Indian Journal of Nephrology最新文献_第6页

Unveiling Complexity: Nesidioblastosis in the Nexus of Diabetes and Chronic Kidney Disease. 揭示复杂性：Nesidioblastosis与糖尿病和慢性肾脏疾病的关系。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-06-24 DOI: 10.25259/IJN_90_2024

Niranjana Rekha Paladugu, Muralinath Vukkadala, Anshuman Das, Anuradha Sekaran, Chandhana Merugu

引用次数: 0

An Observational Study on the Clinicopathologic Features of Renal Monoclonal Immunoglobulin Deposition Disease. 肾单克隆免疫球蛋白沉积病临床病理特征的观察研究。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2025-02-20 DOI: 10.25259/IJN_708_2024

C V Malathi, Ks Jansi Prema, Anila Abraham Kurien

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Dissecting the Delicate Dynamics of Donation in Dysglycemia. 剖析血糖异常患者捐献的微妙动态。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2025-01-31 DOI: 10.25259/IJN_623_2024

Nisha Jose, Santosh Varughese

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Evaluating the Impact of Therapeutic Anticoagulation on Acute Kidney Injury in COVID-19: Insights and Future Directions. 评估治疗性抗凝治疗对COVID-19急性肾损伤的影响：见解和未来方向。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-12-26 DOI: 10.25259/IJN_716_2024

Chia Siang Kow, Dinesh Sangarran Ramachandram, Syed Shahzad Hasan, Kaeshaelya Thiruchelvam

引用次数: 0

Efficacy of Regional Citrate versus Heparin Anticoagulation in Continuous Renal Replacement Therapy. 局部柠檬酸盐抗凝与肝素抗凝在持续肾替代治疗中的疗效。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-08-01 DOI: 10.25259/ijn_195_23

Gaurav Bhandari, Debarun Choudhury, Anil Kumar Bhalla, Manish Malik, Anurag Gupta, Vinant Bhargava, Vaibhav Tiwari, Shiv Chadha, Ashwani Gupta, Devinder Singh Rana

{"title":"Efficacy of Regional Citrate versus Heparin Anticoagulation in Continuous Renal Replacement Therapy.","authors":"Gaurav Bhandari, Debarun Choudhury, Anil Kumar Bhalla, Manish Malik, Anurag Gupta, Vinant Bhargava, Vaibhav Tiwari, Shiv Chadha, Ashwani Gupta, Devinder Singh Rana","doi":"10.25259/ijn_195_23","DOIUrl":"https://doi.org/10.25259/ijn_195_23","url":null,"abstract":"Background: Continuous renal replacement therapy (CRRT) is used in hemodynamically unstable patients with acute kidney injury (AKI). Heparin, the most commonly used anticoagulant, has a significant bleeding risk and is associated with heparin-induced thrombocytopenia. Regional citrate anticoagulation is an alternative anticoagulation strategy in CRRT.Materials and methods: A randomized controlled trial was conducted in the Intensive Care Unit over one year, from October 2020 to September 2021, in patients with AKI requiring CRRT. Fifty-two patients were randomized into two groups: group 1 received regional citrate anticoagulation, and group 2 received heparin anticoagulation.Results: The mean age in group 1 was 50.46 years, while it was 49.35 years in group 2. The mean filter lifespan in group 1 was 45.11 hours, while in group 2, it was 26.11 hours and was statistically significant (P < 0.001). The mean effective delivered RRT dose was higher in group 1 (26 ml/kg/hour) compared to group 2 (24.23 ml/kg/hour), which was statistically significant (P < 0.001). Bleeding episodes were higher in group 2 than in group 1 (42.3% vs 11.5%), which was statistically significant (P = 0.027). The RCA group had various electrolyte and metabolic complications, but these were not statistically significant.Conclusion: Regional citrate anticoagulation is better than heparin anticoagulation in terms of filter lifespan, effective delivered RRT dose, bleeding episodes, and metabolic complications.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"380-384"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of POCUS (Point of Care Ultrasound) in Renal Transplantation. POCUS（护理点超声）在肾移植中的应用。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-12-04 DOI: 10.25259/IJN_245_2024

Edwin M Fernando, Suhasini Balasubramaniam

引用次数: 0

Reassessing Metformin's Potential in Autosomal Dominant Polycystic Kidney Disease (ADPKD): A Call for Further Research. 重新评估二甲双胍在常染色体显性多囊肾病（ADPKD）中的潜力：进一步研究的呼吁。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-11-06 DOI: 10.25259/IJN_542_2024

Jasmine Sethi

引用次数: 0

Clinical Application of Genetic Testing in Nephrology. 基因检测在肾病学中的临床应用。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2025-03-11 DOI: 10.25259/IJN_802_2024

Gladwin Jeemon, J K Jayram, Kartik Ganesh, Jithin S Kumar, Sunita Simon, M Abi Abraham

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Diagnosis (by p-RIFLE and KDIGO) and Risk Factors of Acute Kidney Injury in Pediatric Diabetic Ketoacidosis: A Retrospective Study. 儿童糖尿病酮症酸中毒急性肾损伤的诊断（p-RIFLE和KDIGO）和危险因素：回顾性研究。

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-08-01 DOI: 10.25259/IJN_79_2024

Siddarajaiah Likhitha, Ramachandran Rameshkumar, Chinnaiah Govindhareddy Delhikumar, Tamil Selvan

{"title":"Diagnosis (by p-RIFLE and KDIGO) and Risk Factors of Acute Kidney Injury in Pediatric Diabetic Ketoacidosis: A Retrospective Study.","authors":"Siddarajaiah Likhitha, Ramachandran Rameshkumar, Chinnaiah Govindhareddy Delhikumar, Tamil Selvan","doi":"10.25259/IJN_79_2024","DOIUrl":"https://doi.org/10.25259/IJN_79_2024","url":null,"abstract":"Background: There are two criteria to diagnose and stage acute kidney injury (AKI) in children: pediatric-Risk, Injury, Failure, Loss (p-RIFLE) and Kidney Disease Improving Global Outcomes (KDIGO). This study aims to find out the extent of agreement in diagnosis (by p-RIFLE and KDIGO) and risk factors of AKI in pediatric diabetic ketoacidosis (DKA).Materials and methods: A retrospective cohort study involving children aged ≤15 years with DKA was conducted between January 2014 and December 2022. Those with inborn errors of metabolism, septic shock, and urinary tract disease were excluded. The primary outcome was the extent of agreement in diagnosis of AKI by p-RIFLE and KDIGO. The secondary outcomes were staging agreement, risk factors, complications (hypoglycemia, hypokalemia, and cerebral edema), time to resolution of DKA, and hospital and pediatric intensive care units (PICU) stay.Results: Data from 161 patients were collected. Mean (SD) age was 8.6 (3.7) years. Good agreement between p-RIFLE and KDIGO criteria for diagnosis of AKI was noted at admission (Kappa = 0.71, p ≤ 0.001), at 24 hours (Kappa = 0.73, p ≤ 0.001) and discharge (Kappa = 0.60, p ≤ 0.001), and for the staging of AKI at admission (Kappa = 0.81, p ≤ 0.001) at 24 hours (Kappa = 0.75, p ≤ 0.001) and discharge (Kappa = 0.48, p ≤ 0.001). On multivariate analysis, age (≤5 years: aOR = 3.03, 95% CI 1.04-8.79) is an independent risk factor for AKI at discharge by KDIGO. Cerebral edema (n = 6, 3.7%), hypoglycemia (n = 66, 41%), and hypokalemia (n = 59, 36.6%) were noted. Resolution and stay in PICU and hospitals were longer for patients with AKI.Conclusion: p-RIFLE and KDIGO criteria showed good agreement in diagnosis and staging of AKI in pediatric DKA.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"373-379"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Prevalence and Outcomes of BK Polyoma Virus Nephropathy in Living Donor Kidney Transplant Recipients. 活体肾移植受者BK多瘤病毒肾病的患病率和预后

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Indian Journal of Nephrology Pub Date : 2025-05-01 Epub Date: 2024-08-01 DOI: 10.25259/ijn_87_23

Abhyudaysingh Rana, Shyam Bihari Bansal, Camille Nelson Kotton, Amit Kumar Mahapatra, Alka Rana, Sidharth Kumar Sethi, Pranaw Kumar Jha, Ashwini B Gadde, Manish Jain, Dinesh Kumar Yadav, Dinesh Bansal, Vijay Kher

{"title":"The Prevalence and Outcomes of BK Polyoma Virus Nephropathy in Living Donor Kidney Transplant Recipients.","authors":"Abhyudaysingh Rana, Shyam Bihari Bansal, Camille Nelson Kotton, Amit Kumar Mahapatra, Alka Rana, Sidharth Kumar Sethi, Pranaw Kumar Jha, Ashwini B Gadde, Manish Jain, Dinesh Kumar Yadav, Dinesh Bansal, Vijay Kher","doi":"10.25259/ijn_87_23","DOIUrl":"https://doi.org/10.25259/ijn_87_23","url":null,"abstract":"Background: BK polyomavirus nephropathy (BKPyVN) remains an important cause of allograft dysfunction and loss. There is little data about prevalence and outcome of BKPyVN infection from India in living donor kidney transplant recipients.Materials and methods: This is a retrospective analysis of all biopsy-proven BKPyVN among kidney transplant recipients at our center from January 2010 to January 2022. We compared them to age, sex, and type of immunosuppression received matched (1:2) non-BKPyVN-infected recipients transplanted during the same period.Results: During the study period, 2465 patients underwent kidney transplants at our center, of which 26 (1.05%) developed biopsy-proven BKPyVN. Four recipients (16%) lost their graft over a median period of 65 (IQR, 57-83) months from the time of diagnosis. The mean serum creatinine at the recent follow-up was higher in the BKPyVN arm as compared to controls (2.05 ± 1.39 vs 1.35 ± 0.46, p = 0.001.) Both BKPyVN and control arms had similar death-censored graft survival (82% vs 94%, p = 0.09) and patient survival (88% vs 96%, p = 0.184).Conclusion: BKPyVN was uncommon in our kidney transplant recipients. Most patients were able to maintain their kidney function for many years, albeit at a somewhat reduced level compared with the controls, and about a fifth of our patients lost their graft.","PeriodicalId":13359,"journal":{"name":"Indian Journal of Nephrology","volume":"35 3","pages":"343-348"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065578/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0