Innovative Journal of Medical and Health Science最新文献

{"title":"Hand Microbiome And Resistant Strains From Cell Phones Of Health Personnel","authors":"M. Bhaskar, Madhulatha Ck, N. Harshitha","doi":"10.15520/IJMHS.V10I12.3156","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I12.3156","url":null,"abstract":"Purpose:To investigate the hand microbiome of Health Personnel and the flora transferred to their hands from cell phones. \u0000Methods:The study was conducted in a tertiary care hospital over 3 months in 50 health personnel. Their dominant hand was placed on agar plates to establish the hand microbiome. After sanitizing and drying their hands, and using their phones for a few minutes, another handprint was taken to identify the bacteria on the phone. The bacteria were identified by standard microbiologic techniques. \u0000Results:Organisms identified in the normal microbiome included coagulase negative Staphylococci (CoNS, 90%), Klebsiella pneumoniae (16%), E. coli (8%), Staphylococcus aureus (4%), Pseudomonas aeruginosa (2%) and Acinetobacter spp. (2%). CoNS isolated were found to be resistant to co-amoxiclav (41.67%), cotrimoxazole (20.83%), erythromycin (20.83%) and clindamycin (20.83%). Maximum resistance was observed towards co-amoxiclav. The repeat handprint showed the colony count as decreased by four times. Bacteria found were CoNS (92%), E. coli (4%), Enterococcus (4%), Klebsiella (2%) and Acinetobacter (2%). Antibiotic sensitivity was similar here with additional resistance to cefepime and cefoxitin by CoNS. \u0000Conclusion:Hand microbiome of health personnel comprises bacteria that are dangerous to immunocompromised individuals and our phones are effectively transmitting multidrug resistant bacteria to our hands within a few moments of contact. There was also a notable lack of S. aureus in our samples, while many other studies have shown it to be a common nosocomial pathogen, found on hands of health personnel. \u0000Keywords:Hand microbiome, Health Personnel, Antibiotic resistance, cell phone","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90674566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Newborn with Multiple Congenital Anomalies (MCAs)","authors":"Alen Kinyina, Hilda Mavanza, Jasmine Chadewa, Sarah Chamos","doi":"10.15520/IJMHS.V10I11.3145","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I11.3145","url":null,"abstract":"Congenital anomalies are one of the main causes of physical disabilities, stillbirths and neonatal deaths. It Can contribute to long-term disability, which may have significant impacts on individuals, families, health-care systems and societies.  Diagnosis of a child who presents with multiple congenital anomalies both prenatal and postnatal is still a complex issue. We present a complex case of a newborn with multiple congenital anomalies (MCAs) including hydrocephalus, Down syndrome, phocomelia, ectrodactyl and ambiguous genitalia. This is the first case to be reported in Tanzania and among the few cases in World’s English literatures. \u0000Key words: Congenital, Hydrocephalus, Down syndrome, Phocomelia, Ectrodactyl ,Ambiguous genitalia","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"106 1","pages":"1392-1395"},"PeriodicalIF":0.0,"publicationDate":"2020-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86689246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interpretation of Prostatic Biopsy at a tertiary care centre","authors":"R. Agrawal, Alpana Jain, A. Goyal, N. Mehta, N. Gupta","doi":"10.15520/IJMHS.V10I11.3148","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I11.3148","url":null,"abstract":"Introduction: Worldwide prostatic carcinoma is the second most frequently diagnosed cancer and the sixth leading cause of cancer death in males. Prostate-specific antigen (PSA), digital rectal examination, and transrectal ultrasound are the tools most commonly used to screen for prostate cancer. Prostatic biopsy is most often preceded by abnormalities found on digital rectal examination (DRE) or serum prostate specific antigen (S.PSA) elevation. This study was planned to know proportion of malignant and benign lesions in histopathologic examination for prostatic lesions in patient who attend OPD/IPD and to analyze the usefulness of serum PSA & ultrasound examination by histopathological confirmation. \u0000Methods: Patients visited to urology department with urinary incontinence and other complaints were evaluated which includes clinical history, signs and symptoms. Rectal examination of patients was done. Serum PSA level and prostatic biopsy were sent of those who were suspected for prostatic disease. Prostate biopsy was obtained by using any one of the following method 1.Transurethral resection biopsy 2. Transrectal biopsy Trucut biopsy. \u0000Results: Out of 300 cases of prostatic biopsy 265 (88.33%) are benign and 35 (11.66%) cases are malignant lesions. Out of 300 cases, 191 (63.66%) are pure benign prostatic hyperplasia, 48(16%) are BPH with chronic prostatitis and 11(3.66%) are BPH with severe prostatitis. Out of 35 cases of prostatic carcinoma 33 (94.28%) cases are adenocarcinoma and 2 cases (5.71%) are transitional cell carcinoma. Out of 262 cases with clinically benign lesions, 258 cases proved benign histopathologically but 4 cases (1.52%) are diagnose malignant. 151 patients have S.PSA less than 4 ng/ml, out of 151, 149 turned to be benign on histopathological examination. 52 patient have S.PSA above 10 ng/ml, out of these 52 cases, 29 have malignancy in HPE examination. Out of 278 cases diagnosed as benign isoechoic by ultra sonography 262 cases have benign lesion on histologic diagnosis and 16 have malignant lesion. Out of 22 cases diagnosed as malignant (hypoechoic asymmetrical) by ultrasonographicaly 19 proved malignant histologically. \u0000Conclusion: The results of this study indicate that transrectal ultrasound, serum prostate specific antigen and digital rectal examination were good tool to differentiate between malignant and benign lesions of prostate. Proportion of malignancies are quiet significant in prostatic lesions and increased with age. \u0000Key words: Prostae, Malignancy, Biopsy, PSA, DRE","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"28 1","pages":"1396-1401"},"PeriodicalIF":0.0,"publicationDate":"2020-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73708414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Adherence to Anti-Retroviral Therapy (ART) medication among HIV infected patients: A snapshot study at ART Centre, Odisha","authors":"Swetaleena Ashe, D. Routray, S. Mohapatra","doi":"10.15520/IJMHS.V10I11.3144","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I11.3144","url":null,"abstract":"Highly active anti-retroviral therapy (HAART) has now transformed HIV pandemic from “virtual death sentence” to a “chronic manageable disease”. An adherence rate of 95% to ART decreases viral suppression to nearly 78% and is thus ear marked as an optimum therapy for viral suppression. The objectives are to estimate the level and associated factors of adherence (with respect to the five WHO dimensions) to ART among HIV positive patients. \u0000It was a cross-sectional study carried out at the ART center of a tertiary care teaching hospital. Simple random sampling was done from the new enrollment list of the previous 6 months. A total of 120 respondents were interviewed by a pre-designed semi structured questionnaire and analyzed using SPSS. \u0000Majority of the participants (55.1%) aged 26 to 40 years and 57% of them were found to be adherent. Patients aged more than 40 years (OR 11.55), distance < 100 kms from the ART Centre (OR 2.75), dissatisfied with family support (OR 3.42), and those with decreased CD4 count from the previous count (OR 6.56) were found to be highly significantly associated with the probability of being adherent to ART. \u0000Adherence to ART was found among 57% among the study subjects. Elderly patients residing nearer to service delivery centre and those at higher risk of morbidity due to lower CD4 count were found to be some of the major determinants of adherence to ART. Link ART centres and LAC Plus Centres with community level awareness programs are recommended.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83310127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between Perceived Organizational Support and Quality of Nurses’ Work Life at King Fahad Hospital-Saudi Arabia","authors":"S. Malki, G. Hamouda, O. Felemban","doi":"10.15520/ijmhs.v10i10.3136","DOIUrl":"https://doi.org/10.15520/ijmhs.v10i10.3136","url":null,"abstract":"Background: Improving the quality of nurses’ working life is challenging for healthcareorganizations because of its effect on the staff, organizations, and customers. Thedevelopment of supportive environments will enhance the quality of nursing work lifein organizations. However, the association between perceived organizational supportand the quality of working life among nurses was limited information.Aim: This study aims to assess the relationship between perceived organizationalsupport and the quality of nurses’ work life at a King Fahad Hospital Jeddah, SaudiArabia.Methodology: This current study was conducted at King Fahad Hospital, Jeddah,Saudi Arabia. A descriptive correlational design was used. A convenience samplingtechnique was implemented to gather the needed data using a self-report questionnaire.Data was collected using the Survey of Perceived Organizational Support and Brook’Quality of Nursing Work Life Survey. In addition, a demographic questionnaire wasdeveloped by the researcher.Results: About 80.6% of staff nurses showed a moderate POS level, and 63.6% of staffnurses experienced an average level of QNWL. The Pearson correlation coefficientsshowed a statistically significant correlation between POS and overall QNWL (0.541).The correlations between POS and the sub-scales of QNWL came in the range (0.367– 0.521). Also, it found that non-Saudi nurses exhibited higher POS and QNWL levelscompared to Saudi nurses.Conclusion and Recommendation: The study found that perceived organizationalsupport is positively related to QNWL, which means that the higher nurses’ perceivedorganizational support will improve the nurses’ quality of working life. These findingsshould be used by nursing administrations and health policymakers to develop a seriesof organizational support that can improve the quality of working life amongnurses. Future research, further comparative research is needed to examine POS andits relation to QNWL among different healthcare organizations.Key words: Perceived Organizational Support–Quality of Nurses’ Work Life–Qualityof Nursing Work Life–Staff nurses","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72902428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of Breast Cancer Risk Factors and Practices of Breast Self-Examination among Women in Northern Ghana","authors":"A. Buunaaim, W. J. Salisu, Hawawu Hussein, Y. Tolgou, S. Tabiri","doi":"10.15520/IJMHS.V10I10.3119","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I10.3119","url":null,"abstract":"Introduction: Breast cancer remains a major global health concern in both developed and developing countries. The current study aimed to assess the knowledge of risk factors of breast cancer (BC), and the practice of breast self-examination (BSE) among females in the Tamale Metropolis of Northern Ghana. Methods: This is a cross-sectional study involving 1122 participants; consisting of nurses 157 (14.1%), teachers 227 (20.2%), undergraduate university students 339 (30.5%), medical students 95 (8.5%) and market women 304 (27.3%). Using a convenience sampling method to select the participants, we distributed questionnaires to participants which were completed and returned. Results: Most of the participants, 498 (44.4%) were between age 19-25.  The majority were enlightened about BC (93.1%), and BSE (87.6%), 723 (64%) had good knowledge about the risk factors of BC. A total of 857 (76.4%) had previously been taught BSE. However, only 417 (37.2%) were found to practice BSE regularly. Conclusion: The knowledge of BC risk factors and BSE was remarkable, but varied in the various occupational categories. However, only a few participants practiced BSE regularly. There is a need for widespread educational campaigns to educate further and encourage women to practice BSE regularly. The inclusion of men in these crusades is long overdue. Equipped with the knowledge and skills of BSE, men could assist and encourage their spouses to frequently examine themselves. Further research studies will be necessary to ascertain the role of men in championing BSE among their significant others. \u0000Keywords: awareness; breast cancer; breast self-examination; knowledge; practice; Ghana; Tamale","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86843535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EPIs and Immunotherapy – An answer to drug-resistant tuberculosis","authors":"Aindrilla Roy, Arsalan Hussain, K. Sinha, Mahima Praharaju, Sabana Khatun","doi":"10.15520/IJMHS.V10I10.3115","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I10.3115","url":null,"abstract":"Tuberculosis (TB), primarily caused by Mycobacterium tuberculosis (Mtb) remains one of the fatal contagious diseases accountable for millions of deaths yearly across the globe – droplet or aerosol being the mode of transmission. Apart from the peculiar microbial physiology and drug efflux pumps with drug modifying enzymes that make Mtb impervious to the existing drug regimen recommended by the WHO via DOTS, lack of social awareness and misuse or mismanagement of drugs make it even more deadlier transforming Mtb to MDR-TB & XDR-TB, thus increasing the number of TB cases globally per annum. Amidst the dire need to combat the rising cases of drug-resistant TB, this article discusses the potential use of phytochemical derived efflux pump inhibitors (EPIs) and immunotherapy to fight TB with a brief insight into the molecular mechanism and structure of drug-efflux pumps found in Mtb. \u0000Keywords: Mycobacterium tuberculosis, efflux pumps, DOTS, efflux pump inhibitors (EPIs), immunotherapy.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"149 1","pages":"1306-1319"},"PeriodicalIF":0.0,"publicationDate":"2020-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78037047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nurses’ Organizational Citizenship Behavior and Its Association to their Job Satisfaction","authors":"Ashwaq T. Al-Ahmadi, S. Mahran, A. Rajab","doi":"10.15520/ijmhs.v10i10.3116","DOIUrl":"https://doi.org/10.15520/ijmhs.v10i10.3116","url":null,"abstract":"Objective: To identify the level of organizational citizenship behavior and its relation tojob satisfaction in the nursing field.Methodology: One step search strategy includes an extended search in various databases:Cumulative Index Nursing and Allied Health Literature (CINAHL), MEDLINE, ProQuest,and google scholar. Twenty published studied between January 2015 and April 2020 wereincluded in the review.Results: Two themes emerged from the present review, which are nurses' organizationalcitizenship behavior level and effect of nurses’ job satisfaction on organizationalcitizenship behavior. In the theme of nurses' organizational citizenship behavior level;seven studies found most nurses had a high level of OCB, three studies found they hadhigher than average, five studies demonstrated that they had a moderate level while onlyone study found their OCB on a low level. Regarding the other theme, three studies did notfind a correlation between job satisfaction and OCB, whereas three studies displayed thatjob satisfaction had a positive effect on OCB.Conclusion: Most of the studies found that nurses had a high-level regard OCB.However, the result of studies regards the influence of job satisfaction on OCB wereambivalent.Keywords: organizational citizenship behavior, organizational behavior, job satisfaction,work satisfaction, nurses.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80506894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The tumor suppressor gene TP53 and colorectal cancer: A review","authors":"S. Agrawal","doi":"10.15520/IJMHS.V10I09.3100","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I09.3100","url":null,"abstract":"TP53 is a gene and the p53 is its protein product. It is well known as a tumor suppressor gene, due to its inherent property of apoptosis and its role in the suppression of tumor formation. Its oncogenic property is due to p53 mutation. This oncogenic property is named “gain of oncogenic property”. The functions of p53 have been studied the world over, especially the oncogenic function. It is well known for its role to induce apoptosis, but now it is established that it is also a key player in cell cycle regulation. It controls and monitors the cell division, chromosomal segregation, and cellular senescence. Due to all these important cellular functions, this protein is labeled as the “guardian of the genome”. The p53 protein is a nuclear phosphoprotein. It is composed of 393 amino acids. The structural and functional domains are an N-terminal transactivation domain, a protein-rich regulatory domain, and a C-terminal domain involved in the regulation of DNA binding. The colorectal cancers (CRC) are a major cause of morbidity and mortality world over. This is the third most common cancer worldwide and the fourth most common cause of death. Although it is slow-growing cancer the five-year survival is low. It is a heterogeneous disease and is due to, a complex genetic and biochemical interplay. This review summarizes the functions of p53 and its role in CRC.   \u0000Keywords: TP53, p53, colorectal cancers, CRC, Tumor suppressor gene, apoptosis, cellular senescence, guardian of the genome.","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78330167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CASE REPORT ON BULLOUS PEMPHIGOID: A FATAL SKIN CONDITION","authors":"Punam Kela, Atharva Nanday, U. Desai","doi":"10.15520/IJMHS.V10I09.3097","DOIUrl":"https://doi.org/10.15520/IJMHS.V10I09.3097","url":null,"abstract":"Bullous pemphigoid (BP) is a fatal skin condition which is manifested as diffuse eczematous, pruritic lesions which is afterwards; appear as tense blistering lesions filled with clear fluid which is commonly observed in elderly. Direct immunofluorescence is used as the definitive standard for the diagnosis of BP. Line of treatment for BP includes drugs which are anti-inflammatory such as topical steroids and sulfonamides; second line of treatment includes the immune-suppressant agents such as azathioprine, systemic steroids and last line of therapy includes the agent which increases the elimination of abnormal antibodies from plasma. These may include the treatment options such as plasmapheresis and intravenous immunoglobulin. \u0000Key Words \u0000Bullous Pemphigoid, Autoimmune disease, Skin conditions","PeriodicalId":13590,"journal":{"name":"Innovative Journal of Medical and Health Science","volume":"2007 1","pages":"1253-1255"},"PeriodicalIF":0.0,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82484579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}