Hormones and Behavior最新文献

{"title":"Role of interdependent self-construal in predicting acute salivary cortisol response, hair cortisol concentrations, and their associations","authors":"Jiahao Luo ,&nbsp;Zhenni Wei ,&nbsp;Yadong Liu ,&nbsp;Kaige Guo ,&nbsp;Xiaolin Zhao ,&nbsp;Yipeng Ren ,&nbsp;Yan Wu ,&nbsp;Juan Yang","doi":"10.1016/j.yhbeh.2024.105650","DOIUrl":"10.1016/j.yhbeh.2024.105650","url":null,"abstract":"<div><div>Numerous studies have associated interdependent self-construal (InterSC) with heightened acute salivary cortisol stress responses in collectivist cultures. Hair cortisol concentration (HCC) is an important biomarker of chronic stress and is associated with acute salivary cortisol stress response. However, few studies have explored the association between InterSC and HCC. This study aimed to investigate the role of InterSC in the acute salivary cortisol stress response, HCC, and their associations. Seventy-seven healthy Chinese participants underwent assessments of InterSC, social anxiety, and HCC. The ScanSTRESS paradigm was used to induce an acute stress response and saliva samples were collected. These results replicated earlier findings showing that InterSC was associated with rapid salivary cortisol reactivity and recovery during acute stress. Additionally, InterSC was positively correlated with HCC, and social anxiety mediated this association. Importantly, InterSC moderated the HCC–acute salivary cortisol stress response association. Specifically, high HCC predicted a blunted acute salivary cortisol stress response in participants with low InterSC, including a slow salivary cortisol response during the acute stress reactivity phase and a small overall acute salivary cortisol response. However, this blunting effect was not observed with high InterSC participants, indicating that high InterSC buffered the blunting effect of HCC on the acute salivary cortisol stress response. In conclusion, this study provided new insights into how InterSC is associated with the hypothalamus-pituitary-adrenal axis stress system and revealed the dual-faceted role of InterSC for acute salivary cortisol stress and HCC.</div></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105650"},"PeriodicalIF":2.5,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal obesity induces sex-specific changes in the endocannabinoid system of the hypothalamus and dorsal hippocampus of offspring associated with anxiety-like behavior in adolescent female rats","authors":"Camila Calvino ,&nbsp;Mariana Macedo de Almeida ,&nbsp;Clara Figueredo Reis-Gomes ,&nbsp;Brenda da Silva Andrade ,&nbsp;Gilda Angela Neves ,&nbsp;Carmen Cabanelas Pazos-Moura ,&nbsp;Isis Hara Trevenzoli","doi":"10.1016/j.yhbeh.2024.105648","DOIUrl":"10.1016/j.yhbeh.2024.105648","url":null,"abstract":"<div><div>Maternal obesity during perinatal period increases the risk of metabolic and behavioral deleterious outcomes in the offspring, since it is critical for brain development, maturation, and reorganization. These processes are highly modulated by the endocannabinoid system (ECS), which comprises the main lipid ligands anandamide and 2-arachidonoylglycerol, cannabinoid receptors 1 and 2 (CB1R and CB2R), and several metabolizing enzymes. The ECS is overactivated in obesity and it contributes to the physiological activity of the hypothalamus-pituitary-adrenal (HPA) axis, promoting stress relief. We have previously demonstrated that maternal high-fat diet during gestation and lactation programmed the food preference for fat in adolescent male offspring and adult male and female offspring. In the present study, we hypothesized that maternal diet-induced obesity would induce sex-specific changes of the ECS in the hypothalamus and dorsal hippocampus of rat offspring associated with dysregulation of the HPA axis and stress-related behavior in adolescence. Rat dams were fed a control (C) or an obesogenic high-fat high-sugar diet (OD) for nine weeks prior to mating and throughout gestation and lactation. Maternal obesity differentially altered the CB1R in the hypothalamus of neonate offspring, with significant increase in male but not in female pups, associated with decreased CB2R prior to obesity development. In adolescence, maternal obesity induced anxiety-like behavior only in adolescent females which was associated with increased content of CB1R in the dorsal hippocampus. Our findings suggest that the early origins of anxiety disorders induced by maternal exposome is associated with dysregulation of the brain ECS, with females being more susceptible.</div></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105648"},"PeriodicalIF":2.5,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aging leads to sex-dependent effects on pair bonding and increased number of oxytocin-producing neurons in monogamous prairie voles","authors":"Michael A. Kelberman ,&nbsp;Kelly E. Winther ,&nbsp;Yana M. Medvedeva ,&nbsp;Zoe R. Donaldson","doi":"10.1016/j.yhbeh.2024.105647","DOIUrl":"10.1016/j.yhbeh.2024.105647","url":null,"abstract":"<div><div>Pair bonds powerfully modulate health, which becomes particularly important when facing the detrimental effects of aging. To examine the impact of aging on relationship formation and response to loss, we examined behavior in naive 6-, 12-, and 18-month male and female prairie voles, a monogamous species that forms mating-based pair bonds. We found that older males (18-months) bonded quicker than younger voles, while similarly aged female voles increased partner directed affiliative behaviors. Supporting sex differences in bonding behaviors, we found that males were more likely to sample both partner and stranger voles while females were more likely to display partner preference during the initial 20 min of the test. We also found that male voles of all ages show enduring bonding behavior despite four weeks of partner separation while females show an overall decrease in partner-directed affiliation, including an erosion of partner preference in 12-month females. Finally, we found that the number of oxytocin, but not vasopressin, cells in the paraventricular hypothalamus increased at 18 months of age. These results establish prairie voles as a novel model to study the effects of normal and abnormal aging on pair bonding.</div></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105647"},"PeriodicalIF":2.5,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A supergene affects androgen concentrations during early development in a bird with alternative reproductive morphs","authors":"Lina M. Giraldo-Deck ,&nbsp;Jasmine L. Loveland ,&nbsp;Wolfgang Goymann ,&nbsp;David B. Lank ,&nbsp;Clemens Küpper","doi":"10.1016/j.yhbeh.2024.105645","DOIUrl":"10.1016/j.yhbeh.2024.105645","url":null,"abstract":"<div><div>Species with alternative reproductive tactics typically show pronounced phenotypic variation between and within sexes. In some species, this variation culminates in discrete reproductive morphs that are genetically determined, facilitating studies on how genetic variation translates into phenotypic variation. In ruffs (<em>Calidris pugnax</em>), an autosomal inversion polymorphism underlies three reproductive morphs (Independents, Satellites and Faeders), which differ in circulating steroid concentrations in adults. Yet, it remains unknown whether morph differences in steroid concentrations already arise before adulthood. We examined variation in circulating testosterone, androstenedione and progesterone concentrations between morphs and sexes in ruff chicks and juveniles and compared the differences to those in adults. Since measured hormone concentrations only provide momentary states and show high within- and between-individual variation, we took repeated measurements to compare means, variances and skewness between groups. We found clear differences between morphs but not the sexes in early life. Between morphs, androgen concentrations in young ruffs differed in variance and skewness, but not in their means. For testosterone, Independents had a higher variance than Satellites/Faeders, whereas for androstenedione, we observed the opposite pattern. For progesterone, we did not detect clear differences between groups. Skewness values mirrored differences in morph variances. Compared to adults, premature ruffs had lower androgen concentrations. In both life stages, we detected morph-specific associations between androgen concentrations: androstenedione concentrations increased with testosterone concentrations more in Satellites/Faeders than in Independents. These observed morph differences during early life are consistent with a supergene-mediated regulation of androgen variation that underlies the diversification of adult behavioural phenotypes.</div></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105645"},"PeriodicalIF":2.5,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"","authors":"Randy J. Nelson","doi":"10.1016/j.yhbeh.2024.105649","DOIUrl":"10.1016/j.yhbeh.2024.105649","url":null,"abstract":"","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105649"},"PeriodicalIF":2.5,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142357946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensory cues of predation risk generate sex-specific changes in neural activity and behavior, but not hormones, in Trinidadian guppies","authors":"A.E. Merritt ,&nbsp;M.E. St. John,&nbsp;F. Leri,&nbsp;L.R. Stein","doi":"10.1016/j.yhbeh.2024.105635","DOIUrl":"10.1016/j.yhbeh.2024.105635","url":null,"abstract":"<div><p>How an organism responds to risk depends on how that individual perceives such risk. Integrating cues from multiple sensory modalities allows individuals to extract information from their environment, and whether and how the brain and body respond differently to different sensory cues can help reveal mechanistic decision-making processes. Here, we assessed neural, hormonal, and behavioral responses to different sensory cues of predation risk in Trinidadian guppies (<em>Poecilia reticulata</em>). Adult guppies were assigned to one of four treatment groups: control, visual, olfactory, and both sensory cues combined from a natural predator, the pike cichlid (<em>Crenicichla alta</em>), for 2 h. We found no difference in glucocorticoid response to any cue. However, we found behavioral and neural activation responses to olfactory-only cues. In addition, we found a sex by treatment effect, where males showed greater changes in neural activation in brain regions associated with avoidance behavior, while females showed greater changes in neural activation in regions associated with social behavior and memory, mirroring sex by treatment differences in behavioral antipredator responses. Altogether, our results demonstrate that single and combinatory cues may influence risk-taking behavior differently based on sex, suggesting that perception and integration of cues can cascade into sex differences in behavior.</p></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105635"},"PeriodicalIF":2.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0018506X24001600/pdfft?md5=0d7012b8ee9ade8c7a4cbce6b5a0c1f4&pid=1-s2.0-S0018506X24001600-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The modulation of social and non-social behavior by arginine vasotocin in the common waxbill, Estrilda astrild","authors":"Pedro Oliveira ,&nbsp;Marta C. Soares ,&nbsp;Sandra Trigo","doi":"10.1016/j.yhbeh.2024.105646","DOIUrl":"10.1016/j.yhbeh.2024.105646","url":null,"abstract":"<div><p>The influence of the neuropeptide arginine vasotocin (AVT) has been demonstrated across various species, on an ample range of behaviors, yet the results appear to be highly species-specific. In this study, we aimed to test how AVT influences both social and non-social behaviors in the common waxbill <em>Estrilda astrild</em>, a highly social estrildid finch. Through a within-subject design study, we experimentally manipulated AVT pathways through muscular injections of both an agonist and an antagonist of AVT at different dosages, and performed competition over food tests to assess behavioral changes. Our observations reveal a decrease in birds' movements with both low and high dosages of AVT. Additionally, the higher AVT dosage led to a significant decrease in birds' feeding, aggressive behavior, and allopreening. Conversely, the lower AVT dosage increased the duration of allopreening, which is a proxy for affiliation. The use of Manning Compound, a V1a antagonist, did not produce any changes in behavior, however, the absence of affinity studies for this compound in birds makes it difficult to interpret these results. It is plausible that in common waxbills, AVT V1b or V1a receptors may be involved in regulating movement, feeding, aggressive behavior, and allopreening, rather than V2 AVT receptors.</p></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105646"},"PeriodicalIF":2.5,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0018506X24001715/pdfft?md5=ccf86b81307cd58d6a4b4ee1b30614bd&pid=1-s2.0-S0018506X24001715-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142241966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex is a biologically coherent concept: A response to Massa et al., 2023","authors":"Davide Ponzi,&nbsp;Paola Palanza","doi":"10.1016/j.yhbeh.2024.105636","DOIUrl":"10.1016/j.yhbeh.2024.105636","url":null,"abstract":"","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105636"},"PeriodicalIF":2.5,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142232649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mood symptoms and gut function across the menstrual cycle in individuals with premenstrual syndrome","authors":"Kelsey Hannan ,&nbsp;Ximin Li ,&nbsp;Anjali Mehta ,&nbsp;Gayane Yenokyan ,&nbsp;Jennifer L. Payne ,&nbsp;Amanda A. Shea ,&nbsp;Liisa Hantsoo","doi":"10.1016/j.yhbeh.2024.105634","DOIUrl":"10.1016/j.yhbeh.2024.105634","url":null,"abstract":"<div><p>Gastrointestinal (GI) symptoms such as bloating, constipation, and nausea are common in the days before menstruation, experienced by as many as 73 % of menstruating individuals. Mood may influence the link between menstrual cycle and GI symptoms, with prior studies indicating that even among healthy controls, GI symptoms worsen premenstrually and are associated with worsening mood. Associations between GI symptoms and mood are poorly understood among those with premenstrual syndrome (PMS), a cluster of mood and/or physical symptoms that occur in the week before menses affecting roughly 20 % of menstruators. Our primary aim was to examine associations between GI symptoms and mood symptoms across the menstrual cycle, in those who do and do not report PMS using a menstrual tracking app. We hypothesized that GI symptoms would be reported more frequently in the luteal phase than follicular phase, and that frequency of GI symptoms would be positively associated with mood symptoms in those with PMS. We analyzed data from 33,628 menstrual cycles across 32,241 participants, including <em>n</em> = 27,897 controls (29,137 menstrual cycles) and <em>n</em> = 4344 PMS participants (4491 menstrual cycles). GI symptoms were reported significantly more frequently in the luteal phase than the follicular phase in both control and PMS groups (<em>p</em> &lt; 0.001). Mood symptoms were significantly positively associated with GI symptoms in both groups, in both follicular and luteal phases (<em>p</em> &lt; 0.001). Results suggest that premenstrual GI symptoms are a common issue, and additional work is needed to explore associations between mood and GI symptoms in the context of the menstrual cycle.</p></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"166 ","pages":"Article 105634"},"PeriodicalIF":2.5,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142168288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of time of day on memory recognition for faces","authors":"Lisa Pötzl,&nbsp;Oliver T. Wolf,&nbsp;Christian J. Merz","doi":"10.1016/j.yhbeh.2024.105633","DOIUrl":"10.1016/j.yhbeh.2024.105633","url":null,"abstract":"<div><p>Time of day can alter memory performance in general. Its influence on memory recognition performance for faces, which is important for daily encounters with new persons or testimonies, has not been investigated yet. Importantly, high levels of the stress hormone cortisol impair memory recognition, in particular for emotional material. However, some studies also reported high cortisol levels to enhance memory recognition. Since cortisol levels in the morning are usually higher than in the evening, time of day might also influence recognition performance. In this pre-registered study with a two-day design, 51 healthy men encoded pictures of male and female faces with distinct emotional expressions on day one around noon. Memory for the faces was retrieved two days later at two consecutive testing times either in the morning (high and moderately increased endogenous cortisol levels) or in the evening (low endogenous cortisol levels). Additionally, alertness as well as salivary cortisol levels at the different timepoints was assessed. Cortisol levels were significantly higher in the morning compared to the evening group as expected, while both groups did not differ in alertness. Familiarity ratings for female stimuli were significantly better when participants were tested during moderately increased endogenous cortisol levels in the morning than during low endogenous cortisol levels in the evening, a pattern which was previously also observed for stressed versus non-stressed participants. In addition, cortisol levels during that time in the morning were positively correlated with the recollection of face stimuli in general. Thus, recognition memory performance may depend on the time of day and as well as on stimulus type, such as the difference of male and female faces. Most importantly, the results suggest that cortisol may be meaningful and worth investigating when studying the effects of time of day on memory performance. This research offers both, insights into daily encounters as well as legally relevant domains as for instance testimonies.</p></div>","PeriodicalId":13001,"journal":{"name":"Hormones and Behavior","volume":"165 ","pages":"Article 105633"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0018506X24001582/pdfft?md5=63b5ed7faf663338bd1cd89490c3cd0e&pid=1-s2.0-S0018506X24001582-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142147840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}