Hanna W. van Steenbergen, Frank Doornkamp, Stefano Alivernini, John Backlund, Catalin Codreanu, Stanley B. Cohen, Bernard Combe, Andrew P. Cope, Kevin D. Deane, Bryant R. England, Marie Falahee, Pascal H. P. de Jong, Arnd Kleyer, Diane Lacaille, Bertha Maat, Kulveer Mankia, Elise van Mulligen, György Nagy, Liam J. O'Neil, Linda Rodamaker, Ilfita Sahbudin, Dirkjan van Schaardenburg, Alexandre Sepriano, Jose A. P. da Silva, Lukas De Smet, Jeffrey A. Sparks, Ewout W. Steyerberg, Paul Studenic, Elisabeth Wethington, Robert L. Landewé, Karim Raza, Annette H. M. van der Helm-van Mil
{"title":"EULAR/American College of Rheumatology Risk Stratification Criteria for Development of Rheumatoid Arthritis in the Risk Stage of Arthralgia","authors":"Hanna W. van Steenbergen, Frank Doornkamp, Stefano Alivernini, John Backlund, Catalin Codreanu, Stanley B. Cohen, Bernard Combe, Andrew P. Cope, Kevin D. Deane, Bryant R. England, Marie Falahee, Pascal H. P. de Jong, Arnd Kleyer, Diane Lacaille, Bertha Maat, Kulveer Mankia, Elise van Mulligen, György Nagy, Liam J. O'Neil, Linda Rodamaker, Ilfita Sahbudin, Dirkjan van Schaardenburg, Alexandre Sepriano, Jose A. P. da Silva, Lukas De Smet, Jeffrey A. Sparks, Ewout W. Steyerberg, Paul Studenic, Elisabeth Wethington, Robert L. Landewé, Karim Raza, Annette H. M. van der Helm-van Mil","doi":"10.1002/art.43218","DOIUrl":"https://doi.org/10.1002/art.43218","url":null,"abstract":"The field of rheumatoid arthritis (RA) is moving towards identification of and intervention in people at risk of RA, but a validated risk stratification method is lacking. This work was undertaken to develop a risk stratification method for persons presenting with arthralgia considered to be at risk of RA.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"35 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carine Schmidt, François Maillet, Vincent Bondet, Darragh Duffy, Luc Mouthon, Benjamin Chaigne, Mathieu P Rodero
{"title":"Circulating interferon alpha protein measured with digital ELISA as a biomarker for modified Rodnan skin score progression in limited systemic sclerosis: comment on the article from Di Donato et al","authors":"Carine Schmidt, François Maillet, Vincent Bondet, Darragh Duffy, Luc Mouthon, Benjamin Chaigne, Mathieu P Rodero","doi":"10.1002/art.43226","DOIUrl":"https://doi.org/10.1002/art.43226","url":null,"abstract":"‐","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"142 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges and Future Directions in Machine Learning for Osteoarthritis Prediction ‐ Reply to the comments by Professor Takefuji","authors":"Zijian Kang, Sheng‐Ming Dai","doi":"10.1002/art.43225","DOIUrl":"https://doi.org/10.1002/art.43225","url":null,"abstract":"","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"61 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Ringold,Mei-Sing Ong,George Tomlinson,Marc D Natter,Laura E Schanberg,Vincent Del Gaizo,Brian M Feldman,Katherine L Murphy,Yukiko Kimura,
{"title":"Three-Year Outcomes and Latent Class Trajectory Analysis of the Childhood Arthritis and Rheumatology Research Alliance Polyarticular JIA Consensus Treatment Plans Study.","authors":"Sarah Ringold,Mei-Sing Ong,George Tomlinson,Marc D Natter,Laura E Schanberg,Vincent Del Gaizo,Brian M Feldman,Katherine L Murphy,Yukiko Kimura,","doi":"10.1002/art.43216","DOIUrl":"https://doi.org/10.1002/art.43216","url":null,"abstract":"OBJECTIVETo assess the impact of differences in the timing of initial biologic DMARD (bDMARD) therapy using the CARRA STOP-JIA polyarticular JIA (pJIA) consensus treatment plans (CTPs) study on outcomes through 3 years.METHODSSTOP-JIA participants with CARRA Registry follow-up through 3 years were eligible. Outcomes included ACR clinically inactive disease (CID) off glucocorticoids, clinical Juvenile Arthritis Disease Activity Score (10 joints) inactive disease (cJADAS-10-ID: cJADAS-10≤2.5), clinical remission on medication (CRM), and proportion of time in CID and/or cJADAS-10-ID. Latent class trajectory modeling (LCTM) was applied to identify participant subgroups sharing similar disease courses over this period.RESULTS297 participants were included (n=190 Step Up [SU], 76 Early Combination [EC], 31 Biologic First [BF]). At the 3-year visit, CID was achieved by 35%, 42% and 44%, respectively (p=0.35 for SU versus EC). EC was superior to SU in achieving CRM (59.9% vs. 40.6%; p=0.012), time spent in CID (38% versus 30%; p=0.04) and cJADAS-10-ID (51% versus 41%; p=0.02). Slow, moderate, and rapid improvement trajectories were identified by LCTM; bDMARD initiation within the first (OR 5.33) or second (OR 2.67) month from baseline was associated with the rapid improvement trajectory.CONCLUSIONSEC was superior to SU across 3 years for outcomes reflecting time spent in lower disease activity. Starting bDMARD within 2 months predicted rapid improvement and maintenance of inactive disease. These results support the hypothesis that early bDMARD initiation reduces overall disease burden in pJIA.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"76 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143932443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yongdong Zhao, Melissa S. Oliver, Anja Schnabel, Eveline Y. Wu, Zhaoyi Wang, Achille Marino, Cassyanne L. Aguiar, Jonathan D. Akikusa, Ummusen Kaya Akca, Beverley Almeida, Simone Appenzeller, Erin Balay-Dustrude, Ozge Basaran, Matthew L. Basiaga, Yelda Bilginer, David A. Cabral, Martina Capponi, Nathan Donaldson, Bugra Han Egeli, Emily J. Fox, Antonella Insalaco, Ramesh S. Iyer, Annette F. Jansson, Inna Kostik, Mikhail Kostik, Leonard K. Kovalick, Katia Tomie Kozu, Sivia K. Lapidus, Tzielan C. Lee, Aleksander Lenert, Kamran Mahmood, Edoardo Marrani, Doaa Mosad Mosa, Ian Muse, Alexander Mushkin, Katherine D. Nowicki, Farzana Nuruzzaman, Karen Onel, Manuela Pardeo, Trang Sophia Pham, Lauren Potts, Athimalaipet V. Ramanan, Angelo Ravelli, Nathan D. Rogers, Andrew W. Grim, Micol Romano, Natalie Rosenwasser, Takashi Shawn Sato, Gabriele Simonini, Jennifer B. Soep, Sara M. Stern, Timmy Strauss, Angela Taneja Kohli, Alexander C. Theos, Lori B. Tucker, Leslie F. Vogel, Shima Yasin, Stephen C. Wong, Katerina Bouchalova, Alison M. Hendry, Kevin C. Cain, Hermann J. Girschick, Fatma Dedeoglu, Christian M. Hedrich, Ronald M. Laxer, Polly J. Ferguson, Raymond Naden, Seza Ozen
{"title":"EULAR/American College of Rheumatology Classification Criteria for Pediatric Chronic Nonbacterial Osteomyelitis","authors":"Yongdong Zhao, Melissa S. Oliver, Anja Schnabel, Eveline Y. Wu, Zhaoyi Wang, Achille Marino, Cassyanne L. Aguiar, Jonathan D. Akikusa, Ummusen Kaya Akca, Beverley Almeida, Simone Appenzeller, Erin Balay-Dustrude, Ozge Basaran, Matthew L. Basiaga, Yelda Bilginer, David A. Cabral, Martina Capponi, Nathan Donaldson, Bugra Han Egeli, Emily J. Fox, Antonella Insalaco, Ramesh S. Iyer, Annette F. Jansson, Inna Kostik, Mikhail Kostik, Leonard K. Kovalick, Katia Tomie Kozu, Sivia K. Lapidus, Tzielan C. Lee, Aleksander Lenert, Kamran Mahmood, Edoardo Marrani, Doaa Mosad Mosa, Ian Muse, Alexander Mushkin, Katherine D. Nowicki, Farzana Nuruzzaman, Karen Onel, Manuela Pardeo, Trang Sophia Pham, Lauren Potts, Athimalaipet V. Ramanan, Angelo Ravelli, Nathan D. Rogers, Andrew W. Grim, Micol Romano, Natalie Rosenwasser, Takashi Shawn Sato, Gabriele Simonini, Jennifer B. Soep, Sara M. Stern, Timmy Strauss, Angela Taneja Kohli, Alexander C. Theos, Lori B. Tucker, Leslie F. Vogel, Shima Yasin, Stephen C. Wong, Katerina Bouchalova, Alison M. Hendry, Kevin C. Cain, Hermann J. Girschick, Fatma Dedeoglu, Christian M. Hedrich, Ronald M. Laxer, Polly J. Ferguson, Raymond Naden, Seza Ozen","doi":"10.1002/art.43137","DOIUrl":"https://doi.org/10.1002/art.43137","url":null,"abstract":"To develop and validate classification criteria for pediatric chronic nonbacterial osteomyelitis (CNO) jointly supported by EULAR and the American College of Rheumatology (ACR).","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"117 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Di Donato, Christopher P. Denton, Francesco Del Galdo
{"title":"Reply to: Circulating interferon alpha protein measured with digital ELISA as a biomarker for modified Rodnan skin score progression in limited systemic sclerosis: comment on the article from Di Donato et al","authors":"Stefano Di Donato, Christopher P. Denton, Francesco Del Galdo","doi":"10.1002/art.43223","DOIUrl":"https://doi.org/10.1002/art.43223","url":null,"abstract":"","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"1 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Limitations of Machine Learning-Based Feature Importance in Osteoarthritis Biomarker Discovery","authors":"Yoshiyasu Takefuji","doi":"10.1002/art.43222","DOIUrl":"https://doi.org/10.1002/art.43222","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"68 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Baptiste Chevet, Aghiles Souki, Emmanuel Nowak, Guillermo Carvajal-Alegria, Emmanuelle Dernis, Christophe Richez, Marie-Elise Truchetet, Daniel Wendling, Eric Toussirot, Aleth Perdriger, Jacques-Eric Gottenberg, Renaud Felten, Bruno Fautrel, Anne Lohse, Laurent Chiche, Pascal Hilliquin, Catherine Le Henaff, Benjamin Dervieux, Guillaume Direz, Isabelle Chary-Valckenaere, Divi Cornec, Dewi Guellec, Thierry Marhadour, Alain Saraux, Valérie Devauchelle-Pensec
{"title":"Maintenance of remission after tocilizumab withdrawal in patients with glucocorticoid-dependent polymyalgia rheumatica","authors":"Baptiste Chevet, Aghiles Souki, Emmanuel Nowak, Guillermo Carvajal-Alegria, Emmanuelle Dernis, Christophe Richez, Marie-Elise Truchetet, Daniel Wendling, Eric Toussirot, Aleth Perdriger, Jacques-Eric Gottenberg, Renaud Felten, Bruno Fautrel, Anne Lohse, Laurent Chiche, Pascal Hilliquin, Catherine Le Henaff, Benjamin Dervieux, Guillaume Direz, Isabelle Chary-Valckenaere, Divi Cornec, Dewi Guellec, Thierry Marhadour, Alain Saraux, Valérie Devauchelle-Pensec","doi":"10.1002/art.43221","DOIUrl":"https://doi.org/10.1002/art.43221","url":null,"abstract":"The SEMAPHORE trial evaluated the efficacy and safety of tocilizumab (TCZ) in glucocorticoid (GC)-dependent polymyalgia rheumatica (PMR). TCZ reduced GC use and disease activity at 24 weeks.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"106 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte-García, Linda T. Hiraki, Brad H. Rovin, Mary Beth F. Son, Anthony Alvarado, Cynthia Aranow, April Barnado, Anna Broder, Hermine I. Brunner, Vaidehi Chowdhary, Gabriel Contreras, Christele Felix, Elizabeth D. Ferucci, Keisha L. Gibson, Aimee O. Hersh, Peter M. Izmirly, Kenneth Kalunian, Diane Kamen, Brandi Rollins, Benjamin J. Smith, Asha Thomas, Homa Timlin, Daniel J. Wallace, Michael Ward, Muayad Azzam, Christie M. Bartels, Joanne S. Cunha, Kimberly DeQuattro, Andrea Fava, Gabriel Figueroa-Parra, Shivani Garg, Jessica Greco, Maria C. Cuéllar-Gutiérrez, Priyanka Iyer, Andrew S. Johannemann, April Jorge, Shanthini Kasturi, Hassan Kawtharany, Jana Khawandi, Kyriakos A. Kirou, Alexandra Legge, Kelly V. Liang, Megan M. Lockwood, Alain Sanchez-Rodriguez, Marat Turgunbaev, Jessica N. Williams, Amy S. Turner, Reem A. Mustafa
{"title":"2024 American College of Rheumatology (ACR) Guideline for the Screening, Treatment, and Management of Lupus Nephritis","authors":"Lisa R. Sammaritano, Anca Askanase, Bonnie L. Bermas, Maria Dall'Era, Alí Duarte-García, Linda T. Hiraki, Brad H. Rovin, Mary Beth F. Son, Anthony Alvarado, Cynthia Aranow, April Barnado, Anna Broder, Hermine I. Brunner, Vaidehi Chowdhary, Gabriel Contreras, Christele Felix, Elizabeth D. Ferucci, Keisha L. Gibson, Aimee O. Hersh, Peter M. Izmirly, Kenneth Kalunian, Diane Kamen, Brandi Rollins, Benjamin J. Smith, Asha Thomas, Homa Timlin, Daniel J. Wallace, Michael Ward, Muayad Azzam, Christie M. Bartels, Joanne S. Cunha, Kimberly DeQuattro, Andrea Fava, Gabriel Figueroa-Parra, Shivani Garg, Jessica Greco, Maria C. Cuéllar-Gutiérrez, Priyanka Iyer, Andrew S. Johannemann, April Jorge, Shanthini Kasturi, Hassan Kawtharany, Jana Khawandi, Kyriakos A. Kirou, Alexandra Legge, Kelly V. Liang, Megan M. Lockwood, Alain Sanchez-Rodriguez, Marat Turgunbaev, Jessica N. Williams, Amy S. Turner, Reem A. Mustafa","doi":"10.1002/art.43212","DOIUrl":"https://doi.org/10.1002/art.43212","url":null,"abstract":"The objective is to provide evidence-based and expert guidance for the screening, treatment, and management of lupus nephritis.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"25 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143915563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elise van Mulligen, Jon T Giles, Angelique EAM Weel
{"title":"Tapering in Rheumatoid Arthritis: A Path to Predict Flares","authors":"Elise van Mulligen, Jon T Giles, Angelique EAM Weel","doi":"10.1002/art.43224","DOIUrl":"https://doi.org/10.1002/art.43224","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"106 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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