Indian Journal of Psychological Medicine最新文献

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Understanding Alcohol and Illicit Drug Use in Young College Students: A Qualitative Work from India Based on Social Norms Theory. 了解青年大学生使用酒精和非法药物的情况:基于社会规范理论的印度定性研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-10-01 DOI: 10.1177/02537176241283381
Abhishek Ghosh, Blessy B George, Jatina Vij, Renjith R Pillai, Kathirvel Soundappan, Mamta Sharma, Debasish Basu
{"title":"Understanding Alcohol and Illicit Drug Use in Young College Students: A Qualitative Work from India Based on Social Norms Theory.","authors":"Abhishek Ghosh, Blessy B George, Jatina Vij, Renjith R Pillai, Kathirvel Soundappan, Mamta Sharma, Debasish Basu","doi":"10.1177/02537176241283381","DOIUrl":"10.1177/02537176241283381","url":null,"abstract":"<p><strong>Background and objectives: </strong>Substance use among young college students in India poses public health challenges. This study seeks to uncover the motivation behind alcohol and illicit drug consumption, applying social norms theory.</p><p><strong>Methods: </strong>This qualitative research utilized the framework method to analyze data from 14 college students (18-24 years) across various disciplines. Participants were selected using purposive sampling to ensure diversity in demographics and perspectives. Data collection was conducted online. The study used a combination of in-depth interviews (n = 14) and focused group discussions (n = 2). We used AtLAS.ti to facilitate data analysis. We used a mixed inductive and deductive coding approach. A mind map was generated to visualize the complex interplay between social norms and other individual and external mediators.</p><p><strong>Results: </strong>We identified 10 themes, 20 subthemes, and 42 codes. The themes revealed descriptive (e.g., media and modernization) and injunctive (e.g., availability and legality) social norms that facilitate substance use and social disapproval and stigma that might deter young people from using substances. Family and institutional support were also found to play a protective role. The individuals also weigh the personal consequences (e.g., health and academic harm) and advantages (e.g., coping and relaxation) of substance use, which can influence their decision to use substances. Gendered norms and subtle differences in the social norms between alcohol and illicit drugs were also identified.</p><p><strong>Conclusion: </strong>Our study illuminates culturally tailored substance use prevention/intervention strategies that operate at the social, individual, and policy levels.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241283381"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hindi Translation, Cultural Adaptation, and Validation of Modified Weight Bias Internalization Scale (WBIS-M): A Cross-Sectional Study from the Metabolic Surgery Clinic in North India. 改良体重偏差内化量表(WBIS-M)的印地语翻译、文化适应和验证:印度北部代谢外科诊所的横断面研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-10-01 DOI: 10.1177/02537176241280109
Kumari Rina, Rosali Bhoi, Anubhav Vindal, Pawanindra Lal
{"title":"Hindi Translation, Cultural Adaptation, and Validation of Modified Weight Bias Internalization Scale (WBIS-M): A Cross-Sectional Study from the Metabolic Surgery Clinic in North India.","authors":"Kumari Rina, Rosali Bhoi, Anubhav Vindal, Pawanindra Lal","doi":"10.1177/02537176241280109","DOIUrl":"10.1177/02537176241280109","url":null,"abstract":"<p><strong>Background: </strong>The lack of culturally-sensitive tool masks the epidemiology of weight-bias and internalized-stigma. This study aimed to translate, adapt, and validate the Modified Weight-Bias Internalization Scale (WBIS-M) into Hindi.</p><p><strong>Methods: </strong>The translation and adaptation process followed the World Health Organization guidelines. Three psychiatrists translated the original WBIS-M into Hindi. The bilingual panel comprised four psychiatrists, two laparoscopic bariatric surgeons, a professor of English, and an individual with severe obesity (with an International English Language Testing System (IELTS) score of Band 8.5) who was familiar with Western culture. The panel identified and resolved inadequate expressions of translations or discrepancies. An independent translator, whose mother tongue was English, back-translated it into the English language. Focused group discussions with individuals with severe obesity were conducted. The final H-WBIS-M was administered to undergraduates (<i>n</i> = 120) after seven days. Test-retest reliability was assessed. The original WBIS-M, Eating Disorder Diagnostic Screen, and Fat Phobia Scale-Short Form were administered to 120 undergraduates and 55 individuals with severe obesity (<i>n</i> = 175)]. Reliability and validity of H-WBIS-M were analyzed.</p><p><strong>Results: </strong>Kaiser-Meyer-Olkin measure of sampling adequacy was 0.788, and Bartlett's test of sphericity was χ<sup>2</sup> = 1381.892, <i>p</i> = 0.000. The exploratory factor analysis extracted three components. Spearman-Brown coefficient for H-WBIS-M was 0.875. The internal consistency was α = 0.875 (<i>p</i> = 0.000), intraclass correlation coefficient was 0.857 (95% confidence interval [CI] = 0.812-0.893) (<i>p</i> = 0.000), and Pearson correlation ranged from 0.869 to 0.989 (<i>p</i> = 0.000). Cross-language concordance revealed a significant intraclass correlation coefficient (0.877-0.986) (<i>p</i> = 0.000) and Pearson correlation ranging from 0.781 to 0.972 (<i>p</i> = 0.000).</p><p><strong>Conclusions: </strong>The H-WBIS-M demonstrated good psychometric properties based on standard testing procedures.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241280109"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Narrative Review on the Impact of Teachers' Support in the Prevention of Death by Suicide Among Young People. 教师支持对预防青少年自杀死亡影响的叙述性评论。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-10-01 DOI: 10.1177/02537176241284061
Kallabi Borah, Tessy Treesa Jose, Anil Kumar Mysore Nagaraj, Linu Sara George
{"title":"A Narrative Review on the Impact of Teachers' Support in the Prevention of Death by Suicide Among Young People.","authors":"Kallabi Borah, Tessy Treesa Jose, Anil Kumar Mysore Nagaraj, Linu Sara George","doi":"10.1177/02537176241284061","DOIUrl":"10.1177/02537176241284061","url":null,"abstract":"<p><strong>Background: </strong>Death by suicide among young people is a growing issue worldwide. Every year, 46000 children (10-19 years old) take their lives. Lack of social support is one of the causes of suicide in young people. This narrative review aims to highlight the impact of teachers' support in the prevention of death by suicide among young people.</p><p><strong>Methods: </strong>A literature search was conducted in Scopus, PubMed, Embase, and Web of Science to find out the relevant studies using the keywords and synonyms of \"social support,\" \"young,\" \"suicide,\" and \"teacher.\" The original articles published in indexed and peer-reviewed English language journals in the last 10 years (2014-2023) were included in this review. The included articles were focused on teachers' support in terms of the prevention of suicide among young people.</p><p><strong>Results: </strong>After screening the title-abstract and full-text articles, the review findings revealed that support from teachers has a positive impact on the prevention of suicide among young people. Young people who have higher teachers' support show lower suicidal behaviors. Hence, teachers' support acts as a protective factor against suicide in young people.</p><p><strong>Conclusion: </strong>The review concludes that teachers' support has shown a positive impact on reducing suicidal behaviors among young people. Teachers are important sources of support in understanding suicidal behaviors in young people. Holistic support from each one of us is the enormous need to reduce the number of suicides. Studies have recommended that teachers' support should be the focus of intervention, for example, school-based psychoeducation on young people's suicide.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241284061"},"PeriodicalIF":1.9,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572342/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Knowledge, Attitude and Behaviors of Medical Students: A Cross-sectional Study. 医学生的性知识、态度和行为:横断面研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-30 DOI: 10.1177/02537176241275554
Sahil H Patel, Nimisha D Desai, Sandip H Shah
{"title":"Sexual Knowledge, Attitude and Behaviors of Medical Students: A Cross-sectional Study.","authors":"Sahil H Patel, Nimisha D Desai, Sandip H Shah","doi":"10.1177/02537176241275554","DOIUrl":"10.1177/02537176241275554","url":null,"abstract":"<p><strong>Introduction: </strong>Exposure to sexually explicit media influences the sexual knowledge, attitudes, and behavior of youth, so studying this among medical students is of utmost importance.</p><p><strong>Aim: </strong>To study sexual knowledge, attitudes, behaviors, and sources of influence among medical students.</p><p><strong>Methodology: </strong>A descriptive, cross-sectional, analytical, web-based study was conducted to assess sexual knowledge, attitudes, behaviors, and sources influencing sexuality in medical students via Google Forms. The form consisted of three parts: the first part was an information sheet and consent form, the second part included the participant's sociodemographic data and the third part related to two study tools, the Sexual Knowledge and Attitude Questionnaire-II (SKAQ-II) and the sexual behavior and sources of influence scale.</p><p><strong>Result: </strong>A total of 300/950 (31.5%) medical students responded to the Google questionnaire. Their mean age was 20.43 ± 1.87 years (range: 18-26 years). The mean score for sexual knowledge and attitude was 24.35 ± 4.93 and 23.79 ± 4.87, respectively, which suggested that they had good sexual knowledge and liberal attitudes toward sexuality with female preponderance. As student's academic year progresses, their sexual knowledge improves. There was a significant strong positive correlation between sexual attitude and knowledge with a Pearson correlation of r = 0.95, <i>P</i> = 0.004, which means the higher the knowledge, the better the attitude. Medical student's engagement in sexual behaviors with self- and others was at age 18.45 years. The internet was the major source for getting information related to sexual behaviors for them, but they relied on doctors and friends for guidance.</p><p><strong>Conclusion: </strong>Medical students had adequate sexual knowledge, which was the reason for their liberal attitude toward sexuality. Their major source of sexual knowledge was the internet, although they confided in doctors for sexual doubts.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241275554"},"PeriodicalIF":1.9,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Navigating Grief in the Realm of Patient Mortality: Insights from Trainee Doctors from a Tertiary Medical Hospital in India- A Qualitative Study. 在病人死亡的悲痛中前行:印度一家三级医疗医院实习医生的见解--一项定性研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-27 DOI: 10.1177/02537176241281904
Aishwarya R Katti, Akash R Nandanikar, Aditya Karthikeyan, Vyjayanthi Nittur Venkataramu, Mohan Raju Shankarappa, Murali Thyloth
{"title":"Navigating Grief in the Realm of Patient Mortality: Insights from Trainee Doctors from a Tertiary Medical Hospital in India- A Qualitative Study.","authors":"Aishwarya R Katti, Akash R Nandanikar, Aditya Karthikeyan, Vyjayanthi Nittur Venkataramu, Mohan Raju Shankarappa, Murali Thyloth","doi":"10.1177/02537176241281904","DOIUrl":"10.1177/02537176241281904","url":null,"abstract":"<p><strong>Background: </strong>Physician grief, as defined by Kenneth Doka as disenfranchised grief, refers to \"the grief that individuals experience when they incur a loss that is not openly acknowledged, publicly mourned, or socially supported.\" The experience of patient deaths on the emotional health of young doctors is unknown. The after-effects like stress, anxiety, burnout, depression, and others indirectly have a potential impact on decision-making and patient care. The study aims to shed light on this underexplored dimension and advocate for appropriate training and support to promote physician well-being.</p><p><strong>Methods: </strong>A qualitative study with a phenomenological approach was used to help explore the lived experience of trainee doctors confronted with patient deaths. The data collection was done through focused group discussions (FGDs) with three groups of trainee doctors. A semi-structured interview guide was framed and focused on their experiences of initial reactions, coping, reflections, and unmet needs among participants. Each interview was manually coded, organized into subthemes, and further into larger themes. All authors agreed upon themes and subthemes.</p><p><strong>Results: </strong>The findings are elaborated with necessary quotes taken from the transcripts of the FGDs. The main themes identified were (a) Losing a patient's emotions behind the screen, (b) Psychological and Environmental battles, and (c) Identifying lacunae and expressing unmet needs.</p><p><strong>Conclusion: </strong>The study findings were corroborated by concepts of disenfranchised grief, iatrogenic distress, emotionally unavailable doctors, and poor coping abilities. It also advocates for protocols and proactive measures to support interns and resident doctors.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241281904"},"PeriodicalIF":1.9,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Observational Case-control Study for BDNF Val66Met Polymorphism and Serum BDNF in Patients with Major Depressive Disorder (MDD). 重度抑郁障碍 (MDD) 患者 BDNF Val66Met 多态性与血清 BDNF 的病例对照观察研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-25 DOI: 10.1177/02537176241280050
Raja Babu Ramawat, Rizwana Quraishi, Raman Deep, Ram Kumar, Ashwani Kumar Mishra, Raka Jain
{"title":"An Observational Case-control Study for BDNF Val66Met Polymorphism and Serum BDNF in Patients with Major Depressive Disorder (MDD).","authors":"Raja Babu Ramawat, Rizwana Quraishi, Raman Deep, Ram Kumar, Ashwani Kumar Mishra, Raka Jain","doi":"10.1177/02537176241280050","DOIUrl":"10.1177/02537176241280050","url":null,"abstract":"<p><strong>Background: </strong>The brain-derived neurotrophic factor (BDNF) has an important role in the growth of neurons and synaptic transmission. The BDNF gene Val66Met polymorphism (G/A) is associated with depression, but findings have not been consistently replicated. This study adopts a case-control design with an aim to investigate the association of Val66Met polymorphism and peripheral BDNF (serum) levels in patients of major depressive disorder (MDD) and healthy individuals (controls).</p><p><strong>Materials and method: </strong>This study adopts an observational, case-control design with a total of 174 participants. Cases (n = 87) were currently depressed, having Diagnostic and Statistical Manual of Mental Disorders (DSM-5) MDD, without psychiatric comorbidity. Controls (n = 87) comprised healthy individuals with no family history of psychiatric illness. The cases were evaluated using the NIMH-Life Chart Method, Hamilton Depression Rating Scale (HAM-D), Clinically Useful Depression Outcome Scale (CUDOS), and Clinical Global Impression (CGI). TaqMan assay was used for genotyping, and serum BDNF was measured using Enzyme-linked immunosorbent assay (ELISA).</p><p><strong>Results: </strong>The case mean age was 35.32 ± 11.69 years (52% females) and comparable to controls. Allelic distribution was 33% (Met), and genotypic distribution was 17% (Met/Met), 32% (Val/Met), and 51% (Val/Val) for cases. The genotypic distribution did not differ across study groups. Serum BDNF was significantly lower in MDD cases as compared to controls (<i>p <</i> .001). The serum BDNF levels were comparable across the genotypic groups among cases.</p><p><strong>Conclusion: </strong>The Val66Met polymorphism has not been associated with a risk for MDD and, interestingly, did not influence the BDNF levels (serum). Significantly low BDNF levels were found in MDD cases. The study findings show that factors other than Val66Met gene polymorphism have a role in modulating serum BDNF levels.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241280050"},"PeriodicalIF":1.9,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropsychiatric Sequelae of Urbach- Wiethe Disease in Siblings: A Case Series. 兄弟姐妹乌巴-维特病的神经精神后遗症:病例系列。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-25 DOI: 10.1177/02537176241280018
Shweta Shukla, Aalapi Prajapati, Aatman Parikh, Yaksh Oza, Dhwani Parikh, Alpesh Gediya
{"title":"Neuropsychiatric Sequelae of Urbach- Wiethe Disease in Siblings: A Case Series.","authors":"Shweta Shukla, Aalapi Prajapati, Aatman Parikh, Yaksh Oza, Dhwani Parikh, Alpesh Gediya","doi":"10.1177/02537176241280018","DOIUrl":"10.1177/02537176241280018","url":null,"abstract":"","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241280018"},"PeriodicalIF":1.9,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental Health Issues and Psychosocial Contexts in CICL Children Versus Non-CICL Children: A Comparative Study. CICL 儿童与非 CICL 儿童的心理健康问题和社会心理环境:比较研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-25 DOI: 10.1177/02537176241279546
Fathima Hasanath K P, Prasad Kannekanti, Sanjay Kumar Munda, Alagarsami A R
{"title":"Mental Health Issues and Psychosocial Contexts in CICL Children Versus Non-CICL Children: A Comparative Study.","authors":"Fathima Hasanath K P, Prasad Kannekanti, Sanjay Kumar Munda, Alagarsami A R","doi":"10.1177/02537176241279546","DOIUrl":"10.1177/02537176241279546","url":null,"abstract":"<p><strong>Background: </strong>Children in conflict with law (CICL) is an emerging issue in the contemporary world. Children between the ages of 12 years and 18 years are the most productive age group, but some children may develop behaviors that are undesirable to society by violating laws. The mental health and associated psychosocial factors of such children are lacking in India. It is of utmost importance to understand the mental health aspects of CICL for their rehabilitation, reintegration, and a better society for tomorrow.</p><p><strong>Aim: </strong>This study aimed to compare the psychosocial factors such as psychological adjustment, level of substance abuse, aggression, sensation seeking, self-esteem, and perceived parenting style between CICL and non-CICL.</p><p><strong>Methods: </strong>After obtaining the Institute's Ethics Committee approval (Letter No. IEC/CIP/2020-2021/1207, dated March 22, 2022), 70 CICL were selected from Ranchi district of Jharkhand. To compare, 55 non-CICL were selected with the same gender within the age range of 12-18 years, using a cross-sectional comparative survey research design. A semistructured interview schedule was used to assess the basic demographic and legal history of the children. The Strength and Difficulty Questionnaire, Adolescent Alcohol and Drug Involvement Scale, Buss and Perry Aggression Questionnaire, Arnett Inventory of Sensation Seeking, Rosenberg Self-Esteem Scale, and Parental Style Index were used to compare the psychosocial factors between CICL and non-CICL.</p><p><strong>Results: </strong>The Pearson chi-square test indicated that CICL participants were significantly (<i>P</i> = .001) more likely to be from urban areas, have a history of school dropout and truancy, and come from broken families compared with non-CICL participants. The Mann-Whitney <i>U</i> test & indicated significant differences between CICL and non-CICL in the years of education (<i>P</i> = .001) for both children and their parents. The Mann-Whitney <i>U</i> test found that CICL participants showed significantly higher levels (<i>P</i> = .001) in emotional problems, internalizing attributes, prosocial behavior, level of alcohol/drug involvement, self-esteem, and strictness compared with non-CICL.</p><p><strong>Conclusion: </strong>These findings have significant implications for the field of juvenile justice, highlighting the need for targeted interventions and support systems. Prevention, promotional mental health aspects, and comprehensive rehabilitation plans are crucial for the successful social integration of CICL.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241279546"},"PeriodicalIF":1.9,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Antimanic Effect of Endoxifen in Patients with Bipolar Disorder with Renal Comorbidities: Case Series. 恩多昔芬对合并肾脏疾病的双相情感障碍患者的抗躁作用:病例系列。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-21 DOI: 10.1177/02537176241279547
Astut Kuraria, Rashmi Vishwanath, Anil Kumar M Nagaraj, Savitha Soman, Avinash Kamath
{"title":"The Antimanic Effect of Endoxifen in Patients with Bipolar Disorder with Renal Comorbidities: Case Series.","authors":"Astut Kuraria, Rashmi Vishwanath, Anil Kumar M Nagaraj, Savitha Soman, Avinash Kamath","doi":"10.1177/02537176241279547","DOIUrl":"10.1177/02537176241279547","url":null,"abstract":"<p><p>The conventional and standard pharmacological approaches in the management of bipolar disorders include mood stabilizers and second-generation antipsychotics. However, renal problems owing to the gold standard mood stabilizer, lithium, is three times that of the general population. As bipolar I disorder (BPD I) is associated with overactive protein kinase C (PKC) intracellular signaling, a novel approach in the management of acute mania/mixed affective states of bipolar disorder includes the use of PKC inhibitors, such as Tamoxifen and its derivative metabolite molecule, Endoxifen. Our objective is to report two cases of bipolar disorder that presented in acute manic episodes, with preexisting renal disease, and safe use of Endoxifen as an adjunct/monotherapy for rapid control of symptoms. According to our study, Endoxifen can be used as an anti-manic agent, either as monotherapy or as an adjunct, in patients with renal disease. It can also be used as an effective cover therapy for bipolar disorder patients requiring steroids for the treatment of renal pathology, though long-term studies are needed to assess the long-term safety and efficacy.</p>","PeriodicalId":13476,"journal":{"name":"Indian Journal of Psychological Medicine","volume":" ","pages":"02537176241279547"},"PeriodicalIF":1.9,"publicationDate":"2024-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11572513/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142675673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensory Reactivity Through the Lived Experiences of Parents of Children with Autism Spectrum Disorder: An Exploratory Phenomenological Qualitative Study. 通过自闭症谱系障碍儿童家长的生活经历看感官反应性:探索性现象学定性研究。
IF 1.9
Indian Journal of Psychological Medicine Pub Date : 2024-09-19 DOI: 10.1177/02537176241277545
Selvaganapathy Rajalakshmi, Rajeev Ranjan, Nidhi Joseph Varghese, Ayushi Bharti, Muskan Sinha, Pankaj Kumar, Shamshad Ahmad
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