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Indian Journal of Clinical Biochemistry最新文献

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EZH2 Upregulates Notch Signaling Pathway Genes and Increases Cell Migration in Gastric Cancers EZH2 上调 Notch 信号通路基因并增加胃癌细胞迁移
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-08-08 DOI: 10.1007/s12291-024-01256-2
Hosseinali Ghazvini, M. Forghanifard, V. zarrinpour, Shiva Mirkalantari
{"title":"EZH2 Upregulates Notch Signaling Pathway Genes and Increases Cell Migration in Gastric Cancers","authors":"Hosseinali Ghazvini, M. Forghanifard, V. zarrinpour, Shiva Mirkalantari","doi":"10.1007/s12291-024-01256-2","DOIUrl":"https://doi.org/10.1007/s12291-024-01256-2","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141928572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validation of New Micro-spectrophotometric Method to Determine Diamine Oxidase Activity in Serum 验证测定血清中二胺氧化酶活性的新型微分光光度法
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-26 DOI: 10.1007/s12291-024-01253-5
Eser Yıldırım Sozmen, A. B. Sozmen
{"title":"Validation of New Micro-spectrophotometric Method to Determine Diamine Oxidase Activity in Serum","authors":"Eser Yıldırım Sozmen, A. B. Sozmen","doi":"10.1007/s12291-024-01253-5","DOIUrl":"https://doi.org/10.1007/s12291-024-01253-5","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141801375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Likelihood of a Novel Pathogenic LDLR Mutant Allele Inherited Preferentially within an Indian Family with Familial Hypercholesterolemia 在一个印度家族性高胆固醇血症家族中优先遗传新型致病性 LDLR 突变等位基因的可能性
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-25 DOI: 10.1007/s12291-024-01252-6
L. L. Reddy, Swarup A. V. Shah, Minal U. Paradkar, C. Ponde, R. Rajani, Sudhir Pillai, Dibyabhaba Pradhan, Harpreet Singh, T. Ashavaid
{"title":"Likelihood of a Novel Pathogenic LDLR Mutant Allele Inherited Preferentially within an Indian Family with Familial Hypercholesterolemia","authors":"L. L. Reddy, Swarup A. V. Shah, Minal U. Paradkar, C. Ponde, R. Rajani, Sudhir Pillai, Dibyabhaba Pradhan, Harpreet Singh, T. Ashavaid","doi":"10.1007/s12291-024-01252-6","DOIUrl":"https://doi.org/10.1007/s12291-024-01252-6","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141803648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitamin D in Disease Prevention and Cure-Part I: An Update on Molecular Mechanism and Significance on Human Health 维生素 D 在疾病预防和治疗中的作用--第一部分：分子机制和对人类健康影响的最新进展
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-22 DOI: 10.1007/s12291-024-01251-7
Shailendra Dwivedi, Vijay Singh, Aniruddha Sen, Dharamveer Yadav, Ruchika Agrawal, Surekha Kishore, Sanjeev Misra, Praveen Sharma
{"title":"Vitamin D in Disease Prevention and Cure-Part I: An Update on Molecular Mechanism and Significance on Human Health","authors":"Shailendra Dwivedi, Vijay Singh, Aniruddha Sen, Dharamveer Yadav, Ruchika Agrawal, Surekha Kishore, Sanjeev Misra, Praveen Sharma","doi":"10.1007/s12291-024-01251-7","DOIUrl":"https://doi.org/10.1007/s12291-024-01251-7","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141815612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality 心力衰竭患者可溶性尿激酶促血浆蛋白酶原激活剂受体的增加与疾病严重程度和心脏病死亡率有关
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-11 DOI: 10.1007/s12291-024-01249-1
Judit Gonda, Nisrine Aaddi, Sylvie Ahn, Michel Rousseau, Damien Gruson
{"title":"The Increase of Soluble Urokinase Plasminogen Activator Receptor in Heart Failure is Related to Disease Severity and Cardiac Mortality","authors":"Judit Gonda, Nisrine Aaddi, Sylvie Ahn, Michel Rousseau, Damien Gruson","doi":"10.1007/s12291-024-01249-1","DOIUrl":"https://doi.org/10.1007/s12291-024-01249-1","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome 细胞因子信号抑制因子 1 (SOCS1) 基因变异对多囊卵巢综合征的影响
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-10 DOI: 10.1007/s12291-024-01248-2
Niloufar Rakhshanizade, Saman Sargazi, M. Karajibani, Mahdi Majidpour, Atena Karajibani, F. Montazerifar, Marzieh Ghasemi
{"title":"Influence of Suppressor of Cytokine Signaling 1 (SOCS1) Gene Variations on Polycystic Ovary Syndrome","authors":"Niloufar Rakhshanizade, Saman Sargazi, M. Karajibani, Mahdi Majidpour, Atena Karajibani, F. Montazerifar, Marzieh Ghasemi","doi":"10.1007/s12291-024-01248-2","DOIUrl":"https://doi.org/10.1007/s12291-024-01248-2","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141658808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy 结肠癌细胞分泌 IL-6 和 TGF-β2 可能会增强对化疗的抵抗力
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-02 DOI: 10.1007/s12291-024-01247-3
Sruthi Sritharan, Nageswaran Sivalingam
{"title":"Secretion of IL-6 and TGF-β2 by Colon Cancer Cells May Promote Resistance to Chemotherapy","authors":"Sruthi Sritharan, Nageswaran Sivalingam","doi":"10.1007/s12291-024-01247-3","DOIUrl":"https://doi.org/10.1007/s12291-024-01247-3","url":null,"abstract":"","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141687119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia. 评估急性和慢性白血病患者的骨转换标志物
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-01 Epub Date: 2023-03-03 DOI: 10.1007/s12291-023-01124-5
Reem A Al-Qaisi, Abdulnasser M Al-Gebori, Mohammed Hadi Munshed Alosami
{"title":"Evaluation of Bone Turnover Markers in Patients with Acute and Chronic Leukemia.","authors":"Reem A Al-Qaisi, Abdulnasser M Al-Gebori, Mohammed Hadi Munshed Alosami","doi":"10.1007/s12291-023-01124-5","DOIUrl":"10.1007/s12291-023-01124-5","url":null,"abstract":"<p><p>This study investigated different bone biomarkers (cross-linked carboxy-terminal telopeptide of type 1 collagen (CTX-1), pyridinoline (PYD), osteocalcin (OC), interleukin-6 receptor (IL-6R), calcium (Ca), and magnesium (Mg)) in terms of their metabolism in 4 different leukemia subtypes (ALL, AML, CLL and CML). The design was case control study with 30 controls and 60 cases of leukemia patients. Authors have reported many results regarding decrease as well as increase of specific bone biomarker under investigation with each leukemia subtype when compared to control. In addition, Authors reported correlations between each biomarker level and leukemia subtypes.</p>","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78405447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Urine Metabolomics Reveals Overlapping Metabolic Associations Between Preeclampsia and Gestational Diabetes. 尿液代谢组学揭示先兆子痫与妊娠糖尿病之间重叠的代谢关系
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-01 Epub Date: 2022-12-06 DOI: 10.1007/s12291-022-01103-2
Nupur Rani Agarwal, Garima Kachhawa, Bolaji Fatai Oyeyemi, Neel Sarovar Bhavesh
{"title":"Urine Metabolomics Reveals Overlapping Metabolic Associations Between Preeclampsia and Gestational Diabetes.","authors":"Nupur Rani Agarwal, Garima Kachhawa, Bolaji Fatai Oyeyemi, Neel Sarovar Bhavesh","doi":"10.1007/s12291-022-01103-2","DOIUrl":"10.1007/s12291-022-01103-2","url":null,"abstract":"<p><p>Pregnancy is associated with numerous metabolic adaptations to meet the demands of the growing foetus. These adaptations could be perturbed during pregnancy due to preeclampsia (PE) and gestational diabetes (GDM). As these two obstetric aliments show some overlapping pathophysiology and similar biochemical dysregulation, the present study was undertaken to compare urine metabolome of PE and GDM with normal pregnancy (NT) in all trimesters of gestation using nuclear magnetic resonance spectroscopy-based metabolomics analysis to ascertain and compare metabolome in the study groups. We observed overlapping metabolic perturbations in PE and GDM. Though a study with a small sample size, this is the first report which confirms significantly differential metabolites in urine of both PE and GDM. Dimethylglycine and oxoglutaric acid were decreased while benzoic acid was increased in both the cases in all trimesters. Alanine, aspartate and glutamate metabolism, aminoacyl-tRNA biosynthesis, citrate and butanoate metabolism were the most perturbed pathways in both PE and GDM across pregnancy. These pathways have an association with energy metabolism, glucose homeostasis, insulin sensitivity and oxidative stress which play an important role in the development and progression of PE and GDM. In conclusion, our study showed that urine metabolome could reflect metabolic associations between PE and GDM and also in the identification of biomolecules that could be used as potential biomarker(s) for early detection of the metabolic diseases in pregnancy.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12291-022-01103-2.</p>","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239642/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86395513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Noninvasive Biomarkers for Alcohol-Related Liver Disease-A Proteomic Related Preliminary Report. 酒精相关肝病的无创生物标志物--蛋白质组学相关初步报告
IF 1.5
Indian Journal of Clinical Biochemistry Pub Date : 2024-07-01 Epub Date: 2023-03-03 DOI: 10.1007/s12291-023-01120-9
Prabhudas Nelaturi, Sangeetha P Kademani, Vithiavathi Siva Subramanian, Sambandam Ravikumar
{"title":"Noninvasive Biomarkers for Alcohol-Related Liver Disease-A Proteomic Related Preliminary Report.","authors":"Prabhudas Nelaturi, Sangeetha P Kademani, Vithiavathi Siva Subramanian, Sambandam Ravikumar","doi":"10.1007/s12291-023-01120-9","DOIUrl":"10.1007/s12291-023-01120-9","url":null,"abstract":"<p><p>Increased alcohol intake over decades leads to progressive alcohol-related liver disease (ALD) and contributes to increased mortality. It is characterized by reduced platelet count. Platelets have a role in protecting vascular integrity and involved in liver regeneration. Alcohol affects the platelet count and its function. Platelet function is regulated by their proteins, released during pathophysiological conditions. Therefore, platelet proteome plays a vital role during ALD. This preliminary study consists of 10 patients with ALD. It includes the preparation of human platelets for the proteomic approach. We performed liquid chromatography-mass spectrometry for the samples. A total of 536 proteins were identified in patients with ALD of which 31 proteins were mentioned as a candidate based on their clinical significance. The advancement of diagnostic or therapeutic tools based on the application of platelet proteins in ALD is still far off. Platform for platelet and its proteome research may give diagnostic and prognostic insights into ALD. Platelet proteomes could possibly be concluded as therapeutic and potential diagnostic or prognostic markers in ALD.</p><p><strong>Supplementary information: </strong>The online version contains supplementary material available at 10.1007/s12291-023-01120-9.</p>","PeriodicalId":13280,"journal":{"name":"Indian Journal of Clinical Biochemistry","volume":null,"pages":null},"PeriodicalIF":1.5,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239637/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81921524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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