Indian Journal of Anaesthesia最新文献

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Economic and geographical disparities in global contribution to open access publishing in anaesthesiology: A bibliometric analysis. 全球对麻醉学开放获取出版贡献的经济和地理差异:文献计量学分析。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1281_24
Eric Slawka, Juan Jose Guerra-Londono, Rachel S Hicklen, Sohan Lal Solanki, Daniel Cukierman, Jie Tian, Juan P Cata
{"title":"Economic and geographical disparities in global contribution to open access publishing in anaesthesiology: A bibliometric analysis.","authors":"Eric Slawka, Juan Jose Guerra-Londono, Rachel S Hicklen, Sohan Lal Solanki, Daniel Cukierman, Jie Tian, Juan P Cata","doi":"10.4103/ija.ija_1281_24","DOIUrl":"10.4103/ija.ija_1281_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Open access (OA) publishing improved the reach of scientific discoveries, particularly among researchers in lower-income countries. However, OA publishing still has a global imbalance. This bibliometric analysis evaluates anaesthesia OA journals to explore geographical and economic disparities in publication volume.</p><p><strong>Methods: </strong>We queried the Directory of Open Access Journals for OA anaesthesia-related journals between 2014 and 2024. Data from the included journals were analysed using Scopus, from which we extracted the year of publication and the corresponding author's affiliation. Additional metrics were obtained from each journal website. Countries were then categorised by income level and geographical region.</p><p><strong>Results: </strong>Thirty-four anaesthesiology OA journals were analysed, encompassing 27,634 publications from 120 countries. The leading contributors were India (23.96%), the USA (14.98%) and China (6.54%). Low-income countries accounted for 0.37% of total publications, followed by upper-middle-income (17.97%), lower-middle-income (29.07%), and high-income (52.54%) countries. The geographical distribution of publication volume was as follows: Southeast Asia (25.38%), Europe (23.18%), Western Pacific (18.92%), Americas (23.91%), Eastern Mediterranean (8.03%) and Africa (0.59%). Nineteen journals required a mean article processing charge (APC) of US $2,164.89, accounting for 51.89% of the total publications. India ranked first in non-APC journals, while the USA led in APC journals.</p><p><strong>Conclusion: </strong>While OA publishing enhances accessibility for readers, it still presents challenges for authors, particularly in economically disadvantaged countries. Significant geographical and economic disparities exist in OA publication volume, likely due to limited investment and structural barriers in lower-income countries.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"710-717"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244453/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of perioperative transdermal nicotine patch on postoperative pain: A systematic review and meta-analysis. 围手术期经皮尼古丁贴片对术后疼痛的影响:系统回顾和荟萃分析。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1216_24
Bharat Yalla, Puneet Khanna, Soumya Sarkar, Deepika Lal, Ankita Maheshwari, Manish Gupta, Bhavuk Garg
{"title":"Effect of perioperative transdermal nicotine patch on postoperative pain: A systematic review and meta-analysis.","authors":"Bharat Yalla, Puneet Khanna, Soumya Sarkar, Deepika Lal, Ankita Maheshwari, Manish Gupta, Bhavuk Garg","doi":"10.4103/ija.ija_1216_24","DOIUrl":"10.4103/ija.ija_1216_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Nicotine replacement therapy (NRT) has emerged as a potential intervention for managing perioperative pain. However, their effectiveness remains unclear, as previous studies neither considered the effect of the route of administration nor differentiated the effect between smokers and non-smokers. This systematic review and meta-analysis aimed to determine the effect of a perioperative transdermal nicotine patch on postoperative pain in both smokers and non-smokers compared with a placebo.</p><p><strong>Methods: </strong>We performed a meta-analysis of randomised controlled trials (RCTs) comparing the effects of transdermal nicotine and placebo on postoperative pain. Databases of MEDLINE, EMBASE, CENTRAL, CINAHL, Google Scholar, Web of Science, and the Cochrane Central Register of Controlled Trials were searched. This systematic review and meta-analysis followed the PRISMA guidelines. The findings were evaluated using forest plots and expressed as relative risk (RR) or mean difference (MD) for primary and secondary outcomes.</p><p><strong>Results: </strong>Twelve studies included in the analysis showed no significant difference in pain scores (NRS) at 24 h between the two groups, with an MD -0.24 [95% confidence interval (CI): -0.55, 0.07; P = 0.13] (I<sup>2</sup> = 77%, <i>P</i> < 0.00001), and there was no significant difference in postoperative opioid consumption (morphine equivalent) MD -0.92 (95% CI: -5.04, 3.21; <i>P</i> = 0.66) (I<sup>2</sup> = 23%, <i>P</i> = 0.27). Similarly, the two groups had no significant differences in the time to first rescue analgesia, postoperative nausea and vomiting (PONV), or patient satisfaction. However, the required information size was not achieved for the outcomes of postoperative opioid requirement, reduction in postoperative pain, PONV, and the time for rescue analgesia.</p><p><strong>Conclusion: </strong>The perioperative transdermal nicotine patch did not significantly reduce postoperative pain scores compared with placebo. There appears to be a significant reduction in smokers, but the evidence is inadequate to conclude this finding.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"664-674"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of head rotation on oropharyngeal leak pressure of LMA-ProtectorTM and i-gel® in paralysed, anaesthetised patients: A randomised comparative study. 头部旋转对瘫痪、麻醉患者LMA-ProtectorTM和i-gel®口咽漏压的影响:一项随机对照研究
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1164_24
Gauri Sharma, Jaspal Singh Dali, Megha Soni, Rashmi Virmani
{"title":"Influence of head rotation on oropharyngeal leak pressure of LMA-Protector<sup>TM</sup> and i-gel® in paralysed, anaesthetised patients: A randomised comparative study.","authors":"Gauri Sharma, Jaspal Singh Dali, Megha Soni, Rashmi Virmani","doi":"10.4103/ija.ija_1164_24","DOIUrl":"10.4103/ija.ija_1164_24","url":null,"abstract":"<p><strong>Background and aims: </strong>The most important parameter to provide adequate and safe ventilation for the supralaryngeal airway device (SAD) is its sealing effectivity measured as oropharyngeal leak pressure (OPLP). Various studies have been conducted to elucidate the effects of head extension and flexion on the OPLP of SAD devices; however, the literature regarding the influence of head rotation on OPLP is limited. The primary objective of the study was to evaluate and compare the influence of head rotation on the OPLP of LMA-Protector<sup>TM</sup> with i-gel® in paralysed, anaesthetised patients.</p><p><strong>Methods: </strong>Sixty patients of either gender scheduled for elective laparoscopic cholecystectomy were randomly allocated into two Group, namely group L and Group I. Ten min following the induction of pneumoperitoneum, OPLP was recorded at 0°, 30°, and 60° left head rotation. The insertion characteristics of both SADs were also recorded and compared. Normally distributed continuous variables were compared using the unpaired <i>t</i>-test. Categorical variables were analysed using either the Chi-square test or Fisher's exact test. A paired <i>t</i>-test was used for the group analysis.</p><p><strong>Results: </strong>OPLP of Group L and Group I was comparable in neutral and 30° head rotation. OPLP was significantly higher in the LMA-Protector compared to the i-gel® at 60° head rotation (<i>P</i> = 0.041). In both the study groups, there was a significant decrease in OPLP when the head was turned from neutral to 60°.</p><p><strong>Conclusion: </strong>OPLP of Group L and Group I was comparable in neutral and 30° head rotation. LMA-Protector<sup>TM</sup> offered better OPLP as compared to i-gel® at 60° head rotation.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"681-686"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244456/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infrared thermography for chronic pain assessment and efficacy of treatment. 红外热成像对慢性疼痛的评价及治疗效果。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_387_25
Sonia Bansal, Kamath Sriganesh, Kondavagilu Ramaprasannakumar Shwethashri
{"title":"Infrared thermography for chronic pain assessment and efficacy of treatment.","authors":"Sonia Bansal, Kamath Sriganesh, Kondavagilu Ramaprasannakumar Shwethashri","doi":"10.4103/ija.ija_387_25","DOIUrl":"10.4103/ija.ija_387_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"742-743"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the correlation between pre-anaesthetic P-POSSUM score, ultrasound muscle assessment and frailty index on perioperative outcome - An observational trial. 麻醉前P-POSSUM评分、超声肌肉评估和衰弱指数与围手术期预后的相关性评价——一项观察性试验。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1338_24
Sanchi Sunil Bhalerao, Vanita Ahuja, Deepak Thapa, Sukanya Mitra, Ashok K Attri, Sudesh K Arya, Sidharth Garg
{"title":"Evaluation of the correlation between pre-anaesthetic P-POSSUM score, ultrasound muscle assessment and frailty index on perioperative outcome - An observational trial.","authors":"Sanchi Sunil Bhalerao, Vanita Ahuja, Deepak Thapa, Sukanya Mitra, Ashok K Attri, Sudesh K Arya, Sidharth Garg","doi":"10.4103/ija.ija_1338_24","DOIUrl":"10.4103/ija.ija_1338_24","url":null,"abstract":"<p><strong>Background and aims: </strong>Bedside muscle ultrasonography has emerged as a clinical tool for sarcopenia and perioperative outcomes. We aimed to find a correlation between the pre-anaesthetic Portsmouth Physiological and Operative Severity score for the enumeration of mortality and morbidity (P-POSSUM), Fried Frailty Phenotype (FrFP) and ultrasound-guided (USG) muscle cross-sectional area (CSA) with morbidity and mortality outcomes in elective surgeries.</p><p><strong>Methods: </strong>This prospective observational trial included 150 patients aged 18-80 years undergoing low-risk (<i>n</i> = 50), intermediate-risk (<i>n</i> = 50), and high-risk (<i>n</i> = 50) surgeries. Preoperative P-POSSUM scores, USG CSA of psoas major and rectus femoris muscles and FrFP were recorded. Postoperative outcomes on days 1, 2 and 3 and then until patient discharge were observed. A <i>P</i> value < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>Demographics of patients were similar in age, gender, weight, body mass index and pre-frail status. A strong correlation coefficient was observed for physiological score, operative severity score, CSA of psoas major and CSA of rectus femoris. A weak strength correlation coefficient was observed between FrFP and CSA of psoas major, regarding 30-day morbidity and mortality. The area under the curve (AUC) - 0.74 for psoas major had moderate predictive ability, and AUC-0.84 for rectus femoris showed a strong predictive ability against 30-day mortality in high-risk surgeries. The Hosmer-Lemeshow goodness-of-fit test analysis revealed a mortality ratio of 0.98.</p><p><strong>Conclusion: </strong>P-POSSUM and CSA of psoas major and rectus femoris had a statistically significant positive correlation to predict perioperative 30-day mortality in survivor versus non-survivor patients of high-risk surgeries.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"700-709"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between microcuff and wire-reinforced endotracheal tubes on postoperative complications in anterior cervical discectomy and fusion: A randomised study. 颈前椎间盘切除术融合术后并发症的比较:一项随机研究。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1046_24
S R Janani, Dheeraj Masapu, D N Dhananjay, Satish Rudrappa, Ramachandran Govindasamy, T Jagadish
{"title":"Comparison between microcuff and wire-reinforced endotracheal tubes on postoperative complications in anterior cervical discectomy and fusion: A randomised study.","authors":"S R Janani, Dheeraj Masapu, D N Dhananjay, Satish Rudrappa, Ramachandran Govindasamy, T Jagadish","doi":"10.4103/ija.ija_1046_24","DOIUrl":"10.4103/ija.ija_1046_24","url":null,"abstract":"<p><strong>Background and aims: </strong>This randomised study investigated whether microcuff endotracheal tubes (ETT) reduce postoperative complications compared to wire-reinforced ETT in patients undergoing anterior cervical discectomy and fusion (ACDF).</p><p><strong>Methods: </strong>In total, 120 patients were randomly assigned to receive either a microcuff ETT (Group M) or a wire-reinforced ETT (Group W) during surgery. Intraoperative cuff pressure changes due to retractor use were noted. Postoperative complications such as vocal cord palsy and airway oedema were observed at extubation, and hoarseness, sore throat, dysphagia, and stridor were assessed at 6, 24, and 48 hours after extubation. Data were analysed using SPSS v. 24 software. The sample size was calculated from a study based on the primary outcome, which is hoarseness of voice, to detect a 16% difference between the two groups, with 80% power and a significance level of <i>P</i> < 0.05.</p><p><strong>Results: </strong>Both groups had similar baseline characteristics. The initial and post-retraction cuff inflation volumes were significantly lower in Group M. Cuff pressure increased significantly after retractor use in both groups (<i>P</i> < 0.001), with a greater increase observed in Group W. While no patient experienced stridor, vocal cord palsy, or airway oedema, the incidence of postoperative hoarseness was significantly lower in Group M (16.6% vs 6.7%) (<i>P</i> = 0.040). There were no significant differences in the rates of sore throat or dysphagia.</p><p><strong>Conclusion: </strong>Microcuff ETT may offer advantages over wire-reinforced ETT during ACDF by potentially reducing the incidence of hoarseness, likely due to lower cuff pressure with preserved tracheal mucosal perfusion, and requiring less readjustment of the cuff after retractor application.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"675-680"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extracorporeal membrane oxygenation (ECMO) rescue for unanticipated failed airway management - Fact or Fiction? 体外膜氧合(ECMO)抢救意外气道管理失败-事实还是虚构?
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_462_25
Ayten Saracoglu, Rakesh Garg, Bushra Abdallah, Ibrahim Fawzy, Anil Patel, Kemal T Saracoglu
{"title":"Extracorporeal membrane oxygenation (ECMO) rescue for unanticipated failed airway management - Fact or Fiction?","authors":"Ayten Saracoglu, Rakesh Garg, Bushra Abdallah, Ibrahim Fawzy, Anil Patel, Kemal T Saracoglu","doi":"10.4103/ija.ija_462_25","DOIUrl":"10.4103/ija.ija_462_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"633-634"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative efficacy of different doses of dexmedetomidine in sedation during awake fibreoptic nasotracheal intubation: A systematic review and meta-analysis. 不同剂量右美托咪定在清醒纤维鼻气管插管镇静中的比较疗效:一项系统回顾和荟萃分析。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_120_25
Mohd Ovais Alam, Nishaant Ramasamy, Gowtham Kannan, Mogan Kaviprawin, Bijaya Kumar Padhi, Aravind P Gandhi
{"title":"Comparative efficacy of different doses of dexmedetomidine in sedation during awake fibreoptic nasotracheal intubation: A systematic review and meta-analysis.","authors":"Mohd Ovais Alam, Nishaant Ramasamy, Gowtham Kannan, Mogan Kaviprawin, Bijaya Kumar Padhi, Aravind P Gandhi","doi":"10.4103/ija.ija_120_25","DOIUrl":"10.4103/ija.ija_120_25","url":null,"abstract":"<p><strong>Background and aims: </strong>Awake fibreoptic nasotracheal intubation (AFONI) is critical in patients with difficult airways, requiring effective sedation that preserves spontaneous ventilation and airway reflexes. This systematic review evaluated the comparative efficacy of various dexmedetomidine doses in sedation for AFONI, with a meta-analysis focusing on 0.5, 1, and 1.5 µg/kg doses.</p><p><strong>Methods: </strong>Databases searched included PubMed, EMBASE, Web of Science, and Cochrane, initially up to 5 May 2024, with a top-up search on 15 April 2025. Five studies were systematically reviewed, covering dexmedetomidine doses of 0.5, 0.7, 1, 1.5, and 2 µg/kg. A meta-analysis was conducted on two studies with doses of 1 and 1.5 µg/kg, and two studies with doses of 0.5 and 1.5 µg/kg. Primary outcomes included patient comfort, intubation scores, and sedation levels; secondary outcomes included vocal cord function, cough, and limb movements. Continuous and dichotomous outcome variables were summarised as mean difference and risk ratio, with a 95% confidence interval, using RStudio 2024.12.0 (PROSPERO ID: CRD42024541481).</p><p><strong>Results: </strong>Meta-analysis showed that 1.5 µg/kg did not significantly improve patient comfort or intubation conditions compared to 1 and 0.5 µg/kg. No significant differences were observed in intubation comfort scores, sedation levels, or patient satisfaction across the various doses.</p><p><strong>Conclusions: </strong>Dexmedetomidine at 0.5 and 1 µg/kg offers effective sedation and patient comfort comparable to 1.5 µg/kg during AFONI. Given the very low to moderate certainty of evidence, further large-scale studies are warranted to establish optimal dosing for enhanced patient experience and reduced side effects across various clinical settings.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"650-663"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244460/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ropivacaine and dexamethasone: Better to separate than mixing together. 罗哌卡因和地塞米松:分开使用比混合使用好。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-07-01 Epub Date: 2025-06-12 DOI: 10.4103/ija.ija_1269_24
Chitta Ranjan Mohanty, Amiya Kumar Barik, Rakesh Vadakkethil Radhakrishnan, Divya Mocharla
{"title":"Ropivacaine and dexamethasone: Better to separate than mixing together.","authors":"Chitta Ranjan Mohanty, Amiya Kumar Barik, Rakesh Vadakkethil Radhakrishnan, Divya Mocharla","doi":"10.4103/ija.ija_1269_24","DOIUrl":"10.4103/ija.ija_1269_24","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 7","pages":"733"},"PeriodicalIF":2.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of phenylephrine, ephedrine, and norepinephrine for the prevention and treatment of spinal-induced hypotension in pre-eclamptic patients undergoing caesarean section: A systematic review and network meta-analysis. 苯肾上腺素、麻黄碱和去甲肾上腺素预防和治疗剖宫产子痫前期患者脊柱性低血压的比较:系统综述和网络荟萃分析。
IF 2.9
Indian Journal of Anaesthesia Pub Date : 2025-06-01 Epub Date: 2025-05-14 DOI: 10.4103/ija.ija_62_25
Ahmed S Badran, Karim S Shata, Ahmed Elgammal, Ahmed A Samir, Mostafa O Farag, Salma Allam, Ahmed Samy
{"title":"Comparison of phenylephrine, ephedrine, and norepinephrine for the prevention and treatment of spinal-induced hypotension in pre-eclamptic patients undergoing caesarean section: A systematic review and network meta-analysis.","authors":"Ahmed S Badran, Karim S Shata, Ahmed Elgammal, Ahmed A Samir, Mostafa O Farag, Salma Allam, Ahmed Samy","doi":"10.4103/ija.ija_62_25","DOIUrl":"10.4103/ija.ija_62_25","url":null,"abstract":"<p><strong>Background and aims: </strong>Spinal-induced hypotension in parturients with pre-eclampsia (PE) can lead to adverse perinatal outcomes, making effective prophylaxis and treatment crucial. We aim to compare the prophylactic and therapeutic roles of phenylephrine, ephedrine, and norepinephrine (NE) in treating post-spinal hypotension in PE patients.</p><p><strong>Methods: </strong>We conducted a comprehensive search of various databases up to June 2024, focusing on randomised clinical trials (RCTs). Standardised mean differences (SMDs) were used for continuous outcomes, while odds ratios (ORs) were employed for binary outcomes. Analyses were performed using R with both fixed-effect and random-effects models.</p><p><strong>Results: </strong>Nine RCTs (804 patients) were included in the analysis. Therapeutic comparisons revealed no differences in mean arterial pressure between NE and ephedrine (SMD = 0.51, 95% CI: -0.49, 1.53) or phenylephrine and ephedrine (SMD = 0.90, 95% CI: -0.01, 1.82). Phenylephrine was associated with a significantly higher risk of bradycardia compared to ephedrine (OR = 14.34, 95% CI: 1.8, 113.64, <i>P</i> = 0.018), whereas NE showed an insignificant difference (OR = 2.54, 95% CI: 0.27, 23.94). NE significantly improved the umbilical artery pH compared to ephedrine (SMD = 0.32, 95% CI: 0.02, 0.62, <i>P</i> = 0.036). No significant differences were identified in nausea or vomiting. Prophylactic comparisons revealed no significant differences between phenylephrine and NE for hypotension (OR = 0.98, 95% CI: 0.22, 4.26). For bradycardia, no difference was observed between NE and ephedrine (OR = 0.08, 95% CI: 0.002, 3.33) or phenylephrine and ephedrine (OR = 0.19, 95% CI: 0.006, 74).</p><p><strong>Conclusions: </strong>Phenylephrine, ephedrine, and NE exhibit comparable haemodynamic effects and maternal side effects, although phenylephrine increases the risk of bradycardia. NE improves umbilical artery pH.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 6","pages":"526-539"},"PeriodicalIF":2.9,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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