Hypertension Research最新文献_第9页

Association between urinary cotinine levels and hypertensive disorders of pregnancy in women with uterine fibrosis. 尿可替宁水平与子宫纤维化妇女妊娠期高血压疾病的关系

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02051-5

Satoshi Morimoto, Atsuhiro Ichihara

引用次数: 0

Inter-twin growth discordance in monochorionic twins as a novel risk factor for preeclampsia. 单绒毛膜双胞胎的双胞胎间生长不一致是子痫前期的一个新的危险因素。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02047-1

Akihide Ohkuchi

引用次数: 0

Hypertension awareness, treatment, control, and prognosis: insights from the sub-cohort of China PEACE million persons project. 高血压的认识、治疗、控制和预后：来自中国和平百万人口项目亚队列的见解。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02037-3

Weida Qiu, Anping Cai, Shiping Wu, Yanchen Zhu, He Zheng, Zhiqiang Nie, Jiabin Wang, Yingqing Feng

{"title":"Hypertension awareness, treatment, control, and prognosis: insights from the sub-cohort of China PEACE million persons project.","authors":"Weida Qiu, Anping Cai, Shiping Wu, Yanchen Zhu, He Zheng, Zhiqiang Nie, Jiabin Wang, Yingqing Feng","doi":"10.1038/s41440-024-02037-3","DOIUrl":"https://doi.org/10.1038/s41440-024-02037-3","url":null,"abstract":"It is unclear whether and to what extent hypertension (HTN) awareness, treatment, and control affect prognosis in real-world settings. This study utilized data from the sub-cohort of the China Patient-Centered Evaluative Assessment of Cardiac Events Million Persons Project. A total of 102,358 adults aged 35-75 years were enrolled from Guangdong Province between January 2016 and December 2020. The primary outcomes were hospitalizations for major adverse cardiovascular events (MACEs) (a composite of myocardial infarction, coronary heart disease, stroke, heart failure, and cardiovascular mortality) and all-cause mortality. The secondary outcomes were the individual components of MACEs. Among the HTN patients, the proportions of HTN awareness and treatment were 58.6% and 48.7%, respectively. Only 22.0% and 7.9% of the population had their blood pressure (BP) controlled at <140/90 and <130/80 mmHg. Older age, female sex, higher socioeconomic status, elevated body mass index and waist circumference, as well as a history of DM, dyslipidemia, and cardiovascular disease, were associated with increased HTN awareness, treatment, and control. Current smokers and drinkers experienced lower chances of HTN care cascade. Hypertensive individuals with BP controlled at <130/80 mmHg faced similar risks of MACEs and mortality compared to normotensive individuals, while hypertensive subjects with uncontrolled BP or unawareness of HTN exhibited nearly double the risk of adverse cardiovascular outcomes. In conclusion, several factors were significantly associated with the performance of HTN awareness, treatment, and control. Hypertensive individuals with BP controlled at an optimal level shared a similar risk for MACEs and mortality compared to their normotensive counterparts.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut microbiota modulation: a novel mechanism in arb-mediated hypertension treatment. 肠道菌群调节：青蒿素介导的高血压治疗的新机制。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02052-4

Dongdong Yang, Shengqi Fu, Yu Shi

引用次数: 0

Routine blood pressure measurement in Japan during student years. 日本学生时期的常规血压测量。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02048-0

Kei Asayama

引用次数: 0

A silent interplay between elevated intraocular pressure, glaucoma, and hypertension. 升高的眼压、青光眼和高血压之间无声的相互作用。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02038-2

Tatsuya Sato, Araya Umetsu, Marenao Tanaka, Hiroshi Ohguro, Masato Furuhashi

引用次数: 0

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02050-6

Minako Inoue, Satoko Sakata, Hisatomi Arima, Ikumi Yamato, Emi Oishi, Ai Ibaraki, Takanari Kitazono, Kenichi Goto

{"title":"Sleep-related breathing disorder in a Japanese occupational population and its association with exercise-induced blood pressure elevation.","authors":"Minako Inoue, Satoko Sakata, Hisatomi Arima, Ikumi Yamato, Emi Oishi, Ai Ibaraki, Takanari Kitazono, Kenichi Goto","doi":"10.1038/s41440-024-02050-6","DOIUrl":"https://doi.org/10.1038/s41440-024-02050-6","url":null,"abstract":"Sleep-related breathing disorder (SRBD) and exercise-induced blood pressure (BP) elevation are known risk factors for hypertension. However, the relation between them remains unknown. This cross-sectional study examined the relationship between SRBD and exercise-induced BP elevation in a Japanese occupational population. Using the 3% oxygen desaturation index (3%ODI) obtained by a portable monitor for overnight saturation of percutaneous oxygen (SpO2), participants were classified into low (0 ≤ 3%ODI < 5), medium (5 ≤ 3%ODI < 15), and high (15 ≤ 3%ODI) 3%ODI groups. We included employees who had undergone an exercise electrocardiogram test after monitoring for overnight SpO2. In total, 928 employees were included. The median age of the participants was 50 years, 96% were male, the mean body mass index was 23.9 ± 3.1 kg/m2, and the median 3%ODI was 4.9 (interquartile range: 1.6-6.5). Among them, 30% and 5% were categorized into the medium and high 3%ODI groups, respectively. At a median exercise intensity of 10.1 METs, BP changed from 124 ± 16/76 ± 12 mmHg before to 183 ± 26/85 ± 14 mmHg after exercise, with a mean systolic BP change of +59 ± 23 mmHg (-20 to +128 mmHg). When we defined systolic BP change of +60 mmHg or more as exercise-induced BP elevation, the odds ratio for exercise-induced BP elevation increased significantly with higher 3%ODI levels after multivariate adjustment for parameters including current use of antihypertensive medication and maximal exercise intensity (p for trend = 0.01). Higher 3%ODI was significantly associated with higher prevalence of exercise-induced BP elevation, suggesting sympathetic hyperactivity occurs in SRBD patients. Our results suggest the potential presence of SRBD should be considered in individuals with exercise-induced BP elevation.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The relationship between continuation of exercise habit for three years and endothelial function in patients with hypertension. 高血压患者持续三年运动习惯与内皮功能的关系。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02029-3

Takayuki Yamaji, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Takahiro Harada, Aya Mizobuchi, Tatsuya Maruhashi, Ayumu Nakashima, Hirofumi Tomiyama, Yukihito Higashi

{"title":"The relationship between continuation of exercise habit for three years and endothelial function in patients with hypertension.","authors":"Takayuki Yamaji, Farina Mohamad Yusoff, Shinji Kishimoto, Masato Kajikawa, Takahiro Harada, Aya Mizobuchi, Tatsuya Maruhashi, Ayumu Nakashima, Hirofumi Tomiyama, Yukihito Higashi","doi":"10.1038/s41440-024-02029-3","DOIUrl":"https://doi.org/10.1038/s41440-024-02029-3","url":null,"abstract":"The aim of this study was to evaluate the relationship between continuation of exercise habit for a long period and endothelial function assessed by flow-mediated vasodilation (FMD) in patients with hypertension. This study was a multicenter retrospective observational study. A total of 639 patients with hypertension were enrolled in this study. The subjects were divided into two groups based on information on exercise habit: a regular exercise group and a non-regular exercise group (control group). The regular exercise group was defined as patients who had an exercise habit during a 3-year follow-up period. There was no significant difference in FMD at baseline between the regular exercise group and control group. The change in FMD examined by the Wilcoxon signed rank test was significantly larger in the regular exercise group than in the control group (0.4 (-1.4, 2.0) % vs. -0.1 (-2.2, 1.4) %, p = 0.008). After adjustment for confounding factors for FMD, the odds ratio for increase in FMD was significantly larger in the regular exercise group than in the control groups. (OR: 1.59, 95% CI: 1.14-2.21, p = 0.006) A cubic spline curve revealed that even subjects with regular exercise who had a mean exercise intensity of less than 20 Mets・hour/week a had higher odds ratio for increase in endothelial function compared to the control group. These findings suggest that patients with hypertension who engage in regular exercise exhibited better endothelial function compared to those who do not exercise. Clinical Trial Registry Information: http://www.umin.ac.jp (UMIN000012951).","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fibrosis-4 index is closely associated with future development of hypertension in the Japanese general population. 在日本普通人群中，纤维化-4指数与高血压的未来发展密切相关。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02028-4

Sumiyo Yamashita, Hiroyuki Takase, Naomi Kawakatsu, Kazusa Hayashi, Fumihiko Kin, Takeru Isogaki, Yasuaki Dohi

{"title":"Fibrosis-4 index is closely associated with future development of hypertension in the Japanese general population.","authors":"Sumiyo Yamashita, Hiroyuki Takase, Naomi Kawakatsu, Kazusa Hayashi, Fumihiko Kin, Takeru Isogaki, Yasuaki Dohi","doi":"10.1038/s41440-024-02028-4","DOIUrl":"https://doi.org/10.1038/s41440-024-02028-4","url":null,"abstract":"The fibrosis-4 index, a noninvasive method for evaluating liver fibrosis, is closely associated with cardiovascular events. In this study, we tested the hypothesis that the fibrosis-4 index is associated with new-onset hypertension in the general population. A total of 15,502 individuals (51.0 ± 13.2 years) who participated in our health checkup program were screened. Participants with hypertension were excluded, and the remaining 8719 normotensive participants (48.4 ± 12.6 years) were followed up (median 1739 days) with the endpoint of the new onset of hypertension. During follow-up, 1750 participants (39.0 per 1000 person-years) developed hypertension. In Kaplan-Meier analysis, where participants were divided into three groups according to the fibrosis-4 index at baseline (low, <1.30; intermediate, 1.30-2.67; high, ≥2.67), the risk of hypertension increased with increasing fibrosis-4 index (low, 33.8; intermediate, 55.2; high, 69.4 per 1000 person-years). Multivariate Cox hazard regression analysis revealed that the log-transformed fibrosis-4 index was independently associated with the development of new hypertension (hazard ratio 4.279, 95% confidence interval 3.318-5.518). These results suggest that the fibrosis-4 index is a useful tool to evaluate a risk of developing hypertension in the general population. Hypertension and liver fibrosis may share a common basis.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The importance of the time in target range (TTR) of glucose and blood pressure. 血糖和血压在目标范围内时间（TTR）的重要性。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-12-05 DOI: 10.1038/s41440-024-02054-2

Tsuyoshi Okura

引用次数: 0