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Indian Journal of Nephrology最新文献

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Mesangial C1q Deposition in IgA Nephropathy: Does the Classical Complement Pathway Play an Independent Role? IgA肾病系膜C1q沉积：经典补体途径是否起独立作用？
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-10-17 DOI: 10.25259/IJN_424_2024
Gabriele Gaggero, Katia Mazzocco, Barbara Cafferata, Andrea Angeletti
{"title":"Mesangial C1q Deposition in IgA Nephropathy: Does the Classical Complement Pathway Play an Independent Role?","authors":"Gabriele Gaggero, Katia Mazzocco, Barbara Cafferata, Andrea Angeletti","doi":"10.25259/IJN_424_2024","DOIUrl":"10.25259/IJN_424_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"116-117"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763017/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Concomitant Parvovirus B19 and CMV Infection in a Child with Kidney Transplant. 肾移植患儿伴发细小病毒B19和巨细胞病毒感染。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-06-24 DOI: 10.25259/ijn_418_23
Soodeh Shamsadini Moghadam, Hamid Eshaghi, Mastaneh Moghtaderi
{"title":"Concomitant Parvovirus B19 and CMV Infection in a Child with Kidney Transplant.","authors":"Soodeh Shamsadini Moghadam, Hamid Eshaghi, Mastaneh Moghtaderi","doi":"10.25259/ijn_418_23","DOIUrl":"10.25259/ijn_418_23","url":null,"abstract":"<p><p>Parvovirus B19 is a common human infection worldwide and is typically self-limiting in healthy persons but immunocompromised patients require specific treatments. Pretransplant B19 screening doesn't seem to be important or have any impact on the transplantation process but cytomegalovirus (CMV) study is crucial. We present a kidney-transplanted child infected by parvovirus B19 and cytomegalovirus presented with intractable anemia and raised creatinine.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"97-98"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2024 - A Year in Review. 2024年——回顾一年。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2025-01-04 DOI: 10.25259/IJN_821_2024
Vivekanand Jha
{"title":"2024 - A Year in Review.","authors":"Vivekanand Jha","doi":"10.25259/IJN_821_2024","DOIUrl":"10.25259/IJN_821_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"1-2"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pancake Kidney: A Rare Case of Renal Ectopia. 煎饼肾：一例罕见的肾异位。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-09-12 DOI: 10.25259/IJN_401_2024
Abhishek Pratap Singh, Pankaj Beniwal, Vinay Malhotra
{"title":"Pancake Kidney: A Rare Case of Renal Ectopia.","authors":"Abhishek Pratap Singh, Pankaj Beniwal, Vinay Malhotra","doi":"10.25259/IJN_401_2024","DOIUrl":"10.25259/IJN_401_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"111-112"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MicroRNA Expression and Target Prediction in Children with Nephrotic Syndrome. 儿童肾病综合征的MicroRNA表达及靶标预测。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-06-17 DOI: 10.25259/ijn_47_23
Pricilla Charmine, Vettriselvi Venkatesan, Sangeetha Geminiganesan, Bollam Rangaswamy Nammalwar, Mohanapriya Chinambedu Dandapani
{"title":"MicroRNA Expression and Target Prediction in Children with Nephrotic Syndrome.","authors":"Pricilla Charmine, Vettriselvi Venkatesan, Sangeetha Geminiganesan, Bollam Rangaswamy Nammalwar, Mohanapriya Chinambedu Dandapani","doi":"10.25259/ijn_47_23","DOIUrl":"10.25259/ijn_47_23","url":null,"abstract":"<p><strong>Background: </strong>Nephrotic syndrome is a common cause of kidney diseases in children. Many studies have examined the association of microRNAs playing potential roles in many pathophysiological functions. We investigated the expression pattern of the microRNAs miR-17-5P, miR-155p, miR-424-5p in children with steroid sensitive nephrotic syndrome (SSNS) and steroid resistance nephrotic syndrome (SRNS), along with the healthy subjects.</p><p><strong>Materials and methods: </strong>Total RNA was isolated from the urine samples from the three groups (SSNS n = 100, SRNS n = 100, and healthy control group n = 100). Bioinformatics tools such as miRWalk and miR-Tar link were used in predicting targets for the microRNAs. Online database and g profiler software are used to evaluate the targets based on the biological functions. The expression pattern for the candidate microRNAs was carried out using quantitative real time polymerase chain reaction (RT-PCR) equipment.</p><p><strong>Results: </strong>miR-424 and miR-155 were upregulated in SRNS group while miR-17 was downregulated in SRNS group. miR-424-5p and miR-155p was up regulated in SRNS group while miR-17-5p was downregulated.</p><p><strong>Conclusion: </strong>Combined analysis of gene expression along with studied candidate microRNAs can give better understanding of the pathogenesis of childhood nephrotic syndrome.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"59-63"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763170/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Histologic Coexistence of Infection-Related Glomerulonephritis and Thrombotic Microangiopathy. 感染相关性肾小球肾炎和血栓性微血管病罕见的组织学共存。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-08-29 DOI: 10.25259/IJN_304_2024
C V Malathi, Jansi Prema K S, Kishan Aralapuram, Venkataramanan Krishnamoorthy, Anila Abraham Kurien
{"title":"Rare Histologic Coexistence of Infection-Related Glomerulonephritis and Thrombotic Microangiopathy.","authors":"C V Malathi, Jansi Prema K S, Kishan Aralapuram, Venkataramanan Krishnamoorthy, Anila Abraham Kurien","doi":"10.25259/IJN_304_2024","DOIUrl":"10.25259/IJN_304_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"109-110"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Insights into Therapeutic Strategies and Longitudinal Outcomes: A Retrospective Analysis of NELL1 Positive Membranous Nephropathy Cohort. 对治疗策略和纵向结果的见解：NELL1阳性膜性肾病队列回顾性分析。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-10-17 DOI: 10.25259/IJN_443_2024
Gurjot Singh, Harsha Makhija, Pankaj Beniwal, Vinay Malhotra
{"title":"Insights into Therapeutic Strategies and Longitudinal Outcomes: A Retrospective Analysis of NELL1 Positive Membranous Nephropathy Cohort.","authors":"Gurjot Singh, Harsha Makhija, Pankaj Beniwal, Vinay Malhotra","doi":"10.25259/IJN_443_2024","DOIUrl":"10.25259/IJN_443_2024","url":null,"abstract":"<p><p>Membranous nephropathy (MN) is a rare autoimmune disease, in which the circulating autoantibodies against antigens attack podocytes. Neural Epidermal Growth Factor like 1 (NELL1) 1-associated MN is the second most common antigen, following phospholipase A2 receptor. Complementary and alternative medicine and malignancies play a pivotal role in the development of NELL1-MN. This retrospective study describes the clinical characteristics, therapeutic strategies, and longitudinal outcomes in patients with NELL1-MN at our center.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"87-90"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Viral Infection Associated Membranous Nephropathy: Clinical Presentation and Outcomes. 病毒性感染相关膜性肾病：临床表现和结果。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-08-01 DOI: 10.25259/IJN_57_2024
Prabhjot Kaur, Arun Prabhahar, Anitha Vijayakumar Niranjan, Vinod Kumar, Deeksha Pal, Manish Rathi, Harbir Singh Kohli, Aravind Sekar, Ritambhra Nada, Sunil Taneja, Raja Ramachandran
{"title":"Viral Infection Associated Membranous Nephropathy: Clinical Presentation and Outcomes.","authors":"Prabhjot Kaur, Arun Prabhahar, Anitha Vijayakumar Niranjan, Vinod Kumar, Deeksha Pal, Manish Rathi, Harbir Singh Kohli, Aravind Sekar, Ritambhra Nada, Sunil Taneja, Raja Ramachandran","doi":"10.25259/IJN_57_2024","DOIUrl":"10.25259/IJN_57_2024","url":null,"abstract":"<p><strong>Background: </strong>Viral infections can increase the likelihood of an individual developing membranous nephropathy (MN). Limited information is available regarding the treatment approaches for such cases. We conducted a review focusing on hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency virus (HIV)-associated MN.</p><p><strong>Materials and methods: </strong>Our investigation encompassed patient records and cases documented in the literature, utilizing various search engines (PubMed, Scopus, Embase, and Web of Science). We aimed to identify all reported instances of MN associated with HBV, HCV, or HIV infections between 2010 and February 2023 in individuals aged 18 years and above, who underwent PLA2R testing in their serum or kidney biopsy.</p><p><strong>Results: </strong>We analyzed 63 patients with MN associated with viral infections, comprising 7 patients from our center and 57 from the review, consisting of 43% with HIV, 28.5% with HBV, 17.5% with HCV, and 11% with mixed infections. The average age of these patients was 47 years. Their mean proteinuria, serum albumin, and creatinine levels were 7.5 g/day, 2.3 g/dl, and 1.4 mg/dl, respectively. Two-thirds of these cases were PLA2R-related. Notably, 24% of patients achieved remission solely through antiviral treatment, while nearly 40% attained remission with a combination of antiviral and immunosuppression therapies. Eight patients did not achieve remission despite receiving immunosuppressive therapy and antiviral agents.</p><p><strong>Conclusion: </strong>The review suggests that using antiviral medications alone or combined with immunosuppressive therapy can lead to substantial remission in patients with viral-associated MN.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"70-76"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Factor V Leiden Heterozygous Mutation and Hyperhomocysteinemia Presenting with Vascular Rejection and Renal Allograft Infarction. 因子V Leiden杂合突变和高同型半胱氨酸血症表现为血管排斥和同种异体肾移植梗死。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-06-12 DOI: 10.25259/IJN_330_2024
Taruna Pahuja, Sukhwinder Singh Sangha, Akash Sarkar, Raj Kanwar Yadav
{"title":"Factor V Leiden Heterozygous Mutation and Hyperhomocysteinemia Presenting with Vascular Rejection and Renal Allograft Infarction.","authors":"Taruna Pahuja, Sukhwinder Singh Sangha, Akash Sarkar, Raj Kanwar Yadav","doi":"10.25259/IJN_330_2024","DOIUrl":"10.25259/IJN_330_2024","url":null,"abstract":"","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"117-118"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11762829/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sapovirus-Associated Diarrhea in Renal Transplant Patient Treated Without Altering Immunosuppression. 在未改变免疫抑制的情况下治疗肾移植患者的腺病毒相关性腹泻。
IF 0.8
Indian Journal of Nephrology Pub Date : 2025-01-01 Epub Date: 2024-06-29 DOI: 10.25259/ijn_507_23
Ravi Andrews, Mohammed Sajid Abdul Samad, Teja Chimtalapudi, Venkat Ramesh, Muna Ather Ali
{"title":"Sapovirus-Associated Diarrhea in Renal Transplant Patient Treated Without Altering Immunosuppression.","authors":"Ravi Andrews, Mohammed Sajid Abdul Samad, Teja Chimtalapudi, Venkat Ramesh, Muna Ather Ali","doi":"10.25259/ijn_507_23","DOIUrl":"10.25259/ijn_507_23","url":null,"abstract":"<p><p>Solid organ transplant (SOT) recipients are at increased risk of infective diarrheas. In such patients, diarrhea can be complicated by dehydration, leading to acute kidney injury or vascular thrombosis. Viral diarrhea in SOT is reported to be commonly due to cytomegalovirus and norovirus. As sapovirus is not routinely included in diagnostic evaluations, its epidemiology and natural history is not well documented. Anecdotal cases of sapovirus-associated diarrhea in renal transplant recipients have been treated with oral nitazoxanide, often with simultaneous reduction in immunosuppressants. We report sapovirus-associated diarrhea in a renal transplant recipient which responded well within two days to oral nitazoxanide. This, possibly, is the first such report from the Indian subcontinent of adequate control of sapovirus-associated diarrhea without any alteration in the immunosuppressant medications.</p>","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 1","pages":"101-103"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11763154/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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