Hypertension Research最新文献_第9页

Utility of urinary sodium-to-potassium ratio for identifying individuals at elevated risk of heart failure 尿钠钾比在识别心力衰竭高危人群中的应用。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-08-01 DOI: 10.1038/s41440-025-02318-5

Keisuke Narita, Satoshi Hoshide, Kazuomi Kario

引用次数: 0

Isolated diastolic hypertension: methodological and clinical considerations 孤立性舒张期高血压：方法学和临床考虑。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-08-01 DOI: 10.1038/s41440-025-02322-9

Hiroki Ito, Takefumi Mori

引用次数: 0

New vasoconstriction factor in vascular smooth muscle cells 血管平滑肌细胞中的新血管收缩因子。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-08-01 DOI: 10.1038/s41440-025-02327-4

Masaki Mogi

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Wearable devices for physical activity: limited impact on blood pressure, unlimited potential for health innovation 用于身体活动的可穿戴设备：对血压影响有限，健康创新潜力无限。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-08-01 DOI: 10.1038/s41440-025-02321-w

Naoko Tomitani, Kazuomi Kario

引用次数: 0

Reply to Comment on: Effectiveness of digital health interventions for telemedicine/telehealth for managing blood pressure in adults: a systematic review and meta-analysis 答复关于以下问题的评论：远程医疗/远程保健管理成人血压的数字卫生干预措施的有效性：系统评价和荟萃分析。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-31 DOI: 10.1038/s41440-025-02325-6

Atsushi Sakima, Makiko Abe, Hisatomi Arima

引用次数: 0

Comment on: Effectiveness of digital health interventions for telemedicine/telehealth for managing blood pressure in adults: a systematic review and meta-analysis 评论：远程医疗/远程保健管理成人血压的数字卫生干预措施的有效性：系统评价和荟萃分析。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-31 DOI: 10.1038/s41440-025-02194-z

Xiaoxia Liu, Wenjuan Wang

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Report on the Joint Symposium of the Korean Society of CardioMetabolic Syndrome (KSCMS) and the Japanese Society of Hypertension (JSH) at the 8th Asia-Pacific CardioMetabolic Syndrome (APCMS) Congress in Seoul 韩国心脏代谢综合征学会（KSCMS）和日本高血压学会（JSH）在汉城举行的第8届亚太心脏代谢综合征（APCMS）大会上的联合研讨会报告。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-29 DOI: 10.1038/s41440-025-02310-z

Masanari Kuwabara, Keisuke Shinohara, Hack-Lyoung Kim, Mi-Hyang Jung, Eu Jeong Ku, Hyuk Sung Kwon, Seong Huan Choi, Seung Hwan Han, Kwang Kon Koh, Shin-ichiro Miura

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Sodium appetite is enhanced in 5/6 nephrectomized rat by high-sodium diet via increased levels of angiotensin II in the subfornical organ 在5/6肾切除大鼠中，高钠饮食通过增加皮质下器官血管紧张素II的水平来增强钠的食欲。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-29 DOI: 10.1038/s41440-025-02289-7

Taro Aoki, Naro Ohashi, Yuri Uchiyama, Takashi Matsuyama, Sayaka Ishigaki, Shinsuke Isobe, Masaru Ishibashi, Takamasa Iwakura, Tomoyuki Fujikura, Akihiko Kato, Ken Sugimoto, Hideo Yasuda

{"title":"Sodium appetite is enhanced in 5/6 nephrectomized rat by high-sodium diet via increased levels of angiotensin II in the subfornical organ","authors":"Taro Aoki, Naro Ohashi, Yuri Uchiyama, Takashi Matsuyama, Sayaka Ishigaki, Shinsuke Isobe, Masaru Ishibashi, Takamasa Iwakura, Tomoyuki Fujikura, Akihiko Kato, Ken Sugimoto, Hideo Yasuda","doi":"10.1038/s41440-025-02289-7","DOIUrl":"10.1038/s41440-025-02289-7","url":null,"abstract":"Intracerebral renin-angiotensin system (RAS) activation in the forebrain nuclei, such as the subfornical organ (SFO) is among the important factors that increase sodium appetite in rats. Although an increased sodium appetite in congestive heart failure and spontaneously hypertensive rats was reported previously, few reports have shown an increased sodium appetite in chronic kidney disease (CKD) model rats, for which salt restriction is important. Here, we aimed to verify whether CKD model rats show increased sodium appetite and if therapeutic intervention reducing sodium appetite by suppressing the intracerebral RAS is possible. In this study, 5/6 nephrectomized (5/6Nx) and control rats were fed a high-salt (4% NaCl) or low-salt (0.04% NaCl) diet. Angiotensin II (AngII) levels in kidney and the SFO, renal injury, and sodium appetite were evaluated after 2 weeks of salt loading. The 5/6Nx high-salt diet (Nx-HS) group was further divided into subgroups receiving continuous intracerebroventricular (ICV) administration of the angiotensin II type 1 receptor (AT1R) antagonist ZD 7155 or saline. Compared with the control rats, the 5/6Nx rats exhibited significantly increased levels of AngII in kidney and the SFO, accompanied by elevated blood pressure and worsened renal injury, especially in the Nx-HS group. In the Nx-HS group, an increased sodium appetite was observed that was attenuated by the ICV administration of ZD 7155 but not by saline. In conclusion, a high-salt diet enhanced the sodium appetite of 5/6Nx rats via increased levels of AngII in the SFO, which was attenuated by continuous ICV administration of an AT1R antagonist.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":"48 10","pages":"2595-2605"},"PeriodicalIF":4.6,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41440-025-02289-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of physical activity-promoting wearable devices on blood pressure in adults: a systematic review and meta-analysis 促进身体活动的可穿戴设备对成人血压的影响：系统回顾和荟萃分析。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-29 DOI: 10.1038/s41440-025-02260-6

Masayuki Koyama, Nobuaki Himuro, Kei Nakata, Keisuke Oyatani, Yukiko Shinohara, Hirofumi Ohnishi, Hisatomi Arima

{"title":"Effects of physical activity-promoting wearable devices on blood pressure in adults: a systematic review and meta-analysis","authors":"Masayuki Koyama, Nobuaki Himuro, Kei Nakata, Keisuke Oyatani, Yukiko Shinohara, Hirofumi Ohnishi, Hisatomi Arima","doi":"10.1038/s41440-025-02260-6","DOIUrl":"10.1038/s41440-025-02260-6","url":null,"abstract":"Hypertension affects more than 4 billion people worldwide and is a major risk factor for cardiovascular disease. Improving physical activity is an effective way to manage hypertension, and there has been a lot of interest in the use of wearable devices for promoting physical activity, which have become increasingly popular in recent years, but in many countries, improvements in physical activity levels remain inadequate. This systematic review and meta-analysis investigated whether interventions using wearable devices have a beneficial effect on blood pressure in adults. Following PRISMA 2020 guidelines and registered with PROSPERO (CRD42023442506), we searched PubMed, MEDLINE, Cochrane Library, and IchuShi-Web, identifying 21 randomized controlled trials including participants with hypertension, type 2 diabetes, or overweight/obesity. Interventions ranged from 12 to 48 weeks using pedometers, activity trackers, and smartwatches. Random-effects meta-analysis showed these interventions did not produce statistically significant improvements in systolic or diastolic blood pressure at any intervention duration (12, 24, or 48 weeks). Similarly, no statistically significant improvements were found in secondary outcomes (body weight, fasting blood glucose, and Hemoglobin A1c). Heterogeneity varied from low to high depending on outcome and intervention period. These findings indicate that evidence of direct intervention using wearable devices for promoting physical activity alone is currently insufficient to establish clinically meaningful improvements in blood pressure and related metabolic parameters. Future research may need to integrate wearable technology into comprehensive care models that combine targeted feedback and education with behavioral support strategies, rather than direct intervention through monitoring alone.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":"48 10","pages":"2677-2687"},"PeriodicalIF":4.6,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144742028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Redefining hyperuricemia in chronic kidney disease: a focus on tubulo-glomerular urate handling 重新定义慢性肾脏疾病中的高尿酸血症：关注小管-肾小球尿酸处理。

IF 4.6 2区医学

Hypertension Research Pub Date : 2025-07-29 DOI: 10.1038/s41440-025-02311-y

Tomoaki Takata, Yukari Mae, Shotaro Hoi, Ichiro Hisatome, Hajime Isomoto

引用次数: 0