Hypertension Research最新文献_第10页

Physicians' knowledge, awareness and instructions of home blood pressure monitoring: Asia HBPM survey in Taiwan. 医生对家庭血压监测的了解、认识和指导：台湾亚洲 HBPM 调查。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-08 DOI: 10.1038/s41440-024-01925-y

Yi-Syuan Lin, Hung-Ju Lin, Tzung-Dau Wang

{"title":"Physicians' knowledge, awareness and instructions of home blood pressure monitoring: Asia HBPM survey in Taiwan.","authors":"Yi-Syuan Lin, Hung-Ju Lin, Tzung-Dau Wang","doi":"10.1038/s41440-024-01925-y","DOIUrl":"https://doi.org/10.1038/s41440-024-01925-y","url":null,"abstract":"Home blood pressure monitoring (HBPM) has been proven to be reliable for both diagnosis and treatment of hypertension. Experts from 11 Asian countries collaborated to design a questionnaire aimed at healthcare workers, seeking to understand the current status of HBPM. A cross-sectional survey was conducted among healthcare professionals from Taiwan between November 2019 and June 2021. A total of 779 physicians in Taiwan participated in the survey. Nearly all physicians (97.7%) reported recommending HBPM to their patients. There was a 14.6% difference between the HBPM device ownership rate (60.2%) and the proportion of patients who measured their home blood pressures (45.6%). Among physicians who recommended HBPM, only 15.5% cited HBPM diagnostic threshold values consistent with the guidelines. Among all respondents, 85.9% and 48.9% viewed HBPM as highly recognized by physicians and patients, respectively. Lack of guidelines for HBPM and concern to reliability and accuracy of the HBPM devices were identified as key barriers to HBPM recognition. This study indicates that there is still room for improvement among healthcare providers in their understanding and implementation of HBPM in Taiwan.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Long-term results of the RADIANCE-HTN TRIO trial: strengths and limitations. 更正：RADIANCE-HTN TRIO 试验的长期结果：优势与局限。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-08 DOI: 10.1038/s41440-024-01947-6

Fosca Quarti Trevano, Cesare Cuspidi, Guido Grassi

引用次数: 0

Practical use and target value of urine sodium-to-potassium ratio in assessment of hypertension risk for Japanese: Consensus Statement by the Japanese Society of Hypertension Working Group on Urine Sodium-to-Potassium Ratio. 尿钠钾比值在评估日本人高血压风险中的实用性和目标值：日本高血压学会尿钠钾比值工作组共识声明》。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-08 DOI: 10.1038/s41440-024-01861-x

Takashi Hisamatsu, Mana Kogure, Yasuharu Tabara, Atsushi Hozawa, Atsushi Sakima, Takuya Tsuchihashi, Katsushi Yoshita, Hitomi Hayabuchi, Koichi Node, Yukari Takemi, Takayoshi Ohkubo, Katsuyuki Miura

{"title":"Practical use and target value of urine sodium-to-potassium ratio in assessment of hypertension risk for Japanese: Consensus Statement by the Japanese Society of Hypertension Working Group on Urine Sodium-to-Potassium Ratio.","authors":"Takashi Hisamatsu, Mana Kogure, Yasuharu Tabara, Atsushi Hozawa, Atsushi Sakima, Takuya Tsuchihashi, Katsushi Yoshita, Hitomi Hayabuchi, Koichi Node, Yukari Takemi, Takayoshi Ohkubo, Katsuyuki Miura","doi":"10.1038/s41440-024-01861-x","DOIUrl":"https://doi.org/10.1038/s41440-024-01861-x","url":null,"abstract":"Epidemiological studies have demonstrated that the urine sodium-to-potassium (Na/K) ratio is more positively associated with high blood pressure and cardiovascular disease risk than either urine sodium or potassium excretion alone. In this consensus statement, we recommend using the average Na/K ratio of casual urines randomly taken in various times on at least four days a week for a reliable individual estimate because of high day-to-day and intraday variability of casual urine Na/K ratio within individuals. Although a continuous positive association exists between the Na/K ratio and high blood pressure or cardiovascular disease risk, for clinical and public health decision making for Japanese, we recommend using an average urine Na/K ratio of 2 as an optimal target value because this aligns with recommendations for both sodium and potassium intake in the Dietary Reference Intakes for Japanese, 2020, considering a typical Japanese dietary pattern. We also suggest that an average urine Na/K ratio of 4 is a feasible target value to achieve a temporary goal of being below the mean values of the urine Na/K ratio across Japanese general populations. These recommendations apply mainly for apparently healthy individuals, but not for patients with specific conditions due to the lack of supporting data. Current evidence for the usefulness of measuring the urine Na/K ratio for the prevention or control of hypertension remains inconclusive and warrants further investigation.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142390162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Understanding preeclampsia from cutting edge knowledge-protecting maternal and fetal health. 从前沿知识了解子痫前期--保护孕产妇和胎儿健康。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-07 DOI: 10.1038/s41440-024-01932-z

Kanako Bokuda

引用次数: 0

The need for a personalized "implementation hypertension" strategy to facilitate the implementation of the new European Society of Hypertension (2023), European Society of Cardiology (2024) and the upcoming Japanese Society of Hypertension (2025) hypertension guidelines in clinical practice. 需要制定个性化的 "实施高血压 "战略，以促进在临床实践中实施新的欧洲高血压学会（2023 年）、欧洲心脏病学会（2024 年）和即将出台的日本高血压学会（2025 年）高血压指南。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-07 DOI: 10.1038/s41440-024-01927-w

Kazuomi Kario, Satoshi Hoshide, Masaki Mogi

引用次数: 0

Renal denervation up-to-date 2024: evidence and perspectives in Japan 直至 2024 年的肾脏去神经化：日本的证据和前景。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-07 DOI: 10.1038/s41440-024-01836-y

Kazuomi Kario, Satoshi Hoshide, Masaki Mogi

引用次数: 0

Suppressing the expression of steroidogenic acute regulatory protein (StAR) in the myocardium by spironolactone contributes to the improvement of right ventricular remodeling in pulmonary arterial hypertension. 螺内酯抑制类固醇生成急性调节蛋白（StAR）在心肌中的表达，有助于改善肺动脉高压患者的右心室重塑。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-04 DOI: 10.1038/s41440-024-01908-z

Hideki Imano, Tetsuya Hayashi, Atsuo Nomura, Saori Tanaka, Yuka Kohda, Takehiro Yamaguchi, Yasukatsu Izumi, Minoru Yoshiyama, Yoshinobu Hirose, Keiko Ohta-Ogo, Hatsue Ishibashi-Ueda, Ryuji Kato

{"title":"Suppressing the expression of steroidogenic acute regulatory protein (StAR) in the myocardium by spironolactone contributes to the improvement of right ventricular remodeling in pulmonary arterial hypertension.","authors":"Hideki Imano, Tetsuya Hayashi, Atsuo Nomura, Saori Tanaka, Yuka Kohda, Takehiro Yamaguchi, Yasukatsu Izumi, Minoru Yoshiyama, Yoshinobu Hirose, Keiko Ohta-Ogo, Hatsue Ishibashi-Ueda, Ryuji Kato","doi":"10.1038/s41440-024-01908-z","DOIUrl":"10.1038/s41440-024-01908-z","url":null,"abstract":"Pulmonary arterial hypertension (PAH) is a progressive condition that frequently leads to right ventricular (RV) remodeling. Aldosterone promotes vascular and RV remodeling. The upregulation of steroidogenic acute regulatory protein (StAR) stimulates aldosterone synthesis. However, the expression of StAR in the myocardium under PAH conditions remains unknown. To investigate the expression of StAR in the myocardium and its association with RV remodeling in PAH, utilizing spironolactone as a treatment. A PAH model was created using male Sprague-Dawley rats, which received a subcutaneous injection of Sugen5416 (20 mg/kg) and were exposed to hypoxia (10% O2) for 2 weeks, followed by 2 weeks of normoxia. The animals were then divided into two groups, with one group receiving spironolactone (25 mg/kg/day) for an additional 4 weeks, while the other group did not. H9c2 cells were cultured under hypoxic conditions (37 °C, 1% O2, 5% CO2) with or without spironolactone treatment. In the model rats, RV systolic pressure and the Fulton index, both of which increased upon exposure to Sugen5416 and hypoxia, significantly decreased with spironolactone treatment. In H9c2 cells, hypoxic exposure elevated aldosterone levels, while spironolactone treatment significantly suppressed aldosterone production. Suppression of StAR expression in the myocardium via spironolactone contributes to the improvement of RV remodeling in PAH. Spironolactone may offer a valuable therapeutic strategy for RV remodeling in patients with PAH.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating the complexities of obstructive sleep apnea: renalase rs2296545 as a key to managing hypertension. 驾驭阻塞性睡眠呼吸暂停的复杂性：肾酶 rs2296545 是控制高血压的关键。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-03 DOI: 10.1038/s41440-024-01931-0

Yusuke Koabayashi

引用次数: 0

Household fuel use and the regression from prehypertension to normotension among Chinese middle-aged and older adults: a cohort study. 家庭燃料使用与中国中老年人从高血压前期到正常血压的回归：一项队列研究。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-03 DOI: 10.1038/s41440-024-01928-9

Jia-Min Yan, Min-Zhe Zhang, Qi-Qiang He

{"title":"Household fuel use and the regression from prehypertension to normotension among Chinese middle-aged and older adults: a cohort study.","authors":"Jia-Min Yan, Min-Zhe Zhang, Qi-Qiang He","doi":"10.1038/s41440-024-01928-9","DOIUrl":"https://doi.org/10.1038/s41440-024-01928-9","url":null,"abstract":"To examine the association of household fuel use with prehypertension regression among middle-aged and older people based on the China Health and Retirement Longitudinal Study (CHARLS), we included a total of 3501 participants with prehypertension at baseline, and they were followed up from 2011-2012 to 2015-2016 with information on blood pressure and household solid fuel use (heating and cooking fuels). Cox proportional hazards regression models were used to explore the hazard ratio (HR) and 95% confidence interval (CI) between fuel use and prehypertension regression. Additionally, we investigated the impact of switching fuels (2011-2013) on the regression to normotension during the 4-year follow-up. Linear regression was used to examine the effect of household fuel use on changes in blood pressure. Compared to solid fuel users, those who used clean fuel for heating at baseline had a positive effect on the regression of prehypertension (HR: 1.28, 95% CI: 1.08-1.53). Participants who used clean fuels for both heating and cooking had increased odds for the regression of prehypertension (HR: 1.32, 95% CI: 1.09-1.60). Compared to consistent solid fuel users, those who consistently used clean fuel for heating had a higher likelihood of transitioning from prehypertension to normotension (HR: 1.36, 95% CI: 1.06-1.73) and exhibited 2.45 mmHg lower systolic blood pressure. In conclusion, household clean fuel use for heating was positively associated with the regression of prehypertension to normotension. Furthermore, switching from solid fuel to clean fuel for heating could reduce the risk of prehypertension in Chinese middle-aged and older adults.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic opportunities in targeting the protective arm of the renin-angiotensin system to improve insulin sensitivity: a mechanistic review. 针对肾素-血管紧张素系统的保护臂改善胰岛素敏感性的治疗机会：机理综述。

IF 4.3 2区医学

Hypertension Research Pub Date : 2024-10-03 DOI: 10.1038/s41440-024-01909-y

Fernando P Dominici, Mariela M Gironacci, Jorge A Narvaez Pardo

{"title":"Therapeutic opportunities in targeting the protective arm of the renin-angiotensin system to improve insulin sensitivity: a mechanistic review.","authors":"Fernando P Dominici, Mariela M Gironacci, Jorge A Narvaez Pardo","doi":"10.1038/s41440-024-01909-y","DOIUrl":"https://doi.org/10.1038/s41440-024-01909-y","url":null,"abstract":"In recent years, the knowledge of the physiological and pathophysiological roles of the renin-angiotensin system (RAS) in glucose metabolism has advanced significantly. It is now well-established that blockade of the angiotensin AT1 receptor (AT1R) improves insulin sensitivity. Activation of the AT2 receptor (AT2R) and the MAS receptor are significant contributors to this beneficial effect. Elevated availability of angiotensin (Ang) II) for interaction with the AT2R and increased Ang-(1-7) formation during AT1R blockade mediate these effects. The ongoing development of selective AT2R agonists, such as compound 21 and the novel Ang III peptidomimetics, has significantly advanced the exploration of the role of AT2R in metabolism and its potential as a therapeutic target. These agents show promise, particularly when RAS inhibition is contraindicated. Additionally, other RAS peptides, including Ang IV, des-Asp-Ang I, Ang-(1-9), and alamandine, hold therapeutic capability for addressing metabolic disturbances linked to type 2 diabetes. The possibility of AT2R heteromerization with either AT1R or MAS receptor offers an exciting area for future research, particularly concerning therapeutic strategies to improve glycemic control. This review focuses on therapeutic opportunities to improve insulin sensitivity, taking advantage of the protective arm of the RAS.","PeriodicalId":13029,"journal":{"name":"Hypertension Research","volume":" ","pages":""},"PeriodicalIF":4.3,"publicationDate":"2024-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0