Ibrahim Basol, Hatice Yazisiz, Hatice Deniz Ilhan, Ozlem Koyuncu Ozyurt, Betil Ozhak
{"title":"Could ocular demodicosis be a risk factor for punctal stenosis, dry eye, and blepharitis?","authors":"Ibrahim Basol, Hatice Yazisiz, Hatice Deniz Ilhan, Ozlem Koyuncu Ozyurt, Betil Ozhak","doi":"10.4103/IJO.IJO_2187_24","DOIUrl":"10.4103/IJO.IJO_2187_24","url":null,"abstract":"<p><strong>Purpose: </strong>Demodex, an ectoparasite, can threaten eye health by settling into different eyelash bases. It is particularly suggested to cause dysfunction in the Meibomian glands. This cross-sectional study aimed to investigate the relationships between ocular demodicosis, punctal stenosis, dry eye, and blepharitis.</p><p><strong>Methods: </strong>A total of 144 patients who presented to the Ophthalmology Clinic and volunteered to participate in the study were included. The demographic characteristics of the patients, presence of blepharitis, tear breakup time, eye-watering according to Munk's epiphora scoring, and punctal structures according to Kashkouli classification were recorded. Eyelash epilation was performed while preserving the root structure, and the eyelashes were examined under a light microscope. The relationship between Demodex presence and severity with punctal structure, dry eye status, and blepharitis was evaluated.</p><p><strong>Results: </strong>No significant relationship was found between punctal stenosis and Demodexspp. infestation in both eyes (P > 0.05). Overall, there was a statistical relationship between the presence of Demodexspp. settled in the eyelashes (right lower and upper, left upper eyelid lashes) and dry eye (P < 0.05), but there was no relationship with Demodex density (>3/eyelid). In eyes with blepharitis, especially in patients with anterior blepharitis, the presence and density of Demodexspp. were higher than in patients without blepharitis (P < 0.001 for the right upper, left lower, and upper eyelids, P = 0.001 for the right lower eyelid).</p><p><strong>Conclusion: </strong>Demodex infestations may be associated with blepharitis and dryness of eyes, but there is no association with punctal stenosis.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 4","pages":"603-609"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gaurav Chauhan, Suhita Mathimaaran, Ambika Chandrasekar, Varsha B Chavda, R Mugundhan, Bhaskar Srinivasan, Geetha Iyer, Murlidhar Rajagopalan, Shweta Agarwal
{"title":"Unpacking VKC: How gender and age shape the clinical picture.","authors":"Gaurav Chauhan, Suhita Mathimaaran, Ambika Chandrasekar, Varsha B Chavda, R Mugundhan, Bhaskar Srinivasan, Geetha Iyer, Murlidhar Rajagopalan, Shweta Agarwal","doi":"10.4103/IJO.IJO_177_25","DOIUrl":"10.4103/IJO.IJO_177_25","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate gender differences in childhood- and adult-onset vernal keratoconjunctivitis (VKC), as well as the variations between these onset groups.</p><p><strong>Methods: </strong>This was a retrospective, observational study (Jan 2015-Dec 2020). Electronic medical records of VKC patients managed by cornea specialists were analyzed based on their age of onset (<16 years for childhood [C-VKC], >16 years for adult [A-VKC]) and gender.</p><p><strong>Results: </strong>Out of 1018 VKC patients, 931 had childhood onset and 87 had adult onset. Both groups showed a male predominance; however, it was slightly less in A-VKC, with a mean follow-up of 28.6 ± 36.2 and 25.03 ± 40.3 months in C-VKC and A-VKC, respectively. A family history of allergies was observed only in C-VKC, with no gender differences. Asthma was more common in C-VKC, while skin allergies were more prevalent in A-VKC. Mixed VKC with Grade 4 severity was the most common in both age groups, with no gender differences in C-VKC; however, the limbal variant was more common in females with A-VKC. The proportion of A-VKC and C-VKC patients who developed complications was similar (P value 0.85). However, the C-VKC group had a significantly higher number of patients with multiple complications (P value 0.0076) as well as those requiring surgical intervention (P value 0.02). Keratoconus was the most common complication in both groups, but limbal stem cell deficiency was significantly higher in A-VKC across genders.</p><p><strong>Conclusion: </strong>Adult-onset VKC is a distinct condition with minor differences and a milder course compared to childhood-onset VKC. Notably, there are no significant gender-based differences in its clinical presentation or complications.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 4","pages":"594-598"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Murugesan Vanathi, Livia Khan, Thirumurthy Velpandian, Ashish Dubey, Noopur Gupta, Tulika Seth, Manoranjan Mahapatra, Maroof Ahmed Khan, Sandeep Jain, Radhika Tandon
{"title":"Adjunct Topical Human Immunoglobulin IgG Therapy in Dry Eye Disease.","authors":"Murugesan Vanathi, Livia Khan, Thirumurthy Velpandian, Ashish Dubey, Noopur Gupta, Tulika Seth, Manoranjan Mahapatra, Maroof Ahmed Khan, Sandeep Jain, Radhika Tandon","doi":"10.4103/IJO.IJO_608_25","DOIUrl":"10.4103/IJO.IJO_608_25","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study was to evaluate the role of topical human IgG eye drops (4 mg/mL) as adjunct therapy in eyes with moderate to severe refractory dry eye disease (DED).</p><p><strong>Methodology: </strong>A prospective, longitudinal, open label, dual cohort study of patients with chronic DED of moderate to severe grade comprise of OSIG therapy group cohort on topical immunoglobulin IgG 0.4% four times daily, as adjunctive therapy for one year, to study the role of OSIG therapy in comparison with conventional treatment. Patients above 18 years of age with chronic moderate to severe grade DED with tear break-up time (TBUT) ≤7 seconds, Schirmer test ≤9 mm/5 minutes, ocular surface disease index (OSDI) score ≥13, National Eye Institute (NEI) corneal staining score >3, and conjunctival staining score >3 were recruited into the study. Study participants in the conventional treatment cohort group were on topical lubricants four hourly (carboxymethyl cellulose 0.5% and lubricant ointment at bedtime), topical steroids (prednisolone 1%/fluorometholone 0.1%/loteprednol 0.5%) therapy as per the severity of the DED requirement and topical immunomodulators (cyclosporine A 0.1% eye drops or tacrolimus 0.1% eye ointment) twice daily. Study participants in the OSIG treatment cohort group were started on topical human immunoglobulin IgG 0.4% four times daily as adjunct therapy in addition to the all the above-mentioned medications for a period of 12 months. Study parameters included DED severity level assessment, NIH score, ocular surface evaluation tests, Schirmer's I test, TBUT, corneal and conjunctival staining score, OSDI score, and conjunctival hyperemia score. Ocular surface imaging using LipiView and ocular surface analyzer imaging for non-invasive TBUT (NITBUT), meibomian gland, and tear imaging was performed for the OSIG treatment cohort. Study characteristics were evaluated at time of recruitment into the study (baseline visit) and at serial follow-up of months 3, 6, and 12 in OSIG treatment group and follow-up at month 6 in conventional treatment group. Treatment grading score was devised in accordance to the frequency of application of lubricants and steroids and potency of steroids.</p><p><strong>Results: </strong>Our study of 71 eyes of 36 patients [mean age 39 ± 11.80 years] in OSIG treatment cohort group and 64 eyes of 32 patients [mean age 40 ± 11.53 years] in conventional treatment cohort group observed a significant reduction in the objective ocular surface symptom assessment parameters of OSDI scores, and dry eye severity level with improvement in clinical assessment parameters of TBUT, ocular surface staining scores, and conjunctival hyperemia grades in eyes on adjunct OSIG treatment cohort as compared to the conventional therapy cohort. The frequency of topical lubricants and steroids along with the potency of steroids used showed a decreasing trend with 45.28% noted to have become free of steroid dependence a","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 4","pages":"610-620"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143718764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sibel Ahmet, Murat Kocamaz, Cem Sarı, Ahmet Kırgız, Yusuf Yıldırım, Muhittin Taşkapılı
{"title":"The long-term effects of interface irrigation on visual outcomes and corneal aberrations in Small Incision Lenticule Extraction (SMILE).","authors":"Sibel Ahmet, Murat Kocamaz, Cem Sarı, Ahmet Kırgız, Yusuf Yıldırım, Muhittin Taşkapılı","doi":"10.4103/IJO.IJO_1856_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1856_24","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the long-term effects on visual outcomes and corneal aberrations of irrigating the interface during the small-incision lenticule extraction (SMILE) surgery for managing myopia and myopic astigmatism.</p><p><strong>Methods: </strong>In 47 patients who underwent bilateral SMILE surgery for myopia and myopic astigmatism, one eye was irrigated with 1.0 ml of balanced salt solution via cannula (Group 1) and the other eye was not irrigated (Group 2). Visual and refractive outcomes of 94 eyes were analyzed on the first day, first week, first month, sixth month, and first year. Preoperative and postoperative corneal higher-order aberrations (HOAs) obtained from Sirius corneal tomography (Costruzione Strumenti Oftalmici, Florence, Italy) were evaluated in both groups. Anterior segment optical coherence tomography (Heidelberg Spectralis; Heidelberg Engineering, Heidelberg, Germany) was used for interface evaluation on the first postoperative day. Intraoperative and postoperative complications were recorded.</p><p><strong>Results: </strong>Preoperative spherical, cylindrical, and spherical equivalent values were similar in both groups (P values: 0.913, 0.796, and 0.876, respectively). Statistically significant increases in mean HOAs and coma values were observed in both groups during the postoperative follow-up periods compared to the preoperative period (each P value <0.05). No significant differences were noted between the two groups concerning visual acuity, refractive values, and corneal aberrations throughout all postoperative follow-up periods (each P value >0.05). Epithelial inoculation developed in one eye in the irrigated group, and diffuse lamellar keratitis developed in one eye in the non-irrigated group.</p><p><strong>Conclusion: </strong>This study demonstrated that the visual, refractive, and wavefront aberration outcomes, both in the short and long term, were comparable between cases with and without interface irrigation following lenticule removal from the stromal pocket in SMILE surgery.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary implantation of glaucoma drainage device in secondary glaucoma: Comparison of Aurolab aqueous drainage implant versus Ahmed glaucoma valve.","authors":"Vanita Pathak-Ray","doi":"10.4103/IJO.IJO_2505_23","DOIUrl":"10.4103/IJO.IJO_2505_23","url":null,"abstract":"<p><p>Glaucoma drainage devices are invaluable in the management of secondary/ refractory glaucomas. This study aimed to compare the efficacy and safety of Aurolab Aqueous Drainage Implant (AADI) and the Ahmed Glaucoma Valve (AGV) in filtration-surgery-naïve secondary glaucoma eyes. For this purpose, a retrospective, comparative review was conducted on patients with secondary glaucoma (open and closed) who underwent primary tube procedures, either AADI or AGV. The primary outcome measure was intraocular pressure (IOP), and secondary measures included best-corrected visual acuity (BCVA), number of antiglaucoma medications (AGMs), and complications. This study included 59 eyes in the AADI group with a mean follow-up of 20.3 ± 12.9 months and 61 eyes in the AGV group with a mean follow-up of 19.8 ± 11.8 months. Preoperative IOP, AGM use, and BCVA did not significantly differ between the groups. However, at the last visit, both IOP and AGM use were significantly lower in the AADI group (12.9 ± 3.7 mmHg and 0.6 ± 0.9 vs. 15.7 ± 2.7 and 1.8 ± 1.0 respectively, all p < .001). Moreover, the AADI group exhibited a significantly higher rate of complete success (57.6%) compared to the AGV group (14.7%, p < .001); corresponding qualified success was 91.5% and 80.3%. Serious complication rates were comparable between the two groups. In conclusion, toth AADI and AGV procedures effectively reduced IOP and the need for AGMs. However, the reductions were significantly greater in the AADI group, which also showed a higher rate of complete success. Considering its affordability, AADI could have a substantial positive impact, particularly in resource-constrained settings.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"S327-S333"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142286156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Senthil Prasad, Tony A Koshy, R Sankarananthan, Logesh Balakrishnan, Kamatchi Nagu, Madhu Shekhar
{"title":"Effect of Nd:YAG laser posterior capsulotomy on higher order aberrations in different types of posterior capsule opacification: A prospective study.","authors":"R Senthil Prasad, Tony A Koshy, R Sankarananthan, Logesh Balakrishnan, Kamatchi Nagu, Madhu Shekhar","doi":"10.4103/IJO.IJO_3162_23","DOIUrl":"10.4103/IJO.IJO_3162_23","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate higher order aberrations (HOA) in different types of posterior capsule opacification (PCO) and analyze its changes following Nd:YAG laser posterior capsulotomy (LPC).</p><p><strong>Settings: </strong>Tertiary care ophthalmic hospital.</p><p><strong>Design: </strong>Prospective, comparative, observational study.</p><p><strong>Methods: </strong>One hundred ninety-three pseudophakic eyes with PCO were evaluated over 3 months. PCO was classified into pearly, fibrous, and mixed types. Their uncorrected visual acuity (UCVA), corrected distance visual acuity (CDVA), intraocular pressure (IOP), evaluation of posterior capsule opacification (EPCO) scoring and root mean square values of HOA (total, coma, spherical, and trefoil) were measured using a wavefront aberrometer before and after LPC.</p><p><strong>Results: </strong>Pearly, fibrous, and mixed PCO were observed in 89 (46.1%), 47 (24.4%), and 57 (29.5%) eyes respectively. The UCVA and CDVA showed improvement in all types of PCO post-procedure. The total HOA was 0.48 ± 0.47, 0.43 ± 0.42, 0.37 ± 0.34, and 0.76 ± 0.53, the coma aberrations were 0.18 ± 0.15, 0.18 ± 0.14, and 0.19 ± 0.19, spherical aberrations were 0.07 ± 0.12, 0.09 ± 0.12, and 0.05 ± 0.06, whereas the trefoil aberrations were 0.35 ± 0.44, 0.24 ± 0.26, and 0.21 ± 0.20, 15-day post-Nd:YAG LPC in pearly, fibrous, and mixed PCO respectively, all of which showed a significant reduction. The EPCO score showed no significant difference between different subtypes of PCO and had no correlation with the HOA.</p><p><strong>Conclusions: </strong>Post Nd:YAG LPC showed improvement in visual acuity with significant reduction in HOA in all types of PCO.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"370-376"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Demographic profile, management approaches, and outcome analysis of secondary childhood glaucoma in a tertiary eye care hospital in northern India.","authors":"Suneeta Dubey, Parul Bansal, Julie Pegu","doi":"10.4103/IJO.IJO_1595_24","DOIUrl":"10.4103/IJO.IJO_1595_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S345-S346"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12013321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fahri O Aydin, Burakhan K Aksoy, Ali Ceylan, Yusuf B Akbaş, Murat Karapapak, Burçin Kepez Yildiz, Yusuf Yildirim
{"title":"Comparison of two different intraocular lenses used in the modified Yamane technique.","authors":"Fahri O Aydin, Burakhan K Aksoy, Ali Ceylan, Yusuf B Akbaş, Murat Karapapak, Burçin Kepez Yildiz, Yusuf Yildirim","doi":"10.4103/IJO.IJO_2235_24","DOIUrl":"10.4103/IJO.IJO_2235_24","url":null,"abstract":"<p><strong>Purpose: </strong>To compare AcrySof MA60AC (Alcon Laboratories, Fort Worth, TX, USA) and Sensar AR40e (Johnson and Johnson, Santa Ana, CA, USA) used in Yamane sutureless scleral fixation technique in terms of visual acuity, refractive stability, and complications.</p><p><strong>Methods: </strong>A retrospective, cross-sectional study was conducted in Istanbul Başakşehir Çam and Sakura City Hospital. Patients were divided into two groups: The first group consisted of patients with MA60AC lenses, while the second group consisted of patients with AR40e. Aphakic patients who underwent secondary intraocular lens (IOL) implantation and had postoperative minimum 3-month follow-up records were included. Visual acuity, refractive outcomes, perioperative and postoperative complications were recorded.</p><p><strong>Results: </strong>Forty-nine patients were included in the study. Twenty-two patients were in the first group and 27 patients were in the second group. Age, gender, and follow-up time were similar between groups (P = 0.546, 0.213, and 0.347, respectively). The median lenticular astigmatism value was 0.86 (0.08-2.11) D in group 1 and 0.99 (0.31-2.96) D in group 2 (P = 0.898). There was no significant difference between groups in terms of visual acuity, spherical, cylindrical, and spherical equivalent values (P = 0.752, 0.375, 0.073, and 0.949, respectively). In group 1, a haptic tip fracture and optic-haptic separation were observed perioperatively. Optic-haptic junction separation was observed in one patient in group 1 on postoperative day 1. In group 1, epiretinal membrane development was significantly higher (P = 0.019).</p><p><strong>Conclusions: </strong>Both AcrySof MA60AC and Sensar AR40e IOLs via the modified Yamane technique yielded favorable and predictable outcomes. Although statistically insignificant, haptic problems were more common in the first group.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 3","pages":"416-421"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monalisa Mohapatra, Shailja Tibrewal, Samrat Chatterjee, Pradeep Agarwal, Chintan Shah, Rajat Kapoor, Anupam Sahoo, Pradhanya Sen, Veenu Maan, Sonu Arjun Shetty, Samir Sutar, Priya Goyal, Suma Ganesh
{"title":"Clinical spectrum of bilateral microspherophakia and risk factors associated with poor visual outcomes following lensectomy surgery - A multicentric study.","authors":"Monalisa Mohapatra, Shailja Tibrewal, Samrat Chatterjee, Pradeep Agarwal, Chintan Shah, Rajat Kapoor, Anupam Sahoo, Pradhanya Sen, Veenu Maan, Sonu Arjun Shetty, Samir Sutar, Priya Goyal, Suma Ganesh","doi":"10.4103/IJO.IJO_607_24","DOIUrl":"10.4103/IJO.IJO_607_24","url":null,"abstract":"<p><strong>Purpose: </strong>To study the clinical profile of patients with microspherophakia and the factors associated with poor vision following lensectomy surgery.</p><p><strong>Methods: </strong>A multicenter, retrospective, cross-sectional analysis was conducted from January 2010 to June 2022 on patients diagnosed with microspherophakia.</p><p><strong>Results: </strong>A total of 102 eyes from 51 patients were enrolled, of whom 24 (47.1%) were male and 27 (52.9%) were female. All patients presented with bilateral involvement. The most common presenting complaint was defective vision, affecting 98 (96.1%) eyes. Patients exhibited varying degrees of lenticular myopia, with a mean refractive error of -13.54 ± 11.92 D. Glaucoma was present in 36 (35.3%) eyes at presentation. Subluxation of the crystalline lens was observed in 50 (49.1%) eyes, dislocation of the lens into the anterior chamber in 24 (23.5%) eyes, and dislocation into the vitreous cavity in 4 (3.9%) eyes. Limbal or pars plana lensectomy was performed in 54 (52.9%) eyes. The mean corrected visual acuity improved from 1.05 ± 0.82 logMAR units to 0.82 ± 0.79 logMAR units after lensectomy ( P = 0.029). Poor postoperative visual acuity (less than 20/200) was associated with poor preoperative visual acuity ( P = 0.005), presence of glaucoma at the first visit ( P = 0.013), and intraocular pressure >30 mmHg ( P < 0.001).</p><p><strong>Conclusion: </strong>Microspherophakia is associated with high lenticular myopia, subluxation, and dislocation of the crystalline lens. Significant improvement in postoperative vision was observed after lensectomy. Factors associated with poor postoperative vision included poor preoperative corrected vision, presence of glaucoma, and high intraocular pressure.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"335-340"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of change in the contact of IOL with the posterior capsule with respect to the orientation of haptics of the IOL using intraoperative spectral domain optical coherence tomography.","authors":"Naren Shetty, Yash Patel, Reshma Ranade, Akash Jain, Raghav Narasimhan, Apurva Bansod, Rudy Nuijts","doi":"10.4103/IJO.IJO_348_24","DOIUrl":"10.4103/IJO.IJO_348_24","url":null,"abstract":"<p><strong>Purpose: </strong>To study change in the contact of intraocular lens (IOL) with the posterior capsule with respect to the vertical versus horizontal orientation of the haptic-optic junction of the IOL using intraoperative spectral domain optical coherence tomography (SD-OCT).</p><p><strong>Methods: </strong>Fifty eyes of 50 patients with senile immature cataract underwent topical phacoemulsification procedure with implantation of a monofocal IOL by a single experienced surgeon. The Rescan 700 SD-OCT system was used for intraoperative imaging. These patients were imaged using intraoperative SD-OCT after implantation of IOL, with the haptics oriented horizontally and then vertically.</p><p><strong>Results: </strong>The vertical height between the posterior surface of the lens capsule and the posterior surface of IOL reduced significantly when the haptics were oriented vertically compared to horizontal orientation. This difference was found on analyzing both vertical as well as horizontal axis scans.</p><p><strong>Conclusion: </strong>We found a greater contact between the posterior capsule and the posterior surface of IOL, with the haptic optic junction of the IOL oriented vertically. This study also suggests the need for newer toric IOL designs which allow vertical orientation of haptics, leading to better contact between IOL and the bag.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"396-400"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11994185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}