Industrial Crops and Products最新文献

{"title":"Onosma obtusifolia extracts: Antioxidant potential and molecular docking insights into acetylcholinesterase, α-amylase, and tyrosinase inhibition","authors":"Abdulmetin Hartavi","doi":"10.1016/j.indcrop.2025.121387","DOIUrl":"10.1016/j.indcrop.2025.121387","url":null,"abstract":"<div><div>Natural products provide bioactive compounds against oxidative stress and enzyme-related disorders. This study investigates the chemical composition, antioxidant properties, and enzyme inhibitory activities of <em>Onosma obtusifolia</em> extracts obtained via maceration (MAC-ME), ultrasound-assisted extraction (UAE-ME), and Soxhlet extraction (SOE-ME). Molecular docking was employed to evaluate interactions of major phytochemicals with target enzymes. Among the extracts, SOE-ME exhibited the highest total phenolic (36.42 mg GAEs/g) and flavonoid (34.85 mg REs/g) contents. Chlorogenic acid was the most abundant phenolic compound (8355 μg/g in MAC-ME), followed by rosmarinic acid and luteolin 7-glucoside. SOE-ME showed the strongest antioxidant activity, with IC₅₀ values of 1.29 mg/mL (DPPH) and 1.18 mg/mL (ABTS), as well as the most potent inhibition of acetylcholinesterase (IC₅₀: 1.25 mg/mL) and tyrosinase (IC₅₀: 1.82 mg/mL). Molecular docking highlighted rosmarinic acid as a key ligand, exhibiting strong binding affinities with acetylcholinesterase (ΔG: –9.48 kcal/mol), α-amylase (ΔG: –8.72 kcal/mol), and tyrosinase (ΔG: –8.12 kcal/mol). These findings indicate that <em>O. obtusifolia</em>, especially SOE-ME, may serve as a valuable source of antioxidant and enzyme-inhibitory agents. Further in vivo studies are encouraged to validate its pharmacological potential.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121387"},"PeriodicalIF":5.6,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable poly(vinyl alcohol)/chitosan electrospun nanofibers and casted films with bioactive additives – comparative study on physicochemical properties and in vitro biological activity","authors":"Julia Kulczyńska ,&nbsp;Vadym Chibrikov ,&nbsp;Dominika Pawcenis ,&nbsp;Roman J. Jędrzejczyk ,&nbsp;Victor Sebastian ,&nbsp;Justyna Cybulska ,&nbsp;Artur Zdunek ,&nbsp;Agnieszka Kyzioł","doi":"10.1016/j.indcrop.2025.121335","DOIUrl":"10.1016/j.indcrop.2025.121335","url":null,"abstract":"<div><div>Chitosan is a biocompatible and biodegradable polysaccharide with a plethora of biomedical and food applications. Its functionalization with additional biopolymers and bioadditives allows to modify its antimicrobial, mechanical and tribological properties, as well as cell proliferation. Thus, the aim of this study was to investigate the physicochemical properties and <em>in vitro</em> biological activity of poly(vinyl alcohol)/chitosan electrospun nanofibers and casted films with an addition of <em>Rosa damascena</em> and <em>Rosa rugosa</em> extracts, as well as gold nanoparticles. Poly(vinyl alcohol)/chitosan nanofibers and films were both electrospun and dry-casted with morphology, wettability, mechanical, thermal, antimicrobial properties, as well as cytotoxicity being examined. Specific attention has been drawn to the methodological approach on nanofiber electrospinning. Results showed data variabilities in wettability, mechanical and thermal properties were a matter of material fabrication technique, while those of swelling ability and degradation related to material composition. Antimicrobial activity, as well as lack of significant cytotoxicity were observed for both poly(vinyl alcohol)/chitosan nanofibers and films with an addition of rose extracts, as well as gold nanoparticles. Results reported in this study suggested poly(vinyl alcohol)/chitosan nanofibers and films with the investigated additives as promising biocompatible biomaterials with potential applications suggested such as external drug delivery in wound healing, topical therapies, biodegradable packings.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121335"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144313264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative multi-omics profiling of geographical and organ-specific variations of bioactive constituents in Andrographis paniculata: UHPLC-QTOF-MS, MALDI-MSI and antioxidant activity","authors":"Yun-Jie Liu ,&nbsp;Jia-Yi Zhang ,&nbsp;Xiao-Die Zhao ,&nbsp;Si-Qi Ma ,&nbsp;Kang Wang ,&nbsp;Ju-Tao Wang ,&nbsp;Jin-Song Liu ,&nbsp;Yang Yu","doi":"10.1016/j.indcrop.2025.121369","DOIUrl":"10.1016/j.indcrop.2025.121369","url":null,"abstract":"<div><div><em>Andrographis paniculata</em>, a medicinal economic value of crops, is extensively cultivated across subtropical regions of India and China, which contains <em>ent</em>-Labdane diterpenoid lactones (<em>ent</em>-LDLs) represented by andrographolide (AD) as its core bioactive components responsible for anti-inflammatory, antimicrobial, and antioxidant activities. However, significant geographical variations in these components have led to inconsistent quality standards across regions, presenting challenges in overall quality control. This study comprehensively elucidated the distribution patterns and metabolic variations of core <em>ent</em>-LDLs in different geographical origins and organ tissues of <em>A. paniculata</em> through integrated UHPLC-QTOF-MS-GNPS analysis, MALDI-MSI, and chemometrics/machine learning approaches. Eight key differential <em>ent</em>-LDLs dominated by andrographolide (AD) and its derivatives were identified across geographical regions, with isoandrographolide (IAD, 14-hydroxyl epimer of andrographolide) being incorporated for the first time. Notably, we firstly discovered that the root tissue predominantly accumulates IAD rather than AD as its major <em>ent</em>-LDLs, preliminarily revealing tissue-specific metabolic accumulation patterns of bioactive <em>ent</em>-LDLs. Meanwhile, qRT-PCR analysis also confirmed the differential expression of <em>ent</em>-LDLs -associated genes (<em>CPS2</em>, <em>GGPS</em>, <em>CPR2</em>, <em>CPR4</em>, <em>CYP71</em> and <em>DXS1</em>) in the roots, stems, and leaves. Furthermore, in <em>vitro</em> intervention studies using a pneumonia model demonstrated that these differential <em>ent</em>-LDLs alleviate LPS-induced pulmonary oxidative stress by suppressing ferroptosis in HPMEC cells through the Keap1-Nrf2/HO-1 pathway. These findings provide scientific evidence for quality improvement of <em>A. paniculata</em> and its potential high-value applications in pharmaceutical sectors for pneumonia prevention.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121369"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced production of novel bioactive metabolites in mung bean (Vigna radiata (L.) R. Wilczek) plants induced by signal molecule ethylene in a vertical farm","authors":"Du Yong Cho ,&nbsp;Se Hyeon Jeon ,&nbsp;Mu Yeun Jang ,&nbsp;Eun Jeong Ko ,&nbsp;Hee Yul Lee ,&nbsp;Jong Bin Jeong ,&nbsp;Ga Yong Lee ,&nbsp;Ki-Ho Son ,&nbsp;Md. Azizul Haque ,&nbsp;Jin Hwan Lee ,&nbsp;Kye Man Cho","doi":"10.1016/j.indcrop.2025.121382","DOIUrl":"10.1016/j.indcrop.2025.121382","url":null,"abstract":"<div><div>In the biofunctional material industry, enhancing bioactive metabolites in plants using signal stimulants is an emerging strategy. This study investigated the changes in bioactive metabolite content in different organs of mung bean plants treated with ethylene (ETL) in a closed chamber. In addition, we also examined its biomass, novel compounds, biological activities, and DNA protection. Through this approach, a practical method for producing mung bean plants with enhanced bioactive metabolites was proposed. ETL treatments led to a notable reduction in biomass, particularly in the leaves and roots, without affecting plant height. ETL treated leaves exhibited significant increases in the total phenolic, flavonoid, isoflavone, and flavone contents. Four compounds were identified in the mung bean organs following ETL treatment: 2′-hydroxydaidzein-4′,7-<em>O</em>-diglucoside, daidzein-4′,7-<em>O</em>-diglucoside, 2′-hydroxydaidzin, and 2′-hydroxydaidzein. Among these isoflavones, 2′-hydroxydaidzin and daidzin showed the highest significant accumulation levels in ETL treated leaves. In particular, the contents of 2′-hydroxydaidzin, daidzin, and genistin in the ETL treated leaves was increased by 77.4-fold (273.24–21,159.88 μg/g), 74.2-fold (429.67–31,845.13 μg/g), and 12.0-fold (268.35–3209.12 μg/g) respectively, compared with their contents in untreated leaves. Furthermore, the total phenolic and flavonoid contents increased from 13.87–24.59 and from 9.89 to 12.87 mg/g, respectively. These enhanced active metabolites in ETL treated mung bean organs significantly improved the antioxidant capacity, including radical scavenging, digestive enzyme-inhibition, and DNA protection activities. These findings underscore the potential of ETL as an effective elicitor and enhancer of bioactive metabolite production, supporting its application in high value functional bioresources.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121382"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haplotype-resolved genome assembly of Rosa laevigata reveals molecular mechanisms of secondary metabolite synthesis and adaptation evolution","authors":"Tao Yuan ,&nbsp;Jiao Chen ,&nbsp;Yuemei Zhao ,&nbsp;Guiyu Zhang ,&nbsp;Xiaoman Gao ,&nbsp;Yu Wu ,&nbsp;Niyan Xiang ,&nbsp;Xing Liu ,&nbsp;Rongxiang Zhang","doi":"10.1016/j.indcrop.2025.121351","DOIUrl":"10.1016/j.indcrop.2025.121351","url":null,"abstract":"<div><div><em>Rosa laevigata</em> is a valuable edible plant and traditional herbal medicine in China, renowned for its potent antioxidant and anti-inflammatory properties, as well as its therapeutic efficacy in treating urinary system disorders. Its remarkable adaptability to karst environments and high resistance to aphids further position it as an exceptional rose germplasm resource and a promising candidate for rocky desertification management in karst regions. However, the absence of a high-quality genome has limited a comprehensive understanding of its medicinal compound biosynthesis and environmental adaptation mechanisms. In this study, we successfully assembled two haplotype genomes of <em>R. laevigata</em>, the size of the two haplotype genomes were 493 Mb and 479 Mb, and the N50 was 49.5 Mb and 64.9 Mb, respectively. 43480 and 41251 protein-coding genes were annotated, respectively, with BUSCO assessments of 98.6 and 98.7. Comparative genomic analyses revealed recent proximal and tandem duplication events, which contributed to the expansion of gene families associated with terpenoid biosynthesis, anthocyanin biosynthesis, and glutathione metabolism. These expansions may have led to the population expansion of golden cherry since the Pleistocene as well as the adaptation to high radiation karst environments. We identified 249 positively selected genes, primarily enriched in metabolic pathways such as vitamin B6 metabolism, glutathione metabolism, and ascorbate and aldarate metabolism. Meanwhile, the gene families associated ascorbate and aldolate metabolism were significantly amplified. Additionally, we identified four calcium regulation-related genes (<em>MHX</em>, <em>NCL</em>, <em>CBL8</em>, and <em>PAO</em>) positively selected in early karst-distributed species. Protein-protein interaction analysis revealed direct and indirect interactions between MHX and proteins such as NCL, CCX, CAX, and MRS, The CBL8 proteins of <em>R. laevigata</em> have a higher calyx Ca^2 + binding capacity compared to those of Arabidopsis thaliana. This suggesting their potential roles in the adaptation of karst-distributed species to high-calcium environments. In summary, this study provides profound insights into the genomic evolution, metabolite biosynthesis, and environmental adaptation mechanisms of <em>R. laevigata</em>. It also establishes a robust foundation for future functional genomic research, including germplasm conservation and breeding studies.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121351"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of a thermosensitive nanoemulsion hydrogel loaded with Schizonepeta annua essential oil for enhanced wound healing","authors":"Cheng Feng ,&nbsp;Wang Xin ,&nbsp;Abula Reyanggu ,&nbsp;Ma Xueping ,&nbsp;Numonov Sodik ,&nbsp;Wu Tao ,&nbsp;Mahinur Bakri ,&nbsp;Maiwulanjiang Maitinuer","doi":"10.1016/j.indcrop.2025.121371","DOIUrl":"10.1016/j.indcrop.2025.121371","url":null,"abstract":"<div><div>Chronic wounds present a major global healthcare challenge, with bacterial infections significantly impeding healing processes and increasing treatment costs. This study addresses the critical need for multifunctional wound dressings by developing a novel thermosensitive hydrogel incorporating <em>Schizonepeta annua</em> essential oil nanoemulsions (SEO-NE-TG). We hypothesized that this formulation would provide both controlled antimicrobial protection and enhanced tissue regeneration capabilities. Through systematic optimization, we formulated a stable oil-in-water nanoemulsion using Tween-80, achieving uniform nanoparticles (10–20 nm) confirmed by TEM and DLS analysis. The resulting hydrogel demonstrated ideal properties for wound applications, including temperature-responsive gelation (transition at 15.7℃), favorable shear-thinning behavior, and erosion-controlled release of bioactive terpenes. The SEO-NE-TG maintained antimicrobial efficacy against critical wound pathogens including MRSA (MIC 3906 <em>μ</em>g/mL), while significantly accelerating wound healing in a rat burn model. Cytotoxicity studies with HaCaT keratinocytes revealed that SEO-NE maintained good biocompatibility at antimicrobial effective concentrations. Treatment resulted in 35 % higher wound contraction rate, enhanced epidermal regeneration, improved collagen organization, and significantly modulated inflammatory markers (IL-6, TGF-<em>β</em>, VEGF) compared to controls. These findings establish SEO-NE-TG as a promising platform for advanced wound management, offering a natural alternative to conventional antimicrobial dressings with superior healing promotion capabilities.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121371"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of key aroma components responsive for jasmine-like aroma in ‘Chungui’ cultivar oolong tea processing","authors":"Yongheng Zhang ,&nbsp;Ruiyang Shan ,&nbsp;Changqing Ding ,&nbsp;Xiaomei You ,&nbsp;Shiqin Zheng ,&nbsp;Zhihui Chen ,&nbsp;Xinlei Li ,&nbsp;Xiangrui Kong ,&nbsp;Yazhen Zhang ,&nbsp;Zhenghe Lin ,&nbsp;Xinchao Wang ,&nbsp;Changsong Chen","doi":"10.1016/j.indcrop.2025.121376","DOIUrl":"10.1016/j.indcrop.2025.121376","url":null,"abstract":"<div><div>The oolong tea produced from the <em>Camellia sinenesis</em> cultivar ‘Chungui’ (CG) is characterized by its distinctive and appealing jasmine-like floral aroma. However, the specific odorants contributing to this aroma and their changes during processing are not fully understood. This study investigated the changes in volatile compounds during CG oolong tea manufacturing, using the ‘Huangdan’ (HD) cultivar serving as a reference. A total of 536 volatiles were identified throughout the processing stages. Critical floral and fruity volatile compounds exhibited similar accumulation trends during the shaking and setting stages but diverged during fixing, rolling, and drying, resulting in distinct aroma attributes in the final CG and HD teas. Sensory evaluation and aroma analysis revealed that indole, (<em>E</em>)-β-ocimene, (<em>E</em>)-β-terpinolene, and benzeneacetaldehyde may synergistically contribute to the jasmine-like aroma of CG. These findings offer valuable insights into aroma development and changes during CG oolong tea processing, aiding in quality improvement through process optimization.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121376"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rugulopteryx okamurae: Effect of microwave pretreatment on PHB fermentation","authors":"Agustín Romero-Vargas,&nbsp;Pedro Fernández-Medina,&nbsp;Ana Blandino,&nbsp;Carlos J. Álvarez-Gallego,&nbsp;Manuel J. Díaz","doi":"10.1016/j.indcrop.2025.121373","DOIUrl":"10.1016/j.indcrop.2025.121373","url":null,"abstract":"<div><div>Polyhydroxyalkanoates (PHA) are biodegradable and sustainable bioplastics that are a promising alternative to conventional petrochemical-based plastics and contribute significantly to the reduction of environmental pollution. This study investigates the potential of using the invasive macroalga <em>Rugulopteryx okamurae</em> as a feedstock for PHA production, specifically polyhydroxybutyrate (PHB), through fermentation with <em>Cupriavidus necator</em>. The macroalga was pretreated using microwave-assisted extraction at different temperature conditions, followed by enzymatic hydrolysis to enhance the release of fermentable sugars and subsequent PHB production. Results indicate that microwave pretreatment at 160 °C yielded the highest growth of <em>C. necator</em> (CDW = 1.75 g·L⁻¹). However, pretreatment at higher temperatures (180 °C and 220 °C) led to reduced yields, probably due to the release of biological inhibitors. Additionally, the hydrolysate medium´s carbon-to-nitrogen (C/N) ratio was analysed, revealing that a lower C/N ratio, which was obtained in the hydrolysates from pretreated macroalgae, favoured bacterial growth. Higher C/N ratios obtained in the hydrolysate from non-pre-treated macroalgae were more conducive to PHB production, achieving the highest PHB accumulation (94 %). The study demonstrated that non-pretreated <em>R. okamurae</em> biomass led to the highest PHB accumulation, surpassing yields from other pretreatment methods like solid-state fermentation or hydrothermal acid pretreatment. This research highlights the potential of using <em>R. okamurae</em>, an underutilized and invasive macroalga, as a renewable resource for PHA production, offering a sustainable alternative to conventional plastics and addressing environmental challenges such as beach-cast biomass accumulation. Future studies could focus on optimizing pretreatment processes and exploring more efficient ways to convert macroalgae biomass into bioplastics.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121373"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the unique UV-thermo-oxidative resistance characteristics of natural rubber induced by non-rubber components","authors":"Meng-Zhen Zhou,&nbsp;Lin Chen,&nbsp;Jing Zhang,&nbsp;Xing Guo,&nbsp;Lai-Fu Yuan,&nbsp;Shuangquan Liao,&nbsp;Yan-Chan Wei","doi":"10.1016/j.indcrop.2025.121370","DOIUrl":"10.1016/j.indcrop.2025.121370","url":null,"abstract":"<div><div>Diene rubbers are prone to aging due to their unsaturated structure, a key factor limiting their industrial applications. Nevertheless, although natural rubber (NR) and synthetic <em>cis</em>-polyisoprene (PI) are both diene rubbers with similar molecular chain structures, NR exhibits markedly superior aging resistance compared to PI. In our recent studies, we found that removing non-rubber components (NRCs) results in a 4.68-fold (from 58.10 % to 12.42 %) decrease in the retention of mechanical properties in NR samples after 96 h of UV-thermo-oxidative aging, confirming that NRCs contribute to NR's excellent aging resistance. To elucidate the underlying mechanism from the molecular level, we analyzed the evolution of the crosslinking network in NR with different NRCs content using FTIR and XPS, and monitored free radical dynamics through EPR. The results demonstrate that NRCs improve aging resistance by modifying crosslinking bond types, inhibiting network degradation, and scavenging free radicals to suppress chain scission reactions. Interestingly, by incorporating acetone extract (AE) and its key antioxidant component <em>α</em>-tocopherol into PI, the superior UV-thermo-oxidative resistance of NR is effectively replicated in synthetic rubber. By incorporating AE, the mechanical properties retention of PI improved by 2.30-fold after 72 h of aging. Furthermore, the addition of 1.0phr <em>α</em>-tocopherol enhances the tensile strength retention of PI from 45.77 % (9.37 MPa) to 69.89 % (14.30 MPa) after 48 h of aging, indicating its significant contribution to improving UV-thermo-oxidative resistance. This work not only provides innovative strategies for designing biomimetic rubbers but also proposes a green and sustainable strategy for enhancing the durability of diene rubbers.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121370"},"PeriodicalIF":5.6,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144321610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioinspired green degradable tannic acid-gelatin sponges for rapid hemostasis and wound repair","authors":"Dian Yu ,&nbsp;Yujia Li ,&nbsp;Fengyong Wang ,&nbsp;Shengyu Li ,&nbsp;Jingwei Wang ,&nbsp;Yicheng Wang ,&nbsp;Wenjun Xu ,&nbsp;Xianghou Zhen ,&nbsp;Jin Wu ,&nbsp;Haorui Zha ,&nbsp;Jintao Fang ,&nbsp;Wei Zhang","doi":"10.1016/j.indcrop.2025.121358","DOIUrl":"10.1016/j.indcrop.2025.121358","url":null,"abstract":"<div><div>Uncontrolled bleeding is associated with a higher risk of death, particularly during military conflicts, traffic accidents, and surgeries. In this study, an effective one-pot method for preparing a green biodegradable hemostatic sponge (TA@Gel) without any polymerization was developed by combining gelatin and tannic acid, two common natural materials. The hemostatic sponge was characterized using scanning electron microscope (SEM), thermogravimetry (TG), X-ray photoelectron spectroscopy (XRD), X-photoelectron spectroscopy (XPS), energy-dispersive X-ray spectroscopy (EDS), and ultraviolet radiation (UV), before their commercial prospects were demonstrated using three separate animal models. Interestingly, TA5@Gel hemostatic sponges exhibited better and faster hemostatic performance than current hemostat options in vitro and in vivo. Exploration of their hemostatic mechanisms showed that the TA5@Gel sponges significantly promoted blood coagulation by rapidly aggregating blood components, activating platelets and coagulation cascade. Besides being efficient in hemostasis, TA5@Gel could also be used for effective repair of cutaneous wounds owing to its biodegradability, excellent cytocompatibility, antioxidant activity and adhesion ability. Therefore, the TA5@Gel sponge has considerable potential for practical application in clinical settings.</div></div>","PeriodicalId":13581,"journal":{"name":"Industrial Crops and Products","volume":"233 ","pages":"Article 121358"},"PeriodicalIF":5.6,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144314344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}