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[Livid nodule on the nose of a patient with bronchial carcinoma]. 支气管癌患者鼻部的青色结节。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2021-07-24 DOI: 10.1007/s00105-021-04867-5
Julia K Winkler, Holger A Haenssle, Ines Bertlich, Alexander H Enk, Ferdinand Toberer
{"title":"[Livid nodule on the nose of a patient with bronchial carcinoma].","authors":"Julia K Winkler, Holger A Haenssle, Ines Bertlich, Alexander H Enk, Ferdinand Toberer","doi":"10.1007/s00105-021-04867-5","DOIUrl":"https://doi.org/10.1007/s00105-021-04867-5","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"329-331"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00105-021-04867-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39219726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Immunohistochemical analysis of a hypoxia-associated signature in melanomas with positive and negative sentinel lymph nodes : Hypoxia-associated signature of primary cutaneous melanomas]. 【前哨淋巴结阳性和阴性黑色素瘤缺氧相关特征的免疫组织化学分析:原发性皮肤黑色素瘤缺氧相关特征】。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2022-01-07 DOI: 10.1007/s00105-021-04934-x
Ferdinand Toberer, Julia K Winkler, Holger A Haenssle, Monika Heinzel-Gutenbrunner, Alexander Enk, Wolfgang Hartschuh, Peter Helmbold, Heinz Kutzner
{"title":"[Immunohistochemical analysis of a hypoxia-associated signature in melanomas with positive and negative sentinel lymph nodes : Hypoxia-associated signature of primary cutaneous melanomas].","authors":"Ferdinand Toberer,&nbsp;Julia K Winkler,&nbsp;Holger A Haenssle,&nbsp;Monika Heinzel-Gutenbrunner,&nbsp;Alexander Enk,&nbsp;Wolfgang Hartschuh,&nbsp;Peter Helmbold,&nbsp;Heinz Kutzner","doi":"10.1007/s00105-021-04934-x","DOIUrl":"https://doi.org/10.1007/s00105-021-04934-x","url":null,"abstract":"<p><p>Metabolic reprogramming mediated by hypoxia-inducible factors and its downstream targets plays a crucial role in many human malignancies. Excessive proliferation of tumor cells under hypoxic conditions leads to metabolic reprogramming and altered gene expression enabling tumors to adapt to their hypoxic environment. Here we analyzed the metabolic signatures of primary cutaneous melanomas with positive and negative sentinel node status in order to evaluate potential differences in their metabolic signature. We found a positive correlation of the expression of glucose transporter 1 (GLUT-1) with tumor thickness and ulceration in all melanomas with subgroup analyses as well as in the subgroup with a negative sentinel node. Furthermore, the expression of vascular endothelial growth factor (VEGF) was positively correlated with the presence of ulceration in melanomas with positive sentinel node.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"283-290"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964660/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39672218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
["Joy and friendship through research" : On the occasion of the 100th birthday of Prof. Dr. med. Dr. h.c. mult. Otto Braun-Falco]. “研究带来的快乐和友谊”:在医学博士h.c. mult博士诞辰100周年之际。奥托Braun-Falco]。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2022-02-24 DOI: 10.1007/s00105-022-04971-0
Jörg C Prinz, Lars E French
{"title":"[\"Joy and friendship through research\" : On the occasion of the 100th birthday of Prof. Dr. med. Dr. h.c. mult. Otto Braun-Falco].","authors":"Jörg C Prinz,&nbsp;Lars E French","doi":"10.1007/s00105-022-04971-0","DOIUrl":"https://doi.org/10.1007/s00105-022-04971-0","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"245-248"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39950093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Calprotectin-a key for diagnosing chronic inflammatory bowel disease in inflammatory dermatoses? : Three case reports]. 钙护蛋白是炎性皮肤病中诊断慢性炎症性肠病的关键?[3例报告]。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2021-04-21 DOI: 10.1007/s00105-021-04821-5
E Koutra, E Lusmöller, R Stadler
{"title":"[Calprotectin-a key for diagnosing chronic inflammatory bowel disease in inflammatory dermatoses? : Three case reports].","authors":"E Koutra,&nbsp;E Lusmöller,&nbsp;R Stadler","doi":"10.1007/s00105-021-04821-5","DOIUrl":"https://doi.org/10.1007/s00105-021-04821-5","url":null,"abstract":"<p><p>We report on three patients with inflammatory dermatoses as a result of a chronic inflammatory bowel disease (IBD). The diagnosis of IBD was based on the initial determination of the fecal calprotectin value. Although the patients did not report any intestinal complaints, the increased calprotectin value in the stool was the reason for further gastroenterological evaluation. This article highlights the importance of determining the fecal calprotectin value as another parameter in the diagnosis of inflammatory dermatoses.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"303-307"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00105-021-04821-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38897129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
[Characterization of sun protection performance: Quo vadis?] 【防晒性能表征:Quo vadis?】］
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2022-03-25 DOI: 10.1007/s00105-022-04958-x
Uli Osterwalder, Christian Surber
{"title":"[Characterization of sun protection performance: Quo vadis?]","authors":"Uli Osterwalder,&nbsp;Christian Surber","doi":"10.1007/s00105-022-04958-x","DOIUrl":"https://doi.org/10.1007/s00105-022-04958-x","url":null,"abstract":"<p><p>The task of the first sunscreens was to prevent the development of sunburn and, following the spirit of the 1950/1960s, to not impair the tanning of the skin. The need to quantify the protective performance soon arose. Originally with the help of natural-nowadays artificial-sunlight, a method was developed to determine a sun protection factor (SPF). It is formally defined as a ratio between minimum erythema-effective UV dose on sunscreen-protected skin and minimum erythema-effective UV dose on unprotected skin (ISO 24444:2019). Three observations question the suitability of the method. (1) Interlaboratory variability: Despite strict standardization, results of SPF determinations from different laboratories are subject to large variations. (2) Natural vs. artificial sunlight: The radiation spectrum of artificial sunlight differs from that of natural sunlight. SPFs determined with artificial sunlight (as depicted on all sunscreens currently on the market) are significantly too high compared to SPF determination with natural sunlight. (3) Erythema burden: When determining SPF, subjects are exposed to potentially harmful radiation. Against this background alternative methods-in vitro SPF, hybrid diffuse reflectance spectroscopy (HDRS) and in silico calculations-are presented. These have the potential to replace the current method. As an immediate measure, it is recommended to return to the comprehensible description of low, medium, high, and very high protection and in the future to take into account the spectrum of natural sunlight.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":" ","pages":"276-282"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8964537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40328272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
[Pregnant woman with pruritic urticarial plaques on the abdomen]. [腹部瘙痒性荨麻疹斑块的孕妇]。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2021-06-16 DOI: 10.1007/s00105-021-04838-w
Sven-Niklas Burmann, Sara Lausch, Frank Oellig, Alena-Lioba Michalowitz, Alexander Kreuter
{"title":"[Pregnant woman with pruritic urticarial plaques on the abdomen].","authors":"Sven-Niklas Burmann,&nbsp;Sara Lausch,&nbsp;Frank Oellig,&nbsp;Alena-Lioba Michalowitz,&nbsp;Alexander Kreuter","doi":"10.1007/s00105-021-04838-w","DOIUrl":"https://doi.org/10.1007/s00105-021-04838-w","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"326-328"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00105-021-04838-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39241489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Laugier-Hunziker syndrome : A rare differential diagnosis of mucocutaneous hyperpigmentation]. [Laugier-Hunziker综合征:一种罕见的粘膜色素沉着的鉴别诊断]。
4区 医学
Hautarzt Pub Date : 2022-04-01 Epub Date: 2021-06-25 DOI: 10.1007/s00105-021-04845-x
Sören Korsing, Marcel Boede, Schokufe Ebrahimsade, Katharina Meier
{"title":"[Laugier-Hunziker syndrome : A rare differential diagnosis of mucocutaneous hyperpigmentation].","authors":"Sören Korsing,&nbsp;Marcel Boede,&nbsp;Schokufe Ebrahimsade,&nbsp;Katharina Meier","doi":"10.1007/s00105-021-04845-x","DOIUrl":"https://doi.org/10.1007/s00105-021-04845-x","url":null,"abstract":"<p><p>Laugier-Hunziker syndrome (LHS) is characterized by lentiginous hyperpigmentation of the oral mucosa and lips. In addition, longitudinal melanonychia and palmoplantar hyperpigmented lesions may occur. LHS is a clinical diagnosis of exclusion. Herein, we report the case of a 66-year-old woman with LHS. The clinical and histopathologic features of LHS are presented and important differential diagnoses are discussed.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 4","pages":"298-302"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s00105-021-04845-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39107269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Verzögerte Lokalreaktion mit subkutaner Infiltration nach Impfung mit mRNA-1273 – ein bisher unbeschriebenes Reaktionsmuster eines COVID-Arms 免疫系统中细胞输入mri 1273疫苗后推迟反应
4区 医学
Hautarzt Pub Date : 2022-03-31 DOI: 10.1007/s00105-022-04986-7
L. Kofler, S. Forchhammer
{"title":"Verzögerte Lokalreaktion mit subkutaner Infiltration nach Impfung mit mRNA-1273 – ein bisher unbeschriebenes Reaktionsmuster eines COVID-Arms","authors":"L. Kofler, S. Forchhammer","doi":"10.1007/s00105-022-04986-7","DOIUrl":"https://doi.org/10.1007/s00105-022-04986-7","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"139 1","pages":"488 - 490"},"PeriodicalIF":0.0,"publicationDate":"2022-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72641306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behandlung der Phlegmone 痰的治疗
4区 医学
Hautarzt Pub Date : 2022-03-29 DOI: 10.1007/s00105-022-04978-7
R. Rongisch, M. Fabri
{"title":"Behandlung der Phlegmone","authors":"R. Rongisch, M. Fabri","doi":"10.1007/s00105-022-04978-7","DOIUrl":"https://doi.org/10.1007/s00105-022-04978-7","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"308 - 308"},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48180435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sonnenschutz: Wichtiger denn je! 防晒霜：比以往任何时候都重要！
4区 医学
Hautarzt Pub Date : 2022-03-29 DOI: 10.1007/s00105-022-04964-z
C. Surber, J. Krutmann
{"title":"Sonnenschutz: Wichtiger denn je!","authors":"C. Surber, J. Krutmann","doi":"10.1007/s00105-022-04964-z","DOIUrl":"https://doi.org/10.1007/s00105-022-04964-z","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"249 - 250"},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51862966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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