Hepatobiliary surgery and nutrition最新文献

{"title":"De-escalating local therapies without compromising outcomes: lessons from the COLLISION trial.","authors":"Jessica Albuquerque, Noreen S Siddiqi, Van K Morris, Hop Tran Cao, Iwan Paolucci, Bruno C Odisio","doi":"10.21037/hbsn-2025-238","DOIUrl":"10.21037/hbsn-2025-238","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 4","pages":"647-650"},"PeriodicalIF":7.8,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144951728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An enigmatic abdominal mass presenting 1 year after childbirth.","authors":"Antonio Cubisino, Jules Grégory, Aurélie Beaufrère","doi":"10.21037/hbsn-2025-156","DOIUrl":"10.21037/hbsn-2025-156","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"531-533"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170138/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Emphasis on waiting list management towards better prognosis of all potential liver transplant recipients.","authors":"Yongfa Huang","doi":"10.21037/hbsn-2025-310","DOIUrl":"10.21037/hbsn-2025-310","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"500-501"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic effect of surgical margin in patients undergoing hepatectomy for colorectal liver metastasis.","authors":"Katsunori Sakamoto, Yoichiro Uchida, Kentaro Kadono, Hidenobu Kojima, Asahi Sato, Takashi Ito, Takamichi Ishii, Etsuro Hatano","doi":"10.21037/hbsn-2025-192","DOIUrl":"10.21037/hbsn-2025-192","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"476-481"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking portal hypertension in hepatocellular carcinoma resection: a gradient of risk beyond black and white.","authors":"David Pereyra, Patrick Starlinger","doi":"10.21037/hbsn-2025-213","DOIUrl":"10.21037/hbsn-2025-213","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"490-493"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170036/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When technology fails: the pivotal role of meticulous clinical reasoning in unmasking an invisible colon cancer mimicking chronic ischemic colitis.","authors":"Lisha Jing, Hemiao Xu, Shuai Li, Jingjuan Liu, Jia Xu, Yabing Wang, Qingyang Zhou, Zheng Wang, Kun He","doi":"10.21037/hbsn-2025-152","DOIUrl":"10.21037/hbsn-2025-152","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"515-518"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170140/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ectopic hepatocellular carcinoma in the gallbladder.","authors":"Da-Long Wan, Chen-Guang Hua, Xu Yang, Chen Hu, Qing-Hong Ke, Yan Shen","doi":"10.21037/hbsn-2025-105","DOIUrl":"10.21037/hbsn-2025-105","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"522-525"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170049/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating liver resection outcomes post Y90 TARE with personalized dosimetry in intermediate or advanced hepatocellular carcinoma: a focus on surgical and biliary complications.","authors":"Mohamad Azhar Meerun, Carole Allimant, Valentina Schembri, Margaux Hermida, Christine Latry-Kuhn, Denis Mariano-Goulart, Fabrizio Panaro, Boris Guiu","doi":"10.21037/hbsn-24-151","DOIUrl":"10.21037/hbsn-24-151","url":null,"abstract":"<p><strong>Background: </strong>While preliminary reports on resection following downstaging using transarterial radioembolization (TARE) for intermediate or advanced hepatocellular carcinomas (HCCs) reported promising oncological outcomes, there's a notable gap in the literature concerning post operative morbidity. Contrary to post hepatectomy liver failure (PHLF), damages to the bile ducts and their potential consequences have been poorly evaluated. Thus, our aim was to explore postoperative complications in HCC patients undergoing liver resection after Y90 TARE, focusing particularly on biliary complications.</p><p><strong>Methods: </strong>Conducted from June 2015 to December 2022, this retrospective study involved 30 HCC patients undergoing liver resection post-TARE. Comprehensive data on surgical procedures, complications, and follow-up were collected. Logistic regression analyses were conducted, starting with univariate analysis followed by multivariate analysis, focusing on variables with a significance level below P<0.2.</p><p><strong>Results: </strong>The objective response rate (ORR) in the TARE-treated area was 97% at 3 months. Survival outcomes showed a median overall survival (OS) of 5.1 years and progression-free survival (PFS) of 3.5 years post-liver resection. The study found a 40% (12 out of 30 patients) rate of severe postoperative complications and a 7% (2 out of 30 patients) 90-day mortality rate. After liver resection, grade B bile leaks occurred in 20% (6 out of 30) of patients, with a third experiencing recurrence. Biliary-specific mortality was 9%. After multivariate analysis, only the interval between TARE and surgery emerged a significant risk factor for biliary complications, showing increased odds of bile leaks if surgery occurred 3-6 months post-TARE compared to after 6 months.</p><p><strong>Conclusions: </strong>This study highlights the importance of timing between TARE and surgery, suggesting a waiting period of at least 6 months. Such timing not only enhances the radiation effects of TARE but also optimizes both future liver remnant growth and patient selection.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"398-410"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expanding the horizons of cytoreductive surgery-hyperthermic intraperitoneal chemotherapy and liver resection for colorectal peritoneal and liver metastases.","authors":"Yoshimasa Gohda, Norihiro Kokudo","doi":"10.21037/hbsn-2025-189","DOIUrl":"10.21037/hbsn-2025-189","url":null,"abstract":"","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"473-475"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Splenic hypertrophy predicts liver-specific complications in patients undergoing major liver resection for colorectal liver metastases, after preoperative chemotherapy.","authors":"Gerrit Josephs, Lea Hitpass, Daniel Truhn, Franziska Meister, Marie-Luise Berres, Tom Luedde, Danny Jonigk, Steven W M Olde Damink, Sven Arke Lang, Florian Vondran, Iakovos Amygdalos","doi":"10.21037/hbsn-24-121","DOIUrl":"10.21037/hbsn-24-121","url":null,"abstract":"<p><strong>Background: </strong>In patients with colorectal liver metastases (CRLM), preoperative chemotherapy may increase resectability and survival outcomes. However, cytotoxic agents can also cause chemotherapy-associated liver injury (CALI), leading to increased rates of postoperative complications. This study evaluates the association between splenic hypertrophy (SH) after preoperative chemotherapy and postoperative liver-specific complications (LSC), in patients undergoing major liver resection for CRLM.</p><p><strong>Methods: </strong>This retrospective study included patients who underwent major curative liver resection of CRLM following preoperative chemotherapy at the University Hospital RWTH Aachen (UH-RWTH) between 2010-2021. Patients with missing radiological images, incomplete data on chemotherapy regimens, or prior splenectomy were excluded. Volumetric measurements of the spleen were performed on preoperative computerized tomography (CT) and magnetic resonance imaging (MRI) images, using segmentation software (3D-Slicer). Receiver-operating characteristic (ROC) analysis was performed to determine the optimal SH cut-off for predicting postoperative LSC. Independent risk factors of postoperative LSC were examined using logistic regression.</p><p><strong>Results: </strong>A total of 115 patients were included in the study, of which 78 (68%) received oxaliplatin as part of their preoperative chemotherapy regimen. A threshold of 8.6% SH (Youden Index =0.25) was identified as predictive of postoperative LSC. Patients with SH >8.6% (n=62) received oxaliplatin significantly more often (84% <i>vs.</i> 49%; P<0.001) and exhibited higher rates of liver fibrosis (72% <i>vs.</i> 52%, P=0.03) and LSC (63% <i>vs.</i> 38%, P=0.007). Multivariable logistic regression analysis identified SH >8.6% as an independent risk factor for LSC (odds ratio 2.86, 95% confidence interval: 1.104-7.402, P=0.03).</p><p><strong>Conclusions: </strong>Preoperative SH may be a valuable predictor of postoperative LSC in patients undergoing major liver resection for CRLM, following chemotherapy. Further studies are necessary to investigate the impact on a larger cohort and find preventive strategies to mitigate and treat CALI.</p>","PeriodicalId":12878,"journal":{"name":"Hepatobiliary surgery and nutrition","volume":"14 3","pages":"411-422"},"PeriodicalIF":6.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}