纳米是大的!:关于纳米颗粒紫外线过滤器的事实和神话]。

4区 医学 Q3 Medicine
Hautarzt Pub Date : 2022-04-01 Epub Date: 2022-02-21 DOI:10.1007/s00105-022-04954-1
Christian Surber, James Plautz, Uli Osterwalder
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引用次数: 2

摘要

自20世纪50年代以来,含有无机微粉二氧化钛(TiO2)和氧化锌(ZnO)的防晒产品就已经上市了。它们的化妆品接受度仍然有限,因为它们在皮肤上一直是白色的糊状物。通过将颗粒的尺寸减小到100 nm以下的纳米范围,降低了它们反射可见光的光学性能。2000年以后,开发了这种尺寸范围的有机过滤器。当时流行的对纳米技术的热情并没有转移到带有纳米颗粒过滤器的防晒霜产品上。消费者怀疑这些微粒渗入皮肤,被血液吸收,并在全身传播,导致疾病。尤其是由于公众的压力,化妆品——包括防晒产品——成为第一个产品领域,相应地生产的物质受到严格的监管。尽管对纳米颗粒过滤器进行了先进的监管和严格的审批程序,公众的保留意见仍然存在。造成这种情况的可能原因是缺乏知识或对适用立法的不信任,对防晒产品中纳米粒子的行为的认识不清楚,因此对危害、风险和暴露的认识不清楚。在此背景下,本文讨论了防晒霜中纳米颗粒过滤器的性质和行为,以及确保纳米颗粒过滤器和含有纳米颗粒的产品安全使用的监管框架。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

[Nano is big! : Facts and myths about nanoparticulate UV filters].

[Nano is big! : Facts and myths about nanoparticulate UV filters].

[Nano is big! : Facts and myths about nanoparticulate UV filters].

[Nano is big! : Facts and myths about nanoparticulate UV filters].

Sunscreen products containing inorganic micronized titanium dioxide (TiO2) and zinc oxide (ZnO) have been available since the 1950s. Their cosmetic acceptance remained limited as they persist as a white paste on the skin. By reducing the size of the particles into the nano-range below 100 nm, their optical property of reflecting visible light is reduced. After the year 2000, organic filters of this size range were developed. The enthusiasm for nanotechnology that prevailed at the time did not transfer to sunscreen products with nanoparticulate filters. Consumers suspect that the particles permeate the skin, are absorbed by the blood, and spread throughout the body causing illness. Not least due to public pressure, cosmetics-which include sunscreen products-became the first product segment in which accordingly manufactured substances were subjected to strict regulations. Despite advanced regulation and strict approval procedures for nanoparticulate filters, public reservations remained. Possible reasons for this are lack of knowledge or mistrust of the applicable legislation, unclear perception of the behavior of nanoparticles in sunscreen products and as a result unclear perceptions of hazard, risk, and exposure. Against this background, the nature and behavior of nanoparticulate filters in sunscreens on the skin and potentially in the skin, as well as the regulatory framework that ensure that nanoparticulate filters and the products containing them are safe to use are discussed.

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来源期刊
Hautarzt
Hautarzt 医学-皮肤病学
CiteScore
1.40
自引率
0.00%
发文量
93
审稿时长
4-8 weeks
期刊介绍: Der Hautarzt is an internationally recognized journal informing all dermatologists working in practical or clinical environments about important developments in the field of dermatology including allergology, venereology and related areas. Comprehensive reviews on a specific topical issue focus on providing evidenced based information on diagnostics and therapy. Freely submitted original papers allow the presentation of important clinical studies and serve the scientific exchange. Case reports feature interesting cases and aim at optimizing diagnostic and therapeutic strategies. Review articles under the rubric "Continuing Medical Education" present verified results of scientific research and their integration into daily practice.
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