Heredity最新文献_第2页

Expansion of satellite DNAs derived from transposable elements in beetles with reduced diploid numbers 二倍体数量减少的甲虫中转座因子衍生的卫星dna的扩增。

IF 3.9 2区生物学

Heredity Pub Date : 2025-08-24 DOI: 10.1038/s41437-025-00790-w

José M. Rico-Porras, Pablo Mora, Ana E. Gasparotto, Vanessa B. Bardella, Teresa Palomeque, Pedro Lorite, Diogo C. Cabral-de-Mello

{"title":"Expansion of satellite DNAs derived from transposable elements in beetles with reduced diploid numbers","authors":"José M. Rico-Porras, Pablo Mora, Ana E. Gasparotto, Vanessa B. Bardella, Teresa Palomeque, Pedro Lorite, Diogo C. Cabral-de-Mello","doi":"10.1038/s41437-025-00790-w","DOIUrl":"10.1038/s41437-025-00790-w","url":null,"abstract":"Repetitive DNA sequences are ubiquitous in eukaryotic genomes, significantly influencing their structure, function, and evolution. They can facilitate genomic rearrangements, contributing to chromosomal and genomic diversity. Chrysomelidae (Coleoptera) beetles are known for their highly diverse karyotypes and heterochromatin distribution. In this study, we advanced the understanding of the intricate relationship between satellite DNA-like sequences (named here solely as satDNA) and genome organization/reshuffling using three species of Eumolpinae chrysomelids. We investigated the satellitomes of three species with divergent karyotypes that had undergone independent chromosomal fusions: Colaspis laeta (2n = 22, Xyp), with a conserved karyotype; Endocephalus bigatus (2n = 10, neo-XY); and Iphimeis dives (2n = 14, neo-XY). Our comparative analysis revealed highly divergent patterns of satDNA origin, organization, and evolution. In species with reduced chromosome numbers and neo-sex chromosomes, we observed a high abundance of transposable element-related (TE-related) satDNAs. In Colaspis laeta, the sex chromosomes (Xyp) showed an advanced level of differentiation. However, in the species with a reduction in diploid number, such a level of differential enrichment of repetitive DNAs was not observed in the sex chromosomes, indicating an early stage of differentiation. Our findings support the hypothesis that chromosomal rearrangements and reorganization of repetitive DNA sequences are connected, with extensive reshuffling observed in species with reduced diploid numbers. Moreover, the data reinforce the involvement of TEs in satDNA origin, which could spread widely throughout the genome, including euchromatic areas. This study provides new insights into the evolutionary dynamics of repetitive DNAs in non-model species, emphasizing the impact of chromosomal rearrangements on genome architecture and evolution.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 9","pages":"529-541"},"PeriodicalIF":3.9,"publicationDate":"2025-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genome sequence analysis provides evidence that a boreal crustacean colonised Svalbard well before the ongoing Atlantification of the Arctic 基因组序列分析提供了证据，证明在北极大西洋化之前，一种北方甲壳类动物就已经在斯瓦尔巴群岛定居了。

IF 3.9 2区生物学

Heredity Pub Date : 2025-08-23 DOI: 10.1038/s41437-025-00793-7

Hedvig Kriszta Csapó, Jan Marcin Weslawski, Nova Mieszkowska, Ida Dahl-Hansen, Michael Gantsevich, Michal Grabowski, Nicolas Bierne

{"title":"Genome sequence analysis provides evidence that a boreal crustacean colonised Svalbard well before the ongoing Atlantification of the Arctic","authors":"Hedvig Kriszta Csapó, Jan Marcin Weslawski, Nova Mieszkowska, Ida Dahl-Hansen, Michael Gantsevich, Michal Grabowski, Nicolas Bierne","doi":"10.1038/s41437-025-00793-7","DOIUrl":"10.1038/s41437-025-00793-7","url":null,"abstract":"The study of present-day species distributions often raises questions about historical demography. A particularly interesting phenomenon to put in historical context is contemporary human-induced atlantification and its role in reshaping Arctic ecosystems. Despite this, the colonisation history of the Arctic remains generally understudied. In this study, we investigated the demographic history of the northern acorn barnacle, Semibalanus balanoides, a typically boreal species on the Svalbard Archipelago. Our focus was to determine the source and timing of its colonisation of this Arctic archipelago. Using low-coverage whole-genome sequence data, we evaluated two competing hypotheses: whether S. balanoides populations colonised Svalbard through ancient natural processes before the Anthropocene, or if their appearance is more recent, either natural or a consequence of growing anthropogenic influences, such as increased connectivity and global warming. Our results suggest that this boreal species expanded into the Arctic during the later phase of the Holocene Thermal Optimum, well before human-induced climate change.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 9","pages":"558-566"},"PeriodicalIF":3.9,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41437-025-00793-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantifying genetic and genotypic gain gaps in Eucalyptus: the hidden cost of ignoring inbreeding and dominance 量化桉树的遗传和基因型增益差距：忽视近交和优势的隐性成本。

IF 3.9 2区生物学

Heredity Pub Date : 2025-08-21 DOI: 10.1038/s41437-025-00792-8

Marcio J. Araujo, David Bush, Evandro V. Tambarussi

{"title":"Quantifying genetic and genotypic gain gaps in Eucalyptus: the hidden cost of ignoring inbreeding and dominance","authors":"Marcio J. Araujo, David Bush, Evandro V. Tambarussi","doi":"10.1038/s41437-025-00792-8","DOIUrl":"10.1038/s41437-025-00792-8","url":null,"abstract":"Understanding the mating system of Eucalyptus species is necessary to accurately estimate genetic parameters and improve breeding programs. Eucalyptus species often exhibit mixed mating systems, leading to complex relationships among progenies. Traditional tree breeding programs that assume a half-sibling relationship for open-pollinated (OP) trials may overestimate genetic gains by neglecting the effects of inbreeding and dominance. This study focuses on Eucalyptus pellita, a species with a mixed mating system, to quantify the impact of selfing and dominance on breeding strategies. We simulated OP trial growth data for 100 randomly selected families in a randomized complete block design, using published estimated parameters for diameter at breast height (DBH). Our analysis indicated that marker-based models, particularly those incorporating dominance effects, provide more accurate genetic parameter estimates and larger predicted genetic gains than pedigree-based models. These results reveal pronounced genetic and genotypic gain gaps when traditional models are employed, underscoring the imperative for integrating dominance-informed genomic selection strategies. Thus, our study provides essential guidance for optimizing breeding programs to sustainably enhance productivity and genetic quality in Eucalyptus plantations.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 9","pages":"542-557"},"PeriodicalIF":3.9,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41437-025-00792-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144952045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Beyond inversions and deletions: the evolutionary and functional insights from translocations, fissions, and fusions in animal genomes. 超越倒置和缺失：动物基因组易位、分裂和融合的进化和功能见解。

IF 3.9 2区生物学

Heredity Pub Date : 2025-08-01 DOI: 10.1038/s41437-025-00785-7

Célian Diblasi, Marie Saitou

{"title":"Beyond inversions and deletions: the evolutionary and functional insights from translocations, fissions, and fusions in animal genomes.","authors":"Célian Diblasi, Marie Saitou","doi":"10.1038/s41437-025-00785-7","DOIUrl":"10.1038/s41437-025-00785-7","url":null,"abstract":"Structural variants, such as deletions, insertions, and inversions, have been increasingly recognized as important drivers of genome evolution, in the era of high-throughput sequencing. However, large-scale chromosomal rearrangements involving multiple chromosomes, including translocations, chromosomal fusions, and fissions, remain relatively understudied, especially outside of clinical and model systems, due to challenges in their detection and analysis. While the earlier understanding of translocations came from human cancer genomics, how such mutations have shaped genome evolution across animal lineages remains insufficiently understood. Recent advances in long-read sequencing, chromosome-level assemblies, and 3D genome conformation techniques are now revealing the prevalence and evolutionary significance of these large genomic structural rearrangements. Translocations can relocate genes into new regulatory environments, chromosome fusions can suppress recombination, and chromosome fissions can restructure chromosomal architecture, modifying the spatial and regulatory context of genes, thereby shaping evolutionary potential. Transposable elements further complicate this landscape by both promoting chromosomal instability and serving as substrates for rearrangement. Together, these changes can drive adaptive evolution, shape karyotype evolution, and contribute to sex chromosome turnover.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144764839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring evolutionary mechanisms of genomic divergence in marine intertidal limpets 探讨海洋潮间带帽贝基因组分化的进化机制。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-30 DOI: 10.1038/s41437-025-00782-w

Paulina Carimán, Marie-Laure Guillemin, Emily C. Giles, Gabriela Narváez, Ana V. Suescún, Pablo Sáenz-Agudelo

{"title":"Exploring evolutionary mechanisms of genomic divergence in marine intertidal limpets","authors":"Paulina Carimán, Marie-Laure Guillemin, Emily C. Giles, Gabriela Narváez, Ana V. Suescún, Pablo Sáenz-Agudelo","doi":"10.1038/s41437-025-00782-w","DOIUrl":"10.1038/s41437-025-00782-w","url":null,"abstract":"Decades of research in population genetics have revealed that genetic divergence between populations and species is not uniformly distributed throughout the genome but rather exhibits a high degree of heterogeneity. Two main conceptual models—allopatric divergence and divergence with gene flow—have been proposed to explain this variability under natural selection. Here, we investigate patterns of genomic divergence in three marine limpet species, Scurria scurra, Scurria araucana, and Scurria ceciliana, across two major biogeographic breaks (30–34°S and 41–43°S). Genomic divergence varied among species, even between the two sympatric species S. scurra and S. araucana, which exhibited heterogeneous divergence patterns across the 30–34°S range. In S. ceciliana, the southernmost species (41–43°S), divergence was shaped by a combination of allopatric divergence and divergence with gene flow. This was unexpected given that its evolutionary history suggests past isolation in glacial refugia, which would have limited gene flow. However, the observed genomic divergence indicates that genetic exchange occurred between populations, challenging previous assumptions about its evolutionary dynamics. Divergence patterns appear species-specific, with few shared genomic regions, though more similarities were found among the sister species S. scurra and S. araucana. In highly divergent regions, genes associated with lipid metabolism were identified in S. scurra and S. araucana, whereas genes related to oxidative stress response and mitochondrial functions were found in S. ceciliana. These findings suggest that genomic divergence is not entirely stochastic but may be shaped by different selective pressures in each species, potentially reflecting adaptation to distinct ecological conditions.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 8","pages":"500-511"},"PeriodicalIF":3.9,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Germline-restricted chromosome of songbirds has different centromere compared to regular chromosomes. 鸣禽种系限制性染色体与正常染色体具有不同的着丝粒。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-30 DOI: 10.1038/s41437-025-00779-5

Jakub Rídl, Dmitrij Dedukh, Zuzana Halenková, Stephen A Schlebusch, Vladimír Beneš, Mireia Osuna Lopez, Tomasz S Osiejuk, Francisco J Ruiz-Ruano, Alexander Suh, Tomáš Albrecht, Jiří Reif, Radka Reifová

{"title":"Germline-restricted chromosome of songbirds has different centromere compared to regular chromosomes.","authors":"Jakub Rídl, Dmitrij Dedukh, Zuzana Halenková, Stephen A Schlebusch, Vladimír Beneš, Mireia Osuna Lopez, Tomasz S Osiejuk, Francisco J Ruiz-Ruano, Alexander Suh, Tomáš Albrecht, Jiří Reif, Radka Reifová","doi":"10.1038/s41437-025-00779-5","DOIUrl":"https://doi.org/10.1038/s41437-025-00779-5","url":null,"abstract":"Centromeres are an important part of chromosomes which direct chromosome segregation during cell division. Their modifications can therefore explain the unusual mitotic and meiotic behaviour of certain chromosomes, such as the germline-restricted chromosome (GRC) of songbirds. This chromosome is eliminated from somatic cells during early embryogenesis and later also from male germ cells during spermatogenesis. Although the mechanism of elimination is not yet known, it is possible that it involves a modification of the centromeric sequence on the GRC, resulting in problems with the attachment of this chromosome to the mitotic or meiotic spindle and its lagging during anaphase, which eventually leads to its elimination from the nucleus. However, the repetitive nature and rapid evolution of centromeres make their identification and comparative analysis across species and chromosomes challenging. Here, we used a combination of cytogenetic and genomic approaches to identify the centromeric sequences of two closely related songbird species, the common nightingale (Luscinia megarhynchos) and the thrush nightingale (L. luscinia). We found a 436-bp satellite repeat present in the centromeric regions of all regular chromosomes (i.e., autosomes and sex chromosomes), making it a strong candidate for the centromeric repeat. This centromeric repeat was highly similar between the two nightingale species. Interestingly, hybridization of the probe to this satellite repeat on meiotic spreads suggested that this repeat is missing on the GRC. Our results indicate that the change of the centromeric sequence may underlie the unusual inheritance and programmed DNA elimination of the GRC in songbirds.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144759971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Both maternal and paternal genotypes modulate Wolbachia-induced cytoplasmic incompatibility in graham bean beetles 母系和父系基因型均可调节沃尔巴克氏体诱导的格雷厄姆豆甲虫细胞质不亲和性。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-30 DOI: 10.1038/s41437-025-00787-5

Yuko Numajiri, Natsuko I. Kondo, Yukihiko Toquenaga, Daisuke Kageyama

{"title":"Both maternal and paternal genotypes modulate Wolbachia-induced cytoplasmic incompatibility in graham bean beetles","authors":"Yuko Numajiri, Natsuko I. Kondo, Yukihiko Toquenaga, Daisuke Kageyama","doi":"10.1038/s41437-025-00787-5","DOIUrl":"10.1038/s41437-025-00787-5","url":null,"abstract":"Cytoplasmic incompatibility (CI) is a phenomenon where embryonic development is disrupted–often leading to complete failure–when the female parent lacks the symbiont strain carried by the male parent. This mechanism, employed by maternally transmitted symbionts such as Wolbachia, facilitates their rapid spread within a host population. CI has significant potential as a tool for achieving population replacement or suppression, particularly targeting disease vectors and agricultural pests. While complete expression of CI is ideal for such applications, its intensity can vary. Despite extensive research on the symbiont genotypes, the influence of host genetic background on CI expression remains poorly understood. Here, we found that in the bean beetle Callosobruchus analis, the Wolbachia strain wCana2 induces weak CI in its native nuclear background but strong CI in a previously unassociated nuclear background. Crossing experiments reveal that the nuclear backgrounds of both male and female parents can significantly affect CI expression independent of Wolbachia titres in C. analis. These findings uncover novel perspectives on the host-symbiont interactions underlying CI and highlight the complexities to be addressed for its practical application.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 8","pages":"512-518"},"PeriodicalIF":3.9,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of mating system and adaptedness on the evolution of fitness and mtDNA copy number in mitonuclear mismatched C. elegans. 交配制度和适应性对有丝核错配线虫适合度和mtDNA拷贝数进化的影响。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-28 DOI: 10.1038/s41437-025-00786-6

Zachary P Dietz, Devshuvam Banerji, Jennifer A Sullins, Brent W Bever, Stephen F Christy, Ulfar Bergthorsson, Vaishali Katju, Suzanne Estes

{"title":"Effects of mating system and adaptedness on the evolution of fitness and mtDNA copy number in mitonuclear mismatched C. elegans.","authors":"Zachary P Dietz, Devshuvam Banerji, Jennifer A Sullins, Brent W Bever, Stephen F Christy, Ulfar Bergthorsson, Vaishali Katju, Suzanne Estes","doi":"10.1038/s41437-025-00786-6","DOIUrl":"10.1038/s41437-025-00786-6","url":null,"abstract":"Metabolic functioning in nearly all eukaryotes relies on molecular machinery dual-encoded by mitochondrial DNA (mtDNA) and nuclear DNA (nDNA) genomes. The two genomes have sustained an extraordinary degree of cooperation across evolutionary time, preserving the capacity for indispensable processes including oxidative phosphorylation and ATP production, which in turn influence many fitness-related traits. How this cooperation is maintained when one member of the pair is debilitated by deleterious mutation is poorly understood, as is the influence of mutation location (mtDNA or nDNA), mating system, or the potentially compensatory effects of mtDNA copy number changes on the process. We asked whether and to what extent populations experiencing mitonuclear mismatch can recover ancestral levels of fitness by allowing C. elegans nematodes containing either mitochondrial or nuclear mutations of electron transport chain (ETC) genes to evolve under three mating systems-facultatively outcrossing (wildtype), obligately selfing, and obligately outcrossing-for 60 generations. In alignment with evolutionary theory, we observed an inverse relationship between the magnitude of fitness recovery and the ancestral fitness level of strains with the latter outweighing any effect of mating system. We interpret these findings in light of previously reported male frequency evolution in the same mutant lines. The relationship between the amount of fitness evolution and change in mtDNA copy number was influenced by strains' ETC mutant background and its interaction with mating system. To our knowledge, this work provides the first direct test of the effects of reproductive mode and evolution under mitonuclear mismatch on the population dynamics of mtDNA genomes.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144730062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impacts of temperature on recombination rate and meiotic success in thermotolerant and cold-tolerant yeast species 温度对耐热和耐寒酵母重组率和减数分裂成功率的影响。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-26 DOI: 10.1038/s41437-025-00778-6

Jessica McNeill, Nathan Brandt, Enrique J. Schwarzkopf, Mili Jimenez, Caiti Smukowski Heil

{"title":"Impacts of temperature on recombination rate and meiotic success in thermotolerant and cold-tolerant yeast species","authors":"Jessica McNeill, Nathan Brandt, Enrique J. Schwarzkopf, Mili Jimenez, Caiti Smukowski Heil","doi":"10.1038/s41437-025-00778-6","DOIUrl":"10.1038/s41437-025-00778-6","url":null,"abstract":"Meiosis is required for the formation of gametes in all sexually reproducing species and the process is well conserved across the tree of life. However, meiosis is sensitive to a variety of external factors, which can impact chromosome pairing, recombination, and fertility. For example, the optimal temperature for successful meiosis varies between species of plants and animals. This suggests that meiosis is temperature sensitive, and that natural selection may act on variation in meiotic success as organisms adapt to different environmental conditions. To understand how temperature alters the successful completion of meiosis, we utilized two species of the budding yeast Saccharomyces with different temperature preferences: thermotolerant Saccharomyces cerevisiae and cold-tolerant Saccharomyces uvarum. We surveyed three metrics of meiosis: sporulation efficiency, spore viability, and recombination rate in multiple strains of each species. As per our predictions, the proportion of cells that complete meiosis and form spores is temperature sensitive, with thermotolerant S. cerevisiae having a higher temperature threshold for completion of meiosis than cold-tolerant S. uvarum. We confirmed previous observations that S. cerevisiae recombination rate varies between strains and across genomic regions, and add new results that S. uvarum has comparably high recombination rates. We find significant recombination rate plasticity due to temperature in S. cerevisiae and S. uvarum, in agreement with studies in animals and plants. Overall, these results suggest that meiotic thermal sensitivity is associated with organismal thermal tolerance and may even result in temporal reproductive isolation as populations diverge in thermal profiles.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":"134 8","pages":"473-484"},"PeriodicalIF":3.9,"publicationDate":"2025-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41437-025-00778-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144717792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Experimental test of the fitness effects of divergent marine-freshwater chromosomal inversions in stickleback under different salinity conditions. 不同盐度条件下棘鱼不同海水-淡水染色体倒位适合度效应的实验研究。

IF 3.9 2区生物学

Heredity Pub Date : 2025-07-24 DOI: 10.1038/s41437-025-00784-8

Juliana Rodríguez-Fuentes, Nicole Nesvadba, Verena Saladin, Marius Roesti, Catherine L Peichel

{"title":"Experimental test of the fitness effects of divergent marine-freshwater chromosomal inversions in stickleback under different salinity conditions.","authors":"Juliana Rodríguez-Fuentes, Nicole Nesvadba, Verena Saladin, Marius Roesti, Catherine L Peichel","doi":"10.1038/s41437-025-00784-8","DOIUrl":"10.1038/s41437-025-00784-8","url":null,"abstract":"Chromosomal inversions are a type of structural variant that have long interested evolutionary biologists because of their potential role in local adaptation and speciation. However, direct experimental evidence for the fitness consequences of inversions is rare, limiting our ability to dissect the evolutionary forces associated with the spread and maintenance of inversions in natural populations. We tackle this knowledge gap by studying the fitness effects of three chromosomal inversions that consistently differ between marine and freshwater populations of threespine sticklebacks (Gasterosteus aculeatus). Using controlled laboratory crosses, we tested whether inversion genotype influences fitness (measured as survival, standard length, and body condition) across two salinity treatments (freshwater vs saltwater). In both the freshwater and the saltwater treatments, there were no deviations from Mendelian ratios at any of the three inversions. This suggests that there are no intrinsic deleterious effects of these inversions, in contrast to observations from other systems. Overall, there was no effect of inversion genotype on standard length or body size across the two salinity treatments for the chromosome XI and XXI inversions. For the chromosome I inversion, heterozygotes had a slightly lower body condition in the freshwater treatment. Together, these results suggest that the fitness effects of these inversions are not strongly influenced by salinity and that other selective forces might be involved in their evolution. More broadly, these findings highlight the importance of performing empirical tests of fitness effects of chromosomal inversions to better explain their spread and maintenance in nature.","PeriodicalId":12991,"journal":{"name":"Heredity","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0