Heart, Lung and Circulation最新文献

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Erratum to: Abstract 313, “Is Acute Clozapine-Induced Hypersensitivity Myocarditis Over-Diagnosed in Australia?” [Heart, Lung and Circulation, Volume 33, Supplement 4, August 2024, Page S158, (Abstracts for the 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, 1–4 August 2024, Perth, Australia)].
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.11.008
H. Slifirski , S. Toukhsati , D. Hare , K. Huang
{"title":"Erratum to: Abstract 313, “Is Acute Clozapine-Induced Hypersensitivity Myocarditis Over-Diagnosed in Australia?” [Heart, Lung and Circulation, Volume 33, Supplement 4, August 2024, Page S158, (Abstracts for the 72nd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, 1–4 August 2024, Perth, Australia)].","authors":"H. Slifirski , S. Toukhsati , D. Hare , K. Huang","doi":"10.1016/j.hlc.2024.11.008","DOIUrl":"10.1016/j.hlc.2024.11.008","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Page e80"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143158017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Knowledge of Acute Coronary Syndrome Symptoms and the Intention to Call Emergency Medical Services in Culturally and Linguistically Diverse Australians 具有不同文化和语言背景的澳大利亚人对急性冠状动脉综合征症状的了解以及拨打紧急医疗服务电话的意愿。
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.07.008
Ararso Baru Olani MSc, MHS , Kathryn Eastwood PhD , Stuart Howell PhD , Amanda Buttery PhD , Janet E. Bray PhD
{"title":"Knowledge of Acute Coronary Syndrome Symptoms and the Intention to Call Emergency Medical Services in Culturally and Linguistically Diverse Australians","authors":"Ararso Baru Olani MSc, MHS ,&nbsp;Kathryn Eastwood PhD ,&nbsp;Stuart Howell PhD ,&nbsp;Amanda Buttery PhD ,&nbsp;Janet E. Bray PhD","doi":"10.1016/j.hlc.2024.07.008","DOIUrl":"10.1016/j.hlc.2024.07.008","url":null,"abstract":"<div><h3>Background</h3><div>Prompt recognition of symptoms and response to acute coronary syndrome (ACS) are crucial for reducing pre-hospital delay. This study compares culturally and linguistically diverse (CALD) and non-CALD Australian populations in terms of their (i) ACS symptom knowledge and (ii) intention to call emergency medical services (EMS) for ACS.</div></div><div><h3>Method</h3><div>This cross-sectional study used data from HeartWatch, an online survey collected by the National Heart Foundation of Australia between 2018 and 2020 for Australian adults aged ≥18 years. CALD respondents were defined as non-Indigenous individuals who reported speaking a language other than English at home. Characteristics associated with ACS symptom knowledge and EMS calling intentions were analysed using multivariable logistic regression.</div></div><div><h3>Results</h3><div>Of 31,919 respondents, 16.3% were from CALD backgrounds (n=5,212). Compared with non-CALD, CALD respondents were less likely to name any ACS symptom (63.0% vs 76.0%; adjusted odds ratio [AOR] 0.66; 95% confidence interval [CI] 0.61–0.70) and were less likely to state that they would call an ambulance for ACS (50.2% vs 72.1%; AOR 0.53; 95% CI 0.50–0.57). Almost one-quarter (23.0%) of CALD respondents reported not knowing what they would do. In both groups, males, individuals aged ≤60 years, and those with diabetes were less likely to name an ACS symptom and had lower intention to call an ambulance. Those unable to list a single ACS symptom also had a lower intention to call an ambulance.</div></div><div><h3>Conclusions</h3><div>Knowledge of ACS symptoms and intention to call an ambulance were lower among CALD respondents. The demographics of those with low ACS symptom knowledge and EMS calling intention were similar in the two groups. Future education efforts in Australia should focus on promoting ACS symptom knowledge and EMS use and should target these groups.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1659-1669"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in Sudden Unexpected Deaths in an Australian Population: Impact of the COVID-19 Pandemic 澳大利亚人口的意外猝死趋势:COVID-19 大流行的影响。
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.07.009
James Healy MD , Andrew M. Youssef MD, PhD , Sonia Sawant MD , Jessica J. Orchard MPH, PhD , Rajan Rehan MD , Rianie Van Vuuren MD , John W. Orchard MBBS, PhD , Christopher Semsarian MBBS, PhD , Rajesh Puranik MBBS, PhD
{"title":"Trends in Sudden Unexpected Deaths in an Australian Population: Impact of the COVID-19 Pandemic","authors":"James Healy MD ,&nbsp;Andrew M. Youssef MD, PhD ,&nbsp;Sonia Sawant MD ,&nbsp;Jessica J. Orchard MPH, PhD ,&nbsp;Rajan Rehan MD ,&nbsp;Rianie Van Vuuren MD ,&nbsp;John W. Orchard MBBS, PhD ,&nbsp;Christopher Semsarian MBBS, PhD ,&nbsp;Rajesh Puranik MBBS, PhD","doi":"10.1016/j.hlc.2024.07.009","DOIUrl":"10.1016/j.hlc.2024.07.009","url":null,"abstract":"<div><h3>Background &amp; Aim</h3><div>SARS-CoV-2 infection is associated with increased cardiovascular (CV) morbidity and mortality, manifesting as increased adverse outcomes in the first 30 days, extending to 12 months. This study aimed to investigate trends in sudden unexpected deaths between 2018 and 2022, with a focus on CV deaths.</div></div><div><h3>Method</h3><div>A retrospective analysis was performed on autopsy reports (n=9,330) obtained from New South Wales Coroners Court, Australia, specifically targeting cases of unexplained deaths that occurred between 2018 and 2022. Statistical analysis was conducted using chi-square tests and a <em>post hoc</em> analysis with Bonferroni correction, as well as analysis of variance with multiple comparisons.</div></div><div><h3>Results</h3><div>There were 349 (18.3%) CV deaths in 2018, 346 (18.0%) in 2019, 338 (17.5%) in 2020, 395 (21.9%) in 2021, and (23.4%) 413 in 2022 (p=0.0002). Among CV deaths, the number of deaths from sudden arrhythmic death syndrome were 25 (7.2%) in 2018, 26 (7.5%) in 2019, 18 (5.3%) in 2020, 52 (13.2%) in 2021, and 80 (19.4%) in 2022 (p=0.0001). Atherosclerosis was the most common cause of death among all CV categories; there were 196 (56.2%) atherosclerosis deaths in 2018, 207 (59.8%) in 2019, 192 (56.8%) in 2020, 221 (56.0%) in 2021, and 197 (47.7%) in 2022 (p=0.43). The average age of death from sudden arrhythmic death syndrome (42.8±19.1 years) across 2018–2022 was younger than atherosclerosis (56.2±12.4 years) and total groups (53.1±15.1 years) (p&lt;0.001). Males comprised 76% of all CV deaths from 2018 to 2022 (p&lt;0.0001).</div></div><div><h3>Conclusions</h3><div>Compared with pre-pandemic data, a noteworthy increase in CV deaths was observed in occurrence with the escalation in COVID-19 cases in Australia. This may be attributed to direct or indirect factors, such as lifestyle modifications, disrupted access to routine cardiac care, or COVID-19 infection–triggered CV deaths.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1693-1698"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodality Imaging Evaluation of Tumour Peeking Its Head Into the Right Atrium 肿瘤头部探入右心房的多模态成像评估
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.06.1039
Kouta Nakamura MT , Akinobu Miyazaki MT , Masahiro Suzuki MD , Ken-ichi Imasaka MD, PhD , Kisho Ohtani MD, PhD
{"title":"Multimodality Imaging Evaluation of Tumour Peeking Its Head Into the Right Atrium","authors":"Kouta Nakamura MT ,&nbsp;Akinobu Miyazaki MT ,&nbsp;Masahiro Suzuki MD ,&nbsp;Ken-ichi Imasaka MD, PhD ,&nbsp;Kisho Ohtani MD, PhD","doi":"10.1016/j.hlc.2024.06.1039","DOIUrl":"10.1016/j.hlc.2024.06.1039","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages e67-e68"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reply to Letter to the Editor “Addressing Gaps in Post-MI Medication Use Study” regarding: “Patterns of 12-Month Post-Myocardial Infarction Medication Use According to Revascularisation Strategy: Analysis of 15,339 Admissions in Victoria, Australia” 回复致编辑的信 "弥补心肌梗死后用药研究的不足",内容涉及"心肌梗塞后 12 个月用药模式取决于血管重建策略:对澳大利亚维多利亚州 15,339 例入院患者的分析"。
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.10.007
Adam C. Livori MClinPharm , Zanfina Ademi MPH, PhD , Jenni Ilomäki PhD , Adam J. Nelson MBBS, MPH, MBA, PhD , J. Simon Bell PhD , Jedidiah I. Morton PhD
{"title":"Reply to Letter to the Editor “Addressing Gaps in Post-MI Medication Use Study” regarding: “Patterns of 12-Month Post-Myocardial Infarction Medication Use According to Revascularisation Strategy: Analysis of 15,339 Admissions in Victoria, Australia”","authors":"Adam C. Livori MClinPharm ,&nbsp;Zanfina Ademi MPH, PhD ,&nbsp;Jenni Ilomäki PhD ,&nbsp;Adam J. Nelson MBBS, MPH, MBA, PhD ,&nbsp;J. Simon Bell PhD ,&nbsp;Jedidiah I. Morton PhD","doi":"10.1016/j.hlc.2024.10.007","DOIUrl":"10.1016/j.hlc.2024.10.007","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages e77-e78"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Fibrillation is an Important String to our Surgical Bow: Lets do More! 心房颤动是我们外科弓的重要一环:让我们做得更多!
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.11.004
Jaishankar Raman MMed, PhD, FRACS , John Alvarez FRACS
{"title":"Atrial Fibrillation is an Important String to our Surgical Bow: Lets do More!","authors":"Jaishankar Raman MMed, PhD, FRACS ,&nbsp;John Alvarez FRACS","doi":"10.1016/j.hlc.2024.11.004","DOIUrl":"10.1016/j.hlc.2024.11.004","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1609-1610"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Perforation of the Septal Perforators: A Case Series and Proposed Management Paradigm 房间隔穿孔:一个病例系列和拟议的治疗范例。
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.09.006
Daniel G. Brieger FRACP , Aditya Bhat DrPH, FRACP , Ravinay Bhindi PhD, FRACP, FCSANZ , Michael R. Ward PhD, FRACP, FCSANZ
{"title":"Perforation of the Septal Perforators: A Case Series and Proposed Management Paradigm","authors":"Daniel G. Brieger FRACP ,&nbsp;Aditya Bhat DrPH, FRACP ,&nbsp;Ravinay Bhindi PhD, FRACP, FCSANZ ,&nbsp;Michael R. Ward PhD, FRACP, FCSANZ","doi":"10.1016/j.hlc.2024.09.006","DOIUrl":"10.1016/j.hlc.2024.09.006","url":null,"abstract":"<div><div>Septal artery perforations are an uncommon complication of percutaneous coronary intervention. Unlike epicardial vessels, septal perforations do not result in pericardial effusions but rather produce septal haematomas. While most can be managed expectantly, a small proportion requires active management to prevent rapid haematoma expansion resulting in compromise of right ventricular filling and ‘dry tamponade’. We present two cases of septal artery perforation during percutaneous coronary intervention and propose a management approach that takes into account the unique haemodynamic consequences of this complication.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1616-1620"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142499358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Atrial Fibrillation Surgery in Australia: Are We Doing Enough? 澳大利亚的心房颤动手术:我们做得够不够?
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.07.007
Frazer Kirk MBBS, MSurg , Matthew S. Yong PhD, FRACS , Lavinia Tran BMedSc, PhD , Andrew Newcomb FRACS , Cheng He BMedSc, FRACS , Andrie Stroebel MBChB, MMed, FRACS
{"title":"Atrial Fibrillation Surgery in Australia: Are We Doing Enough?","authors":"Frazer Kirk MBBS, MSurg ,&nbsp;Matthew S. Yong PhD, FRACS ,&nbsp;Lavinia Tran BMedSc, PhD ,&nbsp;Andrew Newcomb FRACS ,&nbsp;Cheng He BMedSc, FRACS ,&nbsp;Andrie Stroebel MBChB, MMed, FRACS","doi":"10.1016/j.hlc.2024.07.007","DOIUrl":"10.1016/j.hlc.2024.07.007","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to examine contemporary burden and treatment trends of atrial fibrillation (AF) in patients undergoing cardiac surgery in Australia and New Zealand. This allows comparison of contemporary practice with the Society of Thoracic Surgeons guideline recommendations for the surgical treatment of AF in patients undergoing cardiac surgery.</div></div><div><h3>Method</h3><div>A 10-year retrospective review of the Australian &amp; New Zealand Society of Cardiac &amp; Thoracic Surgeons National Cardiac Surgery Database was performed, examining all adult cardiac surgery patients from 2011 to 2021. Patients were grouped by the presence or absence of AF, and simple descriptive statistical analysis was performed to assess baseline demographics and premorbid condition of the patients. The incidence of AF was analysed by type of surgery. Trends for surgical treatment of AF were then analysed using simple descriptive statistics, examining isolated left atrial appendage ligation, isolated surgical ablation, and combined ligation and ablation.</div></div><div><h3>Results</h3><div>In the last 10 years, the Australian &amp; New Zealand Society of Cardiac &amp; Thoracic Surgeons database has recorded 140,680 patients who underwent cardiac surgery. Atrial fibrillation (AF) was present in 21,077 patients (14%). Patients with AF were generally older (72.25 vs 66.65 years; p&lt;0.001). Among patients undergoing cardiac surgery, AF was more common in female than in male patients (18% vs 13%, respectively). Patients with AF more often had a higher classification of dyspnoea according to the New York Heart Association and lower ejection fractions compared with their AF-free counterparts. The incidence of AF as a comorbid condition was more frequent in patients undergoing mitral valve surgery or combined coronary artery bypass grafting and valve surgery (aortic, mitral, or both) compared with those undergoing isolated coronary or aortic surgery. Only 11.90% (n=2,509) of patients with AF received a combined ablation and left atrial appendage ligation, and 19.54% (n=693) of those received a Cox-Maze IV ablation.</div></div><div><h3>Conclusions</h3><div>The burden of concomitant AF in patients undergoing cardiac surgery in Australia is higher than previously reported (14% vs 5%–11%). Despite strong recommendation for the surgical management of AF in patients undergoing cardiac surgery and clear evidence of its benefit, both left atrial appendage ligation and surgical ablation independently or concomitantly remain heavily underutilised in this cohort.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1627-1637"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142375323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction notice: Adherence to Cardiac Medications in Patients With Atrial Fibrillation: A Pilot Study 撤回通知:心房颤动患者心脏药物依从性:一项试点研究:[心脏,肺和循环,第29卷,第7期,2020年7月,页e131-e139]。
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.11.009
Adrienne Pacleb BN , Nicole Lowres PhD , Sue Randall PhD , Lis Neubeck PhD , Robyn Gallagher PhD
{"title":"Retraction notice: Adherence to Cardiac Medications in Patients With Atrial Fibrillation: A Pilot Study","authors":"Adrienne Pacleb BN ,&nbsp;Nicole Lowres PhD ,&nbsp;Sue Randall PhD ,&nbsp;Lis Neubeck PhD ,&nbsp;Robyn Gallagher PhD","doi":"10.1016/j.hlc.2024.11.009","DOIUrl":"10.1016/j.hlc.2024.11.009","url":null,"abstract":"","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Page R3"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sex-Related Differences in Outcome of Patients Treated With Microaxial Percutaneous Left Ventricular Assist Device for Cardiogenic Shock 使用微轴经皮左心室辅助装置治疗心源性休克的患者预后中与性别有关的差异
IF 2.2 4区 医学
Heart, Lung and Circulation Pub Date : 2024-12-01 DOI: 10.1016/j.hlc.2024.07.010
Johannes Mierke MD, Thomas Nowack MD, Frederike Poege MD, Marie Celine Schuster MD, Krunoslav Michael Sveric MD, Stefanie Jellinghaus MD, Felix J. Woitek MD, Stephan Haussig MD, Axel Linke MD, Norman Mangner MD
{"title":"Sex-Related Differences in Outcome of Patients Treated With Microaxial Percutaneous Left Ventricular Assist Device for Cardiogenic Shock","authors":"Johannes Mierke MD,&nbsp;Thomas Nowack MD,&nbsp;Frederike Poege MD,&nbsp;Marie Celine Schuster MD,&nbsp;Krunoslav Michael Sveric MD,&nbsp;Stefanie Jellinghaus MD,&nbsp;Felix J. Woitek MD,&nbsp;Stephan Haussig MD,&nbsp;Axel Linke MD,&nbsp;Norman Mangner MD","doi":"10.1016/j.hlc.2024.07.010","DOIUrl":"10.1016/j.hlc.2024.07.010","url":null,"abstract":"<div><h3>Background</h3><div>The use of microaxial percutaneous left ventricular assist devices (pLVADs) in cardiogenic shock (CS) has increased in recent years, despite limited evidence, and data on sex disparities are particularly scarce. This study aimed to compare short-term outcomes between males and females.</div></div><div><h3>Methods</h3><div>Data were retrospectively collected from the Dresden Impella Registry, which is a large, prospective, single-centre registry that consecutively enrolled patients who received microaxial pLVAD. Inclusion criteria were CS due to left ventricular failure with serum lactate &gt;4 mM. Patients with pLVAD other than Impella CP were excluded. The primary endpoint was the composite of all-cause mortality at 30 days or requirement of renal replacement therapy (RRT). Secondary endpoints were the components of the primary endpoint alone. Propensity score matched (PSM) analysis was used to adjust for baseline characteristics.</div></div><div><h3>Results</h3><div>A total of 319 male (69 years; body mass index, 26.7 kg/m<sup>2</sup>) and 113 female patients (74 years; 27.9 kg/m<sup>2</sup>) were included in the study. The primary composite endpoint occurred less frequently in female patients in the unmatched analysis (♂ 75.9% [n=239] vs ♀ 64.4% [n=72]; p=0.040) but not in the PSM analysis (♂ 81.1% [n=73] vs ♀ 68.9% [n=42]; p=0.056). However, females less frequently required RRT in both analyses (♂ 48.2% [n=126] vs ♀ 25.9% [n=25]; p=0.001; PSM: ♂ 49.1% [n=36] vs ♀ 23.3% [n=12]; p=0.007). All-cause mortality did not differ between the cohorts.</div></div><div><h3>Conclusions</h3><div>This study showed no differences in all-cause mortality at 30 days between male and female patients receiving microaxial pLVAD in CS. Larger studies are required to confirm whether female sex is associated with reduced requirement of RRT in CS treated with microaxial pLVAD.</div></div>","PeriodicalId":13000,"journal":{"name":"Heart, Lung and Circulation","volume":"33 12","pages":"Pages 1670-1679"},"PeriodicalIF":2.2,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142377815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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