Indian Journal of Anaesthesia最新文献

{"title":"Revisiting the deep rectus sheath block: An anatomical mismatch for optimal analgesia.","authors":"Kartik Sonawane, Namburi R Naveena, Tuhin Mistry","doi":"10.4103/ija.ija_534_25","DOIUrl":"10.4103/ija.ija_534_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1078-1081"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imputation of arterial oxygen partial pressures using pulse oximetry in surgical patients under general anaesthesia: A prospective cohort study.","authors":"Mohamad F El-Khatib, Marwan Rizk, Amro Khalili, Thuraya HajAli, Ibrahim El Mallah, Rasha Shreim, Carine Zeeni","doi":"10.4103/ija.ija_153_25","DOIUrl":"10.4103/ija.ija_153_25","url":null,"abstract":"<p><strong>Background and aims: </strong>Monitoring oxygen saturation (SpO₂) during general anaesthesia using pulse oximetry is mandatory, though it may not always reflect the actual oxygenation status. Arterial blood gas (ABG) analysis remains the gold standard for measuring the partial pressure of oxygen (PaO₂), but it is invasive and limited by complications. This study aims to validate five existing equations for predicting PaO₂ from SpO₂ and, if applicable, to derive and validate a new equation in adult patients undergoing surgeries under general anaesthesia.</p><p><strong>Methods: </strong>A prospective cohort study was conducted on adult patients undergoing general anaesthesia and requiring ABG measurements at several time points intraoperatively. Using SPSS software, a Bland-Altman analysis was performed to assess the agreement between derived and measured PaO2 values using five existing equations. Regression analysis was then performed to develop a new equation for predicting PaO₂, which was validated in a second cohort.</p><p><strong>Results: </strong>During the initial phase, 150 ABG samples were collected from 83 patients. Bland-Altman analysis revealed weak agreements with all existing equations. A new logarithmic equation, El-Khatib's equation (PaO₂ = 10^-25.6 × SpO₂ ^13.9), was derived. The validation phase involved 150 ABG samples from 65 patients, demonstrating strong agreement with El-Khatib's equation (systematic bias of 13 mmHg, limits of agreement: -189 to 214 mmHg).</p><p><strong>Conclusion: </strong>Five existing equations for predicting PaO₂ from SpO₂ revealed weak agreement in adult patients under general anaesthesia. El-Khatib's equation demonstrated strong potential for predicting PaO₂, providing a reliable non-invasive alternative for determining PaO₂ in clinical practice.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1047-1054"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dexmedetomidine target-controlled infusion-based sedoanalgesic technique for awake craniotomy in brain neoplasms: A case series.","authors":"Shagun B Shah, Rajiv Chawla, Charanjeet Kaur, Nikhil Bhasin","doi":"10.4103/ija.ija_630_25","DOIUrl":"10.4103/ija.ija_630_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1089-1091"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple and effective \"adhesive-flag\" fixation method for perineural catheters.","authors":"Amjad Maniar, Rammurthy Kulkarni, Archana Areti","doi":"10.4103/ija.ija_833_25","DOIUrl":"10.4103/ija.ija_833_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1091-1093"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment to \"Association between preoperative frailty and postoperative delirium and cognitive dysfunction in elderly patients undergoing surgery under general anaesthesia\".","authors":"Abhishek Kumar, Tanvi Bhargava","doi":"10.4103/ija.ija_781_25","DOIUrl":"10.4103/ija.ija_781_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1086"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stopping versus continuing renin-angiotensin system inhibitors before surgery: An updated systematic review and meta-analysis of randomised controlled trials.","authors":"Marwah Algodi, Omar Saab, Alhareth Al-Sagban, Hashim T Hashim, Ahmed D Al-Obaidi, Mohanad Albayyaa, Bashar Al-Hemyari","doi":"10.4103/ija.ija_416_25","DOIUrl":"10.4103/ija.ija_416_25","url":null,"abstract":"<p><strong>Background and aims: </strong>The optimal perioperative management of patients chronically using renin-angiotensin system inhibitors (RASIs) is still uncertain. This study aims to compare the outcomes of withholding versus continuing RASIs before surgery, focusing on efficacy and safety.</p><p><strong>Methods: </strong>A systematic review and meta-analysis synthesising evidence from randomised controlled trials (RCTs) obtained from PubMed, CENTRAL, Scopus, and Web of Science until September 2024. Using Stata MP v. 17, we used the fixed-effects model to report dichotomous outcomes by using the risk ratio (RR) with a 95% confidence interval (CI).</p><p><strong>Results: </strong>Ten RCTs with 3,740 patients were included. There was no statistical difference between both groups regarding the incidence of major adverse cardiac events (MACE) [Risk ratio (RR): 0.99; 95% confidence interval (CI): 0.84, 1.16; P = 0.88], all-cause mortality (RR: 0.88; 95% CI: 0.44, 1.78; <i>P</i> = 0.72), myocardial infarction (MI) (RR: 1.67; 95% CI: 0.61, 4.58; <i>P</i> = 0.32), heart failure/acute pulmonary oedema (RR: 1.87; 95% CI: 0.51, 6.84; <i>P</i> = 0.34), stroke (RR: 1.22; 95% CI: 0.35, 4.24; <i>P</i> = 0.75), postoperative hypotension (RR: 0.85; 95% CI: 0.66, 1.10; <i>P</i> = 0.22), perioperative hypertension (RR: 1.21; 95% CI: 1.00, 1.46; <i>P</i> = 0.05), and acute kidney injury (AKI) (RR: 1.01; 95% CI: 0.80, 1.26; <i>P</i> = 0.97). However, withholding RASIs was significantly associated with a decreased incidence of intraoperative hypotension (RR: 0.82; 95% CI: 0.75, 0.89; <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Stopping RASIs in patients undergoing surgery was not associated with a higher risk of postoperative complications, such as MACE, all-cause mortality, myocardial infarction, heart failure/acute pulmonary oedema, stroke, or AKI. Conversely, discontinuing RASIs notably reduced the incidence of intraoperative hypotension.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"984-998"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of ageing on sevoflurane's hypnotic potency and induction kinetics during wash-in period: A prospective observational study.","authors":"Qian-Yun Pang, Ya-Jun Yang, Yu-Mei Feng, Hong-Liang Liu","doi":"10.4103/ija.ija_424_25","DOIUrl":"10.4103/ija.ija_424_25","url":null,"abstract":"<p><strong>Background and aims: </strong>The age-dependent decline in sevoflurane's minimum alveolar concentration is well established. However, the relationship between ageing and its hypnotic potency at the effect-site concentration (Ceff) remains unclear. This study aimed to evaluate the impact of ageing on sevoflurane's hypnotic potency and induction kinetics during the wash-in period.</p><p><strong>Methods: </strong>This prospective observational study enroled 83 female patients stratified by age into four decades: 30-39, 40-49, 50-59, and 60-69 years. Anaesthesia was induced using 5% sevoflurane in a non-rebreathing manner. We continuously recorded bispectral index (BIS) values and end-tidal sevoflurane concentrations during the 4 min wash-in period, with Ceff values calculated through pharmacokinetic modelling. Subsequently, the end-tidal concentration was maintained at 1.5% for 20 min (10 min equilibration + 10 min stabilisation) at 2 L/min to achieve a cerebral steady-state, and the final stabilised BIS value was calculated. One-way ANOVA with Bonferroni post-hoc correction or Kruskal-Wallis test was used to compare continuous variables. Pearson's Chi-square test was used to compare categorical variables, with the significant difference set at <i>P</i> < 0.05.</p><p><strong>Results: </strong>During the wash-in period, the 60-69-year group exhibited a prolonged time from awakening to BIS 50 compared to younger cohorts (<i>P</i> < 0.05 or < 0.01). Ceff values exhibited progressively delayed kinetics with increasing age, but Ceff values of sevoflurane at BIS 50 were not different across the four age groups (<i>P</i> > 0.05). At a steady state of 1.5% sevoflurane anaesthesia, the intergroup analysis revealed no significant variations in BIS values.</p><p><strong>Conclusion: </strong>The hypnotic potency of sevoflurane is preserved among female patients aged 30-69 years despite delayed induction kinetics in older individuals.</p>","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1061-1068"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445756/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the deep rectus sheath block: An anatomical mismatch for visceral analgesia.","authors":"Francesco Marrone, Marco Tomei, Carmine Pullano, Pierfrancesco Fusco","doi":"10.4103/ija.ija_929_25","DOIUrl":"10.4103/ija.ija_929_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1081-1082"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145112974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding number needed to treat (NNT): A practical guide for anaesthesia and critical care clinicians.","authors":"Venkata Ganesh, Neeru Sahni, Rakesh Garg","doi":"10.4103/ija.ija_1000_25","DOIUrl":"10.4103/ija.ija_1000_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"969-974"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to comments on \"Association of frailty with postoperative outcomes in patients undergoing elective non-malignant abdominal surgeries under general or neuraxial anaesthesia\".","authors":"Rinu Raju, Pooja Singh, Pranita Mandal, Vaishali Waindeskar, Sunaina T Karna","doi":"10.4103/ija.ija_911_25","DOIUrl":"10.4103/ija.ija_911_25","url":null,"abstract":"","PeriodicalId":13339,"journal":{"name":"Indian Journal of Anaesthesia","volume":"69 10","pages":"1084-1085"},"PeriodicalIF":1.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145113022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}