HautarztPub Date : 2022-05-01Epub Date: 2021-09-14DOI: 10.1007/s00105-021-04883-5
Alexander Thiem, Cristina Has, Anja Diem, Alfred Klausegger, Henning Hamm, Steffen Emmert
{"title":"[Wound therapy with cold atmospheric plasma in severe recessive dystrophic epidermolysis bullosa : A pilot study].","authors":"Alexander Thiem, Cristina Has, Anja Diem, Alfred Klausegger, Henning Hamm, Steffen Emmert","doi":"10.1007/s00105-021-04883-5","DOIUrl":"https://doi.org/10.1007/s00105-021-04883-5","url":null,"abstract":"<p><strong>Background: </strong>Cold atmospheric pressure plasma (CAP) has antimicrobial and wound-healing properties. Patients affected by severe autosomal recessive dystrophic epidermolysis bullosa (RDEB) suffer from widespread, difficult-to-treat wounds, which require complex wound management.</p><p><strong>Objective: </strong>In a pilot project, we investigated over a period of 5 months the response and tolerability of a CAP wound therapy in a 21-year-old and a 28-year-old female patient with severe generalized RDEB and following cutaneous squamous cell cancer (cSSC) in the older patient.</p><p><strong>Materials and methods: </strong>In both patients, diagnosis of RDEB was confirmed by molecular genetics. Individual- and patient-specific wound therapy was continued during the study period, and additionally CAP therapy with a dielectric barrier discharge (DBE) device was initiated. CAP treatment was performed for 90 s per wound and could be applied every day or every other day. Clinical evaluation included photographic documentation and regular interviews of patients and parents.</p><p><strong>Results: </strong>CAP-treated wounds largely demonstrated improved wound healing and signs of a reduced bacterial contamination. Furthermore, CAP proved to prevent wound chronification. When applied on a polyester mesh, it was well-tolerated on most body sites.</p><p><strong>Conclusion: </strong>The introduction of CAP could improve the wound management of EB patients and should be evaluated in clinical studies. The effect of CAP on cSSC development should be particularly studied.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 5","pages":"384-390"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39414782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-28DOI: 10.1007/s00105-022-04982-x
Inbar Kobal, Y. Ramot
{"title":"Januskinaseinhibitoren in der Therapie der Alopecia areata","authors":"Inbar Kobal, Y. Ramot","doi":"10.1007/s00105-022-04982-x","DOIUrl":"https://doi.org/10.1007/s00105-022-04982-x","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"336 - 343"},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46491839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-27DOI: 10.1007/s00105-022-04991-w
Manuel Reinhart, D. Metze, S. Braun
{"title":"Hautveränderungen bei COVID-19 und nach COVID-19-Impfung","authors":"Manuel Reinhart, D. Metze, S. Braun","doi":"10.1007/s00105-022-04991-w","DOIUrl":"https://doi.org/10.1007/s00105-022-04991-w","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"22 1","pages":"434 - 441"},"PeriodicalIF":0.0,"publicationDate":"2022-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77753682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-20DOI: 10.1007/s00105-022-04997-4
R. Rongisch, M. Fabri
{"title":"[Erratum to: Soft tissue infections].","authors":"R. Rongisch, M. Fabri","doi":"10.1007/s00105-022-04997-4","DOIUrl":"https://doi.org/10.1007/s00105-022-04997-4","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51863053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-15DOI: 10.1007/s00105-022-04987-6
J. Burghaus, R. Schneiderbauer, F. Toberer
{"title":"[Pseudoxanthoma elasticum: the dermatologist as a guide].","authors":"J. Burghaus, R. Schneiderbauer, F. Toberer","doi":"10.1007/s00105-022-04987-6","DOIUrl":"https://doi.org/10.1007/s00105-022-04987-6","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72478822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-15DOI: 10.31729/jnma.7424
Chandra Kala Rai, Rita Kafle, Sarbada Makaju
{"title":"Hypertension among Current Cigarette Smokers Visiting Outpatient Department of a Tertiary Care Centre: A Descriptive Cross-sectional Study.","authors":"Chandra Kala Rai, Rita Kafle, Sarbada Makaju","doi":"10.31729/jnma.7424","DOIUrl":"10.31729/jnma.7424","url":null,"abstract":"<p><strong>Introduction: </strong>Hypertension is a common physical condition with high blood pressure for a prolonged period. Long risk factors like age, overweight, high dietary salt intake, smoking, sedentary lifestyle, and term hypertension might lead to various cardiovascular diseases. The normal blood pressure, systolic, is 90-119 mm Hg and diastolic 60-79 mm Hg. The objective of this study is to find out the prevalence of hypertension among current cigarette smokers patients in an outpatient department of a tertiary care centre.</p><p><strong>Methods: </strong>A descriptive cross-sectional study was done on 385 outpatient department patients in a tertiary care centre from September, 2021 to February, 2022. The sample was collected by a convenience after approval from the Institutional Review Committee (Reference number: 0505202105). Outpatient department patients who had past history of smoking cigarette>100 cigarettes and who is still smoking were included in the study. Data were analysed by using the Statistical Package for the Social Science software version 16.0. Point estimate at 95% Confidence Interval was calculated along with frequency and percentage for binary data and mean and standard deviation for continuous data.</p><p><strong>Results: </strong>Among 385 patients, 209 (54.28%) (47.64-60.92 at 95% Confidence Interval) were hypertensive patients. One hundred fifty-six (40.51%) males and 53 (13.76%) females were hypertensive.</p><p><strong>Conclusions: </strong>The prevalence of hypertension was higher when compared to other studies done in similar settings.</p><p><strong>Keywords: </strong>habits; hypertension; prevalence; smokers.</p>","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"63 1","pages":"381-383"},"PeriodicalIF":0.5,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9252244/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73474636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HautarztPub Date : 2022-04-01DOI: 10.1007/s00105-022-04979-6
P. Gressenberger, D. Kopera
{"title":"Plättchenreiches Plasma (PRP) zur Behandlung der androgenetischen Alopezie (AGA): ein aktueller Literaturüberblick","authors":"P. Gressenberger, D. Kopera","doi":"10.1007/s00105-022-04979-6","DOIUrl":"https://doi.org/10.1007/s00105-022-04979-6","url":null,"abstract":"","PeriodicalId":12970,"journal":{"name":"Hautarzt","volume":"73 1","pages":"353 - 357"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51862998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}