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Efficacy of BI 655064 in improving renal outcome in patients with lupus nephritis
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-02-17 DOI: 10.1002/art.43132
Mi Zhou, Ru-yang Jing, Li-xue Yin
{"title":"Efficacy of BI 655064 in improving renal outcome in patients with lupus nephritis","authors":"Mi Zhou, Ru-yang Jing, Li-xue Yin","doi":"10.1002/art.43132","DOIUrl":"https://doi.org/10.1002/art.43132","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"85 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143427387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Discovery of a Novel Missense Variant in NLRP3 Causing Atypical Cryopyrin‐Associated Periodic Syndromes With Hearing Loss as the Primary Presentation, Responsive to Anti‐Interleukin‐1 Therapy
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-02-12 DOI: 10.1002/art.43112
{"title":"Correction to: Discovery of a Novel Missense Variant in NLRP3 Causing Atypical Cryopyrin‐Associated Periodic Syndromes With Hearing Loss as the Primary Presentation, Responsive to Anti‐Interleukin‐1 Therapy","authors":"","doi":"10.1002/art.43112","DOIUrl":"https://doi.org/10.1002/art.43112","url":null,"abstract":"","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"47 3 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143393147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Target trial emulations of SGLT2 inhibitors show benefit in SLE!
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-02-10 DOI: 10.1002/art.43130
Janet Pope, Derin Karacabeyli, J. Antonio Aviña-Zubieta
{"title":"Target trial emulations of SGLT2 inhibitors show benefit in SLE!","authors":"Janet Pope, Derin Karacabeyli, J. Antonio Aviña-Zubieta","doi":"10.1002/art.43130","DOIUrl":"https://doi.org/10.1002/art.43130","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"15 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SLAMF4 orchestrates the cytotoxic response of CD4+ T cells in rheumatoid arthritis
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-02-02 DOI: 10.1002/art.43124
Mégane Lacaud, Houda-Ghozlane Bouzidi, Mylène Petit, Magali Breckler, Delphine Lemeiter, Johanna Sigaux, Elodie Rivière, Luca Semerano, Marie-Christophe Boissier, Natacha Bessis, Jérôme Biton
{"title":"SLAMF4 orchestrates the cytotoxic response of CD4+ T cells in rheumatoid arthritis","authors":"Mégane Lacaud, Houda-Ghozlane Bouzidi, Mylène Petit, Magali Breckler, Delphine Lemeiter, Johanna Sigaux, Elodie Rivière, Luca Semerano, Marie-Christophe Boissier, Natacha Bessis, Jérôme Biton","doi":"10.1002/art.43124","DOIUrl":"https://doi.org/10.1002/art.43124","url":null,"abstract":"This study aimed to assess whether signaling lymphocytic activation molecule family receptors (SLAMFs) are involved in the shaping of the pathological response of CD4<sup>+</sup> T cells in rheumatoid arthritis (RA).","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"38 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143077159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to CD19 Chimeric Antigen Receptor T Cell Treatment: Unraveling the Role of B Cells in Systemic Lupus Erythematosus
IF 11.4 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-31 DOI: 10.1002/art.43080
{"title":"Correction to CD19 Chimeric Antigen Receptor T Cell Treatment: Unraveling the Role of B Cells in Systemic Lupus Erythematosus","authors":"","doi":"10.1002/art.43080","DOIUrl":"10.1002/art.43080","url":null,"abstract":"<p>Correction to “Figure 3. Key insights from CAR T cell therapy in SLE.”</p><p>Arthritis &amp; Rheumatology</p><p>Vol. 76, No. 4, April 2024, pp 497–504</p><p>DOI 10.1002/art.42784</p><p>In the middle panel of this figure, the plasma cells are identified as “CD19+CD20-” (same as the plasmablasts) – but one key point of the paper is that they are not CD19+. It should read “CD19– CD20–”.</p><p>Also, in the same panel and figure, measles is misspelled as “measels.”</p><p>Please see below for the corrected version of this figure.</p><p>We apologize for this error.</p>","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"77 3","pages":"365"},"PeriodicalIF":11.4,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.43080","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Journal Club
IF 11.4 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-30 DOI: 10.1002/art.42872
{"title":"Journal Club","authors":"","doi":"10.1002/art.42872","DOIUrl":"10.1002/art.42872","url":null,"abstract":"","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"77 2","pages":""},"PeriodicalIF":11.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.42872","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Connections
IF 11.4 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-30 DOI: 10.1002/art.42874
{"title":"Clinical Connections","authors":"","doi":"10.1002/art.42874","DOIUrl":"10.1002/art.42874","url":null,"abstract":"","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"77 2","pages":""},"PeriodicalIF":11.4,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.42874","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143072153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genome-wide aggregated trans- effects analysis identifies genes encoding immune checkpoints as core genes for rheumatoid arthritis
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-29 DOI: 10.1002/art.43125
Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Megan Sutcliffe, Seema Sharma, Cankut Cubuk, Myles Lewis, Costantino Pitzalis, Anne Barton, Paul M McKeigue
{"title":"Genome-wide aggregated trans- effects analysis identifies genes encoding immune checkpoints as core genes for rheumatoid arthritis","authors":"Athina Spiliopoulou, Andrii Iakovliev, Darren Plant, Megan Sutcliffe, Seema Sharma, Cankut Cubuk, Myles Lewis, Costantino Pitzalis, Anne Barton, Paul M McKeigue","doi":"10.1002/art.43125","DOIUrl":"https://doi.org/10.1002/art.43125","url":null,"abstract":"The sparse effector “omnigenic” hypothesis postulates that the polygenic effects of common SNPs on a typical complex trait are mediated by <i>trans</i>- effects that coalesce on expression of a relatively sparse set of core genes. The objective of this study was to identify core genes for rheumatoid arthritis by testing for association of rheumatoid arthritis with genome-wide aggregated <i>trans</i>- effects (GATE) scores for expression of each gene as transcript in whole blood or as circulating protein levels.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"74 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Type I Interferon Score predicts clinically meaningful disease progression in limited cutaneous Systemic Sclerosis
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-29 DOI: 10.1002/art.43120
Stefano Di Donato, Rebecca Ross, Ranjitha Karanth, Vishal Kakkar, Enrico De Lorenzis, Lesley-Anne Bissell, Kristina Clark, Philip Yee, Christopher P. Denton, Francesco Del Galdo
{"title":"Serum Type I Interferon Score predicts clinically meaningful disease progression in limited cutaneous Systemic Sclerosis","authors":"Stefano Di Donato, Rebecca Ross, Ranjitha Karanth, Vishal Kakkar, Enrico De Lorenzis, Lesley-Anne Bissell, Kristina Clark, Philip Yee, Christopher P. Denton, Francesco Del Galdo","doi":"10.1002/art.43120","DOIUrl":"https://doi.org/10.1002/art.43120","url":null,"abstract":"To assess the value of serum Type I Interferon (IFN) score in predicting clinically meaningful progression in limited cutaneous systemic sclerosis (lcSSc) using a novel composite endpoint adopted from the MINIMISE clinical trial.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"32 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143056962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unexplored Limitations in the SLEek Trial of Upadacitinib and Elsubrutinib 乌达帕替尼和埃舒鲁替尼的 SLEek 试验中尚未发现的局限性
IF 13.3 1区 医学
Arthritis & Rheumatology Pub Date : 2025-01-27 DOI: 10.1002/art.43122
Qianyu Guo, Junkang Zhao, James Cheng-Chung Wei, Li-yun Zhang
{"title":"Unexplored Limitations in the SLEek Trial of Upadacitinib and Elsubrutinib","authors":"Qianyu Guo, Junkang Zhao, James Cheng-Chung Wei, Li-yun Zhang","doi":"10.1002/art.43122","DOIUrl":"https://doi.org/10.1002/art.43122","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":129,"journal":{"name":"Arthritis & Rheumatology","volume":"59 1","pages":""},"PeriodicalIF":13.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143044708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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