Indian journal of public health最新文献

{"title":"Burden of Sexually Transmitted Infections in Rajasthan, India: A Systematic Review and Meta-analysis.","authors":"Akhil Dhanesh Goel, Manoj Kumar Gupta, Neha Mantri, Shahzaad Hussain, S R Aswathy, Nitin Joshi, Shefaly Chaudhury, Prakash Narwani, Pankaj Bhardwaj","doi":"10.4103/ijph.ijph_1104_24","DOIUrl":"10.4103/ijph.ijph_1104_24","url":null,"abstract":"<p><strong>Background: </strong>There is a notable gap persisting in the existing body of evidence regarding the prevalence of sexually transmitted infections (STIs) in the general population in India.</p><p><strong>Objectives: </strong>The primary aim of this review is to provide a comprehensive assessment and quantification of the burden of STIs within the state of Rajasthan.</p><p><strong>Materials and methods: </strong>The study findings conformed to the criteria outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Two reviewers independently conducted an extensive search across multiple databases, which included PubMed, Scopus, Google Scholar, and Shodhganga, along with cross-referencing and manual searches. A standardized data extraction checklist was used to extract the data from the included studies. An appraisal tool for cross-sectional studies was used to assess the risk of bias. A random-effects meta-analysis model was utilized to estimate the pooled prevalence of syphilis among the blood donor population and the general population in Rajasthan.</p><p><strong>Results: </strong>A total of 2575 articles were screened, and 20 studies met the inclusion criteria. The burden of STI in the general population ranges from 2.2% to 9.09% (gonorrhea, n = 2 studies) and 16% (chlamydia, n = 1 study). Of these, 14 studies in blood donors revealed a pooled prevalence of syphilis as 0.04% (95% confidence interval [CI], 0.03%-0.05%). Similarly, in the general population, the pooled prevalence was found to be 0.05% (95% CI, 0.04-0.06).</p><p><strong>Conclusion: </strong>STIs are an important public health concern with a considerable burden in the population. This review underscores the significance of conducting STI surveillance to identify emerging trends to address specific STIs effectively. In addition, there was a gap in evidence reporting the prevalence of STIs other than syphilis.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S46-S53"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of HIV and Condom Use Practices among Female Sex Workers in West Bengal: Revisiting 2020 Behavioral Surveillance Surveys.","authors":"Debdutta Agasty, Rahul Biswas, Somnath Naskar, Debjit Chakraborty, Pankaj Kumar Khan, Alok Kumar Deb, Shanta Dutta","doi":"10.4103/ijph.ijph_1088_24","DOIUrl":"10.4103/ijph.ijph_1088_24","url":null,"abstract":"<p><strong>Background: </strong>Female sex workers (FSWs) constitute a significant portion of high-risk groups (HRGs) in the districts of West Bengal, as indicated by HRG size mapping exercises.</p><p><strong>Objectives: </strong>This study aimed to evaluate the knowledge of HIV/AIDS and condom usage practices among FSWs in clusters selected from districts in West Bengal for behavioural surveillance surveys (BSS)-lite.</p><p><strong>Materials and methods: </strong>BSS-lite was implemented in designated districts of West Bengal and interviews with 399 brothel and street-based FSWs from January to March 2020 were conducted utilizing computer-assisted personal interview or audio-computer assisted self-interview. Data analysis was performed using SPSS, version 17. Chi-square testing was employed to examine the association between HIV/AIDS knowledge and sociodemographic factors, service utilization, and condom usage behaviors.</p><p><strong>Results: </strong>The mean age of FSW respondents was 31 years (standard deviation 7.9) with a majority being illiterate (48.4%). Approximately 50.5% of FSWs were separated or divorced, and for 87.2% of respondents, sex work constituted their primary occupation. The percentage of comprehensive knowledge was 12.8%. There was a significant association ( P < 0.01) between condom use in the last sex act with frequency of condom use with commercial partner and condom use with regular partner.</p><p><strong>Conclusion: </strong>Enhanced interventions are warranted to address the knowledge gap concerning HIV transmission and condom use practices among FSWs, particularly with respect to regular partners.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S27-S31"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preparedness for Sexually Transmitted Infection Surveillance in India: The Role of Collaborative Efforts in Strengthening National Systems.","authors":"Sumathi Muralidhar, Abhishek Lachyan","doi":"10.4103/ijph.ijph_1113_24","DOIUrl":"10.4103/ijph.ijph_1113_24","url":null,"abstract":"<p><strong>Summary: </strong>Sexually transmitted infections are a major public health concern in India, particularly affecting high-risk groups, women and adolescents. The apex regional sexually transmitted disease center plays a key role in surveillance, offering testing, treatment, and data collection to guide national strategies. However, challenges such as stigma, limited healthcare access, underreporting, and resource constraints hinder effective control. India's large population and the prevalence of asymptomatic cases further complicate the issue. Key strategies for improvement include public awareness, expedited partner therapy, better healthcare access, and digital health solutions, with a focus on high-risk populations and stronger healthcare infrastructure.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S75-S77"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Human Immunodeficiency Virus Coinfection with Hepatitis B or Hepatitis C and its Sociodemographic Correlates among Prison Inmates of Northeast India.","authors":"Sanayaima Hanjabam, Victoria Loukrakpam, Tamphasana Thounaojam, Priyam Nidhi","doi":"10.4103/ijph.ijph_1110_24","DOIUrl":"10.4103/ijph.ijph_1110_24","url":null,"abstract":"<p><strong>Background: </strong>Human immunodeficiency virus (HIV) and hepatitis are common viral infections. Given sexual, blood, and perinatal transmission routes, HIV and hepatitis can be expected to be transmitted in similar at-risk populations. Roughly 10%-20% of HIV-infected patients are expected to have hepatitis B virus (HBV) coinfection.</p><p><strong>Materials and methods: </strong>This paper uses the data of 17 th round of HIV Sentinel Surveillance 2021 conducted in 5 prisons of Assam, Manipur, Mizoram, and Tripura. The 17 th round of HSS was implemented at 53 surveillance sites in prisons during 2020-21. Almost every district in the country has a HIV surveillance site for one or more of the risk groups. Five prison surveillance sites were included in this study from the state of Assam, Manipur, Mizoram, and Tripura.</p><p><strong>Results: </strong>In this study, the seroprevalence of HIV monoinfection among 1996 prison inmates was 1.5% (31), HBV monoinfection was 1.25% (25), Hepatitis C virus (HCV) monoinfection was 10.77% (215), HIV and HBV coinfection was 0.15% (3), HIV and HCV coinfection was 4.71% (94), HBV and HCV coinfection was 0.35(7) and HIV, and HBV and HCV coinfection was 0.25% (5).</p><p><strong>Conclusions: </strong>The HIV coinfection with HBV or HCV is high and a significant health threat in the prison inmates of Northeast India. Data suggest a high prevalence of HCV coinfection compared to HBV, despite the fact both viruses have common routes of transmission.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S10-S14"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Analysis of HIV Prevalence Trends among Antenatal Care Attendees and Associated Factors in Western India (2008-2021).","authors":"Prachi Ravindra Phadke, Aditi Jayant Kulkarni, Sheela V Godbole, Suvarna S Badekar, Garima Meena, Rashmi G Shinde","doi":"10.4103/ijph.ijph_1093_24","DOIUrl":"10.4103/ijph.ijph_1093_24","url":null,"abstract":"<p><strong>Background: </strong>Periodic monitoring of HIV prevalence among antenatal care (ANC) attendees and exploring the factors influencing its transmission is essential to get updated information on the HIV epidemic.</p><p><strong>Objectives: </strong>The objective of this study was to analyze HIV prevalence trends among ANC attendees in Western India from 2008 to 2021 and identify factors associated with HIV positivity in this population.</p><p><strong>Materials and methods: </strong>This secondary analysis utilized surveillance data from seven consecutive rounds of HIV sentinel surveillance among ANC attendees in Western India. Trends in HIV prevalence were calculated using the Mantel-Haenszel linear-by-linear χ 2 association test, and logistic regression was used to examine the factors associated with HIV positivity. Statistical analysis was done on IBM Corp. Released 2016. IBM SPSS Statistics for Windows, Version 24.0. (Armonk, NY: IBM Corp.).</p><p><strong>Results: </strong>HIV prevalence for ANC attendees was 0.4% in 2008 which significantly declined to 0.2% in 2021. Women with spouse/partner residing alone in another place/town (odds ratio [OR]: 1.78, 95% confidence interval [CI]: 1.42-2.23), spouse involved in local transport/truck driver/helper (OR: 1.89, 95% CI: 1.54-2.30), and spouse employed in hotel industry (OR: 1.71, 95% CI: 1.41-2.08) were the factors associated with HIV positivity. In the adolescent age group, the second gravida showed a significant increase in HIV prevalence from 0.0% in 2008 to 0.9% in 2021.</p><p><strong>Conclusion: </strong>The declining trend of HIV prevalence among ANC attendees in Western India highlights the effective program implementation. However, the identified factors associated with HIV positivity provide critical insights for focused preventive interventions.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S15-S20"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV Prevalence and Associated Risk Factors among Prisoners in South Indian States: Evidence from HIV Sentinel Surveillance 2019-2020.","authors":"Balasubramanian Ganesh, Aridoss Santhakumar, Jaganathasamy Nagaraj, Mathiyazhakan Malathi, Natesan Manikandan, Subasri Dhanusu, Arumugam Elangovan","doi":"10.4103/ijph.ijph_1092_24","DOIUrl":"10.4103/ijph.ijph_1092_24","url":null,"abstract":"<p><strong>Background: </strong>Prisoners are considered a high-risk group for HIV, and global data suggest a higher HIV prevalence among prisoners. HIV Sentinel Surveillance (HSS) was initiated as a biennial activity among prisoners in India in 2019 to monitor HIV prevalence levels and trends in Indian prisons.</p><p><strong>Objectives: </strong>The aim is to estimate the prevalence of HIV and syphilis and to assess the associated HIV risk behaviors among prisoners in South India.</p><p><strong>Materials and methods: </strong>HSS was a cross-sectional study design conducted in 12 central prisons across six southern states with a sample size of 400 for 3 months in 2019. Male prisoners aged 18 years and above were recruited through simple random sampling. Sociodemographic and behavioral data were collected, and HIV and syphilis testing was done.</p><p><strong>Results: </strong>A total of 4717 prisoners were included, and overall HIV prevalence was 1.1%, with higher prevalence in Telangana (3%) and Andhra Pradesh (1.9%). Marital status ever had sex in their lifetime, and syphilis positivity was significantly associated with higher HIV prevalence. More than 50% of the prisoners were never tested for HIV. About 1% ( n = 45) were injecting drug users, 81.5% had a regular female partner, and only 15% reported condom usage during their last sex.</p><p><strong>Conclusion: </strong>Higher HIV prevalence than the general population was observed. A significant proportion of the prisoners exhibited HIV risk behaviors and a major gap in availing of HIV testing and treatment services exists. The findings emphasize the urgent need to intensify HIV testing and IEC to facilitate impactful behavioral change communication.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S32-S38"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New HIV Infections among Primigravida Mothers in Southern India: Analysis from HIV Sentinel Surveillance (2015-2021).","authors":"Padmapriya Vallalnathan Mahalakshmi, Santhakumar Aridoss, Subasri Dhanusu, Nagaraj Jaganathasamy, Malathi Mathiyazhakan, Manikandan Natesan, Ganesh Balasubramanian, Arumugam Elangovan","doi":"10.4103/ijph.ijph_1094_24","DOIUrl":"10.4103/ijph.ijph_1094_24","url":null,"abstract":"<p><strong>Background: </strong>HIV Sentinel Surveillance (HSS) among pregnant women aged 15-49 serves as a key indicator for estimating HIV infection rates in the general population. Primigravida mothers represent the broader female demographic for assessing new HIV infections and determining HIV incidence among the female general population, as HIV transmission is predominantly through heterosexual routes in India.</p><p><strong>Objectives: </strong>This study aims to estimate the levels and trends of new infections among pregnant women in seven South Indian states and to understand the associated HIV risk factors.</p><p><strong>Materials and methods: </strong>HSS data from pregnant women attending ANC across seven South Indian states in 2015, 2017, 2019, and 2021 were analyzed. Based on inclusion criteria, a total of 182,066 records were analyzed. Multivariate logistic regression was used to determine the correlation between sociodemographic factors and the occurrence of new HIV cases.</p><p><strong>Results: </strong>A total of 470 (0.26%) new HIV infections were reported among all primigravida mothers, of which 74% ( n = 346) were aged between 15 and 24 years. Overall, the incidence among young primigravida mothers declined from 0.32% in 2015 to 0.20% in 2021. Age, education, and the occupation of the spouses were associated with the odds of new HIV infections Compared to 2019, the number of new HIV infections increased substantially in 2021 in the states of Andhra Pradesh, Karnataka, and Tamil Nadu, notably in 15-24-year age group.</p><p><strong>Conclusions: </strong>There is a need to investigate the transmission patterns of new infections in the general population, taking into account the varying trends among different states.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S39-S45"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated and Enhanced Surveillance and Epidemiology in India: Advancing the National HIV and Sexually Transmitted Infection Response.","authors":"Chinmoyee Das, Pradeep Kumar","doi":"10.4103/ijph.ijph_402_25","DOIUrl":"10.4103/ijph.ijph_402_25","url":null,"abstract":"","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S1-S2"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden of Sexually Transmitted Infections in Madhya Pradesh, India: A Systematic Review and Meta-analysis.","authors":"Pankaj Bhardwaj, Akhil Dhanesh Goel, Prasannajeet Bal, Abhishek Lohra, Vibha Joshi, Nitin Kumar Joshi, Manoj Kumar Gupta, Adarsh Mahesh Shukla, Shivani Vaidya, Nidhi Priyam","doi":"10.4103/ijph.ijph_1105_24","DOIUrl":"10.4103/ijph.ijph_1105_24","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections (STIs) pose a global public health threat, with over 30 pathogens known to spread sexually. In 2020, the World Health Organization reported 374 million new cases, with varied prevalence in India, especially among at-risk groups.</p><p><strong>Objectives: </strong>The objective of the study was to assess the prevalence of syphilis, chlamydia, and gonorrhea among the general population and blood donors in Madhya Pradesh.</p><p><strong>Materials and methods: </strong>Study findings adhered to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Two reviewers independently searched databases-PubMed, Scopus, Google Scholar, and ShodhGanga-along with manually checking references of included articles and systematic reviews. A standardized checklist guided data extraction. The risk of bias was assessed using the appraisal tool for cross-sectional studies tool for cross-sectional studies. Quantitative results were presented in a Forest plot via MetaXL software, using a random-effects meta-analysis model to estimate the pooled prevalence of syphilis among the general population and blood donors in Madhya Pradesh.</p><p><strong>Results: </strong>A review was conducted on 2943 articles to assess their eligibility. Seventeen studies met the inclusion criteria. The pooled prevalence of syphilis in seven studies involving the general population was found to be 0.4%, with a 95% confidence interval (CI) ranging from 0.1% to 0.7%. Studies on blood donors have a combined prevalence of 0.32% (95% CI, 0.25%-0.39%, n = 8 studies) in Madhya Pradesh.</p><p><strong>Conclusion: </strong>This review highlights STIs as an ongoing public health issue in Madhya Pradesh and underscores the need for surveillance to detect emerging patterns and address specific STIs effectively.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S54-S61"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Sexually Transmitted Infections (Syphilis, N. Gonorrhea, and Chlamydia) in Odisha and Andhra Pradesh: A Systematic Review and Meta-analysis.","authors":"Mili Roopchand Sahay, Kalolini D Samant, Arvind Kumar Singh, Subhakanta Sahu, Shivangi Das, Hrushikesh Das, Jitendriya Amrit Pritam, Sneha Pattanayak, Abhisek Mishra, Binod Kumar Patro, Baijayantimala Mishra, Sonu H Subba","doi":"10.4103/ijph.ijph_1099_24","DOIUrl":"10.4103/ijph.ijph_1099_24","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections (STIs) are a major global public health concern and are linked with human immunodeficiency virus in many ways. There is little evidence of the pooled prevalence of STIs across both states (Andhra Pradesh and Odisha).</p><p><strong>Objectives: </strong>Hence, we aim to estimate the prevalence of STIs in Andhra Pradesh and Odisha.</p><p><strong>Materials and methods: </strong>The protocol was registered in PROSPERO. A comprehensive search was done in PubMed, EBSCO, Cochrane Library, and Google Scholar. Studies were selected based on inclusion and exclusion criteria. Quality appraisal was done using the Joanna Briggs Institute tool. We used a standardized data extraction form to collect information from eligible studies. We did a random-effects meta-analysis to obtain the pooled prevalence of STI in Andhra Pradesh and Odisha. We stratified meta-analyses by states, microorganisms, and study setting.</p><p><strong>Results: </strong>We identified 1152 studies, of which 23 studies were included in the systematic review and 22 studies were included for meta-analysis. The pooled prevalence of Syphilis in Andhra Pradesh and Odisha was 0.01 (95% confidence interval [CI] 0.01-0.02) and 0.00 (95% CI 0.00-0.00), respectively. The pooled prevalence of Chlamydia and N. Gonorrhea in Andhra Pradesh among the general population was 0.01 (95% CI 0.00-0.03) and 0.05 (95% CI 0.01-0.24), respectively. The prevalence of Syphilis and Chlamydia among high-risk group populations in Andhra Pradesh was high in comparison with the general population.</p><p><strong>Conclusion: </strong>Understanding the prevalence of STIs in Andhra Pradesh and Odisha among the general population and high-risk group populations will strengthen the epidemiological data tracking and help in the effective management and control of STIs.</p>","PeriodicalId":13298,"journal":{"name":"Indian journal of public health","volume":"69 Suppl 1","pages":"S62-S70"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}