Indian journal of cancer最新文献_第2页

Primary pulmonary paraganglioma: Report of two cases with one case showing cytokeratin positivity. 原发性肺副神经节瘤：2例报告，1例细胞角蛋白阳性。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_902_21

Sunil Pasricha, Ankur Kumar, Ankush Jajodia, Laleng Darlong, Anurag Mehta

{"title":"Primary pulmonary paraganglioma: Report of two cases with one case showing cytokeratin positivity.","authors":"Sunil Pasricha, Ankur Kumar, Ankush Jajodia, Laleng Darlong, Anurag Mehta","doi":"10.4103/ijc.ijc_902_21","DOIUrl":"10.4103/ijc.ijc_902_21","url":null,"abstract":"Abstract: Primary pulmonary paraganglioma (PPP) is a rare tumor, with few cases described in the literature. Here, we report two cases of PPP, one of which shows cytokeratin (CK) positivity, along with a literature review. In the first case, a 76-year-old male patient presented with a right-lung peribronchial mass, while in the second case, a 53-year-old male, presented with a right middle lobe mass. In both cases, the guided biopsy revealed a similar morphology comprising a tumor with polygonal cells in a back-to-back nested pattern, showing strong immunoexpression with synaptophysin and chromogranin. In the first case, a heterogenous immunoexpression of CK was observed, which was an unusual finding. In small biopsy specimens, PPPs with an aberrant CK expression can be misdiagnosed as pulmonary carcinoids or non-small cell lung carcinoma, which have distinct prognostic and therapeutic implications. Both cases underwent lobectomy, and the findings were confirmed on the resection specimen. The presented cases highlight the role of diligent histomorphological examination, coupled with clinico-radiological input and a judicious immunohistochemistry panel, to avoid erroneous interpretation and management.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"320-323"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concerns of cancer patients and their caregivers in a palliative care clinic. 姑息治疗诊所中癌症患者及其护理人员的关注点。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_351_23

Vrinda Singla, Minni Arora, Ravi T Miriyala, Bhavana Rai, G Y Srinivas, Nagarjun Ballari, Treshita Dey, Sushmita Ghoshal

{"title":"Concerns of cancer patients and their caregivers in a palliative care clinic.","authors":"Vrinda Singla, Minni Arora, Ravi T Miriyala, Bhavana Rai, G Y Srinivas, Nagarjun Ballari, Treshita Dey, Sushmita Ghoshal","doi":"10.4103/ijc.ijc_351_23","DOIUrl":"10.4103/ijc.ijc_351_23","url":null,"abstract":"Background: In busy tertiary care centers, although the physical symptoms of patients are well-addressed, the psychosocial concerns, and needs of patients and their caregivers are often overlooked. The study aimed to assess the concerns of patients with advanced cancers and their caregivers on the day of referral to the palliative care clinic.Methods: A survey was conducted on 140 subjects of advanced malignancies attending the palliative care clinic. These included 70 patients along with their caregivers. The patients were assessed for their psychosocial concerns and their information needs on their first visit to the palliative care clinic.Results: The concerns of both the patients and the caregivers were separately documented. Pain followed by fatigue and insomnia were the most bothersome symptoms reported by the patients. While most of the patients (91.4%) wanted symptom relief, the patient's life expectancy was a major concern of the caregivers. The other common concerns of the patients were the disease status and curability of the disease whereas the caregivers were more concerned about the alternative treatment measures. Of the psychosocial problems, the majority of them were related to financial concerns followed by settlement of children and loneliness.Conclusion: A difference between the needs of patients and their caregivers was observed in the present study. This may be attributed to less focus on the psychosocial problems in the busy outpatient clinics. Psychosocial concerns and effective communication both with the patient and their caregivers are required to ensure holistic care.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"242-247"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic values of the monocyte to hemoglobin ratio and neutrophil-lymphocyte ratio to albumin ratio in non-small cell lung cancer. 单核细胞与血红蛋白比值和中性淋巴细胞与白蛋白比值在非小细胞肺癌中的诊断价值。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_241_23

Si-Ting Zhao, Fen-Hong Qian

引用次数: 0

Addressing the unseen burden in cancer care - Distress and treatment compliance. 解决癌症护理中看不见的负担——困扰和治疗依从性。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_6_25

Adwaita Gore, Uma Dangi

引用次数: 0

Multidimensional analysis of rectal cancer: Clinicodemography, patterns of care and failure - Single institutional ambispective study I. 直肠癌的多维分析：临床人口学、治疗模式和失败——单一机构的双视角研究1。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_395_23

Shaqul Qamar Wani, Talib Khan, Saiful Yamin Wani, Aijaz Khan, Shahida Nasreen

{"title":"Multidimensional analysis of rectal cancer: Clinicodemography, patterns of care and failure - Single institutional ambispective study I.","authors":"Shaqul Qamar Wani, Talib Khan, Saiful Yamin Wani, Aijaz Khan, Shahida Nasreen","doi":"10.4103/ijc.ijc_395_23","DOIUrl":"10.4103/ijc.ijc_395_23","url":null,"abstract":"Introduction: Colorectal cancers (CRC) being the third most commonly diagnosed cancer worldwide. Although newer drugs, advanced surgical and radiation techniques have revolutionized the treatment of rectal cancers, cure rates are still less because of the frequent locoregional and distant failures.Materials and methods: This ambispective study was conducted at a university teaching and tertiary care referral hospital. The data of the patients were collected from the patient records without the active participation of the patients. The data were collected with regard to demographics, clinical presentation, treatment received, and patterns of failure.Results: Rural patients were in majority, Male patients were dominant in number, Married patients were more compared to unmarried patients, Smokers outnumbered never-smokers, Mean age at presentation was 52 years, Neoadjuvant treatment was received by 22% of patients, Curative surgical resection was done in 62% of patients, Palliative treatment was received by 25% of patients. No recurrence was seen in 43.01% (n=151) of patients, while locoregional recurrence, distant recurrence (metastasis) or both were reported in 20.80% (n=73), 10% (n=35) and 8.53% (n=30) respectively. Disease progression was seen in 11.39% (n=40).Conclusions: This study highlights the demographic profile, clinical presentation, smoking habits, marital status, treatment patterns, types of curative surgeries, male-female ratio, rural-urban distribution, mean age of presentation, and patterns of failure.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"248-256"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum: A retrospective analysis of 26 cases of duodenal neuroendocrine tumor treated by endoscopic submucosal dissection. 误：回顾性分析内镜下粘膜下剥离术治疗十二指肠神经内分泌肿瘤26例。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_7_25

引用次数: 0

Primary pure angiosarcoma of the ovary: A case report. 卵巢原发性纯血管肉瘤1例。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_782_21

Ankur Kumar, Anila Sharma, Meenakshi Kamboj, Tanu Agrawal

引用次数: 0

IPD regimen effect on the levels of VEGF and IL-6 in elderly patients with recurrent multiple myeloma. IPD方案对老年复发性多发性骨髓瘤患者VEGF和IL-6水平的影响

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_51_24

Huiying Zhao, Shengyu Ma, Wan Li

{"title":"IPD regimen effect on the levels of VEGF and IL-6 in elderly patients with recurrent multiple myeloma.","authors":"Huiying Zhao, Shengyu Ma, Wan Li","doi":"10.4103/ijc.ijc_51_24","DOIUrl":"10.4103/ijc.ijc_51_24","url":null,"abstract":"Background: To investigate IPD regimen effect on vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) levels in elderly patients with recurrent multiple myeloma (MM).Methods: Eighty-two elderly patients with relapsed multiple myeloma in our hospital from January 2019 to December 2021 were selected and randomly divided into TD group and IPD group, 41 cases in each group. The TD group was treated with thalidomide + dexamethasone, while the IPD group was treated with ixazomib + pomalidomide + dexamethasone. The treatment effect and the changes of VEGF and IL-6, TNF-α, levels before treatment, 6 months, and 12 months after treatment were compared by the log-rank test. The Kaplan-Meier method determined the progression-free survival (PFS) of patients.Results: The clinical efficacy distribution of IPD was better than that of the TD group (Z = 2.407, P = 0.016). No significant difference was showed in serum VEGF and IL-6, TNF-α, concentrations before treatment (T0) (P > 0.05). The serum concentrations of VEGF and IL-6, TNF-α, in the IPD group were lower at 6 months and 12 months after treatment. The incidence of progression in the IPD group was 9.76% (4/41), and the estimated time of no progression was 11.73 ± 0.21 months. The incidence of progression was 19.51% (8/41) in the TD group, and the estimated time without progression was 10.95 ± 0.38 months, showing no significant difference (χ2 = 1.718, P = 0.190).Conclusion: IPD regimen for relapsed elderly multiple myeloma has the characteristics of improving clinical efficacy and inhibiting VEGF and IL-6, TNF-α, concentrations increase. However, compared with TD therapy, IPD regimen has similar effects on the risk and time of progression.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"203-208"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Which surgery for breast cancer after neoadjuvant chemotherapy. 乳腺癌新辅助化疗后的手术。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_131_23

Pelin Altınok, Ayşe Altınok, Selman Emiroğlu, Mahmut Müslümanoğlu

{"title":"Which surgery for breast cancer after neoadjuvant chemotherapy.","authors":"Pelin Altınok, Ayşe Altınok, Selman Emiroğlu, Mahmut Müslümanoğlu","doi":"10.4103/ijc.ijc_131_23","DOIUrl":"10.4103/ijc.ijc_131_23","url":null,"abstract":"Background: Neoadjuvant chemotherapy (NAC) is the standard practice in locally advanced breast cancer cases and in some biological subtypes. There is still no consensus on whether breast-conserving surgery or mastectomy should be performed after NAC and there is no certain point about how the axilla should be approached. These problems stem from concerns about survival.Methods: We retrospectively evaluated the 10-year survival results of 251 patients who either had breast-conserving surgery (BCS) or mastectomy after NAC.Results: Better loco-regional control was achieved when pathologic axillary node positivity was below %50. Best disease-free (DFS) and overall survival (OS) results were obtained when the breast had a complete response after NAC regardless of axillary response. Clinic N2/3 tumors were negatively associated with DFS while cT3/4 were negatively associated with OS and multifocality was negatively associated with both.Conclusion: When BCS was performed, local recurrence rates were negatively affected in multifocal cases, but no adverse effects were found on survival of avoiding mastectomy in patients who became eligible for BCS.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"220-227"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical profile and outcome of pediatric synovial sarcoma - Eleven-year experience from a tertiary cancer center in LMIC. 儿童滑膜肉瘤的临床概况和预后——来自LMIC三级癌症中心的11年经验。

IF 1.1 4区医学

Indian journal of cancer Pub Date : 2025-04-01 Epub Date: 2025-08-08 DOI: 10.4103/ijc.ijc_668_22

Priyakumari Thankamony, Maharshi Trivedi, Manjusha Nair, Binitha Rajeswari, Guruprasad Chellappan Sojamani, Prasanth Varikkattu Rajendran, Kalasekhar Vijayasekharan, Rari Mony, Arun Sankar, Km Jagathnath Krishna

{"title":"Clinical profile and outcome of pediatric synovial sarcoma - Eleven-year experience from a tertiary cancer center in LMIC.","authors":"Priyakumari Thankamony, Maharshi Trivedi, Manjusha Nair, Binitha Rajeswari, Guruprasad Chellappan Sojamani, Prasanth Varikkattu Rajendran, Kalasekhar Vijayasekharan, Rari Mony, Arun Sankar, Km Jagathnath Krishna","doi":"10.4103/ijc.ijc_668_22","DOIUrl":"10.4103/ijc.ijc_668_22","url":null,"abstract":"Background: Synovial sarcoma (SS) is the most common non-rhabdomyosarcoma soft tissue sarcoma in children. Data regarding the outcome in children from developing countries are scarce. We analyzed the clinical characteristics and outcome of pediatric SS.Materials and methods: Children ≤14 years of age, diagnosed to have SS between January 1, 2007 and December 31, 2017 at a tertiary cancer center in India, were retrospectively analyzed. Details regarding clinical presentation and treatment were recorded, and the outcome was analyzed using Kaplan-Meier survival analysis.Results: Fourteen children were diagnosed with SS. The median age was 132 months (range 54-168 months), and the male:female ratio was 1.8:1. Group I, II, III, and IV disease was seen in four (28.6%), six (42.9%), three (21.4%), and one (7.1%) child, respectively. Extremity was the most common site of primary (n = 13, 92.8% children). Tumor size was ≤5 cm in nine (64.3%) children. The treatment modalities were surgery only (n = 2, 14.3%), surgery and radiation (n = 1, 7.1%), surgery and chemotherapy (n = 5, 35.7%), and surgery, radiation, and chemotherapy (n = 6, 42.9%). At a median follow-up of 62.5 months (range 18-125 months), the 4-year event-free survival (EFS) and the overall survival were 77.7% and 85.7%, respectively. The 4-year EFS for children with smaller tumors (≤5 cm) was 77.8%, compared to 60% for children with larger tumors. The 4-year EFS for male was 53.3%, compared to 100% for female patients.Conclusion: Our study demonstrates that good survival can be achieved in children with SS in low- and middle-income countries (LMICs) by appropriate utilization of the available resources judiciously. Smaller tumor size and female gender were associated with a better outcome.","PeriodicalId":13505,"journal":{"name":"Indian journal of cancer","volume":"62 2","pages":"195-202"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144821347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0