{"title":"Psychodermatology in India: Bridging the Mind-Skin Divide and the Path Forward.","authors":"Tarun Narang, Aysha Najeeb","doi":"10.4103/idoj.idoj_455_26","DOIUrl":"https://doi.org/10.4103/idoj.idoj_455_26","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"17 3","pages":"321-323"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychodermatology: Current Scope and Future Prospects.","authors":"Mehul Tyagi, Pankhuri Dudani, Ishan Pandya","doi":"10.4103/idoj.idoj_543_25","DOIUrl":"https://doi.org/10.4103/idoj.idoj_543_25","url":null,"abstract":"<p><strong>Abstract: </strong>The mind and the body represent a continuum: intricately connected, influencing each other, and being inevitably influenced by anything affecting either one of them. The field of psychodermatology explores this complex bidirectional relationship, offering insights into the mechanisms and extent of psychological influence on the behavior of dermatological conditions, and vice versa. The skin has a close relationship with the mind, potentially due to the common ectodermal origin of the brain and skin, and by the visible and hence psychosocially impactful nature of chronic skin diseases, a factor less relevant for other organ systems. Despite growing evidence supporting this connection, both causally and therapeutically, the field remains peripheral in mainstream dermatology practice. Thirty to forty percent of dermatology patients suffer from psychological issues, yet only up to 15 percent receive appropriate psychological support. This article examines the status, expanding scope, and future prospects of psychodermatology with particular emphasis on the role of artificial intelligence.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":"17 3","pages":"324-330"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ocular Complications of Cosmetic Laser Use in Patients and Treating Doctors/Estheticians: A Systematic Review of Case Reports and Case Series.","authors":"Kaberi Biswas, Feroze Kaliyadan","doi":"10.4103/idoj.idoj_26_25","DOIUrl":"10.4103/idoj.idoj_26_25","url":null,"abstract":"<p><strong>Abstract: </strong>Cosmetic laser treatments are extremely popular and widely available. Along with increasing laser use, there are also reports of rising adverse effects, the majority of which are noted to involve the eye. This systematic review was conducted to assess the nature and severity of ocular injuries associated with various cosmetic lasers in both patients and laser operators and to deduce methods of reducing such incidents. A total of 24 case reports/case series involving ocular adverse effects of cosmetic lasers were retrieved using the following keywords: \"cosmetic laser,\" \"patient,\" \"aesthetician,\" \"laser operator,\" \"dermatologist,\" and \"ocular injury,\" either singly or combined. The databases searched include PubMed, Cochrane Library, Embase, and Science Direct. Anterior uveitis was noted to be the commonest adverse effect, and retinal laser burns were the most vision-threatening. Ocular morbidities in the treating physician/esthetician were also noted, many of which were accidental in nature.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"340-346"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147485637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cristiane R Gruber, Thelma L Skare, Marcos F Sigwalt, Graziela J Crescente Rastelli, Fernando I Tabushi, Allan F Giovanini
{"title":"Characterization of Immunolocalization of IP3R-1 in Skin Epithelium and its Changes in Non-Melanoma Skin Cancer: An Immuno-Histochemical and Clinical-Pathological Study.","authors":"Cristiane R Gruber, Thelma L Skare, Marcos F Sigwalt, Graziela J Crescente Rastelli, Fernando I Tabushi, Allan F Giovanini","doi":"10.4103/idoj.idoj_694_25","DOIUrl":"10.4103/idoj.idoj_694_25","url":null,"abstract":"<p><strong>Background: </strong>The calcium ion (Ca 2+ ) signaling is a fundamental cellular process vital for proliferation and differentiation. Its dysregulation is a recognized driver of carcinogenesis, contributing to uncontrolled cellular growth, survival, and metastasis. The inositol 1,4,5-triphosphate receptor (IP3R), a pivotal Ca 2+ channel located primarily on the endoplasmic reticulum, is critical for mediating intracellular Ca 2+ release and is implicated in cancer development.</p><p><strong>Aim and objectives: </strong>To evaluate the immunolocalization of IP3R-1 in normal skin, squamous cell dysplasia, squamous cell carcinoma (SCC), and basal cell carcinoma (BCC), and to determine its association with clinicopathological features such as genesis, infiltration, differentiation, and aggressiveness.</p><p><strong>Patients and methods: </strong>This investigation employed a descriptive and analytical study design to examine IP3R-1 expression within human tissue samples. The methodology involved collecting and analyzing archival specimens from patients diagnosed with non-melanoma skin cancers and pre-malignant lesions, as well as normal skin samples for comparative assessment. The role of IP3R-1 in skin cancer was assessed by immunohistochemistry. Expression patterns were analyzed using an IP3R-1 antibody and correlated with clinicopathological data.</p><p><strong>Results: </strong>Immunohistochemical analysis revealed distinct patterns of IP3R-1 expression. IP3R-1 was consistently expressed within the basal layer of normal epidermis, but was absent in suprabasal cells. A marked increase in IP3R-1 expression was observed in atypical cells within dysplastic lesions. Furthermore, significant overexpression of IP3R-1 was evident in SCC and BCC, irrespective of histological subtype or differentiation. However, no correlation was found between IP3R-1 expression and clinicopathological features.</p><p><strong>Limitations: </strong>The findings lack confirmation through direct molecular assays and are based solely on immunohistochemical expression.</p><p><strong>Conclusion: </strong>These findings strongly suggest that IP3R-1 plays a significant role in the development and progression of skin cancer, with its altered expression observed early in carcinogenesis. Nevertheless, its expression does not correlate with typical clinical-pathological aspects of neoplasia.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"380-385"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sunil K Gupta, Sushantika Sushantika, Shivani Vashisht, Soumya Nanda
{"title":"An Intriguing Case of Extra-Digital Glomus Tumor on the Palm.","authors":"Sunil K Gupta, Sushantika Sushantika, Shivani Vashisht, Soumya Nanda","doi":"10.4103/idoj.idoj_1186_24","DOIUrl":"10.4103/idoj.idoj_1186_24","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"429-431"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Causality and Association: Two Terms to Use and Interpret Judiciously.","authors":"Himel Mondal","doi":"10.4103/idoj.idoj_275_25","DOIUrl":"10.4103/idoj.idoj_275_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"432-433"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145549313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of Clinico-demography and Impact on Quality of Life of Patients with Scalp Pruritus.","authors":"Amol Varshney, Paschal Dsouza, Priyank Rastogi, Jitender Arora","doi":"10.4103/idoj.idoj_436_25","DOIUrl":"10.4103/idoj.idoj_436_25","url":null,"abstract":"<p><strong>Background: </strong>Scalp pruritus is a common symptom in both dermatologic and nondermatologic conditions. Despite its prevalence, its clinico-demography and impact on quality of life (QoL) remain underexplored.</p><p><strong>Aim and objectives: </strong>This study aims to analyze the clinico-demography of scalp pruritus and its effect on the QoL of patients attending the dermatology department at a tertiary care institute.</p><p><strong>Patients and methods: </strong>An observational cross-sectional study was conducted over 18 months (July 2022 to January 2024). The sample size was 500, and patients were selected from the dermatology outpatient department. Demographics, etiology, pruritus severity (Visual Analog Scale), and QoL (using Dermatology Life Quality Index) were assessed.</p><p><strong>Results: </strong>The most common dermatological causes were seborrheic dermatitis (45.4%) and psoriasis (10.6%). Non-dermatologic causes included diabetes mellitus (8.2%) and post-herpetic neuralgia (5.4%). Moderate to very severe pruritus was reported by 54.6% of patients. A small effect on QoL was reported by 37.4% patients, and an extremely large effect by 12.8%.</p><p><strong>Limitations: </strong>The study was single-centered and relied on subjective assessments. Confounding factors like comorbidities and medications were not fully explored.</p><p><strong>Conclusion: </strong>Scalp pruritus significantly impacts patients' QoL. A multidisciplinary approach addressing both dermatologic and systemic causes is essential for effective management.</p>","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"361-366"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147672761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cryotherapy for Keloids Redefined: The Role of Injector Plate in Large Keloid Treatment.","authors":"Sumir Kumar, Avneet Kaur, Sameer Kaur","doi":"10.4103/idoj.idoj_520_25","DOIUrl":"10.4103/idoj.idoj_520_25","url":null,"abstract":"","PeriodicalId":13335,"journal":{"name":"Indian Dermatology Online Journal","volume":" ","pages":"459-460"},"PeriodicalIF":2.0,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147689460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}