Indian Journal of Psychiatry最新文献

{"title":"Semantic confusion between \"MD\" and MDMA in Indian Addiction Psychiatry Practice.","authors":"Ashok Seervi, Indraja Sharma","doi":"10.4103/indianjpsychiatry_1207_25","DOIUrl":"10.4103/indianjpsychiatry_1207_25","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"587-588"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in metabolic parameters in bipolar disorder: A retrospective-to-current evaluation design.","authors":"Gopika Jagota, Aseem Mehra, Swapnajeet Sahoo, Sandeep Grover","doi":"10.4103/indianjpsychiatry_1140_24","DOIUrl":"10.4103/indianjpsychiatry_1140_24","url":null,"abstract":"<p><strong>Background: </strong>There is limited longitudinal data on prevalence of metabolic disturbances in patients with bipolar disorder (BD).</p><p><strong>Aim: </strong>To compare the prevalence of metabolic markers in patients with BD at two different times.</p><p><strong>Materials and methods: </strong>The study participants were assessed at two time points and we used retrospective-to-current evaluation design. The International Diabetes Federation's Consensus Criteria were used to assess the metabolic syndrome (MetS) in seventy-four BD patients at baseline and at least a year following the baseline examination.</p><p><strong>Results: </strong>Participants had an average age of onset of 28.24 years and the mean age at the time of assessment at follow-up was 44.08 years. Most participants were men, from urban locality, married, and unemployed. Approximately one-third of the participants (37.8%) at the baseline assessment and 63.5% at the follow-up evaluation after about 4 years of baseline assessment met the MetS criteria. The most frequent metabolic abnormality was abnormal waist circumference (WC) at both assessments, and when compared to the baseline assessment, a follow-up assessment revealed a significant increase in weight, body mass index, WC, fasting blood glucose, HbA1C, triglycerides, very low-density lipoprotein (VLDL), and prevalence of diabetes mellitus. Diabetes mellitus was shown to have an annual incidence of 2.42%, and the same for hypertension was 5.05%, and and that for dyslipidemia was 4%.</p><p><strong>Conclusion: </strong>Over a 4-year follow-up, there has been a noticeable increase in the prevalence of metabolic parameters and MetS. All this demand careful observation and taking these things into account when selecting drugs.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"538-544"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327405/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychiatric comorbidities and treatment patterns in epilepsy: A retrospective review from a tertiary neuropsychiatric clinic.","authors":"Biswa Ranjan Mishra, Debadatta Mohapatra, Santanu Nath, Archana Mishra, Tathagata Biswas, Bishnu Prasad Sahoo, Rituparna Maiti","doi":"10.4103/indianjpsychiatry_771_25","DOIUrl":"10.4103/indianjpsychiatry_771_25","url":null,"abstract":"<p><strong>Background: </strong>Psychiatric conditions, including neurodevelopmental disorders are common among people with epilepsy (PwEs). However, data comparing their distribution across different epilepsy types are limited, particularly in Indian context.</p><p><strong>Aim: </strong>To explore and compare the psychiatric comorbidities and treatment adherence among focal and generalized epilepsy (FE/GE).</p><p><strong>Methods: </strong>This retrospective chart review included 2,258 PwEs attending a tertiary neuropsychiatry clinic in India between 2013 and 2023. Their sociodemographic and clinical data were compared between FE and GE groups.</p><p><strong>Results: </strong>Nearly 30% had psychiatric comorbidities, most frequently depression (20.6%). Mood and anxiety disorders were more common in FE, while non-affective psychosis was more common in GE. Neurodevelopmental disorders, particularly intellectual disability (ID), were more prevalent in GE (41.9% vs. 16.3%). Medication compliance was suboptimal (60%) and follow-up rates declined over time, reaching 40% at 1-year.</p><p><strong>Conclusion: </strong>PwEs have a high prevalence of psychiatric comorbidities, with differential occurrences across epilepsy types. Inadequate compliance and follow-up rates remain major challenges.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"570-574"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327399/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anemia associated with long-acting injectable aripiprazole in an elderly man.","authors":"Chia-Liang Wu","doi":"10.4103/indianjpsychiatry_392_26","DOIUrl":"10.4103/indianjpsychiatry_392_26","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"589-590"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327395/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and clinical validation of the short version of the NIMHANS-NMHS-2 disability scale.","authors":"T S Jaisoorya, J Lakshmi, V S Binu, Girish N Rao, Vivek Benegal","doi":"10.4103/indianjpsychiatry_352_26","DOIUrl":"10.4103/indianjpsychiatry_352_26","url":null,"abstract":"<p><strong>Background and aim: </strong>This study reports the development of the 8-item NIMHANS-NMHS-2 Disability Scale-Short Version (NNDS-SV) from the 13-item NIMHANS-NMHS-2 Disability Scale (NNDS), aiming to reduce the administration time without compromising its psychometric properties.</p><p><strong>Methods: </strong>An 8-item version was derived from the original 13-item NNDS via expert consensus and high response frequencies. Secondary analysis of the original validation data examined correlations between the NNDS-SV with the NNDS, WHO Disability Assessment Schedule (WHODAS 2.0), and the Brief Psychiatric Rating Scale (BPRS). Independent clinical validation of the NNDS-SV was then undertaken.</p><p><strong>Results: </strong>In secondary analysis, the NNDS-SV correlated strongly with the NNDS (rho = 0.988), WHO-DAS (rho = 0.918), and BPRS (rho = 0.792). Independent clinical validation (n-81) confirmed high concurrent validity with WHODAS (rho = 0.94) and discriminant validity with BPRS (rho = 0.80) with a reduced administration time of 4-6 minutes.</p><p><strong>Conclusion: </strong>The NNDS-SV demonstrates robust psychometric properties and is optimized for large-scale epidemiological studies and has been used in NMHS-2.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"560-563"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-COVID neuropsychiatric symptoms in India: Prevalence, risk factors, and persistence.","authors":"Poulami Laha, Guru S Gowda, Sydney Moirangthem, H B Veenakumari, Bhaskarapillai Binukumar, Venkata Senthil Kumar Reddi, Harish Thippeswamy","doi":"10.4103/indianjpsychiatry_946_25","DOIUrl":"10.4103/indianjpsychiatry_946_25","url":null,"abstract":"<p><strong>Background: </strong>The global research has actively investigated the post-COVID neuropsychiatric symptoms (PCNS). There is a paucity of studies from India that explore long-term PCNS.</p><p><strong>Aim: </strong>This study aims to estimate prevalence, types of PCNS, associated factors (sociodemographic factors, life events, COVID-19-related variables, and vaccination status) and persistence of PCNS after two years.</p><p><strong>Methods: </strong>A cross-sectional study was conducted from October 2022 to October 2023 in a tertiary care hospital. A total of 2,281 randomly selected individuals with reverse transcription polymerase chain reaction-positive for COVID-19 were screened for PCNS. Among 927 participants consented to and completed the telephonic screening for PCNS. Structured clinical interviews for DSM-5-Research Version and World Health Organization-Post-COVID Case Report Form were applied. Descriptive statistics and binary logistic regression analysis were used for data analysis.</p><p><strong>Results: </strong>Median age of individuals was 34 years, and 51.3% being female. Only 21.6% had lifetime PCNS, and 7.3% had persistent PCNS at two years of COVID-19. The common lifetime PCNS were persistent fatigue (15.6%), reduced smell (5.9%), reduced taste (4.8%), anxiety (4.3%), insomnia (3.6%), depressed mood (2.6%), cognitive symptoms (2.6%), and persistent muscle pain (2.6%). The logistic regression analysis revealed a positive association of lifetime PCNS with female gender, preexisting medical comorbidities, symptomatic COVID-19, oxygen supplementation, repeated infections, and life events. Full or partially vaccinated against COVID-19 appeared to be protective against PCNS.</p><p><strong>Conclusion: </strong>About one in five individuals developed lifetime PCNS following COVID. Among them, one in three had persistent PCNS after two years of COVID. Female gender, life events, severity of COVID-19, repeated infection, and Vaccine-naïve status were associated with the development of PCNS.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"552-559"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic barriers to psychiatric care: A comparative cost analysis of essential psychiatric drugs and Janaushadhi alternatives.","authors":"Omar Afroz, Raja Babu Ramawat, Siddharth Sarkar","doi":"10.4103/indianjpsychiatry_851_25","DOIUrl":"10.4103/indianjpsychiatry_851_25","url":null,"abstract":"<p><strong>Background: </strong>Access to affordable medications is an important determinant of treatment adherence and continuity of care. High out-of-pocket expenditure and cost disparities pose barriers and contribute to poor treatment adherence.</p><p><strong>Aim: </strong>We aimed to (1) analyze cost variation among different brands of essential psychiatric medications listed in the National List of Essential Medications (NLEM) 2022, and (2) compare market prices with corresponding generic drugs from the Janaushadhi Scheme.</p><p><strong>Methods: </strong>A cross-sectional price analysis was conducted using the current index of medical specialties (CIMS) and the Janaushadhi database.</p><p><strong>Results: </strong>There was high variation in market costs, ranging from 20.8% (Carbamazepine liquid) to 1604.4% (Clonazepam 0.5 mg). Median branded costs were higher than generic Janaushadhi prices. The cost ratio (branded price/generic price) was highest for Escitalopram 10 mg tablet (>7).</p><p><strong>Conclusion: </strong>Substantial price variation exists even among essential psychiatric medications, potentially undermining equitable access, particularly for economically disadvantaged groups.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"564-569"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327402/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous ejaculation followed by obsessive-compulsive symptoms successfully treated with fluoxetine.","authors":"Mustafa Ozdemir","doi":"10.4103/indianjpsychiatry_440_26","DOIUrl":"10.4103/indianjpsychiatry_440_26","url":null,"abstract":"","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"583-584"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hyderabad declaration on collaboration for global mental health: From illness to wellness.","authors":"Kishan Porandla, Ramaswamy Viswanathan, T S S Rao, Sridevi Mahalingappa, Vishal Madaan, Shabbir Amanullah, Harinder Bains, Sanjay Phadke, M Uma Shankar, V George Reddy, Vishal Akula, Sai Krishna Puli, Srinivas Kambhampati, Ravichandra Gajjala, Uttam Kishan Porandla","doi":"10.4103/indianjpsychiatry_431_26","DOIUrl":"10.4103/indianjpsychiatry_431_26","url":null,"abstract":"<p><p>On the occasion of the Annual National Conference of Indian Psychiatric Society 2025 (ANCIPS 2025), which was held from January 22 to January 25, 2025 with the Theme: \"Neurobiology of Illness to Wellness,\" the organizing committee has prepared the \"Hyderabad Declaration on Collaboration for Global Mental Health: From Illness to Wellness.\" The draft for this declaration has been prepared in consensus with the world leaders of various psychiatric associations belonging to India (IPS), America (APA), Canada (ICPA), and Britain (BIPA). This declaration consists of various key principles. These key principles are made highlighting the shift of the paradigm from illness to wellness, need to empower the health care fraternities, integrating the physical health with mental health, and need for increasing the sensitization and access to mental health and decreasing the stigma on mental health, thus motivating the health fraternities to have a collaborative approach to empower the community with special focus on vulnerable populations including youth and women.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"575-577"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of intermittent theta burst stimulation (iTBS) in schizophrenia with predominant negative symptoms: A brief review.","authors":"Nand Kumar, Gagan Hans, Maria Madiha, Shiv Prasad, Shubham Narnoli","doi":"10.4103/indianjpsychiatry_494_25","DOIUrl":"10.4103/indianjpsychiatry_494_25","url":null,"abstract":"<p><strong>Background: </strong>Negative symptoms of schizophrenia are challenging to treat, contributing to long-term disability and poor prognosis. While conventional TMS has shown proven effective, the evidence supporting intermittent Theta Burst Stimulation (iTBS) is still in the early stages of development.</p><p><strong>Aim: </strong>This review aims to accumulate existing evidence on the safety and effectiveness of iTBS for treating negative symptoms in schizophrenia. A better understanding of its effects and outcomes could lead to more targeted treatments, addressing a gap in current therapeutic strategies.</p><p><strong>Methods: </strong>Search was conducted in three electronic databases: PubMed, ScienceDirect, and Google Scholar, using \"ITBS\", \"Schizophrenia\" and \"Negative symptoms\" as keywords, focusing on RCTs published in the past 10 years related to iTBS and negative symptoms of schizophrenia.</p><p><strong>Results: </strong>Out of 69 identified articles, 9 were included, involving 440 participants between the ages of 18 to 50 years. Total number of sessions ranged from 10-40 sessions. Stimulation sites varied, including bilateral dorsomedial prefrontal cortex (DMPFC), cerebellum (area VII B and midline), and left and right DLPFC. Most studies used stimulation at 100% or 80% motor threshold. All trials applied consistent iTBS parameters at 50 Hz inner train.</p><p><strong>Conclusion: </strong>The present review highlights iTBS as a promising non-invasive treatment for negative symptoms in schizophrenia, offering a novel approach for difficult to treat patients in the short duration of the sessions. Evidence supports its potential as part of an integrated treatment strategy, though further research is needed to confirm long-term safety and effectiveness.</p>","PeriodicalId":13345,"journal":{"name":"Indian Journal of Psychiatry","volume":"68 6","pages":"503-509"},"PeriodicalIF":2.4,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13327407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148375558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}