Indian Journal of Ophthalmology最新文献

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Comparison of three types of scleral fixation of the intraocular lens.
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI: 10.4103/IJO.IJO_1840_24
Zeeyoon Byun, Sungsoon Hwang, Mingui Kong
{"title":"Comparison of three types of scleral fixation of the intraocular lens.","authors":"Zeeyoon Byun, Sungsoon Hwang, Mingui Kong","doi":"10.4103/IJO.IJO_1840_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1840_24","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to compare the 1-year clinical outcomes of three scleral fixation techniques for intraocular lens (IOL) implantation: ab externo scleral fixation, trocar-cannula-based sutureless fixation (\"sutureless fixation\"), and four-point scleral fixation.</p><p><strong>Methods: </strong>This retrospective study evaluated 77 consecutive eyes treated with scleral fixation of the IOL. The ab externo method utilized conventional sutured techniques, while the trocar-cannula-based sutureless method was adapted from the \"Yamane\" technique, employing a wide-angle fundus lens to facilitate IOL manipulation in the vitreous cavity. The four-point fixation method involved a double-armed polypropylene suture and two 26-gauge needles to secure the four IOL haptics at four distinct sites. One-way analysis of variance (ANOVA) was used for statistical comparison between the groups.</p><p><strong>Results: </strong>The four-point fixation group exhibited superior best-corrected visual acuity compared to the sutureless and ab externo groups at 1 and 3 months postoperatively (P = 0.004 and P = 0.002, respectively), along with significantly less surgically induced astigmatism (P < 0.001). The sutureless group had the shortest operative time, while the ab externo group had the longest (P < 0.001). No instances of IOL iris capture occurred in the four-point group, while three cases (10.0%) were noted in the sutureless group.</p><p><strong>Conclusion: </strong>The four-point fixation technique provides significant benefits, including faster visual recovery, enhanced IOL stability, and lower surgically induced astigmatism (SIA) values. The sutureless technique provides the benefit of shorter operative times but does pose a risk of IOL capture in a limited number of cases.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 3","pages":"422-428"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of change in the orientation of intraocular lens in the bag using intraoperative spectral-domain optical coherence tomography before and after capsular tension ring implantation.
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI: 10.4103/IJO.IJO_347_24
Naren Shetty, Reshma Ranade, Akash Jain, Raghav Narasimhan, Yash Patel, Rudy Nuijts, Rohit Shetty
{"title":"Evaluation of change in the orientation of intraocular lens in the bag using intraoperative spectral-domain optical coherence tomography before and after capsular tension ring implantation.","authors":"Naren Shetty, Reshma Ranade, Akash Jain, Raghav Narasimhan, Yash Patel, Rudy Nuijts, Rohit Shetty","doi":"10.4103/IJO.IJO_347_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_347_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose is to study the change in the contact of the IOL with the posterior capsule using intraoperative SD-OCT before and after implantation of the CTR post implantation of the IOL in the capsular bag.</p><p><strong>Methods: </strong>A total of 51 eyes of 51 patients with senile immature cataract underwent topical phacoemulsification procedure with implantation of an extended depth of focus intraocular lens by a single experienced surgeon. The Rescan 700 SD-OCT system was used for intraoperative imaging. These patients were imaged using intraoperative SD-OCT after implantation of the IOL and before and after implantation of appropriate size of CTR. The vertical height between posterior surface of the lens capsule and the posterior surface of the IOL was measured and compared across 3 CTR sizes.</p><p><strong>Results: </strong>The vertical height between the posterior surface of the lens capsule and the posterior surface of the IOL reduced significantly post CTR implantation (P value < 0.001) in all three groups. The change in height after CTR implantation was seen highest with the CTR size 13 mm and lowest with CTR size 11 mm.</p><p><strong>Conclusion: </strong>Significant improvement of contact between the IOL and the posterior capsule was shown after implantation of the CTR. Larger the size CTR, more the contact of the IOL with the bag was shown.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 3","pages":"341-345"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Venom ophthalmia and acute angle closure glaucoma in capillary leak syndrome. 毒液性眼炎和毛细血管渗漏综合征急性闭角型青光眼。
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.4103/IJO.IJO_2220_24
Nagarajan Shastikaa, S Uma Maheswari, Rajkiran Rajasekar, Ashik Azad, Prasanna Venkatesh Ramesh
{"title":"Venom ophthalmia and acute angle closure glaucoma in capillary leak syndrome.","authors":"Nagarajan Shastikaa, S Uma Maheswari, Rajkiran Rajasekar, Ashik Azad, Prasanna Venkatesh Ramesh","doi":"10.4103/IJO.IJO_2220_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2220_24","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the incidence and management of acute angle-closure glaucoma (ACG) following venomous snakebites, along with its associated systemic complications, and to evaluate the importance of early detection and intervention in preventing long-term visual impairment.</p><p><strong>Design: </strong>Prospective interventional case series.</p><p><strong>Method: </strong>This study included patients admitted with venomous snakebites to a tertiary care hospital in rural Tamil Nadu, India, over four years (March 2019 to August 2023). All patients underwent both systemic and ocular assessments, regardless of their presenting symptoms. Ocular complications, particularly ACG, were managed with topical and systemic treatments. Data collected included demographic information, type of snakebite, systemic symptoms, treatment outcomes, and ocular findings.</p><p><strong>Results: </strong>Of the 126 patients admitted with venomous snakebites, 84 presented with neurotoxic bites and 42 with hematotoxic bites. Nine patients developed bilateral ACG, all of whom had sustained hematotoxic bites. Visual acuity (VA) ranged from hand motion to 6/9, with elevated intraocular pressure (IOP) ranging between 12 and 54 mm of Hg. Systemic complications included acute renal failure in 16 hematotoxic cases, with four patients requiring hemodialysis and subsequently succumbing to renal failure and multiorgan dysfunction. After treatment with antisnake venom, topical IOP-lowering agents, corticosteroids, and systemic therapies, five patients demonstrated full recovery, with normalized IOP and improved VA.</p><p><strong>Conclusion: </strong>ACG is a significant but underreported complication of hematotoxic snakebites. Early detection and intervention, including routine ocular screening, are crucial to prevent visual impairment. Ocular involvement may also serve as a prognostic indicator of severe systemic envenomation.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S298-S302"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-cost do-it-yourself (DIY) kit for glaucoma procedures. 用于青光眼手术的低成本 DIY 套件。
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-08-14 DOI: 10.4103/IJO.IJO_950_24
Indira Pegu, Rengaraj Venkatesh, Swati Upadhyaya
{"title":"Low-cost do-it-yourself (DIY) kit for glaucoma procedures.","authors":"Indira Pegu, Rengaraj Venkatesh, Swati Upadhyaya","doi":"10.4103/IJO.IJO_950_24","DOIUrl":"10.4103/IJO.IJO_950_24","url":null,"abstract":"<p><p>Surgical skill training in ophthalmology is pivotal for ensuring optimal and safe patient outcomes. Access to traditional training resources such as cadaveric or animal eyes, as well as modern alternatives such as silicone eyeballs and simulators, remains limited, especially in resource-constrained settings. We present a series of innovative and low-cost do-it-yourself (DIY) models for glaucoma training using readily available hospital waste materials. These models allow ophthalmic assistants, fellows, and junior consultants to practice various procedures before transitioning to live patients, thereby enhancing surgical proficiency and minimizing the financial burden on both trainees and training institutions. We were able to practice procedures such as tonometry, central corneal thickness measurement, laser suture lysis, laser iridotomy, anterior chamber decompression, bleb needling, trabeculectomy flap construction, and suturing. By providing a practical and easy training solution, these models have the potential to boost confidence among glaucoma trainees and thus address the growing demand for skilled glaucoma surgeons.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"S324-S326"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative evaluation of OCT with OCTA changes at the optic disc and macula in glaucoma suspect and early glaucoma. 比较评估青光眼疑似患者和早期青光眼患者视盘和黄斑的 OCT 与 OCTA 变化。
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2024-10-25 DOI: 10.4103/IJO.IJO_2575_23
Dewang Angmo, Anirudh Kapoor, Gazella B Warjri, Shorya Vardhan Azad, Rohan Chawla, Viney Gupta, Tanuj Dada
{"title":"Comparative evaluation of OCT with OCTA changes at the optic disc and macula in glaucoma suspect and early glaucoma.","authors":"Dewang Angmo, Anirudh Kapoor, Gazella B Warjri, Shorya Vardhan Azad, Rohan Chawla, Viney Gupta, Tanuj Dada","doi":"10.4103/IJO.IJO_2575_23","DOIUrl":"10.4103/IJO.IJO_2575_23","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the diagnostic ability of macular ganglion cell inner plexiform layer (mGCIPL) and peripapillary retinal nerve fiber layer (pRNFL) thickness on optical coherence tomography (OCT) and macular and peripapillary perfusion changes using OCT angiography (OCTA) in glaucoma suspect and early primary open angle glaucoma (POAG).</p><p><strong>Methods: </strong>Ninety patients (30 normal, 30 glaucoma suspects, and 30 early POAG) were recruited in this cross-sectional, prospective study. The average thickness of mGCIPL and pRNFL on spectral domain-OCT and macular vessel density (VD), optic nerve head (ONH) perfusion, and ONH flux index (FI) on OCTA were evaluated for early diagnosis of glaucoma.</p><p><strong>Results: </strong>Macular VD, ONH perfusion, and ONH FI were significantly reduced in early POAG eyes compared to normal. The best correlation was observed between ONH FI and the average RNFL in both glaucoma suspects ( r = 0.47, P < 0.01) and early POAG patients ( r = 0.53, P < 0.01). Out of all the measured OCTA parameters, only ONH perfusion was significantly lower in glaucomatous eyes compared to glaucoma suspects ( P < 0.001). Average GCIPL (0.82) and macular VD (0.76) had the highest area under the receiver operating characteristic (AUROC) curve value among all the OCT and OCTA parameters, respectively, for differentiating glaucoma suspects from controls. Rim area (0.92) and ONH FI (0.81) had the highest AUROC value among all the OCT and OCTA parameters for differentiating early POAG patients from controls.</p><p><strong>Conclusion: </strong>OCTA vascular parameters had a good correlation with structural damage both at the disc and the macula. OCT parameters were superior to OCTA parameters for diagnosis of glaucoma, although OCTA parameters are deranged very early in the disease.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":" ","pages":"S260-S266"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Early outcomes of bent ab interno needle goniectomy and Espaillat goniotomy with phacoemulsification in open-angle glaucoma.
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.4103/IJO.IJO_2078_24
Devendra Maheshwari, Madhavi Ramanatha Pillai, Shweta Ranjiv Dev, Nimrita Gyanchand Nagdev, Rengappa Ramakrishnan
{"title":"Early outcomes of bent ab interno needle goniectomy and Espaillat goniotomy with phacoemulsification in open-angle glaucoma.","authors":"Devendra Maheshwari, Madhavi Ramanatha Pillai, Shweta Ranjiv Dev, Nimrita Gyanchand Nagdev, Rengappa Ramakrishnan","doi":"10.4103/IJO.IJO_2078_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2078_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S352-S353"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bleb resuscitation of failing, leaking and dysfunctional blebs: A review. 失败、渗漏和功能障碍出血点的出血点复苏:综述。
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.4103/IJO.IJO_1233_24
Arshi Singh, Kirti Singh, Aastha Singh
{"title":"Bleb resuscitation of failing, leaking and dysfunctional blebs: A review.","authors":"Arshi Singh, Kirti Singh, Aastha Singh","doi":"10.4103/IJO.IJO_1233_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1233_24","url":null,"abstract":"<p><p>The success of trabeculectomy surgery depends on the longevity of the filtering bleb. Bleb failure can be categorized into two types: the scarred bleb with high intraocular pressure or the over-filtering and leaking bleb with low intraocular pressure. Bleb scarring is an insidious process over time as a consequence of excessive subconjunctival fibrosis. Timely recognition and early intervention utilizing a stepped-up approach are important for resuscitating the bleb and salvaging the trabeculectomy. Over-filtration and leaky bleb on the other end of the spectrum lead to failure of optimal bleb function and require a different management approach. This review discusses in detail various surgical techniques to revive dysfunctional blebs with a special focus on bleb needling. Timely identification and multifaceted management of bleb-related complications is the key to ultimately improving long-term success rates and patient outcomes.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S197-S206"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Modified ab-externo scleral fixation method for dislocated scleral fixated intraocular lenses.
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-26 DOI: 10.4103/IJO.IJO_1315_24
Ayushi Choudhary, Gaurang Sehgal, Chaitra Jayadev, Nagesha C Krishnappa
{"title":"Modified ab-externo scleral fixation method for dislocated scleral fixated intraocular lenses.","authors":"Ayushi Choudhary, Gaurang Sehgal, Chaitra Jayadev, Nagesha C Krishnappa","doi":"10.4103/IJO.IJO_1315_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_1315_24","url":null,"abstract":"<p><p>Sutured scleral fixation of intraocular lenses (SSFIOL) is a stable technique with a low risk of dislocation either from suture dehiscence (suture breakage or loosening) or suture erosion (suture degradation or wear), making it a reliable and durable option for intraocular lenses (IOL) fixation. Dislocation of rigid IOLs is managed conventionally by removing the IOL through a large sclerocorneal section and refixing the same lens or tucking another IOL into the sclera. The procedure described here is a modified ab-externo 4-exit 2-knot technique, wherein the dislocated SSFIOL can be refixated with a closed globe maneuver without removing the entire IOL. The eyelet of the haptic is exteriorized through a small limbal incision, and sutures are replaced at both ends. The IOLs refixated using this technique showed good centration postoperatively. Closed globe refixation of rigid IOLs can be easily performed with minimal or no complications. Minimal tissue handling and early postoperative recovery are advantages over conventional IOL removal and re-surgery.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 3","pages":"450-454"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143500625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "Outcomes of bent ab interno needle goniectomy with phacoemulsification in moderate to severe primary open angle glaucoma".
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.4103/IJO.IJO_2258_24
Zeba Khanam, Bhawesh Chandra Saha, Aditya Rajan
{"title":"Comment on \"Outcomes of bent ab interno needle goniectomy with phacoemulsification in moderate to severe primary open angle glaucoma\".","authors":"Zeba Khanam, Bhawesh Chandra Saha, Aditya Rajan","doi":"10.4103/IJO.IJO_2258_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2258_24","url":null,"abstract":"","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S347"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intraoperative tube placement in opaque corneas: The illuminated tube.
IF 2.1 4区 医学
Indian Journal of Ophthalmology Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.4103/IJO.IJO_2943_24
Arnav Panigrahi, Viney Gupta, Shikha Gupta
{"title":"Intraoperative tube placement in opaque corneas: The illuminated tube.","authors":"Arnav Panigrahi, Viney Gupta, Shikha Gupta","doi":"10.4103/IJO.IJO_2943_24","DOIUrl":"https://doi.org/10.4103/IJO.IJO_2943_24","url":null,"abstract":"<p><p>The role of glaucoma drainage devices (GDDs) for refractory glaucoma is well established because of certain advantages offered over conventional filtering surgeries. However, the correct plane of placement of the GDD tube inside an eye with an opaque cornea can be challenging, due to poor intra-operative visualization. These cases are also challenging if they undergo subsequent corneal grafting. In cases with presence of totally opaque cornea precluding tube visualization within the anterior chamber, we describe a novel technique for ensuring the correct positioning of a GDD tube.</p>","PeriodicalId":13329,"journal":{"name":"Indian Journal of Ophthalmology","volume":"73 Suppl 2","pages":"S339-S340"},"PeriodicalIF":2.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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