10.15520/IJMHS.V10I07.3027","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3027","url":null,"abstract":"Introduction: Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver which is about 75% - 85%. The diagnosis of HCC is determined based on several factors, including the background of chronic liver disease, tumor markers, and imaging diagnosis. There are three main growth patterns of HCC that can be seen on computed tomography (CT) scan : massive, nodular, and diffuse infiltrative. HCC is locally invasive and tends to invade the portal vein, inferior vena cava and bile duct. Alpha fetoprotein (AFP) is one of the tumor markers used for early diagnosis of KSH and plays an important role in the development and progression of HCC. \u0000Objective : To determine the correlation between alpha fetoprotein levels with characteristics of liver lesions using CT scan examination in HCC patients. \u0000Methods : This study was an observational analytic study with a cross-sectional design. Sampling was done retrospectively by collecting medical record data and the results of abdominal CT scan readings from January to December 2019. The study was conducted at the Department of Radiology, Department of Clinical Pathology and Installation of Medical Records-SIRS Hospital Dr. Hasan Sadikin Bandung in February - April 2020. Univariable analysis was carried out to see the description of the proportion of each variable to be presented descriptively, which could be explained into descriptive analysis and hypothesis testing. \u0000Results : There were 63 subjects, 48 men (76.2%), 15 women (23.8%), with the youngest age of 21 years, the oldest 86 years with an average age of 53.44 years. The highest average AFP levels were found in the group of patients with diffuse infiltrative growth patterns 93064.84 ± 177486,301 and the presence of a thrombus in the portal vein of 78770.98 ± 88358,791. The results of statistical tests using the Mann Whitney Test showed that there were significant differences between the levels of AFP and the growth pattern of liver lesions in HCC patients based on the results of the CT scan with a value of p = 0.040 (p?0.05) and there were significant differences between the levels of AFP and portal vein thrombus in HCC patients based on the results of CT scan examination with a value of p = 0.040 (p?0.05). \u0000Conclusion : There is a significant correlation between AFP levels with the characteristics of liver lesions specifically the form of growth patterns and the presence of portal venous thrombus using CT scan examination of HCC patients in dr. Hasan Sadikin General Hospital. \u0000Keywords : Hepatocellular carcinoma, Alpha fetoprotein, CT scan","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88438829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vineet Golchha, R. Paul, Pooja Sharma, Deepti Yadav, I. Sharma, Mudit Gupta, V. Gulia
{"title":"PSYCHOLOGICAL IMPACT OF COVID 19 PANDEMIC ON DENTAL STUDENTS","authors":"Vineet Golchha, R. Paul, Pooja Sharma, Deepti Yadav, I. Sharma, Mudit Gupta, V. Gulia","doi":"10.15520/IJMHS.V10I07.3025","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3025","url":null,"abstract":"Background : The coronavirus disease 2019 (COVID-19) which has spread rampantly to every country of the world. Dentists and dental students being amongst the professions with higher risks are under tremendous stress. Stress has been linked to serious side effects such as emotional exhaustion, anxiety, or depression. Therefore, our aim was to measure the levels of depression, anxiety and stress in dental students using the DASS-21 and to compare it with the sense of insecurity towards profession future due to Covid 19. \u0000Methodology: The data was collected through well-structured Google form from 1384 dental students studying in Delhi NCR. The entire form had two components. The first part of the form collected the demographic information of the students whereas the second part of questionnaire consisted of psychological evaluation using well established scale DASS 21. \u0000Result : The study showed 4% of the students with severe levels of depression,6% indicated severe level of anxiety, and 4% had severe stress. 87.2% of the students were insecure for their professional future due to spread of Covid19 and a significant correlation was found between future professional insecurity and depression, anxiety and stress \u0000Conclusion : High levels of depression, anxiety and stress was seen in undergraduate dental students which wass worsened by the current pandemic .There is a need to evolve with the current COVID 19 pandemic , impart confidence among them and find ways to decrease the levels of stress among these future dentists. \u0000 \u0000Keywords: COVID19, Stress, dental students , DASS 21.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76822349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparative Study on Effect of Yoga Among Prediabetics on Progression of Cardiovascular Risk Factors","authors":"N. Saboo","doi":"10.15520/IJMHS.V10I07.3023","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3023","url":null,"abstract":"Introduction: Diabetes is a chronic illness that requires continuing medical and healthcare and self education and life style modifications. Moreover, the disease manifestations start in the early stages of diabetes and before it gets established as a full blown condition in the pre-stage called prediabetes. Lifestyle interventions such as engagement in muscle-strengthening and conditioning activities (resistance exercise, yoga, stretching, toning) is associated with a lower risk of prediabetes and type 2 diabetes, Yoga constitutes asanas, regulated breathing (pranayama), and awareness of yoga sutras (principles) that govern the mind and preventing progression of prediabetes to type 2 diabetes. This comparative study highlights importance of six month yoga intervention in two groups of prediabetic subjects ,one group which perform yoga asans at home by the help of cd and video recording and other group which perform yoga asans at yoga centers in presence of yoga instructors, and use its as a tool for primary prevention of diabetes. \u0000Methodology: This was a comparative Interventional study conducted at RUHS college of Medical Sciences and Associated Hospital in Jaipur city. The design of study was Prospective Intervention Comparative Study. A total of 202 prediabetic subjects of age group 30 to 50 years were recruited from Jaipuria Hospital. These were divided into two groups Cd and video recording group (Group A, n=101) were divided in control 51 and study group 51 which perform yoga asans by the help of cd and video recording at their home and other( Group B , n=101) divided in control 51 and study group 51 engaged in yoga session at the yoga centers . Protocol of yoga asans were same in both groups. \u0000Results: Yoga intervention resulted in a significant decline in blood glucose ( p< .001) in cd and video recording group and yoga center group, Glycated hemoglobin ( p <.01) in cd and video recording group, lipid profile Cholesterol (p<.01) in cd and video recording group and (p<.001) in yoga center group ,Triglyceride( p<.01) in cd and video recording group and ( p<.001) in yoga center group but HDL ( p value =.2) in cd and video recordin group and ( p value =.86) in yoga center group but statistically non significant relative to the control group. \u0000Conclusion: Six month yoga intervention to be helpful in control of blood glucose and lipid profile in cd and video recording and yoga center groups of prediabetes subjects. \u0000Yoga can be used as effective therapy in improving glycemic parameters i.e blood glucose and glycated haemoglobin and lipid profile. Comparative result showed that yoga beneficial in both the group but it would be better in yoga centers in terms of guidance by yoga instructor ,regularity at particular place and time , motivation from community . \u0000Key words: Prediabetes, yoga, cardiovascular risk","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88534563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vinita H. Belsare, Sarika C. Munghate, A. Tadas, Hrishikesh Belsare, S. Agrawal
{"title":"IMPACT OF SMART PHONE USAGE ON SLEEP, MELATONIN AND ITS CORRELATION WITH ANXIETY AND DEPRRESSION IN FIRST YEAR MEDICAL STUDENTS","authors":"Vinita H. Belsare, Sarika C. Munghate, A. Tadas, Hrishikesh Belsare, S. Agrawal","doi":"10.15520/IJMHS.V10I07.3020","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I07.3020","url":null,"abstract":"Significant increase in the smart phone use had been associated with various effect on the health. Various theories have proposed for sleep, circadian rhythm disturbances and studies have shown effect on melatonin levels and mental health. The objective of this study was to evaluate the effect of smart phone on sleep time, sleep duration and serum melatonin levels. To determine academic and non-academic usage and its correlation with academic performance. Effect of smart phone usage on the mental health i.e. anxiety and depression in young adult first year medical students. Sample size was 100 , 3 were absent. A brief questionaries’ was asked to all the study group regarding usage of mobile phone and sleep hours in night. 9 A.M Morning fasting blood samples were taken and serum melatonin was estimated by ELISA kit. Hamilton’s anxiety scale and Hamilton’s depression scale was applied to the study group. Study had shown the smart phone usage was having an impact on sleep. Study have shown late bedtime, long sleep duration in the students with high user group. This may be result of sleep displacement and circadian rhythm disturbances. Low levels of melatonin in high users as compared to low users, which may be due to exposure EMF leading to circadian rhythm disturbance. The academic and the non- academic usage was significantly high in high users, but with no significant difference in the academic performance. High academic usage of smart phone may lead to better academic performance despite of late bedtime. Non-academic usage of smart phone may cause emotional arousal leading to anxiety. Anxiety and depression score was high in high users group, but the difference was not statistically significant. But it is not clearly understood whether the smart usage is responsible for anxiety and depression or anxiety and depression causes high smart phone usage. Smartphones affect the academic lives of the undergraduate medical students. This study can conclude with the fact that using smartphones made an impact on students both positively and negatively. \u0000KEYWORDS: - Smart phone, sleep, Melatonin, Anxiety, Depression","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91550577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Raja, Malarvizhi Subramani, Amirtha Santhi Seenivasan
{"title":"Compliance of ventilator associated pneumonia care bundle by staff nurses in critical care units","authors":"N. Raja, Malarvizhi Subramani, Amirtha Santhi Seenivasan","doi":"10.15520/IJMHS.V10I06.3017","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I06.3017","url":null,"abstract":"INTRODUCTION: Ventilator-associated pneumonia (VAP) is a type of hospital-acquired pneumonia that occurs in patients who are mechanically ventilated for more than 48 hours. VAP is the leading cause of nosocomial infections in patients in intensive care units (ICUs). The pathogenesis of VAP originates from microbial pathogens that are aspirated through the tracheal tube cuff and into the lower respiratory tract. Subsequent colonization and overwhelming of the host's mechanical, body fluids, and cellular defense mechanisms leads to the development of VAP. Objectives:1. To assess the compliance on VAP care Bundle by staff nurses in critical care units.2. To identify the reason for the non-compliance on VAP care bundle.3.To associate the level of compliance on VAP care bundle with demographic variables. \u0000Material and Methods: A Descriptive study conducted in critical care units at a tertiary teaching hospital at Puducherry. Institutional review board permission was obtained. The data collection period was one month in the year 2018. The population was nurses who are taking care of mechanical ventilator patients. Samples were selected by census method. The sample size was 50. After getting group consent (verbal consent) from each staff nurses, they were observed by using observational checklist to assess the compliance of VAP care bundle in critical care units. After continuous 3 observations, the participant information sheet was provided and written consent was obtained from each staff nurses. After that the data related to demographic variables and self administered questionnaires on compliance of VAP care bundle was administered over a period of 20 minutes for every participant. Results: In the present study majority 76% (38) staff nurses had average level of compliance to VAP care bundle, 72% (36) of the staff nurses belongs to the age group of 22-25 years,86% (43) of them were females ,96% (48) had completed BSc Nursing,46% (23) of them had 13-36 months of working experience and 58%(29) had not attended CNE regarding VAP care bundle. Conclusion: The present study assessed the level of compliance of VAP care bundle by staff nurses in critical care units. The practices were observed by using observational checklist and the reasons for non compliance to VAP care bundle given by staff nurses were expensive equipment, lack of awareness and dependence on doctor’s order. The study concludes that the level of compliance among majority of staff nurses were average, so there is need for improvement in nurses performance in implementing VAP care bundle protocol in critical care units.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"25 1","pages":"1050-1054"},"PeriodicalIF":0.0,"publicationDate":"2020-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86689909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Madhulika Sharma, Mrunal S Aley, V. Kerudi, S. Jakati, S. Saxena, A. Rathod
{"title":"STRESS AND STRAIN DISTRIBUTION IN TEMPOROMANDIBULAR JOINT AFTER MANDIBULAR GROWTH RETARDATION: A THREE DIMENSIONAL FINITE ELEMENT STUDY","authors":"Madhulika Sharma, Mrunal S Aley, V. Kerudi, S. Jakati, S. Saxena, A. Rathod","doi":"10.15520/IJMHS.V10I06.3018","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I06.3018","url":null,"abstract":"Introduction: Angle’s Class III malocclusion occurs when lower teeth occlude mesial to their normal relationship or ahead by one premolar width or even more in extreme cases. Etiology of Skeletal Class III malocclusion is considered as multifactorial because of an interaction of both hereditary (genotype) and environmental factors (phenotype). Orthopedic chin cup used in treatment of Class III malocclusion apply force on temporomandibular joint to inhibit or redirect condylar growth. The effects of an orthopedic appliance essentially depend on magnitude and direction of force. Hence, the purpose of study was to analyze and compare the stress and strain distribution in temporomandibular joint after growth retardation of the mandible by orthopedic procedure.Material and Methodology. Construction of the geometric model. b. Conversion of geometric model to finite element model. c. Material Property Data Representation. d. Defining the boundary condition. e. Application of forces. f. Evaluation of stress and strain distribution.Results & FEM study reveals changes in stress and strain generation at different anatomical locations after applying force at symphysis region. The pogonion condyle axis is key for direction of forces to induce orthopaedic effects generated by chin cup. However, in clinical situation, study can be utilized for direction planning of chin cup force with anticipated results but magnitude has to be calculated by operator withstanding in physiologic limits of patient. The orthopaedic force can be started with 300 g per side and incrementally increased according to clinical demand, physiologic limits and skeletal age of patient to avoid untoward results of orthopaedic force appliedKey words: finite element analysis, chin cup, class III, stress & strain on TMJ","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"93 1","pages":"1055-1068"},"PeriodicalIF":0.0,"publicationDate":"2020-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80018155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chandrasinh Rajput, S. Mehta, Harshvardhan Chaudhary, P. Sutariya, Hiren Rana
{"title":"THE STUDY OF ETIOLOGICAL FACTORS ASSOCIATED WITH DENTURE STOMATITIS IN AN INDIAN POPULATION","authors":"Chandrasinh Rajput, S. Mehta, Harshvardhan Chaudhary, P. Sutariya, Hiren Rana","doi":"10.15520/IJMHS.V10I06.3016","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I06.3016","url":null,"abstract":"Aim: The aim of this study is to find out the possible etiological factors for denture stomatitis (DS) in completely edentulous denture wearing patients by cross-sectional study. \u0000Material and Methods: Population for this cross-sectional study consisted of 60 completely edentulous denture wearing patients residing in Ahmedabad, India. Data collection was done by questionnaire, oral examination and denture evaluation. All the data were analyzed using the software SPSS. Qualitative data were analyzed by Chi-square test and quantative data were analyzed by student t test. \u0000Results: This study showed 28% prevalence of denture stomatitis (17 out of 60 examined patients) in this study population. Many factors can be associated with DS, but present study showed significant correlation between Continuous denture wearing, Age of denture, Denture hygiene, Candidiasis, Lack of denture stability, Decrease VDO, High sugar intake, Hypo salivation, Low salivary pH. \u0000Conclusion: Apart from infection, particularly with C.albicans, denture related factors can also cause denture stomatitis and these prosthetic factors appear to play mainly a traumatic role in the occurrence of DS. Patient should be motivated to practice proper denture wearing habits and maintenance of oral hygiene and follow a program of recall and maintenance for continuous monitoring of dentures and oral tissues. \u0000Keywords: Denture stomatitis, Denture hygiene, Retention, Stability, Vertical dimension.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"46 1","pages":"1045-1049"},"PeriodicalIF":0.0,"publicationDate":"2020-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73055213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nivedita Kaorey, M. Mandale, Dr.J D Bhavthankar, J. Humbe
{"title":"Nuclear fractal dimensions - an indicator of nodal metastasis in Oral Squamous Cell Carcinoma","authors":"Nivedita Kaorey, M. Mandale, Dr.J D Bhavthankar, J. Humbe","doi":"10.15520/IJMHS.V10I06.3014","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I06.3014","url":null,"abstract":"Context: Cumulative appraisal of tumor size, lymph node involvementand metastasis is essential for evaluating the prognosis of any cancer.Oral cancer being no exception to this rule also shows lymph nodemetastasis in advanced stages. Oral cancer boasts of certain peculiarmicroscopic features, among which nuclear morphometric changesform a key component. Accuracy in identifying these nuclear changeswill help in better prediction of the prognosis of oral cancer.Fractal measurement is an offshoot of the computer aided image analysiswhich aids in the accurate analysis of the structural properties ofhistopathology specimens.Aims: To evaluate the use of nuclear fractal dimensions (NFD) topredict lymph node metastasis in oral squamous cell carcinoma.Settings and Design: A cross-sectional comparative study was carriedout using archived histopathological tissue specimens of oral squamouscell carcinoma which were then subjected to morphometric analysis.Methods and Material: 30 H&E stained sections of OSCC with andwithout lymph node metastasis were taken for the analysis. The microscopicimages were captured from five representative high power fieldsfrom infiltrated dysplastic epithelial islands in the connective tissue andsubjected to image analysis using Image Pro Premiere software. Wellstained,well-defined and non-overlapping neoplastic nuclei were semimanuallyselected and subjected to fractal analysis.Statistical analysis used: Statistical analysis was done by applyingstudent’s unpaired t-test and ‘p’ value below 0.005 was consideredstatistically significant.Results: A mean Nuclear Fractal Dimension of 1.099\u0006 0.0068 forOSCCs with nodal metastasis as opposed to NFD of 1.055\u00060.0047 forOSCCs devoid of lymph node involvement was observedConclusions: Nuclear fractal dimensions may prove to be a valuableindicator in the assessment of prognosis oral squamous cell carcinoma.Keywords: nuclear fractal dimensions, image analysis, nuclear morphometry","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"11 1","pages":"1036-1039"},"PeriodicalIF":0.0,"publicationDate":"2020-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84279336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}