Immunohematology最新文献_第8页

The effect of probiotic use on ABO antibody titers. 使用益生菌对ABO抗体滴度的影响。

Immunohematology Pub Date : 2022-07-05 DOI: 10.21307/immunohematology-2022-042

Alexandre Geraldo, Larissa Sbors, Flávia Martinello

{"title":"The effect of probiotic use on ABO antibody titers.","authors":"Alexandre Geraldo, Larissa Sbors, Flávia Martinello","doi":"10.21307/immunohematology-2022-042","DOIUrl":"https://doi.org/10.21307/immunohematology-2022-042","url":null,"abstract":"The use of probiotics brings numerous benefits to the immune system, including an increase in antibody production. The development of ABO antibodies may occur naturally due to the bacteria of the intestinal microbiota. However, high titers of ABO antibodies can lead to hemolytic disease of the fetus and newborn and can cause immune transfusion reactions. In this context, this study aimed to evaluate the effect of probiotic consumption on ABO antibody titers in humans. ABO blood group, ABO antibody titer, and fecal pH and Bifidobacteria concentration were determined for 126 healthy individuals before and after daily consumption of yogurt containing Lactobacillus acidophilus and Bifidobacterium lactis over a 1-month period. No changes in fecal pH were observed after probiotic consumption, regardless of ABO blood group. There was, however, an increase in the fecal concentration of Bifidobacteria in individuals with blood group A but not for those with group B or O. A decrease in the titer of anti-B was observed, despite the increase in the concentration of Bifidobacteria in feces being unrelated to fecal pH, in blood group A individuals. Our study, therefore, sought to understand the relationship between probiotics and the antibody titer of the ABO blood system. Despite our findings, further human studies are needed with other probiotic strains and molecular analyses of the intestinal microbiota.","PeriodicalId":13357,"journal":{"name":"Immunohematology","volume":"38 2","pages":"55-61"},"PeriodicalIF":0.0,"publicationDate":"2022-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Using social media to recruit for a face-to-face Specialist in Blood Bank (SBB) Technology program. 利用社交媒体为面对面的血库技术专家 (SBB) 计划招募人才。

Immunohematology Pub Date : 2022-07-05 DOI: 10.21307/immunohematology-2022-043

Karen M Byrne, Ashley A Collins, Robel Seifu, Traci D Paige, Willy A Flegel

引用次数: 0

Unexpected antibody against the high-prevalence P antigen before cardiac surgery. 心脏手术前意外的抗高流行P抗原抗体。

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-033

N García-Tardón, J M M Rondeel, F Danovic, J S Luken, A Winters, P C Ligthart, M De Haas, G Den Besten

{"title":"Unexpected antibody against the high-prevalence P antigen before cardiac surgery.","authors":"N García-Tardón, J M M Rondeel, F Danovic, J S Luken, A Winters, P C Ligthart, M De Haas, G Den Besten","doi":"10.21307/immunohematology-2022-033","DOIUrl":"https://doi.org/10.21307/immunohematology-2022-033","url":null,"abstract":"P is a high-prevalence antigen present in 99.9 percent of the population and is fully developed at birth. P- individuals form naturally occurring antibodies against P, which are often of immunoglobulin (Ig)M and/or IgG type, very potent in complement activation, and able to cause serious intravascular hemolytic transfusion reactions. Some people with anti-P have the rare P1 k phenotype, which lacks P in the presence of P1 and Pk. Blood transfusion in patients with anti-P is challenging, as is described here. A male patient without a history of blood transfusion was admitted for a planned cardiac surgery. The preoperative ABO blood group could not be determined because of unexpected reactions in the reverse grouping, and all red blood cells (RBCs) in the antibody detection test were positive, except for the autocontrol. Further analysis of the patient's sample confirmed the presence of the P1 k phenotype, and anti-P was identified. If transfusion was needed, P- blood would be required, and the only P- RBCs available were at the national Sanquin Bank of Frozen Blood. These units are limited, expensive, and only available for 48 hours after thawing. In the case of massive blood loss, first ABO and Rh-compatible units should be transfused, followed by P- units after the bleeding stops. In our case, the surgery was conducted without transfusion. This case illustrates the importance of preoperative ABO blood group testing and antibody screening in cases where blood loss can be expected. In recent years, more focus has been put on patient blood management. A good collaboration between the local laboratory, surgery department, and dedicated blood transfusion laboratory is critical to prevent unnecessary incompatible blood transfusions with potentially serious outcomes.","PeriodicalId":13357,"journal":{"name":"Immunohematology","volume":"38 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between ABO blood group and COVID-19 infection: an updated systematic review and meta-analysis. ABO血型与COVID-19感染之间的关系:最新的系统综述和荟萃分析

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-034

R G Gheshlagh, M Ansari, P Dalvand, F Shabani, A N Albatineh

{"title":"Association between ABO blood group and COVID-19 infection: an updated systematic review and meta-analysis.","authors":"R G Gheshlagh, M Ansari, P Dalvand, F Shabani, A N Albatineh","doi":"10.21307/immunohematology-2022-034","DOIUrl":"https://doi.org/10.21307/immunohematology-2022-034","url":null,"abstract":"The relationship between ABO blood group and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 - coronavirus disease 19 [COVID-19]) infection has been investigated, and several studies have reported discordant findings. This systematic review and meta-analysis study were conducted to investigate the relationship between ABO blood group and COVID-19 infection. The international databases Institute for Scientific Information (ISI)/Web of Science, PubMed, and Scopus were systematically searched from 1 January 2020 through 14 June 2021. Twenty-seven studies met the inclusion criteria for meta-analysis including 23,285 COVID-19 case subjects and 590,593 control subjects. The odds of having each blood group among COVID-19 patients compared with control subjects were calculated. The random effects model was used to obtain the overall pooled odds ratio (OR). Publication bias and subgroup and sensitivity analyses were performed to explore the source of heterogeneity. According to the random effects model, the results indicated that the pooled estimates of OR (95% confidence interval) for blood groups A, O, B, and AB were 1.26 (1.13-1.40), 0.77 (0.71-0.82), 1.05 (0.99-1.12), and 1.11 (0.99-1.25), respectively. Therefore, individuals infected with COVID-19 have higher odds of having blood group A and lower odds of having blood group O. In conclusion, this study indicated that individuals with blood group A are more susceptible to COVID-19 infection, whereas those with blood group O are less susceptible to COVID-19 infection. However, further studies are warranted to support these findings.","PeriodicalId":13357,"journal":{"name":"Immunohematology","volume":"38 1","pages":"5-12"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

W. John Judd (1945-2021). W.John Judd（1945-2021）。

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-038

引用次数: 0

Life-saving transfusion in autoimmune hemolytic anemia: a case report and procedure review of the dilution method. 自身免疫性溶血性贫血的救命输血:稀释法的病例报告和程序回顾。

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-035

E P Chennamsetty, A Jain, D Kaur, S K Meinia, G Negi, S Agarwal, J Deb

{"title":"Life-saving transfusion in autoimmune hemolytic anemia: a case report and procedure review of the dilution method.","authors":"E P Chennamsetty, A Jain, D Kaur, S K Meinia, G Negi, S Agarwal, J Deb","doi":"10.21307/immunohematology-2022-035","DOIUrl":"https://doi.org/10.21307/immunohematology-2022-035","url":null,"abstract":"A woman with autoimmune hemolytic anemia (AIHA) presented in the emergency department with life-threatening anemia (hemoglobin 3 g/dL). Exaggeration of preexisting chronic anemia to severe anemia after a recent red blood cell (RBC) transfusion led to suspicion of delayed hemolytic transfusion reaction. Given the urgency for transfusion along with a stronger suspicion for coexistence of an alloantibody, the dilution method proposed by Lawrence Petz and George Garratty was used to find an RBC unit for transfusion. An alloantibody with Fyb specificity was identified, which was masked by the coexistent autoantibody. This method is based on the assumption that the titers of an alloantibody are higher than that of autoantibody. Diluting the autoantibody would reveal the alloantibody and, for this purpose, a serial doubling dilution of serum is performed. This method has an important limitation of missing any alloantibodies with titers less than that of the autoantibody. In spite of this, this method may be of use at a resource-poor setting, where trained personnel and other reagents intended for advanced immunohematology methods are unavailable.","PeriodicalId":13357,"journal":{"name":"Immunohematology","volume":"38 1","pages":"13-16"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of thiol reagents to disperse cold autoagglutination. 使用硫醇试剂分散冷自凝。

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-037

T R Wafford

引用次数: 1

Transfusion support for a woman with RHD*09.01.02 and the novel RHD*01W.161 allele in trans. 1例女性RHD*09.01.02和新型RHD*01W的输血支持。161个反式等位基因。

Immunohematology Pub Date : 2022-04-29 DOI: 10.21307/immunohematology-2022-036

K Srivastava, M U Bueno, W A Flegel

{"title":"Transfusion support for a woman with RHD*09.01.02 and the novel RHD*01W.161 allele in trans.","authors":"K Srivastava, M U Bueno, W A Flegel","doi":"10.21307/immunohematology-2022-036","DOIUrl":"10.21307/immunohematology-2022-036","url":null,"abstract":"According to recent work group recommendations, individuals with the serologic weak D phenotypes should be RHD genotyped and individuals with molecular weak D types 1, 2, 3, 4.0, or 4.1 should be treated as D+. We report an African American woman with a long-standing history of metrorrhagia, who presented for infertility evaluation. Blood grouping showed AB with a possible subgroup of A, based on mixed-field agglutination, and a serologic weak D phenotype. Results from routine red cell genotyping for the RHD gene was incongruent with the serologic RhCE phenotype. For the surgical procedure, the patient was hence scheduled to receive group AB, D- RBC transfusions. Subsequent molecular analysis identified the ABO*A2.01 and ABO*B.01 alleles for the ABO genotype and the novel RHD allele [NG_007494.1(RHD):c.611T>A] along with an RHD*09.01.02 allele for the RHD genotype. Using a panel of monoclonal anti-D reagents, we showed the novel RHD(I204K) allele to represent a serologic weak D phenotype, despite occurring as a compound heterozygote, designated RHD*weak D type 161 (RHD*01W.161). Individuals with a weak D type 4.2 allele are prone to anti-D immunization, while the immunization potential of novel RHD alleles is difficult to predict. For now, patients should be treated as D- in transfusion and pregnancy management, when they harbor a novel RHD allele along with any weak D allele other than weak D types 1, 2, 3, 4.0, or 4.1. This study exemplifies strategies for how and when a laboratory should proceed from routine genotyping to nucleotide sequencing before any decisions on transfusion practice is made.","PeriodicalId":13357,"journal":{"name":"Immunohematology","volume":"38 1","pages":"17-24"},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9364384/pdf/nihms-1795193.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40518701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THOSE WERE THE DAYS 那些日子

Immunohematology Pub Date : 2021-09-14 DOI: 10.2307/j.ctv1tgx097.11

引用次数: 16

The Cromer blood group system: an update. 克罗默血型系统:更新。

Immunohematology Pub Date : 2021-09-01 DOI: 10.21307/immunohematology-2021-017

J R Storry, C Lomas-Francis

引用次数: 0