IEEE Transactions on Biomedical Circuits and Systems最新文献_第5页

An Energy-Efficient and Scalable Deep Learning/Inference Processor With Tetra-Parallel MIMD Architecture for Big Data Applications 面向大数据应用的四并行MIMD架构节能可扩展深度学习/推理处理器

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2504563

Seongwook Park, Junyoung Park, Kyeongryeol Bong, Dongjoo Shin, Jinmook Lee, Sungpill Choi, H. Yoo

{"title":"An Energy-Efficient and Scalable Deep Learning/Inference Processor With Tetra-Parallel MIMD Architecture for Big Data Applications","authors":"Seongwook Park, Junyoung Park, Kyeongryeol Bong, Dongjoo Shin, Jinmook Lee, Sungpill Choi, H. Yoo","doi":"10.1109/TBCAS.2015.2504563","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2504563","url":null,"abstract":"Deep Learning algorithm is widely used for various pattern recognition applications such as text recognition, object recognition and action recognition because of its best-in-class recognition accuracy compared to hand-crafted algorithm and shallow learning based algorithms. Long learning time caused by its complex structure, however, limits its usage only in high-cost servers or many-core GPU platforms so far. On the other hand, the demand on customized pattern recognition within personal devices will grow gradually as more deep learning applications will be developed. This paper presents a SoC implementation to enable deep learning applications to run with low cost platforms such as mobile or portable devices. Different from conventional works which have adopted massively-parallel architecture, this work adopts task-flexible architecture and exploits multiple parallelism to cover complex functions of convolutional deep belief network which is one of popular deep learning/inference algorithms. In this paper, we implement the most energy-efficient deep learning and inference processor for wearable system. The implemented 2.5 mm ×4.0 mm deep learning/inference processor is fabricated using 65 nm 8-metal CMOS technology for a battery-powered platform with real-time deep inference and deep learning operation. It consumes 185 mW average power, and 213.1 mW peak power at 200 MHz operating frequency and 1.2 V supply voltage. It achieves 411.3 GOPS peak performance and 1.93 TOPS/W energy efficiency, which is 2.07× higher than the state-of-the-art.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"9 1","pages":"838-848"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2504563","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 37

A Smart CMOS Assay SoC for Rapid Blood Screening Test of Risk Prediction 用于风险预测的快速血液筛查试验的智能CMOS分析SoC

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2507618

Po-Hung Kuo, Jui-Chang Kuo, Hsiao-Ting Hsueh, J. Hsieh, Yi-Chun Huang, Tao Wang, Yen-Hung Lin, Chih-Ting Lin, Yao-Joe Yang, Shey-Shi Lu

引用次数: 10

A Circadian and Cardiac Intraocular Pressure Sensor for Smart Implantable Lens 用于智能植入式晶体的昼夜节律和心脏眼内压传感器

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2501320

A. Donida, G. Dato, Paolo Cunzolo, M. Sala, Filippo Piffaretti, P. Orsatti, D. Barrettino

引用次数: 34

Miniaturizing Ultrasonic System for Portable Health Care and Fitness 用于便携式医疗保健和健身的微型化超声系统

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2508439

Hao-Yen Tang, D. Seo, Utkarsh Singhal, Xi Li, M. Maharbiz, E. Alon, B. Boser

引用次数: 37

A 9 MHz–2.4 GHz Fully Integrated Transceiver IC for a Microfluidic-CMOS Platform Dedicated to Miniaturized Dielectric Spectroscopy 微型介电光谱专用微流控cmos平台的9mhz - 2.4 GHz全集成收发器IC

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2501816

M. Bakhshiani, M. Suster, P. Mohseni

{"title":"A 9 MHz–2.4 GHz Fully Integrated Transceiver IC for a Microfluidic-CMOS Platform Dedicated to Miniaturized Dielectric Spectroscopy","authors":"M. Bakhshiani, M. Suster, P. Mohseni","doi":"10.1109/TBCAS.2015.2501816","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2501816","url":null,"abstract":"This paper presents a fully integrated transceiver IC as part of a self-sustained, microfluidic-CMOS platform for miniaturized dielectric spectroscopy (DS) from MHz to GHz. Fabricated in AMS 0.35 μm 2P/4M RF CMOS, the transmitter (TX) part of the IC generates a single-tone sinusoidal signal with frequency tunability in the range of to excite a three-dimensional (3D), parallel-plate, capacitive sensor with a floating electrode and 9 μL microfluidic channel for sample delivery. With a material-under-test (MUT) loaded into the sensor, the receiver (RX) part of the IC employs broadband frequency response analysis (bFRA) methodology to measure the amplitude and phase of the RF excitation signal after transmission through the sensor. A one-time, 6-point sensor calibration algorithm then extracts both the real and imaginary parts of the MUT complex permittivity, εr, from IC measurements of the sensor transmission characteristics in the voltage domain. The “sensor + IC” is fully capable of differentiating among de-ionized (DI) water, phosphate-buffered saline (PBS), and alcoholic beverages in tests conducted at four excitation frequencies of ~ 50 MHz, 500 MHz, 1.5 GHz, and 2.4 GHz generated by the TX. Moreover, permittivity readings of PBS by the sensor interfaced with the IC at six excitation frequencies in the range of are in excellent agreement (rms error of 1.7% (real) and 7.2% (imaginary)) with those from bulk-solution reference measurements by commercial benchtop equipment. The total power consumption of the IC is with 1.5 V (analog) and 3.3 V (digital) supplies.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"9 1","pages":"849-861"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2501816","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62965229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Reconfigurable Resonant Regulating Rectifier With Primary Equalization for Extended Coupling- and Loading-Range in Bio-Implant Wireless Power Transfer 可重构谐振调节整流器与初级均衡扩展耦合和负载范围在生物植入物无线电力传输

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2503418

Xing Li, Xiaodong Meng, C. Tsui, W. Ki

{"title":"Reconfigurable Resonant Regulating Rectifier With Primary Equalization for Extended Coupling- and Loading-Range in Bio-Implant Wireless Power Transfer","authors":"Xing Li, Xiaodong Meng, C. Tsui, W. Ki","doi":"10.1109/TBCAS.2015.2503418","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2503418","url":null,"abstract":"Wireless power transfer using reconfigurable resonant regulating ( R3) rectification suffers from limited range in accommodating varying coupling and loading conditions. A primary-assisted regulation principle is proposed to mitigate these limitations, of which the amplitude of the rectifier input voltage on the secondary side is regulated by accordingly adjusting the voltage amplitude Veq on the primary side. A novel current-sensing method and calibration scheme track Veq on the primary side. A ramp generator simultaneously provides three clock signals for different modules. Both the primary equalizer and the R3 rectifier are implemented as custom integrated circuits fabricated in a 0.35 μm CMOS process, with the global control implemented in FPGA. Measurements show that with the primary equalizer, the workable coupling and loading ranges are extended by 250% at 120 mW load and 300% at 1.2 cm coil distance compared to the same system without the primary equalizer. A maximum rectifier efficiency of 92.5% and a total system efficiency of 62.4% are demonstrated.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"9 1","pages":"875-884"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2503418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 43

A Wearable EEG-HEG-HRV Multimodal System With Simultaneous Monitoring of tES for Mental Health Management 一种可穿戴的EEG-HEG-HRV多模态系统，同时监测tES用于心理健康管理

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2504959

U. Ha, Yongsu Lee, Hyunki Kim, Taehwan Roh, Joonsung Bae, Changhyeon Kim, H. Yoo

{"title":"A Wearable EEG-HEG-HRV Multimodal System With Simultaneous Monitoring of tES for Mental Health Management","authors":"U. Ha, Yongsu Lee, Hyunki Kim, Taehwan Roh, Joonsung Bae, Changhyeon Kim, H. Yoo","doi":"10.1109/TBCAS.2015.2504959","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2504959","url":null,"abstract":"A multimodal mental management system in the shape of the wearable headband and earplugs is proposed to monitor electroencephalography (EEG), hemoencephalography (HEG) and heart rate variability (HRV) for accurate mental health monitoring. It enables simultaneous transcranial electrical stimulation (tES) together with real-time monitoring. The total weight of the proposed system is less than 200 g. The multi-loop low-noise amplifier (MLLNA) achieves over 130 dB CMRR for EEG sensing and the capacitive correlated-double sampling transimpedance amplifier (CCTIA) has low-noise characteristics for HEG and HRV sensing. Measured three-physiology domains such as neural, vascular and autonomic domain signals are combined with canonical correlation analysis (CCA) and temporal kernel canonical correlation analysis (tkCCA) algorithm to find the neural-vascular-autonomic coupling. It supports highly accurate classification with the 19% maximum improvement with multimodal monitoring. For the multi-channel stimulation functionality, after-effects maximization monitoring and sympathetic nerve disorder monitoring, the stimulator is designed as reconfigurable. The 3.37 × 2.25 mm 2 chip has 2-channel EEG sensor front-end, 2-channel NIRS sensor front-end, NIRS current driver to drive dual-wavelength VCSEL and 6-b DAC current source for tES mode. It dissipates 24 mW with 2 mA stimulation current and 5 mA NIRS driver current.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"9 1","pages":"758-766"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2504959","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62966141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 53

A PWM Buck Converter With Load-Adaptive Power Transistor Scaling Scheme Using Analog-Digital Hybrid Control for High Energy Efficiency in Implantable Biomedical Systems 基于模数混合控制的负载自适应功率晶体管缩放PWM降压变换器在植入式生物医学系统中的高能效

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2501304

Sung-Yun Park, Jihyun Cho, Kyuseok Lee, E. Yoon

{"title":"A PWM Buck Converter With Load-Adaptive Power Transistor Scaling Scheme Using Analog-Digital Hybrid Control for High Energy Efficiency in Implantable Biomedical Systems","authors":"Sung-Yun Park, Jihyun Cho, Kyuseok Lee, E. Yoon","doi":"10.1109/TBCAS.2015.2501304","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2501304","url":null,"abstract":"We report a pulse width modulation (PWM) buck converter that is able to achieve a power conversion efficiency (PCE) of >80% in light loads (<;100 μA) for implantable biomedical systems. In order to achieve a high PCE for the given light loads, the buck converter adaptively reconfigures the size of power PMOS and NMOS transistors and their gate drivers in accordance with load currents, while operating at a fixed frequency of 1 MHz. The buck converter employs the analog-digital hybrid control scheme for coarse/fine adjustment of power transistors. The coarse digital control generates an approximate duty cycle necessary for driving a given load and selects an appropriate width of power transistors to minimize redundant power dissipation. The fine analog control provides the final tuning of the duty cycle to compensate for the error from the coarse digital control. The mode switching between the analog and digital controls is accomplished by a mode arbiter which estimates the average of duty cycles for the given load condition from limit cycle oscillations (LCO) induced by coarse adjustment. The fabricated buck converter achieved a peak efficiency of 86.3% at 1.4 mA and >80% efficiency for a wide range of load conditions from 45 μA to 4.1 mA, while generating 1 V output from 2.5-3.3 V supply. The converter occupies 0.375 mm2 in 0.18 μm CMOS processes and requires two external components: 1.2 μF capacitor and 6.8 μH inductor.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"9 1","pages":"885-895"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2501304","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62965180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

A Multi-Modality CMOS Sensor Array for Cell-Based Assay and Drug Screening 用于细胞检测和药物筛选的多模态CMOS传感器阵列

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-12-01 DOI: 10.1109/TBCAS.2015.2504984

T. Chi, Jong Seok Park, J. Butts, Tracy A. Hookway, Amy Su, Chengjie Zhu, Mark P. Styczynski, T. McDevitt, Hua Wang

{"title":"A Multi-Modality CMOS Sensor Array for Cell-Based Assay and Drug Screening","authors":"T. Chi, Jong Seok Park, J. Butts, Tracy A. Hookway, Amy Su, Chengjie Zhu, Mark P. Styczynski, T. McDevitt, Hua Wang","doi":"10.1109/TBCAS.2015.2504984","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2504984","url":null,"abstract":"In this paper, we present a fully integrated multi-modality CMOS cellular sensor array with four sensing modalities to characterize different cell physiological responses, including extracellular voltage recording, cellular impedance mapping, optical detection with shadow imaging and bioluminescence sensing, and thermal monitoring. The sensor array consists of nine parallel pixel groups and nine corresponding signal conditioning blocks. Each pixel group comprises one temperature sensor and 16 tri-modality sensor pixels, while each tri-modality sensor pixel can be independently configured for extracellular voltage recording, cellular impedance measurement (voltage excitation/current sensing), and optical detection. This sensor array supports multi-modality cellular sensing at the pixel level, which enables holistic cell characterization and joint-modality physiological monitoring on the same cellular sample with a pixel resolution of 80 μm×100 μm. Comprehensive biological experiments with different living cell samples demonstrate the functionality and benefit of the proposed multi-modality sensing in cell-based assay and drug screening.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"63 1","pages":"801-814"},"PeriodicalIF":5.1,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2504984","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62965692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 57

A Hybrid Semi-Digital Transimpedance Amplifier With Noise Cancellation Technique for Nanopore-Based DNA Sequencing 用于纳米孔DNA测序的混合半数字跨阻放大器与噪声消除技术

IF 5.1 2区医学

IEEE Transactions on Biomedical Circuits and Systems Pub Date : 2015-11-19 DOI: 10.1109/TBCAS.2015.2496232

Chung-Lun Hsu, Haowei Jiang, A. Venkatesh, D. Hall

{"title":"A Hybrid Semi-Digital Transimpedance Amplifier With Noise Cancellation Technique for Nanopore-Based DNA Sequencing","authors":"Chung-Lun Hsu, Haowei Jiang, A. Venkatesh, D. Hall","doi":"10.1109/TBCAS.2015.2496232","DOIUrl":"https://doi.org/10.1109/TBCAS.2015.2496232","url":null,"abstract":"Over the past two decades, nanopores have been a promising technology for next generation deoxyribonucleic acid (DNA) sequencing. Here, we present a hybrid semi-digital transimpedance amplifier (HSD-TIA) to sense the minute current signatures introduced by single-stranded DNA (ssDNA) translocating through a nanopore, while discharging the baseline current using a semi-digital feedback loop. The amplifier achieves fast settling by adaptively tuning a DC compensation current when a step input is detected. A noise cancellation technique reduces the total input-referred current noise caused by the parasitic input capacitance. Measurement results show the performance of the amplifier with 31.6 M Ω mid-band gain, 950 kHz bandwidth, and 8.5 fA/ √Hz input-referred current noise, a 2× noise reduction due to the noise cancellation technique. The settling response is demonstrated by observing the insertion of a protein nanopore in a lipid bilayer. Using the nanopore, the HSD-TIA was able to measure ssDNA translocation events.","PeriodicalId":13151,"journal":{"name":"IEEE Transactions on Biomedical Circuits and Systems","volume":"29 1","pages":"652-661"},"PeriodicalIF":5.1,"publicationDate":"2015-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/TBCAS.2015.2496232","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"62965047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 25