Indian Journal of Psychiatry最新文献

{"title":"Erratum: Clinical practice guidelines for assessment and management of mild neurocognitive disorder.","authors":"","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_148_25","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_148_25","url":null,"abstract":"<p><p>[This corrects the article on p. 21 in vol. 67, PMID: 40046485.].</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 2","pages":"280"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964171/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of school-based intervention on cyberbullying for adolescents.","authors":"Prabhu James Ranjith, Mysore N Vranda, M Thomas Kishore","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_777_23","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_777_23","url":null,"abstract":"<p><strong>Background: </strong>Teenagers are experiencing cyberbullying much more frequently than they did ten years ago and it can affect their mental health and wellbeing. To address these issues, it is necessary to create an efficient school-based model.</p><p><strong>Aim: </strong>The aim was to develop and validate a school-based intervention on cyberbullying for adolescents.</p><p><strong>Methods: </strong>The school-based cyberbullying intervention was developed by reviewing the literature, expert interviews (<i>N</i> = 10), and focus groups with various stakeholders (<i>N</i> = 58). The developed manual was validated by eight experts using face and content validity. The S-CVI was calculated by averaging the I-CVIs for each category of relevance, suitability, and appropriateness.</p><p><strong>Results: </strong>The I-CVI, S-CVI, and kappa values have attained an excellent level of content validity, ranging between 0.85 and 1. The study adopted a universal intervention program. The following were the final components integrated into the content of the school-based cyberbullying intervention manual: (1) Cyberbullying criteria, types, and platforms; (2) reasons for cyberbullying; (3) consequences of cyberbullying; (4) safe use of the internet and social media; (5) coping strategies; (6) family level intervention; and (7) school level intervention.</p><p><strong>Conclusion: </strong>This study outlines the development of a comprehensive school-based cyberbullying intervention for adolescents.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 2","pages":"252-255"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomized sham-controlled trial to study the effect of transcranial direct current stimulation on craving, abstinence, and time to relapse in severe alcohol use disorder.","authors":"Tanmay Joshi, Vishal Dhiman, Rohit Verma, Vijay Krishnan, Aniruddha Basu, Yogesh Singh","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_744_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_744_24","url":null,"abstract":"<p><strong>Background: </strong>Neural circuitry-based treatments, such as transcranial direct current stimulation (tDCS), have demonstrated efficacy in reducing craving in individuals with alcohol use and other addictive substances.</p><p><strong>Aim: </strong>The study aimed to investigate the effectiveness of tDCS on craving, time taken to first drink, and relapse to drinking over 3 months among individuals with severe alcohol use disorder.</p><p><strong>Methods: </strong>A randomized sham-controlled trial included adults aged 18-55 years with severe alcohol dependence. Participants (n = 149) were abstinent from alcohol for at least 3 days, underwent a benzodiazepine washout, and exhibited active craving. tDCS was administered twice daily for 5 consecutive days, with bilateral stimulation being given by placing the anode over F3 and the cathode over F4 to the 'active' (A) and 'sham' (S) intervention groups. Clinical parameters were assessed at baseline, 1 month (1 m), and 3 months (3 m).</p><p><strong>Results: </strong>At completion, out of the 149 randomized subjects (n (A) =75, n (S) =74), 107 participants (n (A) =51, n (S) =56) received the intended tDCS sessions. Baseline characteristics were comparable between the two groups. Intention-to-treat analysis showed significantly lower craving scores in group A than in group S at 1 month and 3 month follow-up time points in comparison to the baseline (baseline: A = 48.33 ± 1.94, S = 48.27 ± 2.45; 1 m: A = 30.37 ± 11.66, S = 33.55 ± 13.73; 3 m: A = 28.50 ± 13.23, S = 34.75 ± 14.07; F (2,294) = 5.52, <i>P</i> < 0.01). Intervention group A also exhibited fewer relapses [3 m A = 33 (44%), 3 m S = 47 (63.5%); χ2 (1) = 5.70, <i>P</i> = 0.01] and a longer time to first drink compared to S (A = 38.50 ± 27.0 days; S = 29.40 ± 23.83 days; t = 2.20, <i>P</i> = 0.03).</p><p><strong>Conclusion: </strong>Adjunctive tDCS demonstrated efficacy in reducing craving and preventing relapse in individuals with severe alcohol dependence. These findings suggest the potential of tDCS as a therapeutic intervention for severe alcohol dependence which is less intense in terms of resources and time and can further be tailored to monitor neurobiological correlates in recovery.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 2","pages":"219-228"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964162/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oxidative and nitrosative stress in bipolar affective disorder and its familial aggregation.","authors":"Harpreet Singh, Abhishek K Singh, Sujita K Kar, Adarsh Tripathi, Pronob K Dalal, Madhu Dikshit","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_396_23","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_396_23","url":null,"abstract":"<p><strong>Introduction: </strong>Bipolar disorder (BD) is one of the most encountered disorders in psychiatric clinics. Despite extensive research and advancements in BD treatment, little is known about the disease's primary etiopathogenesis and relationship with different pathophysiological traits. The present study is aimed to evaluate the pathophysiological role of oxidative and nitrosative stress in BD patients and identify their familial aggregation.</p><p><strong>Methods: </strong>Blood samples from healthy individuals, drug-naive symptomatic BD patients, and their first-degree relatives were obtained, and intracellular reactive oxygen/nitrogen species (ROS/RNS), total nitrites, neuronal nitric oxide synthase (nNOS) mRNA expression, myeloperoxidase (MPO) activity in polymorphonuclear neutrophils (PMNs), and serum cortisol levels were assessed.</p><p><strong>Results: </strong>ROS, MPO activity, total-nitrite content, nNOS expression in PMNs, and serum cortisol concentration were considerably more in BD patients than in healthy volunteers. All these variables showed a substantial correlation with the YMRS score for disease severity and the presence of one or more manic episodes. Additionally, a positive correlation was noted between the MPO activity and serum cortisol levels of BD patients and their first-degree relatives.</p><p><strong>Conclusions: </strong>The results of the present study advance our knowledge about the role of oxidative and nitrosative stress in BD pathophysiology and its familial aggregation. Additionally, the study demonstrates a direct correlation between the disease severity and levels of ROS/RNS, MPO, total nitrite, and nNOS transcripts in PMNs. However, future research with larger and more diverse participant populations is required to understand these pathways for use as potential biomarkers for a deeper understanding of BD pathophysiology and to improve therapeutic strategies.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 2","pages":"209-218"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964165/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disability certification for mental illness in India: 'A bird in the hand is worth two in the bush'.","authors":"Kodigenahalli N Nishanth, Thanapal Sivakumar","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_842_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_842_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 2","pages":"277-278"},"PeriodicalIF":1.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Message from Hon. Treasurer.","authors":"M Aleem Siddiqui","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_17_25","DOIUrl":"https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_17_25","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 Suppl 1","pages":"S4"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932173/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive impairment in alcohol use disorder and clinical practice guidelines for management of long-stay alcohol use disorder patients.","authors":"Samir Kumar Praharaj, Vikas Menon, Shahul Ameen","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_692_24","DOIUrl":"10.4103/indianjpsychiatry.indianjpsychiatry_692_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 1","pages":"144-157"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Message for CPG 2024.","authors":"Savita Malhotra","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_1117_24","DOIUrl":"https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_1117_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 1","pages":"5"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preamble.","authors":"Shiv Gautam, Vihang Vahia, Mohan Dhyani, Debadatta Mohapatra, Parag S Shah","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_1119_24","DOIUrl":"https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_1119_24","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 1","pages":"2-3"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878454/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143566983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Message from the Organizing Committee.","authors":"","doi":"10.4103/indianjpsychiatry.indianjpsychiatry_30_25","DOIUrl":"https://doi.org/10.4103/indianjpsychiatry.indianjpsychiatry_30_25","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"67 Suppl 1","pages":"S5"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11932183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}